General Information of Drug (ID: DMVG9YN)

Drug Name
Fencamfamine
Synonyms
Euvitol; Fenacamfamin; Fencamfamin; Fencamfamina; Fencamfaminum; Fencanfamina; Reactivan; Fencamfamina [DCIT]; Fencamfamin (INN); Fencamfamin [INN:BAN]; Fencamfamine [INN-French]; Fencamfaminum [INN-Latin]; Fencanfamina [INN-Spanish]; Glucoenergan (TN); Reactivan (TN); N-ethyl-2-phenylbicyclo[2.2.1]heptan-3-amine; N-ethyl-3-phenylbicyclo(2.2.1)heptan-2-amine; 2-Ethylamino-3-phenylnorbornane; 2-Phenyl-3-ethylaminobicyclo(2.2.1)heptane; 2-ethylamino-3-phenylnorcamphane; 3-Phenyl-N-ethyl-2-norbornanamine
Indication
Disease Entry ICD 11 Status REF
Depressive fatigue MG22 Withdrawn from market [1]
Therapeutic Class
Central Nervous System Stimulants
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 215.33
Logarithm of the Partition Coefficient (xlogp) 3.3
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 1
Chemical Identifiers
Formula
C15H21N
IUPAC Name
N-ethyl-3-phenylbicyclo[2.2.1]heptan-2-amine
Canonical SMILES
CCNC1C2CCC(C2)C1C3=CC=CC=C3
InChI
InChI=1S/C15H21N/c1-2-16-15-13-9-8-12(10-13)14(15)11-6-4-3-5-7-11/h3-7,12-16H,2,8-10H2,1H3
InChIKey
IKFBPFGUINLYQI-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
14584
ChEBI ID
CHEBI:134895
CAS Number
1209-98-9
DrugBank ID
DB01463
TTD ID
D0P3DM

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dopamine D2 receptor (D2R) TTEX248 DRD2_HUMAN Agonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Depressive fatigue
ICD Disease Classification MG22
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Dopamine D2 receptor (D2R) DTT DRD2 2.50E-02 -0.08 -0.49
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Drug information of Fencamfamine, 2008. eduDrugs.
2 Dopamine uptake inhibiting versus dopamine releasing properties of fencamfamine: an in vitro study. Biochem Pharmacol. 1983 Aug 1;32(15):2329-31.