Details of the Drug

General Information of Drug (ID: DMW03YD)

Drug Name
Lecanemab
Synonyms BAN2401; 1260393-98-3; 12PYH0FTU9; UNII-12PYH0FTU9
Indication
Disease Entry ICD 11 Status REF
Alzheimer disease 8A20 Approved [1]
Drug Type
Antibody
Cross-matching ID
CAS Number
1260393-98-3
DrugBank ID
DB14580
TTD ID
D06XVR

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Amyloid beta A4 protein (APP) TTE4KHA A4_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Alzheimer disease
ICD Disease Classification 8A20
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Amyloid beta A4 protein (APP) DTT APP 1.60E-02 -0.07 -0.31
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 761269.
2 The murine version of BAN2401 (mAb158) selectively reduces amyloid-beta protofibrils in brain and cerebrospinal fluid of tg-ArcSwe mice. J Alzheimers Dis. 2015;43(2):575-88.