Details of the Drug

General Information of Drug (ID: DMW5PKM)

Drug Name

PR-619

Synonyms

2645-32-1; 3,5-dithiocyanatopyridine-2,6-diamine; PR 619; (2,6-diamino-5-thiocyanatopyridin-3-yl) thiocyanate; 2,6-Diamino-3,5-dithiocyanopyridine; Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester; Thiocyanic acid, C,C'-(2,6-diamino-3,5-pyridinediyl) ester; Maybridge3_003257; CHEMBL4303622; SCHEMBL13024499; AOB1115; DTXSID00384716; EX-A179; BDBM442822; HMS1440E01; HMS3653C09; HMS3874D13; BCP07903; MFCD00830384; s7130; ZINC95725713; AKOS024464520; CCG-266746; CS-1513; QC-8206; 2,6-Diamino-3,5-bisthiocyanatopyridine; IDI1_014644; NCGC00371134-01; AK161038; AS-16618; DA-27532; HY-13814; 3,5-Bis-thiocyanato-pyridine-2,6-diamine; AB0004100; PR-619, >=95% (HPLC); FT-0707844; SW208365-2; EC-000.2543; 2,6-Diamino-3,5-dithiocyanato-pyridin, 98%; 2,6-Diaminopyridine-3,5-diyl bis(thiocyanate); A13190; W-5126; (2,6-diamino-5-thiocyanato-3-pyridyl) thiocyanate; 2,6-Diamino-3,5-bis(thiocyanato)pyridine, PR-619; {[2,6-DIAMINO-5-(CYANOSULFANYL)PYRIDIN-3-YL]SULFANYL}FORMONITRILE

Indication

Disease Entry	ICD 11	Status	REF
Esophageal squamous cell carcinoma	2E60.1	Preclinical	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C7H5N5S2
Canonical SMILES: C1=C(C(=NC(=C1SC#N)N)N)SC#N
InChI: 1S/C7H5N5S2/c8-2-13-4-1-5(14-3-9)7(11)12-6(4)10/h1H,(H4,10,11,12)
InChIKey: ZXOBLNBVNROVLC-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 2817763
CAS Number: 2645-32-1
TTD ID: DV59ZT

References

1	Emerging therapies targeting the ubiquitin proteasome system in cancer. J Clin Invest. 2014 Jan;124(1):6-12.