General Information of Disease (ID: DIS5N2GV)

Disease Name Esophageal squamous cell carcinoma
Synonyms
esophagus squamous cell carcinoma; oesophagus squamous cell carcinoma; scc of esophagus; esophageal squamous cell cancer; esophageal squamous cell carcinoma; scc of the oesophagus; esophagus scc; oesophagus scc; scc of oesophagus; squamous cell carcinoma of the esophagus; squamous cell car. - esophagus; squamous cell carcinoma of the oesophagus; squamous cell carcinoma of oesophagus; scc of the esophagus; ESCC; squamous cell car. - oesophagus; esophageal scc; squamous cell carcinoma of esophagus; esophageal epidermoid carcinoma
Disease Class 2E60: Oral cavity/oesophagus/stomach in situ carcinoma
Definition Esophageal squamous cell carcinoma (ESCC) is a type of esophageal carcinoma (EC) that can affect any part of the esophagus, but is usually located in the upper or middle third.
Disease Hierarchy
DISQVIFL: Squamous cell carcinoma
DISS6G4D: Carcinoma of esophagus
DIS5N2GV: Esophageal squamous cell carcinoma
ICD Code
ICD-11
ICD-11: 2E60.1
ICD-10
ICD-10: D00.1
ICD-9
ICD-9: 150
Expand ICD-9
150
Disease Identifiers
MONDO ID
MONDO_0005580
MESH ID
D000077277
UMLS CUI
C0279626
MedGen ID
124635
Orphanet ID
99977
SNOMED CT ID
276804009

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 3 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Cisplatin DMRHGI9 Approved Small molecular drug [1]
Fluorouracil DMUM7HZ Approved Small molecular drug [2]
Toripalimab DMSGA6Z Approved in China Monoclonal antibody [3]
------------------------------------------------------------------------------------
This Disease is Treated as An Indication in 3 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
INCSHR1210 DMZA2K0 Phase 3 Monoclonal antibody [4]
PDR001 DM53J6B Phase 3 Antibody [5]
RO7121661 DM8A120 Phase 2 Antibody [6]
------------------------------------------------------------------------------------
This Disease is Treated as An Indication in 1 Preclinical Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
PR-619 DMW5PKM Preclinical Small molecular drug [7]
------------------------------------------------------------------------------------
This Disease is Treated as An Indication in 1 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Deguelin DMXT7WG Investigative Small molecular drug [8]
------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 409 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
BMI1 TTIPNSR Limited Altered Expression [9]
BSG TT5UJWD Limited Biomarker [10]
CCN1 TTPK79J Limited Biomarker [11]
CEACAM3 TTPX7I5 Limited Biomarker [12]
CEACAM5 TTY6DTE Limited Biomarker [13]
CREBBP TTFRCTK Limited Altered Expression [14]
CRP TTWRN6M Limited Biomarker [15]
EGF TTED8JB Limited Altered Expression [16]
ENG TTB30LE Limited Biomarker [17]
EPHB2 TTKPV6O Limited Biomarker [18]
ERBB4 TTWALCO Limited Biomarker [19]
EZH2 TT9MZCQ Limited Biomarker [20]
FBXW7 TT29KY7 Limited Altered Expression [21]
FGF4 TTCEKVZ Limited Biomarker [22]
FOSL1 TTY8LZG Limited Altered Expression [23]
GSTP1 TT40K12 Limited Altered Expression [24]
HOXA5 TTXSVQP Limited Biomarker [25]
IFNW1 TTS2TGF Limited Genetic Variation [26]
IL2RB TT9721Y Limited Altered Expression [27]
KDM1A TTNR0UQ Limited Biomarker [28]
KDM4C TTV8CRH Limited Altered Expression [29]
MTDH TTH6SA5 Limited Altered Expression [30]
MUC1 TTBHFYQ Limited Altered Expression [31]
PDE4D TTSKMI8 Limited Genetic Variation [32]
PIK3CB TT9H4P3 Limited Biomarker [33]
SKP2 TT5B2EO Limited Altered Expression [34]
SLC39A6 TTZN1CF Limited Altered Expression [35]
SMYD3 TTKLJYX Limited Biomarker [36]
SOD2 TT9O4C5 Limited Biomarker [37]
STAT1 TTN7R6K Limited Genetic Variation [38]
STMN1 TT7W5OT Limited Biomarker [39]
TCF3 TTULOD8 Limited Altered Expression [27]
TWIST1 TTX1MY7 Limited Altered Expression [40]
VEGFC TT0QUFV Limited Altered Expression [41]
CCR7 TT2GIDQ Disputed Biomarker [42]
CD47 TT28S46 Disputed Biomarker [43]
LILRB1 TTC0QRJ Disputed Biomarker [44]
PTK2 TTON5IT Disputed Altered Expression [45]
EGFR TTGKNB4 moderate Biomarker [46]
ABCC2 TTFLHJV Strong Biomarker [47]
ADAM9 TTTYQNS Strong Biomarker [48]
ADH1A TT5AHZ0 Strong Altered Expression [49]
ADH7 TT3LE7P Strong Biomarker [50]
AGK TTJETQC Strong Altered Expression [51]
AHCY TTE2KUJ Strong Altered Expression [52]
AKT3 TTO6SGY Strong Altered Expression [53]
ALOX12 TT12ABZ Strong Biomarker [54]
ALOX15 TTN9T81 Strong Biomarker [54]
ANO1 TTOJI4S Strong Biomarker [55]
ANXA1 TTUCK4B Strong Biomarker [56]
ANXA10 TT0NL6U Strong Biomarker [57]
ANXA5 TT2Z83I Strong Biomarker [58]
APLNR TTJ8E43 Strong Biomarker [59]
APOB TTN1IE2 Strong Biomarker [60]
AQP3 TTLDNMQ Strong Altered Expression [61]
ASPH TT2KHP7 Strong Biomarker [62]
ATAD2 TT9A0HI Strong Altered Expression [63]
ATF4 TTQCKWT Strong Biomarker [64]
ATG7 TTLVB9Z Strong Biomarker [65]
ATP1A1 TTWK8D0 Strong Altered Expression [66]
AURKA TTPS3C0 Strong Altered Expression [67]
AURKB TT9RTBL Strong Biomarker [8]
AZGP1 TTUPYLV Strong Biomarker [68]
B2M TTY7FKA Strong Altered Expression [69]
BAGE TTS5GLJ Strong Altered Expression [70]
BCAT1 TTES57P Strong Altered Expression [71]
BGN TT0JPVF Strong Altered Expression [72]
BIRC2 TTQ5LRD Strong Biomarker [73]
BST2 TT90BJT Strong Biomarker [74]
CA2 TTANPDJ Strong Altered Expression [75]
CACNA1C TTZIFHC Strong Biomarker [76]
CACNA2D3 TTN7T29 Strong Biomarker [33]
CALCR TTLWS2O Strong Biomarker [77]
CALR TTUZ7OA Strong Biomarker [77]
CASP4 TT6KIOT Strong Biomarker [78]
CCK TT90CMU Strong Biomarker [79]
CCL21 TTLZK1U Strong Biomarker [42]
CCNA2 TTAMQ62 Strong Altered Expression [80]
CCND1 TTFCJ7S Strong Biomarker [81]
CD163 TTTZ9DE Strong Biomarker [82]
CD3E TTZAT79 Strong Biomarker [83]
CDC25A TTLZS4Q Strong Biomarker [84]
CDC7 TTSMTDI Strong Biomarker [85]
CDK2 TT7HF4W Strong Altered Expression [86]
CDK7 TTQYF7G Strong Biomarker [87]
CDKN1A TT9GUW0 Strong Genetic Variation [88]
CHEK1 TTTU902 Strong Biomarker [89]
CHEK2 TT9ABMF Strong Genetic Variation [90]
CHKA TT10AWB Strong Biomarker [91]
CHRNA7 TTLA931 Strong Altered Expression [92]
CHRNB4 TTTVAFQ Strong Altered Expression [92]
CHST15 TTFK7E1 Strong Biomarker [93]
CLDN4 TTMTS9H Strong Biomarker [94]
CLIC1 TT8KZG6 Strong Altered Expression [95]
CLK2 TT85TPS Strong Biomarker [96]
CNTN1 TTPR8FK Strong Altered Expression [97]
COL7A1 TTBCOKN Strong Altered Expression [98]
COPS5 TTSTNJR Strong Biomarker [99]
CTAG1A TTE5ITK Strong Biomarker [40]
CTCFL TTY0RZT Strong Altered Expression [100]
CUL3 TTPCU0Q Strong Biomarker [101]
CYP11A1 TTSYVO6 Strong Genetic Variation [102]
CYP1B1 TTI84H7 Strong Genetic Variation [103]
CYP24A1 TT82UI1 Strong Genetic Variation [104]
CYP2A6 TTAQ6ZW Strong Genetic Variation [105]
CYP2C19 TTZ58XG Strong Genetic Variation [106]
CYP2C9 TTR40YJ Strong Altered Expression [107]
CYSLTR2 TT0PZR5 Strong Biomarker [108]
DCK TTJOCE4 Strong Altered Expression [109]
DEFB4A TTIVY12 Strong Biomarker [110]
DEK TT1NMGV Strong Altered Expression [111]
DEPTOR TTLYP6D Strong Biomarker [112]
DFFA TTYVQ9C Strong Altered Expression [113]
DGKA TTGL8F0 Strong Biomarker [114]
DHPS TTBO2A9 Strong Altered Expression [115]
DKK3 TTY2ZV6 Strong Biomarker [116]
DTL TT8396I Strong Biomarker [117]
E2F1 TTASI04 Strong Altered Expression [118]
ECE1 TTQ9RYT Strong Altered Expression [119]
EEF2K TT1QFLA Strong Altered Expression [120]
EGFL7 TT7WD0H Strong Posttranslational Modification [48]
EIF4E TTZGCP6 Strong Biomarker [121]
EP300 TTGH73N Strong Altered Expression [122]
EPCAM TTZ8WH4 Strong Altered Expression [27]
EPHA1 TTLFZVU Strong Altered Expression [123]
EPHA2 TTRJB2G Strong Altered Expression [124]
EPHA3 TTHS2LR Strong Biomarker [125]
EYA2 TTUY9C6 Strong Biomarker [126]
F2RL3 TTD0652 Strong Biomarker [127]
FASN TT7AOUD Strong Biomarker [128]
FAT1 TTGUJYV Strong Genetic Variation [129]
FGF19 TTGCH11 Strong Biomarker [130]
FGFR4 TT1KX2S Strong Altered Expression [131]
FHIT TTMS54D Strong Biomarker [132]
FHL1 TTI7ENL Strong Biomarker [133]
FOXC2 TTLBAP1 Strong Biomarker [134]
FOXM1 TTD3KOX Strong Altered Expression [135]
FOXO1 TTLRVIA Strong Altered Expression [136]
FOXQ1 TTEJZOL Strong Genetic Variation [137]
FUT4 TTNV1KZ Strong Altered Expression [138]
FYN TT2B9KF Strong Biomarker [139]
FZD7 TTUQMO5 Strong Biomarker [140]
GAPDH TTUGSWA Strong Altered Expression [141]
GCH1 TTLSWP6 Strong Biomarker [142]
GGH TTZJRL0 Strong Altered Expression [143]
GHRHR TTG4R8V Strong Altered Expression [144]
GLI1 TTJOMH6 Strong Altered Expression [145]
GPR139 TTOL9B0 Strong Biomarker [146]
GPR39 TTTPCNU Strong Altered Expression [147]
GPRC5D TTHRAPJ Strong Altered Expression [148]
GRIN2B TTN9D8E Strong Posttranslational Modification [149]
HDAC2 TTSHTOI Strong Altered Expression [150]
HDAC6 TT5ZKDI Strong Biomarker [151]
HIF1A TTSN6QU Strong Biomarker [152]
HIPK2 TTOB49C Strong Altered Expression [153]
HLA-G TTLKFB3 Strong Biomarker [154]
HMGA2 TTSTVM0 Strong Biomarker [155]
HMGB1 TTWQYB7 Strong Biomarker [156]
HMGCS2 TTS0EZJ Strong Biomarker [157]
HNF4A TT2F3CD Strong Biomarker [158]
HOXA13 TTN26OM Strong Altered Expression [159]
HOXB13 TTZ6I58 Strong Altered Expression [160]
HSF1 TTN6STZ Strong Altered Expression [161]
HSPA5 TTW26OG Strong Altered Expression [162]
HTRA1 TT8POQR Strong Biomarker [163]
IDO1 TTZJYKH Strong Altered Expression [164]
IGFBP3 TTZHNQA Strong Genetic Variation [165]
IGFBP7 TTUQ01B Strong Biomarker [166]
IL11 TTGUYTR Strong Biomarker [167]
IL15RA TTGN89I Strong Genetic Variation [168]
IL23R TT6H4QR Strong Biomarker [169]
IL7R TTAWI51 Strong Altered Expression [170]
IMP3 TTEJA2R Strong Altered Expression [171]
INHBA TTVB30D Strong Altered Expression [172]
IRF1 TT4TU3L Strong Altered Expression [135]
ISG15 TTVOH3T Strong Biomarker [173]
ITCH TT5SEWD Strong Biomarker [174]
ITGA6 TT165T3 Strong Biomarker [175]
ITGB1 TTBVIQC Strong Biomarker [176]
KAT2B TTVK7SB Strong Biomarker [177]
KCND3 TTPLQO0 Strong Altered Expression [178]
KCNH2 TTQ6VDM Strong Biomarker [179]
KDM4A TTZHPB8 Strong Biomarker [180]
KDM5B TTCLI75 Strong Altered Expression [181]
KHDRBS1 TTAT6C7 Strong Altered Expression [34]
KIF11 TTBGTCW Strong Biomarker [182]
KLF4 TTTI53X Strong Biomarker [183]
KMT5A TTGC95K Strong Biomarker [184]
KRT17 TTKV0EC Strong Altered Expression [185]
LAMP1 TTC214J Strong Altered Expression [186]
LAMP2 TTULDG7 Strong Altered Expression [187]
LAPTM4B TTEJQT0 Strong Genetic Variation [188]
LASP1 TTZJA87 Strong Biomarker [189]
LATS2 TTML7FG Strong Altered Expression [190]
LCN2 TTKTLAI Strong Biomarker [179]
LDHA TTW76JE Strong Altered Expression [191]
LGR5 TTTSGRH Strong Altered Expression [192]
LHCGR TT2O4W9 Strong Biomarker [60]
LIFR TTID542 Strong Biomarker [193]
LIMK1 TTWL9TY Strong Altered Expression [194]
LIN28A TTO50LN Strong Altered Expression [195]
LONP1 TTM1VPZ Strong Biomarker [196]
LOXL2 TTFSUHX Strong Biomarker [197]
LRP6 TTSXOWE Strong Altered Expression [198]
LTA TTP73TM Strong Biomarker [128]
LY6K TT5GKHN Strong Biomarker [199]
LYVE1 TTG8DNU Strong Biomarker [200]
MAGEA1 TT63M7Q Strong Altered Expression [201]
MAGEA3 TTWSKHD Strong Biomarker [202]
MAGEA4 TT9EQUY Strong Biomarker [203]
MAGEA6 TTJIWMO Strong Altered Expression [204]
MANF TT56RYE Strong Genetic Variation [205]
MAP2K7 TT6QY3J Strong Biomarker [206]
MAP3K9 TTUNSIX Strong Altered Expression [207]
MAP4 TT0VFPN Strong Altered Expression [208]
MAPK8 TT0K6EO Strong Biomarker [209]
MASP2 TTR01E9 Strong Altered Expression [210]
MCL1 TTL53M6 Strong Biomarker [211]
MCM7 TT1RM3F Strong Altered Expression [212]
MDM4 TT9OUDQ Strong Biomarker [213]
MFGE8 TT1GLAJ Strong Altered Expression [214]
MGMT TTJ8DV7 Strong Biomarker [215]
MMP10 TTXLEG7 Strong Biomarker [216]
MMP11 TTZW4MV Strong Altered Expression [217]
MMP13 TTHY57M Strong Biomarker [218]
MMP14 TTJ4QE7 Strong Altered Expression [219]
MMP16 TTNP4CU Strong Altered Expression [220]
MMP21 TTYRF5E Strong Altered Expression [154]
MMP3 TTUZ2L5 Strong Biomarker [55]
MSH2 TTCAWRT Strong Genetic Variation [221]
MSI1 TTSM4BA Strong Altered Expression [222]
MSI2 TTTXQF6 Strong Biomarker [223]
MTA1 TTO4HUS Strong Biomarker [206]
MTAP TTDBX7N Strong Altered Expression [224]
MTR TTUTO39 Strong Genetic Variation [225]
MUTYH TTNB0ZK Strong Altered Expression [226]
NCL TTK1V5Q Strong Altered Expression [227]
NDUFAF2 TTCHGVF Strong Altered Expression [228]
NEDD8 TTNDC4K Strong Altered Expression [229]
NELL1 TT7H4BF Strong Biomarker [230]
NGFR TTEDJN4 Strong Biomarker [231]
NLRC5 TTWZC78 Strong Biomarker [232]
NLRP1 TTQX29T Strong Biomarker [233]
NME1 TTDY8JH Strong Biomarker [234]
NOTCH2 TT82FVD Strong Altered Expression [235]
NOTCH3 TTVX7IA Strong Biomarker [28]
NPR1 TTM9IYA Strong Altered Expression [236]
NQO1 TT8XK6L Strong Biomarker [237]
NQO2 TTJLP0R Strong Genetic Variation [238]
NR1H2 TTXA6PH Strong Genetic Variation [239]
NRP2 TTRXUVC Strong Biomarker [240]
ODC1 TTUMGNO Strong Biomarker [241]
OGG1 TTRU01G Strong Altered Expression [242]
ORAI1 TTE76YK Strong Biomarker [243]
PABPC1 TTHC8EF Strong Altered Expression [244]
PADI4 TTQHAXM Strong Altered Expression [245]
PAH TTGSVH2 Strong Biomarker [246]
PARG TT39J16 Strong Altered Expression [127]
PAWR TT3I4WV Strong Biomarker [127]
PDCD1LG2 TTW14O3 Strong Biomarker [247]
PDGFD TTSN0GA Strong Biomarker [248]
PDPK1 TTYMGWX Strong Altered Expression [249]
PDX1 TT8SGZK Strong Altered Expression [250]
PEBP1 TT1BGU8 Strong Biomarker [251]
PFKFB3 TTTHMQJ Strong Altered Expression [252]
PGD TTZ3IFB Strong Altered Expression [253]
PHB TT6U071 Strong Altered Expression [254]
PHGDH TT8DRCK Strong Altered Expression [253]
PIN1 TTJNTSI Strong Altered Expression [255]
PKM TT4LOT8 Strong Biomarker [256]
PKMYT1 TTB4PAZ Strong Altered Expression [257]
PLA2G4A TTT1JVS Strong Altered Expression [258]
PLK1 TTH4IP0 Strong Biomarker [259]
PLOD1 TTEKJP3 Strong Biomarker [260]
PLOD2 TT8MEUD Strong Biomarker [260]
POLB TTA0XPV Strong Biomarker [261]
PRKCI TTWJTHX Strong Altered Expression [262]
PRKD1 TTSLUMT Strong Altered Expression [263]
PRKDC TTK3PY9 Strong Biomarker [264]
PRMT1 TTVOJAI Strong Altered Expression [265]
PRSS8 TTT4N0Q Strong Posttranslational Modification [266]
PSCA TT9T4AV Strong Genetic Variation [267]
PSIP1 TTH9LDP Strong Genetic Variation [88]
PSMB8 TTEAD9J Strong Genetic Variation [268]
PSMB9 TTOUSTQ Strong Genetic Variation [268]
PTGES TTYLQ8V Strong Biomarker [269]
PTGES2 TTWU04I Strong Biomarker [270]
PTGS2 TTVKILB Strong Biomarker [271]
PTK7 TTXH2ZN Strong Biomarker [272]
PTP4A1 TTA8GFO Strong Altered Expression [273]
PTPN1 TTELIN2 Strong Biomarker [46]
RACK1 TTJ10AL Strong Biomarker [274]
RARA TTW38KT Strong Biomarker [275]
RARB TTISP28 Strong Altered Expression [276]
RECK TTRZBW7 Strong Altered Expression [277]
RHCG TTN5MZ3 Strong Biomarker [278]
RICTOR TT143WL Strong Altered Expression [279]
RNF6 TT4S09X Strong Genetic Variation [280]
ROBO1 TTND1YP Strong Biomarker [281]
RPS6KA3 TTUM2ZR Strong Biomarker [282]
RUNX1 TTWIN3H Strong Genetic Variation [283]
RUNX3 TTKCVO7 Strong Altered Expression [284]
S100A4 TTPR5SX Strong Biomarker [285]
S1PR1 TT9JZCK Strong Biomarker [286]
SATB1 TTLFRIC Strong Biomarker [287]
SDC2 TT5H2F0 Strong Altered Expression [288]
SEMA4D TT5UT28 Strong Biomarker [289]
SERPINB5 TT1KW50 Strong Altered Expression [290]
SERPINH1 TTPSWQG Strong Altered Expression [291]
SLC12A1 TTS087L Strong Biomarker [292]
SLC16A3 TTG6VD5 Strong Biomarker [293]
SLC23A2 TTOP832 Strong Genetic Variation [294]
SLC6A8 TTYUHB5 Strong Biomarker [77]
SLC7A5 TTPH2JB Strong Biomarker [295]
SLC9A1 TTGSEFH Strong Biomarker [296]
SLIT2 TTDWK85 Strong Biomarker [281]
SMYD2 TT7YJFO Strong Biomarker [297]
SOCS1 TT8COJM Strong Biomarker [298]
SOX2 TTCNOT6 Strong Altered Expression [9]
SP1 TTZEP6S Strong Biomarker [79]
SPOCK1 TTF23RE Strong Altered Expression [299]
SQLE TTE14XG Strong Biomarker [179]
SREBF2 TTRQ4AP Strong Biomarker [300]
SRGN TTCHB06 Strong Genetic Variation [301]
SRPK1 TTU3WV6 Strong Altered Expression [302]
ST14 TTPRO7W Strong Biomarker [303]
STC1 TTDLUER Strong Altered Expression [304]
STOML2 TTOI329 Strong Altered Expression [305]
SUV39H1 TTUWQTK Strong Biomarker [306]
TAGLN TTDRZ9H Strong Altered Expression [307]
TAGLN2 TTP6BIJ Strong Altered Expression [308]
TAP1 TT7JZI8 Strong Biomarker [268]
TBX21 TTNF9PH Strong Genetic Variation [309]
TDO2 TTXNCBV Strong Altered Expression [310]
TERF1 TT1Y6J2 Strong Altered Expression [311]
TFF1 TTNOJIZ Strong Posttranslational Modification [312]
TGFBR2 TTZE3P7 Strong Posttranslational Modification [313]
THRB TTGER3L Strong Biomarker [314]
TIAM1 TTNU6I5 Strong Biomarker [315]
TMPRSS2 TT1GM2Z Strong Altered Expression [316]
TMSB4X TTMVAIU Strong Altered Expression [317]
TNFRSF10B TTW20TU Strong Biomarker [318]
TNFRSF14 TTWGTC1 Strong Altered Expression [319]
TNFRSF1B TT63WSF Strong Altered Expression [320]
TRIM24 TT9Q7AE Strong Biomarker [321]
TRIM27 TTTO3QN Strong Biomarker [322]
TRIM28 TTQ2BKV Strong Altered Expression [323]
TRPC6 TTRBT3W Strong Biomarker [324]
TRPM7 TTFPVZO Strong Altered Expression [325]
TRPV2 TTBECWA Strong Altered Expression [326]
TRPV6 TTBK14N Strong Altered Expression [327]
TTK TTP7EGM Strong Altered Expression [328]
TUSC2 TTJ8O14 Strong Biomarker [329]
TYMP TTO0IB8 Strong Biomarker [330]
UCHL5 TTSX29Z Strong Altered Expression [331]
UCP1 TTI12YJ Strong Biomarker [332]
ULK1 TT4D7MJ Strong Altered Expression [333]
UMPS TTAFJUD Strong Altered Expression [334]
USP14 TTVSYP9 Strong Altered Expression [331]
USP7 TTXU3EQ Strong Biomarker [335]
VCP TTHNLSB Strong Altered Expression [336]
VIPR2 TT4O5P0 Strong Biomarker [76]
VTCN1 TTCK85E Strong Altered Expression [181]
WAS TTE8T73 Strong Biomarker [337]
WDR5 TT7OFWB Strong Altered Expression [338]
WNK1 TTJ9UMX Strong Altered Expression [339]
XIAP TTK3WBU Strong Biomarker [340]
XRCC5 TTCB9KW Strong Altered Expression [341]
YAP1 TT8UN2D Strong Biomarker [129]
ZAP70 TTUMHT8 Strong Biomarker [342]
ADCYAP1 TTW4LYC Definitive Biomarker [343]
ATF3 TTCE793 Definitive Altered Expression [344]
BMP6 TT07RIB Definitive Altered Expression [345]
CA1 TTHQPL7 Definitive Biomarker [343]
CA9 TT2LVK8 Definitive Biomarker [269]
CCNB1 TT9P6OW Definitive Altered Expression [346]
CDC25B TTR0SWN Definitive Altered Expression [347]
CEBPB TTUI35N Definitive Biomarker [348]
CHRNA5 TTH2QRX Definitive Altered Expression [92]
CRYZ TTP6UO8 Definitive Genetic Variation [238]
CYP3A5 TTHS0OK Definitive Genetic Variation [102]
DSG3 TTEO4P8 Definitive Altered Expression [349]
EIF4EBP1 TTKGEBL Definitive Altered Expression [350]
EIF5A2 TTH53G9 Definitive Biomarker [351]
EPHB4 TTI4ZX2 Definitive Biomarker [352]
ETS2 TT9AH0M Definitive Biomarker [353]
FKBP1A TTMW94E Definitive Biomarker [343]
GLO1 TTV9A7R Definitive Biomarker [343]
GSTO1 TTWO3SH Definitive Biomarker [343]
HAX1 TT21BYA Definitive Altered Expression [354]
HTATIP2 TTC6IX5 Definitive Biomarker [355]
LAMB3 TT2WOUQ Definitive Genetic Variation [356]
MAP3K7 TTJQT60 Definitive Biomarker [76]
MSMB TTYH1ZK Definitive Biomarker [357]
MSR1 TT2TDH9 Definitive Biomarker [358]
NCOA3 TT124R0 Definitive Altered Expression [359]
OSMR TTAH0KM Definitive Altered Expression [193]
PHF8 TT81PFE Definitive Biomarker [360]
PINX1 TT4FJ3A Definitive Altered Expression [361]
PLA2G2A TTO8QRU Definitive Altered Expression [362]
PTK6 TT6TH8V Definitive Altered Expression [363]
PTP4A3 TT7YM8D Definitive Biomarker [364]
RHBDF2 TTH1ZOP Definitive Genetic Variation [365]
SERPINB3 TT6QLPX Definitive Biomarker [343]
STC2 TT4EFTR Definitive Biomarker [133]
TKTL1 TTNQ1J3 Definitive Altered Expression [366]
TPX2 TT0PHL4 Definitive Altered Expression [367]
TRAF6 TTCDR6M Definitive Biomarker [368]
XPO1 TTCJUR4 Definitive Altered Expression [369]
------------------------------------------------------------------------------------
⏷ Show the Full List of 409 DTT(s)
This Disease Is Related to 11 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ABCA12 DT7LDG0 Strong Altered Expression [370]
SLC12A2 DTHKL3Q Strong Altered Expression [292]
SLC22A17 DTXI9E6 Strong Altered Expression [371]
SLC25A20 DTQOUM4 Strong Altered Expression [75]
SLC27A5 DT0TQS3 Strong Biomarker [372]
SLC30A7 DTQK38X Strong Altered Expression [373]
SLC39A5 DTN9ACR Strong Altered Expression [374]
SLC4A1 DTB0Q3P Strong Biomarker [375]
SLC4A2 DTF7GAL Strong Biomarker [376]
SLC9A9 DT8LP62 Strong Altered Expression [377]
SLCO6A1 DTIFXNS Strong Genetic Variation [378]
------------------------------------------------------------------------------------
⏷ Show the Full List of 11 DTP(s)
This Disease Is Related to 31 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
ABO DESIA7R Limited Genetic Variation [379]
ADH1C DEM1HNL Limited Genetic Variation [380]
ACP6 DER6BCE Strong Altered Expression [381]
ACSS2 DEE76VW Strong Altered Expression [382]
ADH1B DEEN9RD Strong Genetic Variation [383]
ADH4 DEOCWU3 Strong Genetic Variation [384]
ADH5 DEIOH6A Strong Genetic Variation [49]
AKR1A1 DED2FW3 Strong Biomarker [385]
AKR1B10 DEP6GT1 Strong Genetic Variation [205]
AKR1C1 DE7P2FB Strong Biomarker [386]
AKR1C2 DEOY5ZM Strong Biomarker [386]
ALDH1A1 DE2JP1Y Strong Altered Expression [271]
BAAT DERA3OF Strong Genetic Variation [387]
CPA4 DEXKD7J Strong Altered Expression [388]
CYP26B1 DEZT8FM Strong Genetic Variation [128]
DCTD DEXL3P2 Strong Genetic Variation [389]
GGCT DEKW6PB Strong Genetic Variation [390]
GSTO2 DEHMPZR Strong Altered Expression [391]
HPGD DEHKSC6 Strong Altered Expression [253]
LAP3 DENZF0O Strong Altered Expression [392]
NAT1 DE7OAB3 Strong Genetic Variation [393]
NAT10 DEZV4AP Strong Biomarker [394]
NNMT DECVGJ3 Strong Biomarker [395]
SULT1A1 DEYWLRK Strong Genetic Variation [396]
SULT1A2 DERUZL7 Strong Genetic Variation [396]
SULT2A1 DE0P6LK Strong Biomarker [342]
UGT1A8 DE2GB8N Strong Altered Expression [397]
UGT2B17 DEAZDL8 Strong Biomarker [398]
UGT2B4 DENUPDX Strong Genetic Variation [397]
UPP1 DEFZWAX Strong Biomarker [399]
PSAT1 DEBS17P Definitive Altered Expression [400]
------------------------------------------------------------------------------------
⏷ Show the Full List of 31 DME(s)
This Disease Is Related to 736 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ABCB10 OT1C44F9 Limited Biomarker [401]
ABI1 OT5H4M62 Limited Altered Expression [402]
ARL6IP5 OTYZ6BEQ Limited Altered Expression [403]
BHLHE40 OTITX14U Limited Altered Expression [404]
CDKN2B OTAG24N1 Limited Genetic Variation [405]
CEACAM7 OTKFDTZY Limited Biomarker [12]
CLPTM1L OTDJWQXI Limited Genetic Variation [406]
COX2 OTTMVBJJ Limited Biomarker [271]
CUX1 OTU1LCNJ Limited Altered Expression [27]
DSC2 OTODVH8K Limited Biomarker [183]
ELAVL2 OT6EJ8MQ Limited Biomarker [407]
FARP2 OTNRQIMK Limited Biomarker [408]
FERMT2 OTZNPWWX Limited Biomarker [409]
FLACC1 OTZN9TZV Limited Genetic Variation [32]
FOXA1 OTEBY0TD Limited Biomarker [126]
HCLS1 OTX7WGYN Limited Altered Expression [27]
KMT2D OTTVHCLY Limited Altered Expression [304]
KRT16 OTGA0EQN Limited Biomarker [410]
LINGO2 OT3N88Q1 Limited Genetic Variation [26]
MAD2L1 OTXNGZCG Limited Altered Expression [411]
MTO1 OT7HCZ1D Limited Biomarker [401]
PSG2 OT2EIXAI Limited Biomarker [12]
PUF60 OTG90DYF Limited Biomarker [408]
RASSF1 OTEZIPB7 Limited Altered Expression [412]
RRM2B OTE8GBUR Limited Biomarker [413]
SFMBT2 OTZQT61Q Limited Biomarker [401]
SIGLEC7 OTNDLURR Limited Altered Expression [27]
SMAD2 OTC6VB4K Limited Altered Expression [414]
SMUG1 OT2YIOCQ Limited Genetic Variation [415]
TBC1D9 OTSSCTB5 Limited Altered Expression [416]
DCTN6 OTI8PIN9 Disputed Altered Expression [417]
IFI27 OTI2XGIT Disputed Altered Expression [417]
MAML1 OTQA4DDN Disputed Biomarker [418]
PSMD9 OT6Y5CC3 Disputed Altered Expression [417]
RETREG1 OTYOSLZX Disputed Biomarker [419]
SRY OT516T6D Disputed Altered Expression [420]
TICAM2 OTK7GIJ5 Disputed Altered Expression [417]
TMED7 OTONO8E6 Disputed Altered Expression [417]
DLG1 OTCRZYWT moderate Biomarker [401]
SHMT1 OTIINA3J moderate Genetic Variation [421]
SPRR1A OTJMI34A moderate Altered Expression [422]
AADAC OT8VACT2 Strong Altered Expression [423]
ABI2 OT8GIIS5 Strong Biomarker [424]
ABRAXAS2 OTAW1I4C Strong Biomarker [64]
ACADL OTP7Y0UF Strong Altered Expression [425]
ACOT7 OT7C68YV Strong Genetic Variation [309]
ACTBL2 OTD6B81U Strong Genetic Variation [309]
ACTG2 OTRDWUO0 Strong Genetic Variation [309]
ACTL6A OT0EC5BQ Strong Biomarker [426]
ACTN4 OTCNZAJ5 Strong Altered Expression [339]
ACTRT1 OTHFKSIZ Strong Biomarker [424]
ADAM12 OTZKOTDB Strong Altered Expression [427]
ADAMTS12 OTG7HEA2 Strong Biomarker [428]
ADAMTS16 OTTKUH99 Strong Altered Expression [429]
ADAMTS6 OTSZE6L4 Strong Altered Expression [430]
ADAMTS9 OTV3Q0DS Strong Biomarker [431]
ADARB1 OTGKSZEV Strong Altered Expression [432]
ADGRG1 OTQBB8NT Strong Altered Expression [148]
AFAP1L2 OTJBI0VN Strong Biomarker [433]
AIFM1 OTKPWB7Q Strong Altered Expression [434]
AJAP1 OTAAW121 Strong Altered Expression [435]
AJUBA OTNW7YPK Strong Genetic Variation [436]
AKAP12 OTCVRDDX Strong Posttranslational Modification [437]
AKT1S1 OT4JHN4Y Strong Biomarker [438]
ALDH7A1 OTV57BZD Strong Genetic Variation [439]
ALG3 OTPOL1QW Strong Altered Expression [440]
AMDHD1 OTBRFQF8 Strong Genetic Variation [389]
ANKRD36B OT3MW415 Strong Altered Expression [441]
APOBEC3B OTHLNI51 Strong Biomarker [442]
ARFGEF3 OTGQV0CU Strong Biomarker [443]
ARFRP1 OTP1OV78 Strong Genetic Variation [205]
ARL6IP1 OT536XAV Strong Biomarker [424]
ASH1L OTUT5NLJ Strong Biomarker [444]
ATP1B2 OTYTBYVU Strong Genetic Variation [32]
AXIN1 OTRGZGZ5 Strong Posttranslational Modification [445]
AZIN1 OTX5W77I Strong Biomarker [446]
AZIN2 OT8OB7CG Strong Biomarker [447]
BAG1 OTRQNIA4 Strong Biomarker [448]
BANF1 OTP7Z38L Strong Biomarker [449]
BARX1 OT2VP73H Strong Biomarker [450]
BCCIP OTFFKG79 Strong Altered Expression [451]
BCL10 OT47MCLI Strong Biomarker [452]
BEX1 OTBQIF0H Strong Altered Expression [453]
BHLHE41 OTY9GJ1Y Strong Biomarker [454]
BIN1 OTK8O0X8 Strong Posttranslational Modification [455]
BIRC6 OTCQJAB0 Strong Biomarker [456]
BMF OT90NSLI Strong Biomarker [457]
BMS1 OTEGQ8ZO Strong Genetic Variation [309]
BPTF OTD1RZAD Strong Biomarker [458]
BRAP OTB7BAFQ Strong Altered Expression [459]
BRF2 OT2C6TH2 Strong Biomarker [460]
BRI3BP OTWCFPRM Strong Altered Expression [461]
BRINP1 OTEUVSCP Strong Altered Expression [462]
BTRC OT2EZDGR Strong Biomarker [463]
BUB1B OT8KME51 Strong Biomarker [464]
C1GALT1 OT2ZSZ6P Strong Biomarker [465]
CADM1 OTRWG9QS Strong Altered Expression [466]
CADM2 OT45PVKC Strong Altered Expression [467]
CAP1 OTYM8A2N Strong Biomarker [468]
CAPN10 OTS9LJW4 Strong Altered Expression [469]
CAPN3 OTCHG3YK Strong Biomarker [470]
CAPNS1 OT95EBBD Strong Altered Expression [471]
CAPS OTC9GZ2M Strong Biomarker [472]
CAV2 OT1FGRQX Strong Altered Expression [473]
CBX8 OT4U5V1T Strong Biomarker [474]
CCAR2 OTLUDG5T Strong Altered Expression [462]
CCDC34 OTZ3AGSQ Strong Altered Expression [475]
CCDC54 OTW5WCX9 Strong Altered Expression [476]
CCHCR1 OT22C116 Strong Biomarker [128]
CCL1 OT23NON8 Strong Genetic Variation [477]
CCL26 OT2B7HR9 Strong Biomarker [478]
CCL28 OTY6XNQ7 Strong Altered Expression [479]
CCL8 OTCTWYN8 Strong Biomarker [480]
CCN5 OTADU8JJ Strong Altered Expression [481]
CCNA1 OTX4HD45 Strong Biomarker [482]
CCNG1 OT17IA9L Strong Biomarker [483]
CCS OTXHT3QO Strong Biomarker [484]
CCT8 OTA7GQN9 Strong Altered Expression [485]
CD63 OT2UGZA9 Strong Biomarker [486]
CD82 OTH8MC64 Strong Biomarker [487]
CDC34 OTNBK390 Strong Biomarker [332]
CDC42 OT5QBC5M Strong Biomarker [488]
CDC42EP3 OTUZ3U9Z Strong Biomarker [489]
CDCA5 OTZLCQ5U Strong Altered Expression [490]
CDCA7 OT12HDZY Strong Biomarker [491]
CDCP1 OTD7RRWK Strong Altered Expression [492]
CDH23 OTOJGQ7S Strong Altered Expression [493]
CDK14 OT385ZH1 Strong Altered Expression [494]
CDKL3 OTJ0TQ9T Strong Altered Expression [495]
CDR2 OTD3ZJST Strong Genetic Variation [496]
CDX4 OTD1SQKM Strong Biomarker [250]
CEP126 OTUMFEME Strong Biomarker [497]
CEP55 OTGSG2PA Strong Biomarker [498]
CFL1 OTT6D5MH Strong Biomarker [343]
CHAF1A OTXSSY4H Strong Biomarker [177]
CHD1L OT7CZK7C Strong Biomarker [499]
CHRNA6 OTT6W86V Strong Genetic Variation [500]
CHRNB3 OTE5XENW Strong Genetic Variation [500]
CKS1B OTNUPLUJ Strong Altered Expression [501]
CKS2 OTPTMHIV Strong Altered Expression [502]
CLDN1 OT27KV99 Strong Biomarker [503]
CLDN7 OTNE0XHQ Strong Biomarker [504]
CLTA OTLHOXMQ Strong Biomarker [505]
CMTM3 OTS75IGC Strong Altered Expression [506]
CNMD OTHND8EL Strong Altered Expression [507]
CNPY2 OTGY8ESX Strong Genetic Variation [508]
COL11A1 OTB0DRMS Strong Altered Expression [509]
COLQ OT4BHUGQ Strong Biomarker [510]
COX5A OTP0961M Strong Biomarker [511]
CPNE5 OTU882I6 Strong Altered Expression [512]
CPOX OTIAY121 Strong Biomarker [511]
CPT1A OTI862QH Strong Altered Expression [513]
CRABP1 OTISDG5X Strong Biomarker [514]
CRABP2 OTY01V9G Strong Biomarker [515]
CRCT1 OTPYME8V Strong Biomarker [516]
CREM OTJIJ5AL Strong Altered Expression [517]
CRIP2 OTVVJSYX Strong Biomarker [518]
CRISP1 OTDI4B55 Strong Genetic Variation [205]
CRISP2 OT8HLTV5 Strong Altered Expression [519]
CRISPLD2 OTVSFHTL Strong Posttranslational Modification [520]
CRNN OTAORBR4 Strong Biomarker [521]
CSRP1 OTUS7RM2 Strong Biomarker [518]
CST1 OTE4I83Q Strong Altered Expression [522]
CSTA OT1K68KE Strong Altered Expression [523]
CTAG1B OTIQGW6U Strong Biomarker [40]
CTAG2 OT8HISP4 Strong Altered Expression [524]
CTBP2 OTGZGT87 Strong Biomarker [525]
CTHRC1 OTV88X2G Strong Altered Expression [219]
CTTN OTJRG4ES Strong Altered Expression [143]
CUL4A OTTBV70J Strong Altered Expression [526]
CUL4B OT2QX4DO Strong Biomarker [527]
CUZD1 OTDQJVZ8 Strong Biomarker [179]
CXCL3 OTSL94KH Strong Biomarker [528]
DAB2IP OTF456VC Strong Altered Expression [424]
DACT1 OT19Z704 Strong Altered Expression [529]
DACT2 OTNLCC0K Strong Altered Expression [529]
DAP OT5YLL7E Strong Biomarker [530]
DCAF15 OTWBXZ0E Strong Biomarker [531]
DCDC1 OTQEHINP Strong Biomarker [436]
DCUN1D1 OT8UJLZU Strong Biomarker [532]
DDX20 OT6G8YF3 Strong Genetic Variation [533]
DDX46 OTB2X9TO Strong Altered Expression [534]
DEFB104A OTLQZR6K Strong Biomarker [110]
DENND2D OTXEFJWM Strong Altered Expression [535]
DERL1 OTJUS74N Strong Altered Expression [536]
DHDH OTKA2AL6 Strong Altered Expression [537]
DHRS2 OTFHWIY8 Strong Altered Expression [538]
DIRAS1 OT07F6PE Strong Biomarker [539]
DLX6 OT0FIJHY Strong Altered Expression [540]
DMRT2 OTA39QNR Strong Biomarker [478]
DNAH11 OT6IYFVV Strong Genetic Variation [541]
DNAH9 OTI2QIZQ Strong Biomarker [542]
DOK7 OTR2V7HO Strong Posttranslational Modification [543]
DRG1 OTIFYMI3 Strong Biomarker [544]
DROSHA OTCE68KZ Strong Altered Expression [545]
DSG2 OTJPB2TO Strong Biomarker [349]
DSP OTB2MOP8 Strong Biomarker [349]
DUSP6 OT4H6RKW Strong Altered Expression [546]
DVL2 OTMNYNCM Strong Biomarker [547]
DVL3 OTPRROHJ Strong Biomarker [548]
E2F5 OT1XWING Strong Altered Expression [549]
E2F8 OTQKZGFP Strong Altered Expression [550]
ECM1 OT1K65VW Strong Altered Expression [551]
EFNA1 OTU2NUA2 Strong Biomarker [552]
EHD2 OTTX391J Strong Altered Expression [553]
EHF OTY6TPWD Strong Altered Expression [554]
EI24 OTD4NOYS Strong Biomarker [555]
EIF3B OTF67VPH Strong Biomarker [556]
EIF3E OTI0WG98 Strong Altered Expression [557]
ELK1 OTH9MXD6 Strong Altered Expression [558]
EPB41L3 OTS6CHG2 Strong Biomarker [559]
EPC2 OTTG0W9R Strong Biomarker [560]
ERAS OT528IZO Strong Genetic Variation [561]
ERCC1 OTNPYQHI Strong Altered Expression [562]
ERCC2 OT1C8HQ4 Strong Genetic Variation [563]
ERCC3 OTVAW3P1 Strong Altered Expression [564]
ESCO1 OTZ9P12A Strong Biomarker [40]
ESD OTUSIBPS Strong Biomarker [565]
ESPN OT7Z6LX2 Strong Biomarker [566]
EVX1 OT4A84VD Strong Altered Expression [567]
EYA4 OTINGR3Z Strong Biomarker [568]
FAM135B OTCSYBI7 Strong Biomarker [444]
FAM3B OTC2S91N Strong Biomarker [569]
FAM3C OTBR6U9G Strong Altered Expression [570]
FAM83F OTGGJRO7 Strong Altered Expression [571]
FBXO31 OTF96IC2 Strong Biomarker [572]
FBXO32 OTUE978R Strong Biomarker [573]
FBXO4 OT6VYX67 Strong Biomarker [574]
FBXW4 OTEGSZOX Strong Altered Expression [423]
FEN1 OT6QGG7O Strong Genetic Variation [575]
FGF12 OTBM9QIO Strong Altered Expression [576]
FGF3 OT9PK2SI Strong Biomarker [577]
FGF5 OTQXGHBY Strong Posttranslational Modification [578]
FGFRL1 OT8HZ3ZL Strong Biomarker [579]
FHL5 OT6C00Z1 Strong Genetic Variation [309]
FLII OT7G9JG6 Strong Biomarker [580]
FLNC OT3F8J6Y Strong Biomarker [581]
FMNL3 OTRP8R4W Strong Altered Expression [582]
FNDC3B OTBILGDR Strong Biomarker [583]
FOXD2 OTAF63YV Strong Altered Expression [584]
FOXF2 OTV20NGX Strong Biomarker [585]
FOXK2 OTFXDZ3R Strong Biomarker [586]
FSD1 OT8P6PT3 Strong Biomarker [587]
FSD1L OTBQ48RF Strong Biomarker [587]
FSTL1 OT6KEZUD Strong Biomarker [588]
FUBP1 OT77SC9N Strong Altered Expression [589]
FXYD3 OT9PPRHE Strong Altered Expression [590]
FZD6 OTBCPII8 Strong Biomarker [591]
GADD45A OTDRV63V Strong Biomarker [592]
GADL1 OTJM4A0R Strong Biomarker [447]
GALNT14 OT9BSDDQ Strong Genetic Variation [593]
GALNT7 OTUJSCAO Strong Altered Expression [594]
GBE1 OTK2N05B Strong Genetic Variation [595]
GCA OTAJ7ZHG Strong Genetic Variation [596]
GCNT2 OTRUIMC4 Strong Biomarker [597]
GEMIN4 OTX7402E Strong Genetic Variation [533]
GNL3 OTILGYO4 Strong Altered Expression [598]
GOLGA7B OT6VAFR8 Strong Biomarker [599]
GOLM1 OTOZSV6O Strong Biomarker [600]
GOLPH3 OTDLGYM3 Strong Biomarker [601]
GORASP1 OTQS91S7 Strong Altered Expression [339]
GPC1 OTQKRSSV Strong Biomarker [602]
GPD2 OTV232Y7 Strong Genetic Variation [143]
GPRC5A OTPOCWR7 Strong Biomarker [603]
GPRC5C OT45AJT3 Strong Altered Expression [148]
GPSM1 OTA0SJBG Strong Altered Expression [604]
GPT2 OTS5VF7N Strong Altered Expression [605]
GPX3 OT6PK94R Strong Altered Expression [606]
GRB7 OTF8Y9XY Strong Biomarker [607]
GRHL1 OTZ4MNEW Strong Biomarker [608]
GRP OT8JDFNI Strong Biomarker [609]
GSTK1 OTDNGWAF Strong Genetic Variation [378]
GTF2B OTAH5NSO Strong Altered Expression [610]
H2AC12 OTLXVB97 Strong Altered Expression [127]
H4C1 OTB71W46 Strong Biomarker [265]
HAS3 OTPM8IL8 Strong Biomarker [611]
HAT1 OT307KEN Strong Biomarker [612]
HECTD3 OTTGP4OK Strong Altered Expression [613]
HELQ OTL1STJT Strong Genetic Variation [614]
HEY2 OTU4J3ZI Strong Altered Expression [615]
HIC1 OTI9TWY4 Strong Altered Expression [616]
HLA-E OTX1CTFB Strong Biomarker [617]
HLA-F OT76CM19 Strong Altered Expression [618]
HLTF OTRX2OSF Strong Posttranslational Modification [619]
HMGN5 OTUUAHVQ Strong Biomarker [620]
HNRNPC OT47AK4C Strong Biomarker [621]
HNRNPD OT5UO1FA Strong Altered Expression [142]
HNRNPH1 OTFRWOLM Strong Altered Expression [622]
HOOK2 OTPO4NQV Strong Biomarker [531]
HOPX OTBSR6C9 Strong Altered Expression [623]
HOXB2 OTTD6HMV Strong Biomarker [624]
HOXB7 OTC7WYU8 Strong Biomarker [625]
HOXC13 OT52AVNA Strong Biomarker [626]
HOXC6 OTBCRAZV Strong Biomarker [627]
HOXC8 OTJUYU8J Strong Altered Expression [625]
HOXD10 OT0NOWU2 Strong Altered Expression [628]
HSPA2 OTSDET7B Strong Altered Expression [629]
HSPB2 OTS01646 Strong Altered Expression [630]
HSPH1 OTVRR73T Strong Biomarker [631]
IBSP OT29944Y Strong Biomarker [632]
IFITM1 OTECO1G8 Strong Biomarker [633]
IFITM3 OT2QP8D3 Strong Biomarker [634]
IFNA17 OTHXRYG3 Strong Biomarker [635]
IGBP1 OTTHH4YE Strong Posttranslational Modification [530]
IGF2BP3 OTB97VIK Strong Altered Expression [171]
IKBKE OT5VYOSM Strong Altered Expression [636]
IL3 OT0CQ35N Strong Genetic Variation [637]
ILF2 OTWWVM9X Strong Altered Expression [638]
ILF3 OTKMZ5K5 Strong Biomarker [639]
ING1 OTEZBRKW Strong Altered Expression [640]
ING5 OTRNNSFM Strong Biomarker [641]
INTS2 OT2N5TCK Strong Biomarker [577]
INTS6 OT6GDV46 Strong Genetic Variation [642]
IQGAP1 OTZRWTGA Strong Biomarker [643]
IRF9 OTK4MYQJ Strong Altered Expression [644]
IST1 OTSFEZ2O Strong Altered Expression [645]
ITGA7 OTTBTAYW Strong Biomarker [646]
ITGB4 OT28UK84 Strong Biomarker [647]
IVNS1ABP OTYHL4I7 Strong Altered Expression [648]
JAKMIP2 OT2H3MRD Strong Posttranslational Modification [623]
KCNH4 OTHJ8WTU Strong Altered Expression [558]
KCNH8 OT3I5FLB Strong Altered Expression [558]
KCTD12 OTPYKT4Z Strong Biomarker [649]
KDM6A OTZM3MJJ Strong Biomarker [650]
KHSRP OTDHZARB Strong Altered Expression [27]
KIFC1 OTNQDS00 Strong Altered Expression [651]
KLF10 OT4F4UGS Strong Biomarker [652]
KLF15 OTGMQMVR Strong Biomarker [652]
KLF9 OTBFEJRQ Strong Biomarker [653]
KLHL1 OTAX6SAD Strong Altered Expression [47]
KLK11 OT5PKX7Y Strong Biomarker [654]
KLK13 OT8LOD2U Strong Altered Expression [655]
KMT2B OTMMAZQX Strong Altered Expression [304]
KMT2C OTC59BCO Strong Biomarker [656]
KNTC1 OTI2OOFN Strong Altered Expression [657]
KPNA2 OTU7FOE6 Strong Biomarker [658]
KRT13 OTTYSKGX Strong Biomarker [659]
KRT14 OTUVZ1DW Strong Biomarker [660]
KRT18 OTVLQFIP Strong Biomarker [661]
KRT5 OTVGI9HT Strong Biomarker [662]
LAMA1 OTQZMP86 Strong Altered Expression [663]
LAMP3 OTN0XL3W Strong Biomarker [486]
LAMTOR5 OTER0U8L Strong Altered Expression [664]
LAT OTZC1XZ1 Strong Biomarker [665]
LBX2 OTGWRSI2 Strong Altered Expression [621]
LEF1 OTWS5I5H Strong Altered Expression [666]
LETM1 OT8N4MRU Strong Altered Expression [667]
LETM2 OTCYGL4F Strong Biomarker [491]
LETMD1 OTZTZ4RD Strong Biomarker [461]
LGALS3BP OT9AGQKH Strong Biomarker [668]
LGALS9 OT7MF91K Strong Biomarker [669]
LGI1 OTPS77HO Strong Biomarker [670]
LIG3 OT48SKET Strong Genetic Variation [671]
LLGL1 OTAIQSXZ Strong Biomarker [672]
LMOD1 OTZ2MEMG Strong Biomarker [176]
LOXL4 OT6XY2JL Strong Biomarker [306]
LRATD2 OTEZBUUL Strong Biomarker [673]
LRFN2 OTI2QPM2 Strong Genetic Variation [541]
LRG1 OTLD0KWA Strong Biomarker [674]
LRP1B OT4YZG2N Strong Posttranslational Modification [675]
LRRC8A OT23OE7H Strong Biomarker [676]
LSR OTR8Y32X Strong Altered Expression [677]
LTBP2 OTS88GSD Strong Biomarker [678]
LTBP3 OTME98V7 Strong Biomarker [678]
LYPD5 OTGP7UKA Strong Altered Expression [206]
LZTS1 OTXXL864 Strong Biomarker [679]
MACC1 OTV3DLX0 Strong Biomarker [680]
MAD2L2 OT24ZO59 Strong Altered Expression [681]
MADD OTUFYVGG Strong Genetic Variation [535]
MAGEB6 OTOTV1FU Strong Biomarker [682]
MAGED1 OT6EOLFC Strong Biomarker [683]
MAGED4B OTO37U7W Strong Biomarker [441]
MAGI2 OTXDDKZS Strong Biomarker [424]
MAPK13 OT0W9GE7 Strong Biomarker [576]
MARCHF8 OTH7PNN2 Strong Altered Expression [684]
MARCHF9 OTWF84QT Strong Biomarker [685]
MASP1 OTWWCNZP Strong Altered Expression [686]
MCM10 OTV0O3JN Strong Altered Expression [687]
MCM4 OT19PNNG Strong Biomarker [591]
MCRS1 OT8K2X8P Strong Biomarker [688]
MCTS1 OT7SAOJP Strong Biomarker [689]
MED15 OT0D0JVD Strong Posttranslational Modification [690]
MED23 OTKZQT0R Strong Biomarker [691]
MFN1 OTCBXQZF Strong Biomarker [692]
MIB1 OT5C404P Strong Biomarker [693]
MICB OTS2DVDW Strong Altered Expression [694]
MINDY4 OTBZ2SZB Strong Biomarker [695]
MISP OTRZDX0N Strong Biomarker [652]
MLST8 OT8DNJSD Strong Genetic Variation [696]
MLXIP OT30UNI7 Strong Biomarker [697]
MMP23B OT2OR6TS Strong Altered Expression [154]
MMP26 OT9O89KU Strong Altered Expression [698]
MOAP1 OTVF3LUG Strong Altered Expression [686]
MPRIP OT5FV5NS Strong Altered Expression [699]
MRPL21 OT1BSWWH Strong Biomarker [76]
MT1G OTAV1OCR Strong Posttranslational Modification [700]
MT3 OTVCZ7HI Strong Posttranslational Modification [701]
MTHFD1L OTV01EFP Strong Altered Expression [702]
MTSS1 OT5DTDO2 Strong Biomarker [703]
MUC13 OTWKS9MF Strong Altered Expression [704]
MUCL1 OT9QUFL3 Strong Altered Expression [705]
MYBL2 OTZ3JX8Q Strong Altered Expression [706]
MYCL OT1MFQ5U Strong Biomarker [707]
MYEOV OTDC7UHL Strong Biomarker [708]
MYL4 OTURFCSE Strong Biomarker [499]
MYL9 OT6B22JB Strong Altered Expression [709]
MYLIP OTL0PFGV Strong Biomarker [697]
MYO1B OTGZUJ0I Strong Biomarker [538]
NAA25 OTS3QVF1 Strong Genetic Variation [710]
NAA35 OTHVXAXC Strong Biomarker [711]
NABP1 OTFTNFHW Strong Posttranslational Modification [198]
NANOG OTUEY1FM Strong Biomarker [29]
NCR3LG1 OT15YWU7 Strong Altered Expression [712]
NDC80 OTS7D306 Strong Biomarker [713]
NDP OTGDJ4US Strong Biomarker [714]
NDRG2 OT5L6KD7 Strong Altered Expression [715]
NECTIN2 OTIE0W6O Strong Altered Expression [716]
NEFH OTMSCW5I Strong Biomarker [717]
NEIL1 OTHBU5DJ Strong Genetic Variation [718]
NELFA OT7O6E84 Strong Altered Expression [719]
NEO1 OTGJ1997 Strong Altered Expression [720]
NFATC2 OTK5T6HZ Strong Biomarker [721]
NFIA OTDHQ9CG Strong Altered Expression [722]
NFIB OTX94PD0 Strong Biomarker [722]
NFIX OT1DPZAE Strong Altered Expression [723]
NFYC OTZVVEV7 Strong Genetic Variation [724]
NHEJ1 OTYOO05J Strong Altered Expression [725]
NID2 OTHC33FF Strong Altered Expression [726]
NKX2-8 OT6Q3DJ0 Strong Biomarker [727]
NONO OTN36Q6U Strong Biomarker [728]
NR2C2 OTDZWVOJ Strong Altered Expression [729]
NR2F1 OTGWZWYL Strong Altered Expression [730]
NRDC OTWBBCXO Strong Altered Expression [731]
NRIP1 OTIZOJQV Strong Biomarker [732]
NSG1 OTRIMA50 Strong Biomarker [733]
NSUN2 OTZCNM33 Strong Biomarker [458]
NUDT1 OTZSES3W Strong Altered Expression [734]
NUMB OTMB586Q Strong Altered Expression [735]
NUP98 OTNT12G2 Strong Altered Expression [432]
NUSAP1 OT85HIJ5 Strong Altered Expression [736]
OPCML OT93PQ6Y Strong Altered Expression [45]
OPN1LW OTFNUZ7O Strong Biomarker [121]
OPRPN OT6K1ZD6 Strong Altered Expression [273]
OTUB1 OT8WWM9O Strong Altered Expression [737]
PAG1 OTFOJUIQ Strong Biomarker [121]
PAQR3 OTTKJ9Y4 Strong Biomarker [738]
PARP4 OTXBK59G Strong Biomarker [739]
PAX1 OT0Y3MIM Strong Biomarker [740]
PAX9 OT25J0F7 Strong Biomarker [741]
PCBP2 OTXCN9CG Strong Altered Expression [742]
PCBP4 OTDLL4NB Strong Biomarker [121]
PCDH17 OTRK0M05 Strong Posttranslational Modification [743]
PCLAF OTMVIOUU Strong Biomarker [744]
PCLO OTXJZZ98 Strong Biomarker [745]
PDC OT1UUVYY Strong Genetic Variation [640]
PDCD6IP OTS8T6A7 Strong Biomarker [424]
PDE4DIP OTS15WNF Strong Biomarker [746]
PDHA1 OTGEU8IK Strong Altered Expression [747]
PDLIM2 OTEURRPD Strong Altered Expression [748]
PDLIM4 OT23LZYY Strong Biomarker [518]
PDLIM5 OTLQVV22 Strong Biomarker [749]
PDPN OTBUV19I Strong Biomarker [750]
PDS5A OT34P56Z Strong Biomarker [751]
PELP1 OTVXQNOT Strong Biomarker [752]
PEX6 OTFAK5EF Strong Genetic Variation [753]
PHB2 OTCAX3AW Strong Altered Expression [754]
PHF2 OTJCIQR2 Strong Altered Expression [755]
PHLDA3 OTXFUDO2 Strong Altered Expression [756]
PHLDB2 OTDKMB2G Strong Altered Expression [757]
PHLPP1 OTIFXW8D Strong Altered Expression [758]
PHLPP2 OTXB1OUI Strong Altered Expression [759]
PIK3C2B OTY2PROB Strong Altered Expression [760]
PIK3R2 OTZSUQK5 Strong Biomarker [761]
PIK3R3 OTXGJ8N1 Strong Biomarker [762]
PINK1 OT50NR57 Strong Altered Expression [763]
PITX1 OTA0UN4C Strong Biomarker [764]
PITX2 OTWMXAOY Strong Biomarker [765]
PLAAT1 OTM3M6P4 Strong Genetic Variation [766]
PLCD1 OT6WFVXZ Strong Biomarker [767]
PLCL1 OTJL2C79 Strong Genetic Variation [768]
PLEK OTB73XXA Strong Altered Expression [759]
PLEKHA2 OTY2AP6T Strong Biomarker [769]
PLRG1 OTIVZ5LL Strong Altered Expression [273]
PLXNA1 OTN0BING Strong Altered Expression [770]
PMAIP1 OTXEE550 Strong Biomarker [335]
POLD2 OTBNASP6 Strong Genetic Variation [389]
POLI OTBA4DCE Strong Biomarker [771]
POLQ OTBHK0E6 Strong Genetic Variation [221]
POLR2E OTH5IL2A Strong Genetic Variation [772]
POTEG OTGGSJW3 Strong Altered Expression [773]
POTEM OT7L2HGH Strong Genetic Variation [309]
POU3F3 OT6BBXPD Strong Biomarker [774]
POU5F1 OTDHHN7O Strong Biomarker [145]
PPIG OTZ8BTTM Strong Genetic Variation [775]
PPL OTTM4WDO Strong Biomarker [776]
PPP1R18 OT0JVGOZ Strong Biomarker [652]
PRAF2 OT1QN4LV Strong Biomarker [777]
PRB2 OTAD4JZ0 Strong Altered Expression [778]
PRDM2 OT8L7CGX Strong Biomarker [779]
PRDX1 OTZ3BEC4 Strong Biomarker [780]
PRDX6 OTS8KC8A Strong Altered Expression [781]
PRIMA1 OT9ITT3P Strong Altered Expression [782]
PRM3 OT6574BF Strong Genetic Variation [384]
PRR11 OT2JJ08Z Strong Biomarker [783]
PRSS2 OTOMVUWL Strong Altered Expression [210]
PRSS3 OTN3S5YB Strong Posttranslational Modification [784]
PRSS55 OTXXWI5Y Strong Altered Expression [519]
PSMD14 OTJWHMZ5 Strong Altered Expression [785]
PSMD7 OT7PZZ4K Strong Biomarker [786]
PSME2 OTYPP33T Strong Biomarker [307]
PTMA OT2W4T1M Strong Biomarker [176]
PTOV1 OT94WT5X Strong Altered Expression [787]
PTPN12 OT5WA666 Strong Altered Expression [788]
PTPN9 OTNAR1I2 Strong Altered Expression [789]
PTPRD OTZPJ3GX Strong Biomarker [117]
PTPRO OTFLKWOY Strong Biomarker [790]
PTPRT OTV5TXNN Strong Genetic Variation [791]
PTRH2 OTBU39Q1 Strong Altered Expression [792]
PTTG1 OTIMYS4W Strong Altered Expression [793]
PTTG2 OTXGZ8FV Strong Altered Expression [793]
PXN OTVMMUOF Strong Altered Expression [794]
PYCR2 OTS2HLGD Strong Biomarker [399]
PYGO2 OTZHB2OI Strong Biomarker [795]
PYROXD2 OTJIX22S Strong Genetic Variation [143]
QKI OTTAUGLB Strong Altered Expression [796]
RAB10 OT8ZN26V Strong Biomarker [797]
RAB23 OTBAKFBR Strong Altered Expression [798]
RAB25 OTW0W6NP Strong Biomarker [799]
RAB31 OTMLXQZ0 Strong Altered Expression [800]
RAB37 OTRL8IUO Strong Biomarker [519]
RAB3D OTGKRR3C Strong Biomarker [801]
RABGAP1L OT7QO47I Strong Altered Expression [802]
RAD17 OT1I93DT Strong Genetic Variation [719]
RAD18 OTQ9PLNT Strong Biomarker [803]
RAN OT2TER5M Strong Genetic Variation [533]
RAP1A OT5RH6TI Strong Biomarker [804]
RAP1B OTHEIIMM Strong Biomarker [547]
RARRES1 OTETUPP5 Strong Posttranslational Modification [690]
RASGRP3 OTEMEV3P Strong Altered Expression [805]
RASSF10 OTGB7EBG Strong Posttranslational Modification [806]
RASSF2 OT2JHDO4 Strong Altered Expression [807]
RASSF5 OT6Q41I2 Strong Biomarker [808]
RASSF6 OT25GVWY Strong Biomarker [809]
RASSF8 OTXKGIB3 Strong Biomarker [810]
RBBP7 OTLB56HX Strong Altered Expression [811]
RBM3 OTAJ7R31 Strong Altered Expression [812]
RERE OT3G4GBZ Strong Genetic Variation [205]
REV3L OT0OP8EJ Strong Altered Expression [813]
RFC2 OTJ9N6BD Strong Genetic Variation [719]
RHOC OTOLE1FT Strong Altered Expression [814]
RHOF OTPA3F8Q Strong Biomarker [815]
RIT1 OTVNOGOH Strong Biomarker [816]
RNASE1 OTKZ7CO9 Strong Biomarker [817]
RNASEH2C OTJL9ZRN Strong Altered Expression [604]
RND3 OTXMXPIH Strong Biomarker [818]
RNF113A OTR6N7HU Strong Biomarker [819]
RNF128 OTJO86CJ Strong Biomarker [820]
RNF2 OTFPLOIN Strong Altered Expression [821]
RNF8 OTRR43PZ Strong Biomarker [822]
RPN2 OTJ1SKOA Strong Altered Expression [823]
RPS6 OTT4D1LN Strong Posttranslational Modification [824]
RPTOR OT4TQZ9F Strong Genetic Variation [696]
RRAD OTW2O4GD Strong Posttranslational Modification [825]
RRAS OTBBF28C Strong Biomarker [826]
RRAS2 OT83NCEB Strong Biomarker [827]
RSRC2 OTLE0KQM Strong Biomarker [828]
RTRAF OTJ6NVMW Strong Altered Expression [829]
S100A11 OTI57KDN Strong Genetic Variation [830]
S100A14 OTVFJJ91 Strong Genetic Variation [831]
SAFB OTGRV2LW Strong Altered Expression [832]
SALL2 OTQWI68Q Strong Biomarker [833]
SALL4 OTC08PR5 Strong Biomarker [834]
SASH1 OTQA8BD4 Strong Altered Expression [835]
SATB2 OT2W80XC Strong Biomarker [836]
SBF2 OTBB8NO8 Strong Biomarker [837]
SBK1 OTCO4NEI Strong Altered Expression [838]
SBSN OT89RKJH Strong Biomarker [839]
SCAI OTAK3TMO Strong Altered Expression [840]
SCARA5 OTOVA96E Strong Altered Expression [316]
SCEL OT46SDNQ Strong Biomarker [841]
SCO2 OTJQQDRS Strong Biomarker [330]
SDR9C7 OTQY8SJ3 Strong Biomarker [217]
SEL1L OTC0FB7T Strong Biomarker [842]
SEMA3B OTCZCPMS Strong Altered Expression [843]
SEPTIN9 OT1VMRFQ Strong Biomarker [624]
SERPINB2 OT72QLZB Strong Altered Expression [844]
SERPINE2 OTYF5340 Strong Biomarker [845]
SERTAD1 OTBHKZQP Strong Altered Expression [846]
SET OTGYYQJO Strong Biomarker [847]
SFN OTLJCZ1U Strong Biomarker [343]
SFRP2 OT8GZ0CA Strong Posttranslational Modification [848]
SGTA OTKOJ3JB Strong Biomarker [849]
SHANK2 OTSQTPFQ Strong Biomarker [130]
SHOX2 OTLCZZJW Strong Biomarker [850]
SIRT4 OT5S0J23 Strong Biomarker [851]
SIX1 OT70YYWM Strong Altered Expression [852]
SKA1 OTDYJ12A Strong Altered Expression [853]
SLAMF1 OTBTT3ZQ Strong Biomarker [854]
SLC12A9 OTR7VRAK Strong Genetic Variation [88]
SLC16A4 OT1YXBKC Strong Biomarker [293]
SLC22A18 OT9C3KR4 Strong Altered Expression [832]
SMARCA2 OTSGJ8SV Strong Altered Expression [855]
SMG1 OTTS3SXE Strong Biomarker [348]
SNAI1 OTDPYAMC Strong Biomarker [737]
SORBS2 OTJSX44Y Strong Biomarker [478]
SOX1 OTVI1RAR Strong Biomarker [740]
SOX15 OTTB37I1 Strong Altered Expression [856]
SOX17 OT9H4WWE Strong Altered Expression [420]
SOX3 OT1CRCOB Strong Biomarker [857]
SOX4 OTSS40SS Strong Biomarker [858]
SPA17 OT8J7T7U Strong Altered Expression [476]
SPIN1 OT69VAOX Strong Biomarker [859]
SPINK7 OTK3VOI3 Strong Biomarker [860]
SPINT1 OT1CLR5L Strong Altered Expression [861]
SPINT2 OTQV7BKQ Strong Posttranslational Modification [862]
SPPL2A OTCVF6MM Strong Altered Expression [171]
SPRR2A OT62ZU6B Strong Altered Expression [863]
SPRR3 OTN9QJKG Strong Altered Expression [864]
SPRY4 OT2VK9N0 Strong Altered Expression [160]
SPSB3 OTHGEE2K Strong Altered Expression [865]
SRPX2 OT6A63TX Strong Biomarker [866]
SSBP2 OTYG1G80 Strong Biomarker [198]
ST13 OTNML6UP Strong Altered Expression [623]
ST6GALNAC1 OT3JQD99 Strong Altered Expression [867]
STAT2 OTO9G2RZ Strong Altered Expression [644]
STING1 OTDAP4G0 Strong Genetic Variation [32]
STIP1 OT7TXLOX Strong Biomarker [868]
STX6 OTC5F5M6 Strong Biomarker [869]
SUB1 OTK71JYU Strong Altered Expression [725]
SYCE1L OTXU44F3 Strong Altered Expression [47]
SYNJ2BP OT2Q677P Strong Biomarker [143]
SYT1 OTVTPOI6 Strong Altered Expression [339]
SYTL2 OTUIOWKL Strong Altered Expression [305]
TAB3 OT1ECMDL Strong Biomarker [870]
TAS2R13 OTSTOX5G Strong Genetic Variation [389]
TAS2R14 OTWA9CYC Strong Genetic Variation [389]
TAS2R42 OTMEJBFJ Strong Genetic Variation [389]
TAS2R46 OTK23I2G Strong Genetic Variation [389]
TAS2R50 OTPRMVZW Strong Genetic Variation [389]
TCEAL1 OTAPG2L5 Strong Altered Expression [871]
TCF21 OT393IMA Strong Altered Expression [872]
TCF7 OT1ID822 Strong Biomarker [275]
TCHP OTVDMHSY Strong Altered Expression [424]
TCN2 OT41D0L3 Strong Biomarker [128]
TCTN1 OTG5KEV8 Strong Altered Expression [873]
TENM3 OTWY13GR Strong Altered Expression [837]
TET3 OT76U3YF Strong Altered Expression [874]
TEX10 OTNTU9CB Strong Altered Expression [875]
TEX9 OTMYCDCW Strong Altered Expression [556]
TFCP2 OTA246TE Strong Altered Expression [876]
TGFB1I1 OTIK337D Strong Altered Expression [877]
TGFBI OTR443C5 Strong Altered Expression [878]
THSD1 OTKPGFHS Strong Posttranslational Modification [879]
THSD7A OT7249HH Strong Biomarker [880]
THUMPD2 OTNNGX4U Strong Altered Expression [881]
THY1 OTVONVTB Strong Altered Expression [882]
TIGAR OTR7NMRJ Strong Altered Expression [31]
TIMM8A OTDX9687 Strong Biomarker [883]
TIMP3 OTDGQAD1 Strong Biomarker [884]
TM4SF1 OTY0ECQN Strong Altered Expression [885]
TMEM176A OTOZDWXX Strong Biomarker [886]
TMPRSS11A OTB35677 Strong Genetic Variation [887]
TMPRSS11E OTO5U2TK Strong Biomarker [888]
TMPRSS4 OTCCGY2K Strong Biomarker [889]
TNFAIP2 OTRZH80H Strong Altered Expression [890]
TNFAIP8 OT1G9297 Strong Biomarker [39]
TNRC6B OTGVT0SH Strong Genetic Variation [533]
TNRC6C OTBR07PM Strong Altered Expression [469]
TNXB OTVBWAV5 Strong Biomarker [128]
TOM1L1 OT37NXR0 Strong Altered Expression [891]
TP53BP2 OTOWJ2Y4 Strong Altered Expression [892]
TP53I3 OTSCM68G Strong Biomarker [893]
TPM1 OTD73X6R Strong Altered Expression [894]
TPM4 OTN4YLYR Strong Biomarker [895]
TRAF4 OTJLRVMC Strong Altered Expression [896]
TRAP1 OTNG0L8J Strong Altered Expression [897]
TRIM16 OTLRXYOZ Strong Biomarker [809]
TRIM3 OT704FQ0 Strong Altered Expression [339]
TRIM44 OT0B1T2B Strong Altered Expression [898]
TRIP13 OTFM3TI9 Strong Altered Expression [899]
TSGA10 OTIF1O1T Strong Biomarker [900]
TSPAN15 OTNQXXIG Strong Biomarker [463]
TSPAN4 OTKFK57F Strong Altered Expression [901]
TTC17 OTQV0VWV Strong Altered Expression [902]
TTC39B OTE2ZGFB Strong Biomarker [221]
AKIP1 OT7XPG27 Definitive Biomarker [903]
AQP5 OT77GBY8 Definitive Biomarker [904]
BLVRB OTHCFN2C Definitive Biomarker [343]
C15orf48 OT85J32K Definitive Altered Expression [905]
CAPZA1 OTAXA66U Definitive Biomarker [343]
CCN4 OT69BER9 Definitive Altered Expression [906]
CDKN3 OTBE3H07 Definitive Altered Expression [907]
CENPF OT7AG0SW Definitive Biomarker [908]
CSTB OT3U0JF8 Definitive Biomarker [343]
CTNND2 OTYKE30Y Definitive Biomarker [909]
DCC OT2C1SHW Definitive Posttranslational Modification [910]
DIDO1 OT9PB547 Definitive Biomarker [834]
DLEC1 OTMKKBUW Definitive Genetic Variation [911]
ECRG4 OTHZYUXX Definitive Biomarker [912]
EFNB2 OT0DCUOM Definitive Altered Expression [352]
EMP3 OTODMJ1D Definitive Biomarker [913]
ERCC5 OTQAKFJM Definitive Biomarker [914]
FADD OTV7GFHH Definitive Biomarker [915]
FAT2 OTRGT3E8 Definitive Biomarker [916]
FAT3 OT3C6H8W Definitive Biomarker [916]
FAT4 OT7QONNV Definitive Biomarker [916]
GBP1 OTUM7RPJ Definitive Altered Expression [917]
GDI2 OTGLY3I7 Definitive Biomarker [343]
GSTM2 OTG4WT05 Definitive Genetic Variation [918]
H2BC14 OTSDZZZY Definitive Biomarker [343]
KRT4 OT24PHPM Definitive Biomarker [660]
LDHB OT9B1CT3 Definitive Altered Expression [919]
LMLN OTQF0JPY Definitive Biomarker [357]
LTO1 OTQ17ZDT Definitive Altered Expression [920]
MAP1LC3A OTPMGIU4 Definitive Altered Expression [921]
MBD4 OTWR9YXE Definitive Genetic Variation [922]
MUC20 OTYYE1GK Definitive Biomarker [923]
PAK5 OT32WQGL Definitive Altered Expression [924]
PCGF2 OTIY1J5L Definitive Biomarker [925]
PDLIM7 OTAZVODU Definitive Altered Expression [926]
PFN1 OTHTGA1H Definitive Biomarker [343]
POLM OT0SRIP4 Definitive Biomarker [927]
PPP1R1B OTSIJMQ9 Definitive Biomarker [928]
PROX1 OT68R6IO Definitive Altered Expression [929]
PSME1 OTDHLJWH Definitive Biomarker [343]
PTX3 OTPXHRKU Definitive Altered Expression [930]
RBMS3 OTFSC9MR Definitive Biomarker [931]
REPS2 OTSE3TRP Definitive Biomarker [932]
S100A1 OT1F2G4J Definitive Altered Expression [933]
S100A2 OTTGHJ1H Definitive Biomarker [934]
SMR3B OTL5HNM8 Definitive Biomarker [364]
SOX6 OTT0W0LE Definitive Altered Expression [935]
TMEFF2 OT1WZ2QO Definitive Biomarker [936]
TMPRSS13 OTMAOAP3 Definitive Biomarker [357]
TPI1 OT14KP4B Definitive Biomarker [343]
TPM2 OTA1L0P8 Definitive Biomarker [343]
------------------------------------------------------------------------------------
⏷ Show the Full List of 736 DOT(s)

References

1 Cisplatin FDA Label
2 Fluorouracil FDA Label
3 ClinicalTrials.gov (NCT03829969) A Phase III, Randomized, Double-blind, Placebo-controlled, Multi-center Study to Compare Toripalimab Injection (JS001) Combined With Standard Chemotherapy Versus Placebo Combined With Standard Chemotherapy in Treatment of Advanced or Metastatic Esophageal Squamous Cell Cancer (ESCC) Without Previous Systemic Chemotherapy. U.S.National Institutes of Health.
4 Development of Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Signaling Pathway.J Med Chem. 2019 Feb 28;62(4):1715-1730.
5 ClinicalTrials.gov (NCT03785496) Study to Evaluate Efficacy of PDR001 in Patients With Squamous Cell Carcinoma of the Esophagus. U.S. National Institutes of Health.
6 ClinicalTrials.gov (NCT04785820) A Study of RO7121661 and RO7247669 Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus. U.S. National Institutes of Health.
7 Emerging therapies targeting the ubiquitin proteasome system in cancer. J Clin Invest. 2014 Jan;124(1):6-12.
8 Deguelin, an Aurora B Kinase Inhibitor, Exhibits Potent Anti-Tumor Effect in Human Esophageal Squamous Cell Carcinoma. EBioMedicine. 2017 Dec;26:100-111.
9 Chlorogenic acid inhibits esophageal squamous cell carcinoma growth in vitro and in vivo by downregulating the expression of BMI1 and SOX2.Biomed Pharmacother. 2020 Jan;121:109602. doi: 10.1016/j.biopha.2019.109602. Epub 2019 Nov 7.
10 Expression of proteins associated with epithelial-mesenchymal transition in esophageal squamous cell carcinoma.Oncol Lett. 2018 Mar;15(3):3042-3048. doi: 10.3892/ol.2017.7701. Epub 2017 Dec 28.
11 Positive correlation of cysteine-rich 61 and target genes of Wnt/-catenin pathway in esophageal squamous cell carcinoma.J Cancer Res Ther. 2016 Oct;12(Supplement):19-22. doi: 10.4103/0973-1482.191622.
12 Clinical use of tumor biomarkers in prediction for prognosis and chemotherapeutic effect in esophageal squamous cell carcinoma.BMC Cancer. 2019 May 31;19(1):526. doi: 10.1186/s12885-019-5755-5.
13 Optimized Cutoff Value of Serum Squamous Cell Carcinoma Antigen Concentration Accurately Predicts Recurrence After Curative Resection of Squamous Cell Carcinoma of the Esophagus.Ann Surg Oncol. 2020 Apr;27(4):1233-1240. doi: 10.1245/s10434-019-07977-6. Epub 2019 Oct 24.
14 LncRNA CASC9 promotes esophageal squamous cell carcinoma metastasis through upregulating LAMC2 expression by interacting with the CREB-binding protein.Cell Death Differ. 2018 Nov;25(11):1980-1995. doi: 10.1038/s41418-018-0084-9. Epub 2018 Mar 6.
15 Prognostic significance of platelet C-reactive protein multiplier in patients with esophageal squamous cell carcinoma.Surg Today. 2020 Feb;50(2):185-192. doi: 10.1007/s00595-019-01865-y. Epub 2019 Aug 30.
16 Induction of PD-L1 expression by epidermal growth factor receptor-mediated signaling in esophageal squamous cell carcinoma.Onco Targets Ther. 2017 Feb 13;10:763-771. doi: 10.2147/OTT.S118982. eCollection 2017.
17 Endoglin promoter hypermethylation identifies a field defect in human primary esophageal cancer.Cancer. 2013 Oct 15;119(20):3604-9. doi: 10.1002/cncr.28276. Epub 2013 Jul 24.
18 miR-133b inhibits cell proliferation, migration and invasion of esophageal squamous cell carcinoma by targeting EGFR.Biomed Pharmacother. 2019 Mar;111:476-484. doi: 10.1016/j.biopha.2018.12.057. Epub 2018 Dec 27.
19 LncRNA Erbb4-IR promotes esophageal squamous cell carcinoma (ESCC) by downregulating miR-145.J Cell Biochem. 2019 Oct;120(10):17566-17572. doi: 10.1002/jcb.29023. Epub 2019 May 22.
20 Long noncoding RNA linc-UBC1 promotes tumor invasion and metastasis by regulating EZH2 and repressing E-cadherin in esophageal squamous cell carcinoma.J BUON. 2018 Jan-Feb;23(1):157-162.
21 Correlation between high FBXW7 expression in pretreatment biopsy specimens and good response to chemoradiation therapy in patients with locally advanced esophageal cancer: A retrospective study.J Surg Oncol. 2018 Jul;118(1):101-108. doi: 10.1002/jso.25127. Epub 2018 Aug 11.
22 Poor prognostic impact of FGF4 amplification in patients with esophageal squamous cell carcinoma.Hum Pathol. 2018 Oct;80:210-218. doi: 10.1016/j.humpath.2018.06.009. Epub 2018 Jun 22.
23 Fra-1 Regulates theExpression of HMGA1,Which is Associated with a Poor Prognosis in Human Esophageal Squamous Cell Carcinoma.Ann Surg Oncol. 2017 Oct;24(11):3446-3455. doi: 10.1245/s10434-016-5666-5. Epub 2016 Nov 23.
24 Overexpression of long noncoding RNA LINC01419 in esophageal squamous cell carcinoma and its relation to the sensitivity to 5-fluorouracil by mediating GSTP1 methylation.Ther Adv Med Oncol. 2019 Apr 12;11:1758835919838958. doi: 10.1177/1758835919838958. eCollection 2019.
25 Knockdown of HOXA5 inhibits the tumorigenesis in esophageal squamous cell cancer. Biomed Pharmacother. 2017 Feb;86:149-154.
26 Genetic polymorphisms in the 9p21 region associated with risk of multiple cancers.Carcinogenesis. 2014 Dec;35(12):2698-705. doi: 10.1093/carcin/bgu203. Epub 2014 Sep 19.
27 Flow Cytometric Detection of Circulating Tumor Cells Using a Candidate Stem Cell Marker, p75 Neurotrophin Receptor (p75NTR).Methods Mol Biol. 2017;1634:211-217. doi: 10.1007/978-1-4939-7144-2_18.
28 LSD1 regulates Notch and PI3K/Akt/mTOR pathways through binding the promoter regions of Notch target genes in esophageal squamous cell carcinoma.Onco Targets Ther. 2019 Jul 2;12:5215-5225. doi: 10.2147/OTT.S207238. eCollection 2019.
29 A three-gene signature and clinical outcome in esophageal squamous cell carcinoma.Int J Cancer. 2015 Mar 15;136(6):E569-77. doi: 10.1002/ijc.29211. Epub 2014 Sep 24.
30 Down-regulated miR-26a promotes proliferation, migration, and invasion via negative regulation of MTDH in esophageal squamous cell carcinoma.FASEB J. 2017 May;31(5):2114-2122. doi: 10.1096/fj.201601237. Epub 2017 Feb 7.
31 Inhibition of MUC1-C regulates metabolism by AKT pathway in esophageal squamous cell carcinoma.J Cell Physiol. 2019 Jul;234(7):12019-12028. doi: 10.1002/jcp.27863. Epub 2018 Dec 6.
32 Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations.Nat Genet. 2014 Sep;46(9):1001-1006. doi: 10.1038/ng.3064. Epub 2014 Aug 17.
33 CACNA2D3 Enhances the Chemosensitivity of Esophageal Squamous Cell Carcinoma to Cisplatin via Inducing Ca(2+)-Mediated Apoptosis and Suppressing PI3K/Akt Pathways.Front Oncol. 2019 Apr 2;9:185. doi: 10.3389/fonc.2019.00185. eCollection 2019.
34 Sequestosome 1 protects esophageal squamous carcinoma cells from apoptosis via stabilizing SKP2 under serum starvation condition.Oncogene. 2018 Jun;37(24):3260-3274. doi: 10.1038/s41388-018-0217-0. Epub 2018 Mar 19.
35 Solute Carrier Family 39 Member 6 Gene Promotes Aggressiveness of Esophageal Carcinoma Cells by Increasing Intracellular Levels of Zinc, Activating Phosphatidylinositol 3-Kinase Signaling, and Up-regulating Genes That RegulateMetastasis.Gastroenterology. 2017 Jun;152(8):1985-1997.e12. doi: 10.1053/j.gastro.2017.02.006. Epub 2017 Feb 14.
36 Network analyses elucidate the role of SMYD3 in esophageal squamous cell carcinoma.FEBS Open Bio. 2017 Jul 3;7(8):1111-1125. doi: 10.1002/2211-5463.12251. eCollection 2017 Aug.
37 TNFmediated upregulation of SOD? contributes to cell proliferation and cisplatin resistance in esophageal squamous cell carcinoma.Oncol Rep. 2019 Oct;42(4):1497-1506. doi: 10.3892/or.2019.7252. Epub 2019 Jul 26.
38 Novel signal transducer and activator of transcription 1 mutation disrupts small ubiquitin-related modifier conjugation causing gain of function.J Allergy Clin Immunol. 2018 May;141(5):1844-1853.e2. doi: 10.1016/j.jaci.2017.07.027. Epub 2017 Aug 30.
39 Possible biomarkers for predicting lymph node metastasis of esophageal squamous cell carcinoma: a review.J Int Med Res. 2019 Feb;47(2):544-556. doi: 10.1177/0300060518819606. Epub 2019 Jan 7.
40 Linkage between EMT and stemness state through molecular association between TWIST1 and NY-ESO1 in esophageal squamouscell carcinoma.Biochimie. 2019 Aug;163:84-93. doi: 10.1016/j.biochi.2019.05.016. Epub 2019 May 31.
41 Overexpression of VEGF-C and MMP-9 predicts poor prognosis in Kazakh patients with esophageal squamous cell carcinoma.PeerJ. 2019 Dec 3;7:e8182. doi: 10.7717/peerj.8182. eCollection 2019.
42 Chemokines and their receptors as biomarkers in esophageal cancer.Esophagus. 2020 Apr;17(2):113-121. doi: 10.1007/s10388-019-00706-8. Epub 2019 Nov 26.
43 Combined prognostic value of the cancer stem cell markers CD47 and CD133 in esophageal squamous cell carcinoma.Cancer Med. 2019 Mar;8(3):1315-1325. doi: 10.1002/cam4.1894. Epub 2019 Feb 11.
44 Circular RNA ciRS-7 triggers the migration and invasion of esophageal squamous cell carcinoma via miR-7/KLF4 and NF-B signals.Cancer Biol Ther. 2019;20(1):73-80. doi: 10.1080/15384047.2018.1507254. Epub 2018 Sep 12.
45 Epigenetic deregulations of Wnt/-catenin and transforming growth factor beta-Smad pathways in esophageal cancer: Outcome of DNA methylation.J Cancer Res Ther. 2019 Jan-Mar;15(1):192-203. doi: 10.4103/jcrt.JCRT_634_17.
46 PTP1B up-regulates EGFR expression by dephosphorylating MYH9 at Y1408 to promote cell migration and invasion in esophageal squamous cell carcinoma.Biochem Biophys Res Commun. 2020 Jan 29;522(1):53-60. doi: 10.1016/j.bbrc.2019.10.168. Epub 2019 Nov 15.
47 Role of multidrug resistance protein 2 (MRP2) in chemoresistance and clinical outcome in oesophageal squamous cell carcinoma.Br J Cancer. 2011 Feb 15;104(4):707-13. doi: 10.1038/sj.bjc.6606071. Epub 2011 Jan 4.
48 DNMT1-microRNA126 epigenetic circuit contributes to esophageal squamous cell carcinoma growth via ADAM9-EGFR-AKT signaling.Clin Cancer Res. 2015 Feb 15;21(4):854-63. doi: 10.1158/1078-0432.CCR-14-1740. Epub 2014 Dec 15.
49 Genetic variant repressing ADH1A expression confers susceptibility to esophageal squamous-cell carcinoma.Cancer Lett. 2018 May 1;421:43-50. doi: 10.1016/j.canlet.2017.12.020. Epub 2017 Dec 15.
50 Replication study of ESCC susceptibility genetic polymorphisms locating in the ADH1B-ADH1C-ADH7 cluster identified by GWAS.PLoS One. 2014 Apr 10;9(4):e94096. doi: 10.1371/journal.pone.0094096. eCollection 2014.
51 Acylglycerol kinase augments JAK2/STAT3 signaling in esophageal squamous cells.J Clin Invest. 2013 Jun;123(6):2576-89. doi: 10.1172/JCI68143. Epub 2013 May 8.
52 Overexpression of S-adenosylhomocysteine hydrolase (SAHH) in esophageal squamous cell carcinoma (ESCC) cell lines: effects on apoptosis, migration and adhesion of cells.Mol Biol Rep. 2014;41(4):2409-17. doi: 10.1007/s11033-014-3095-8. Epub 2014 Jan 16.
53 Circular RNA circ-PRKCI functions as a competitive endogenous RNA to regulate AKT3 expression by sponging miR-3680-3p in esophageal squamous cell carcinoma.J Cell Biochem. 2019 Jun;120(6):10021-10030. doi: 10.1002/jcb.28285. Epub 2019 Jan 18.
54 12-lipoxygenase promotes tumor progress by TGF-1-mediated epithelial to mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma.Cancer Manag Res. 2019 Sep 11;11:8303-8313. doi: 10.2147/CMAR.S212478. eCollection 2019.
55 Integrated analysis of genomic and transcriptomic profiles identified a prognostic immunohistochemistry panel for esophageal squamous cell cancer.Cancer Med. 2020 Jan;9(2):575-585. doi: 10.1002/cam4.2744. Epub 2019 Dec 2.
56 miR-196a regulates the proliferation, invasion and migration of esophageal squamous carcinoma cells by targeting ANXA1.Oncol Lett. 2019 Jun;17(6):5201-5209. doi: 10.3892/ol.2019.10186. Epub 2019 Mar 22.
57 ANXA10 induction by interaction with tumor-associated macrophages promotes the growth of esophageal squamous cell carcinoma.Pathol Int. 2019 Mar;69(3):135-147. doi: 10.1111/pin.12771. Epub 2019 Feb 13.
58 Downregulation of miR-138 sustains NF-B activation and promotes lipid raft formation in esophageal squamous cell carcinoma.Clin Cancer Res. 2013 Mar 1;19(5):1083-93. doi: 10.1158/1078-0432.CCR-12-3169. Epub 2013 Jan 14.
59 Assessment of apelin, apelin receptor, resistin, and adiponectin levels in the primary tumor and serum of patients with esophageal squamous cell carcinoma.Adv Clin Exp Med. 2019 May;28(5):671-678. doi: 10.17219/acem/94135.
60 Prognostic nomogram integrated baseline serum lipids for patients with non-esophageal squamous cell carcinoma.Ann Transl Med. 2019 Oct;7(20):548. doi: 10.21037/atm.2019.09.86.
61 Co-expression of AQP3 and AQP5 in esophageal squamous cell carcinoma correlates with aggressive tumor progression and poor prognosis.Med Oncol. 2013;30(3):636. doi: 10.1007/s12032-013-0636-2. Epub 2013 Jun 25.
62 Combined detection of IL-6 and IL-8 is beneficial to the diagnosis of early stage esophageal squamous cell cancer: a preliminary study based on the screening of serum markers using protein chips.Onco Targets Ther. 2018 Sep 12;11:5777-5787. doi: 10.2147/OTT.S171242. eCollection 2018.
63 Downregulation of AAA-domain-containing protein 2 restrains cancer stem cell properties in esophageal squamous cell carcinoma via blockade of the Hedgehog signaling pathway.Am J Physiol Cell Physiol. 2020 Jul 1;319(1):C93-C104. doi: 10.1152/ajpcell.00133.2019. Epub 2019 Nov 20.
64 FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma.Mol Oncol. 2019 May;13(5):1150-1165. doi: 10.1002/1878-0261.12474. Epub 2019 Mar 23.
65 OV6(+) cancer stem cells drive esophageal squamous cell carcinoma progression through ATG7-dependent -catenin stabilization.Cancer Lett. 2017 Apr 10;391:100-113. doi: 10.1016/j.canlet.2017.01.026. Epub 2017 Jan 25.
66 Overexpression of ATPase Na+/+ transporting alpha 1 polypeptide, ATP1A1, correlates with clinical diagnosis and progression of esophageal squamous cell carcinoma.Oncotarget. 2016 Dec 20;7(51):85244-85258. doi: 10.18632/oncotarget.13267.
67 Upregulation of STK15 in esophageal squamous cell carcinomas in a Mongolian population.Asian Pac J Cancer Prev. 2014;15(15):6021-4. doi: 10.7314/apjcp.2014.15.15.6021.
68 Reduction of AZGP1 predicts poor prognosis in esophageal squamous cell carcinoma patients in Northern China.Onco Targets Ther. 2016 Dec 20;10:85-94. doi: 10.2147/OTT.S113932. eCollection 2017.
69 Mesenchymal Stromal Cells-Derived 2-Microglobulin Promotes Epithelial-Mesenchymal Transition of Esophageal Squamous Cell Carcinoma Cells.Sci Rep. 2018 Apr 3;8(1):5422. doi: 10.1038/s41598-018-23651-5.
70 MAGE, BAGE, and GAGE gene expression in patients with esophageal squamous cell carcinoma and adenocarcinoma of the gastric cardia.Cancer. 2001 May 15;91(10):1882-8.
71 The role of DNMT1/hsa-miR-124-3p/BCAT1 pathway in regulating growth and invasion of esophageal squamous cell carcinoma.BMC Cancer. 2019 Jun 21;19(1):609. doi: 10.1186/s12885-019-5815-x.
72 High expression of biglycan is associated with poor prognosis in patients with esophageal squamous cell carcinoma.Int J Clin Exp Pathol. 2013 Oct 15;6(11):2497-505. eCollection 2013.
73 The Role of cIAP1 and XIAP in Apoptosis Induced by Tumor Necrosis Factor Alpha in Esophageal Squamous Cell Carcinoma Cells.Dig Dis Sci. 2017 Mar;62(3):652-659. doi: 10.1007/s10620-016-4430-9. Epub 2017 Jan 3.
74 Overexpression of Transmembrane Protein BST2 is Associated with Poor Survival of Patients with Esophageal, Gastric, or Colorectal Cancer.Ann Surg Oncol. 2017 Feb;24(2):594-602. doi: 10.1245/s10434-016-5100-z. Epub 2016 Feb 1.
75 Genetic polymorphisms of NAMPT related with susceptibility to esophageal squamous cell carcinoma.BMC Gastroenterol. 2015 Apr 21;15:49. doi: 10.1186/s12876-015-0282-6.
76 Identification of genomic biomarkers associated with the clinicopathological parameters and prognosis of esophageal squamous cell carcinoma.Cancer Biomark. 2015;15(6):755-61. doi: 10.3233/CBM-150517.
77 Intensity-Modulated Radiotherapy versus Three-Dimensional Conformal Radiotherapy in Definitive Chemoradiotherapy for Cervical Esophageal Squamous Cell Carcinoma: Comparison of Survival Outcomes and Toxicities.Cancer Res Treat. 2020 Jan;52(1):31-40. doi: 10.4143/crt.2018.624. Epub 2019 Apr 30.
78 The loss of CASP4 expression is associated with poor prognosis in esophageal squamous cell carcinoma.Oncol Lett. 2017 Mar;13(3):1761-1766. doi: 10.3892/ol.2017.5646. Epub 2017 Jan 25.
79 MicroRNA-375 inhibits esophageal squamous cell carcinoma proliferation through direct targeting of SP1.Exp Ther Med. 2019 Mar;17(3):1509-1516. doi: 10.3892/etm.2018.7106. Epub 2018 Dec 17.
80 MiR-219-5p suppresses cell proliferation and cell cycle progression in esophageal squamous cell carcinoma by targeting CCNA2.Cell Mol Biol Lett. 2019 Feb 5;24:4. doi: 10.1186/s11658-018-0129-6. eCollection 2019.
81 Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.Eur J Pharmacol. 2019 May 15;851:43-51. doi: 10.1016/j.ejphar.2019.02.030. Epub 2019 Feb 16.
82 Association of tumour-associated macrophages with cancer cell EMT, invasion, and metastasis of Kazakh oesophageal squamous cell cancer.Diagn Pathol. 2019 Jun 12;14(1):55. doi: 10.1186/s13000-019-0834-0.
83 Indoleamine 2,3-dioxygenase 1 and overall survival of patients diagnosed with esophageal cancer.Oncotarget. 2018 May 4;9(34):23482-23493. doi: 10.18632/oncotarget.25235. eCollection 2018 May 4.
84 Exosome-derived miR-339-5p mediates radiosensitivity by targeting Cdc25A in locally advanced esophageal squamous cell carcinoma.Oncogene. 2019 Jun;38(25):4990-5006. doi: 10.1038/s41388-019-0771-0. Epub 2019 Mar 11.
85 Targeting CDC7 improves sensitivity to chemotherapy of esophageal squamous cell carcinoma.Onco Targets Ther. 2018 Dec 20;12:63-74. doi: 10.2147/OTT.S183629. eCollection 2019.
86 miR-200b induces cell cycle arrest and represses cell growth in esophageal squamous cell carcinoma.Carcinogenesis. 2016 Sep;37(9):858-869. doi: 10.1093/carcin/bgw079. Epub 2016 Aug 4.
87 Targeting super-enhancer-associated oncogenes in oesophageal squamous cell carcinoma.Gut. 2017 Aug;66(8):1358-1368. doi: 10.1136/gutjnl-2016-311818. Epub 2016 May 10.
88 Polymorphism rs2395655 affects LEDGF/p75 binding activity and p21WAF1/CIP1 gene expression in esophageal squamous cell carcinoma.Cancer Med. 2019 May;8(5):2313-2324. doi: 10.1002/cam4.2067. Epub 2019 Mar 10.
89 Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762.Toxicol Appl Pharmacol. 2019 Feb 15;365:71-83. doi: 10.1016/j.taap.2019.01.005. Epub 2019 Jan 8.
90 Association of genetic variants in CHEK2 with oesophageal squamous cell carcinoma in the South African Black population.Carcinogenesis. 2019 Jun 10;40(4):513-520. doi: 10.1093/carcin/bgz026.
91 Activation of choline kinase drives aberrant choline metabolism in esophageal squamous cell carcinomas.J Pharm Biomed Anal. 2018 Jun 5;155:148-156. doi: 10.1016/j.jpba.2018.03.062. Epub 2018 Mar 31.
92 Nicotinic cholinergic receptors in esophagus: Early alteration during carcinogenesis and prognostic value.World J Gastroenterol. 2016 Aug 21;22(31):7146-56. doi: 10.3748/wjg.v22.i31.7146.
93 CHST15 promotes the proliferation of TE? cells via multiple pathways in esophageal cancer.Oncol Rep. 2020 Jan;43(1):75-86. doi: 10.3892/or.2019.7395. Epub 2019 Oct 30.
94 High-CLDN4 ESCC cells harbor stem-like properties and indicate for poor concurrent chemoradiation therapy response in esophageal squamous cell carcinoma.Ther Adv Med Oncol. 2019 Sep 27;11:1758835919875324. doi: 10.1177/1758835919875324. eCollection 2019.
95 Chloride intracellular channel 1 as a switch among tumor behaviors in human esophageal squamous cell carcinoma.Oncotarget. 2018 May 1;9(33):23237-23252. doi: 10.18632/oncotarget.25296. eCollection 2018 May 1.
96 Genetic variants in DNA repair pathway genes and risk of esophageal squamous cell carcinoma and gastric adenocarcinoma in a Chinese population.Carcinogenesis. 2013 Jul;34(7):1536-42. doi: 10.1093/carcin/bgt094. Epub 2013 Mar 15.
97 Contactin-1 (CNTN-1) overexpression is correlated with advanced clinical stage and lymph node metastasis in oesophageal squamous cell carcinomas.Jpn J Clin Oncol. 2012 Jul;42(7):612-8. doi: 10.1093/jjco/hys066. Epub 2012 May 11.
98 Clinical significance of LAMB3 and COL7A1 mRNA in esophageal squamous cell carcinoma.Eur J Surg Oncol. 2009 Jan;35(1):52-8. doi: 10.1016/j.ejso.2008.01.025. Epub 2008 Mar 10.
99 Significance of Jab1 expression in human esophageal squamous cell carcinoma.J Clin Gastroenterol. 2009 Jul;43(6):520-6. doi: 10.1097/MCG.0b013e3181919245.
100 Cancer-testis antigen BORIS is a novel prognostic marker for patients with esophageal cancer.Cancer Sci. 2012 Sep;103(9):1617-24. doi: 10.1111/j.1349-7006.2012.02355.x. Epub 2012 Jul 16.
101 Hyperactivity of the transcription factor Nrf2 causes metabolic reprogramming in mouse esophagus.J Biol Chem. 2019 Jan 4;294(1):327-340. doi: 10.1074/jbc.RA118.005963. Epub 2018 Nov 8.
102 Genetic variants in sex hormone metabolic pathway genes and risk of esophageal squamous cell carcinoma.Carcinogenesis. 2013 May;34(5):1062-8. doi: 10.1093/carcin/bgt030. Epub 2013 Jan 28.
103 A genetic polymorphism in the CYP1B1 gene in patients with squamous cell carcinoma of the esophagus: an Iranian Mashhad cohort study recruited over 10years.Pharmacogenomics. 2018 Apr;19(6):539-546. doi: 10.2217/pgs-2018-0197. Epub 2018 Apr 9.
104 Vitamin D Signaling Pathways Confer the Susceptibility of Esophageal Squamous Cell Carcinoma in a Northern Chinese Population.Nutr Cancer. 2017 May-Jun;69(4):593-600. doi: 10.1080/01635581.2017.1299873. Epub 2017 Mar 31.
105 DNA polymorphism and risk of esophageal squamous cell carcinoma in a population of North Xinjiang, China.World J Gastroenterol. 2010 Feb 7;16(5):641-7. doi: 10.3748/wjg.v16.i5.641.
106 Association of Genetic Variants of CYP2C19 and CYP2D6 with Esophageal Squamous Cell Carcinoma Risk in Northern India, Kashmir.Nutr Cancer. 2017 May-Jun;69(4):585-592. doi: 10.1080/01635581.2017.1299874. Epub 2017 Apr 3.
107 Esophageal cancer proliferation is mediated by cytochrome P450 2C9 (CYP2C9).Prostaglandins Other Lipid Mediat. 2011 Feb;94(1-2):25-33. doi: 10.1016/j.prostaglandins.2010.12.001. Epub 2010 Dec 15.
108 Leukotriene receptor expression in esophageal squamous cell cancer and non-transformed esophageal epithelium: a matched case control study.BMC Gastroenterol. 2016 Jul 30;16(1):85. doi: 10.1186/s12876-016-0499-z.
109 Metformin-induced alterations in nucleotide metabolism cause 5-fluorouracil resistance but gemcitabine susceptibility in oesophageal squamous cell carcinoma.J Cell Biochem. 2018 Jan;119(1):1193-1203. doi: 10.1002/jcb.26291. Epub 2017 Aug 23.
110 Overexpression of human -defensin 2 promotes growth and invasion during esophageal carcinogenesis.Oncotarget. 2014 Nov 30;5(22):11333-44. doi: 10.18632/oncotarget.2416.
111 Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence.PLoS Genet. 2018 Mar 14;14(3):e1007227. doi: 10.1371/journal.pgen.1007227. eCollection 2018 Mar.
112 Different functions of DEPTOR in modulating sensitivity to chemotherapy for esophageal squamous cell carcinoma.Exp Cell Res. 2017 Apr 1;353(1):35-45. doi: 10.1016/j.yexcr.2017.03.003. Epub 2017 Mar 4.
113 Decreased expression of DFF45/ICAD is correlated with a poor prognosis in patients with esophageal carcinoma.Cancer. 2002 Dec 15;95(12):2473-8. doi: 10.1002/cncr.10987.
114 The diacylglycerol kinase (DGK)/Akt/NF-B feedforward loop promotes esophageal squamous cell carcinoma (ESCC) progression via FAK-dependent and FAK-independent manner.Oncogene. 2019 Apr;38(14):2533-2550. doi: 10.1038/s41388-018-0604-6. Epub 2018 Dec 7.
115 The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma.Oncogene. 2016 Oct 6;35(40):5304-5316. doi: 10.1038/onc.2016.71. Epub 2016 Apr 4.
116 p63-Dependent Dickkopf3 Expression Promotes Esophageal Cancer Cell Proliferation via CKAP4.Cancer Res. 2018 Nov 1;78(21):6107-6120. doi: 10.1158/0008-5472.CAN-18-1749. Epub 2018 Sep 4.
117 Characterization of gene rearrangements resulted from genomic structural aberrations in human esophageal squamous cell carcinoma KYSE150 cells.Gene. 2013 Jan 15;513(1):196-201. doi: 10.1016/j.gene.2012.09.091. Epub 2012 Sep 28.
118 miR-424 coordinates multilayered regulation of cell cycle progression to promote esophageal squamous cell carcinoma cell proliferation.EBioMedicine. 2018 Nov;37:110-124. doi: 10.1016/j.ebiom.2018.10.043. Epub 2018 Oct 23.
119 High endothelin-converting enzyme-1 expression independently predicts poor survival of patients with esophageal squamous cell carcinoma.Tumour Biol. 2017 Sep;39(9):1010428317725922. doi: 10.1177/1010428317725922.
120 eEF2K promotes progression and radioresistance of esophageal squamous cell carcinoma.Radiother Oncol. 2017 Sep;124(3):439-447. doi: 10.1016/j.radonc.2017.04.001. Epub 2017 Apr 19.
121 A novel long noncoding RNA linc00460 up-regulated by CBP/P300 promotes carcinogenesis in esophageal squamous cell carcinoma.Biosci Rep. 2017 Oct 17;37(5):BSR20171019. doi: 10.1042/BSR20171019. Print 2017 Oct 31.
122 Intratumoral heterogeneity of esophageal squamous cell carcinoma and its clinical significance.Pathol Res Pract. 2019 Feb;215(2):308-314. doi: 10.1016/j.prp.2018.11.019. Epub 2018 Nov 24.
123 High expression of EphA1 in esophageal squamous cell carcinoma is associated with lymph node metastasis and advanced disease.APMIS. 2013 Jan;121(1):30-7. doi: 10.1111/j.1600-0463.2012.02941.x. Epub 2012 Jul 12.
124 EphA2 chimeric antigen receptor-modified T cells for the immunotherapy of esophageal squamous cell carcinoma.J Thorac Dis. 2018 May;10(5):2779-2788. doi: 10.21037/jtd.2018.04.91.
125 Cryptotanshinone inhibits esophageal squamous-cell carcinoma in vitro and in vivo through the suppression of STAT3 activation.Onco Targets Ther. 2019 Jan 29;12:883-896. doi: 10.2147/OTT.S187777. eCollection 2019.
126 Gene Expression Profiling Reveals Distinct Molecular Subtypes of Esophageal Squamous Cell Carcinoma in Asian Populations.Neoplasia. 2019 Jun;21(6):571-581. doi: 10.1016/j.neo.2019.03.013. Epub 2019 Apr 29.
127 Quantitative Proteomics Identify the Possible Tumor Suppressive Role of Protease-Activated Receptor-4 in Esophageal Squamous Cell Carcinoma Cells.Pathol Oncol Res. 2019 Jul;25(3):937-943. doi: 10.1007/s12253-018-0395-7. Epub 2018 Mar 4.
128 Exome-wide analyses identify low-frequency variant in CYP26B1 and additional coding variants associated with esophageal squamous cell carcinoma. Nat Genet. 2018 Mar;50(3):338-343. doi: 10.1038/s41588-018-0045-8. Epub 2018 Jan 29.
129 YAP1 amplification as a prognostic factor of definitive chemoradiotherapy in nonsurgical esophageal squamous cell carcinoma.Cancer Med. 2020 Mar;9(5):1628-1637. doi: 10.1002/cam4.2761. Epub 2019 Dec 18.
130 Genome-wide screening for genetic alterations in esophageal cancer by aCGH identifies 11q13 amplification oncogenes associated with nodal metastasis.PLoS One. 2012;7(6):e39797. doi: 10.1371/journal.pone.0039797. Epub 2012 Jun 25.
131 Blocking FGFR4 exerts distinct anti-tumorigenic effects in esophageal squamous cell carcinoma.Thorac Cancer. 2018 Dec;9(12):1687-1698. doi: 10.1111/1759-7714.12883. Epub 2018 Sep 28.
132 Genomic copy-number alterations of MYC and FHIT genes are associated with survival in esophageal squamous-cell carcinoma.Cancer Sci. 2012 Aug;103(8):1558-66. doi: 10.1111/j.1349-7006.2012.02329.x. Epub 2012 Jun 21.
133 Evaluation of protein expression pattern of stanniocalcin 2, insulin-like growth factor-binding protein 7, inhibin beta A and four and a half LIM domains 1 in esophageal squamous cell carcinoma.Cancer Biomark. 2012-2013;12(1):1-9. doi: 10.3233/CBM-120289.
134 FOXC2 is a novel prognostic factor in human esophageal squamous cell carcinoma.Ann Surg Oncol. 2011 Feb;18(2):535-42. doi: 10.1245/s10434-010-1274-y. Epub 2010 Aug 28.
135 FOXM1c promotes oesophageal cancer metastasis by transcriptionally regulating IRF1 expression.Cell Prolif. 2019 Mar;52(2):e12553. doi: 10.1111/cpr.12553. Epub 2018 Nov 28.
136 FOXO1 overexpression and loss of pSerine256-FOXO1 expression predicts clinical outcome in esophageal adenocarcinomas.Sci Rep. 2018 Nov 26;8(1):17370. doi: 10.1038/s41598-018-35459-4.
137 FOXQ1 promotes esophageal cancer proliferation and metastasis by negatively modulating CDH1.Biomed Pharmacother. 2015 Aug;74:89-94. doi: 10.1016/j.biopha.2015.07.010. Epub 2015 Aug 6.
138 Evaluating stem and cancerous biomarkers in CD15+CD44+ KYSE30 cells.Tumour Biol. 2013 Oct;34(5):2909-20. doi: 10.1007/s13277-013-0853-5.
139 LINC00152 facilitates tumorigenesis in esophageal squamous cell carcinoma via miR-153-3p/FYN axis.Biomed Pharmacother. 2019 Apr;112:108654. doi: 10.1016/j.biopha.2019.108654. Epub 2019 Feb 20.
140 FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma.Oncotarget. 2017 Jul 26;8(39):65957-65968. doi: 10.18632/oncotarget.19586. eCollection 2017 Sep 12.
141 Identification of reference genes and miRNAs for qRT-PCR in human esophageal squamous cell carcinoma.Med Oncol. 2017 Jan;34(1):2. doi: 10.1007/s12032-016-0860-7. Epub 2016 Nov 26.
142 Upregulation of AUF1 is involved in the proliferation of esophageal squamous cell carcinoma through GCH1.Int J Oncol. 2016 Nov;49(5):2001-2010. doi: 10.3892/ijo.2016.3713. Epub 2016 Sep 28.
143 A Novel Clinical Six-Flavoprotein-Gene Signature Predicts Prognosis in Esophageal Squamous Cell Carcinoma.Biomed Res Int. 2019 Oct 30;2019:3869825. doi: 10.1155/2019/3869825. eCollection 2019.
144 Prognostic role of HPV infection in esophageal squamous cell carcinoma.Infect Agent Cancer. 2018 Nov 29;13:38. doi: 10.1186/s13027-018-0210-9. eCollection 2018.
145 Gli1, a potential regulator of esophageal cancer stem cell, is identified as an independent adverse prognostic factor in esophageal squamous cell carcinoma.J Cancer Res Clin Oncol. 2017 Feb;143(2):243-254. doi: 10.1007/s00432-016-2273-6. Epub 2016 Sep 28.
146 Serum pepsinogen assay is not recommended for the diagnosis of esophageal squamous cell carcinoma: a systematic review and meta-analysis.Cancer Manag Res. 2019 Jun 27;11:5643-5654. doi: 10.2147/CMAR.S196760. eCollection 2019.
147 Overexpression of GPR39 contributes to malignant development of human esophageal squamous cell carcinoma.BMC Cancer. 2011 Feb 25;11:86. doi: 10.1186/1471-2407-11-86.
148 Differential expression of G-protein coupled receptor 56 in human esophageal squamous cell carcinoma.Cancer Lett. 2006 Feb 28;233(2):265-70. doi: 10.1016/j.canlet.2005.03.018.
149 A promoter methylation pattern in the N-methyl-D-aspartate receptor 2B gene predicts poor prognosis in esophageal squamous cell carcinoma.Clin Cancer Res. 2007 Nov 15;13(22 Pt 1):6658-65. doi: 10.1158/1078-0432.CCR-07-1178.
150 Histone deacetylases inhibitor MS-275 suppresses human esophageal squamous cell carcinoma cell growth and progression via the PI3K/Akt/mTOR pathway.J Cell Physiol. 2019 Dec;234(12):22400-22410. doi: 10.1002/jcp.28805. Epub 2019 May 23.
151 MiR-601 inhibits the proliferation and metastasis of esophageal squamous cell carcinoma (ESCC) by targeting HDAC6.Eur Rev Med Pharmacol Sci. 2019 Feb;23(3):1069-1076. doi: 10.26355/eurrev_201902_16995.
152 Tenascin-C is involved in promotion of cancer stemness via the Akt/HIF1 axis in esophageal squamous cell carcinoma.Exp Mol Pathol. 2019 Aug;109:104239. doi: 10.1016/j.yexmp.2019.03.007. Epub 2019 Mar 20.
153 HIPK2 inhibits cell metastasis and improves chemosensitivity in esophageal squamous cell carcinoma.Exp Ther Med. 2018 Jan;15(1):1113-1118. doi: 10.3892/etm.2017.5468. Epub 2017 Nov 8.
154 TWIST1, MMP-21, and HLAG-1 co-overexpression is associated with ESCC aggressiveness.J Cell Biochem. 2019 Sep;120(9):14838-14846. doi: 10.1002/jcb.28745. Epub 2019 Apr 23.
155 MiR-490-3p inhibited the proliferation and metastasis of esophageal squamous cell carcinoma by targeting HMGA2.Eur Rev Med Pharmacol Sci. 2018 Dec;22(23):8298-8305. doi: 10.26355/eurrev_201812_16527.
156 Tumor-derived exosomal HMGB1 promotes esophageal squamous cell carcinoma progression through inducing PD1(+) TAM expansion.Oncogenesis. 2019 Feb 22;8(3):17. doi: 10.1038/s41389-019-0126-2.
157 Predictive significance of HMGCS2 for prognosis in resected Chinese esophageal squamous cell carcinoma patients.Onco Targets Ther. 2017 May 15;10:2553-2560. doi: 10.2147/OTT.S132543. eCollection 2017.
158 beta-Catenin/TCF pathway plays a vital role in selenium induced-growth inhibition and apoptosis in esophageal squamous cell carcinoma (ESCC) cells.Cancer Lett. 2010 Oct 1;296(1):113-22. doi: 10.1016/j.canlet.2010.04.001. Epub 2010 May 10.
159 Downregulation of HOXA13 sensitizes human esophageal squamous cell carcinoma to chemotherapy.Thorac Cancer. 2018 Jul;9(7):836-846. doi: 10.1111/1759-7714.12758. Epub 2018 May 14.
160 H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal squamous cell carcinoma.Nucleic Acids Res. 2017 Apr 7;45(6):3086-3101. doi: 10.1093/nar/gkw1247.
161 Prognostic role of HSF1 overexpression in solid tumors: a pooled analysis of 3,159 patients.Onco Targets Ther. 2018 Jan 17;11:383-393. doi: 10.2147/OTT.S153682. eCollection 2018.
162 High expression of glucose-regulated protein 78 (GRP78) is associated with metastasis and poor prognosis in patients with esophageal squamous cell carcinoma.Onco Targets Ther. 2017 Feb 9;10:617-625. doi: 10.2147/OTT.S123494. eCollection 2017.
163 Elevated serine protease HtrA1 inhibits cell proliferation, reduces invasion, and induces apoptosis in esophageal squamous cell carcinoma by blocking the nuclear factor-B signaling pathway.Tumour Biol. 2013 Feb;34(1):317-28. doi: 10.1007/s13277-012-0553-6. Epub 2012 Oct 19.
164 Indoleamine 2,3-dioxygenase 1 and Programmed Cell Death-ligand 1 Co-expression Predicts Poor Pathologic Response and Recurrence in Esophageal Squamous Cell Carcinoma after Neoadjuvant Chemoradiotherapy.Cancers (Basel). 2019 Feb 1;11(2):169. doi: 10.3390/cancers11020169.
165 Polymorphisms of insulin-like growth factor binding protein-3 as a predictor for risk and patient survival in esophageal squamous cell carcinoma.Biomed Pharmacother. 2015 Aug;74:148-52. doi: 10.1016/j.biopha.2015.08.021. Epub 2015 Aug 15.
166 The Diagnostic Value of Serum IGFBP7 in Patients with Esophageal Squamous Cell Carcinoma.J Cancer. 2019 Jun 2;10(12):2687-2693. doi: 10.7150/jca.32393. eCollection 2019.
167 miR-204-5p regulates cell proliferation, invasion, and apoptosis by targeting IL-11 in esophageal squamous cell carcinoma.J Cell Physiol. 2020 Mar;235(3):3043-3055. doi: 10.1002/jcp.29209. Epub 2019 Sep 23.
168 IL-15 receptor alpha rs2228059 A>C polymorphism was associated with a decreased risk of esophageal cancer in a Chinese population.Mol Biol Rep. 2014;41(4):1951-7. doi: 10.1007/s11033-014-3042-8. Epub 2014 Jan 28.
169 Interleukin-23 receptor signaling mediates cancer dormancy and radioresistance in human esophageal squamous carcinoma cells via the Wnt/Notch pathway.J Mol Med (Berl). 2019 Feb;97(2):177-188. doi: 10.1007/s00109-018-1724-8. Epub 2018 Nov 27.
170 Oncogenic IL7R is downregulated by histone deacetylase inhibitor in esophageal squamous cell carcinoma via modulation of acetylated FOXO1.Int J Oncol. 2018 Jul;53(1):395-403. doi: 10.3892/ijo.2018.4392. Epub 2018 May 2.
171 Prognostic significance of IMP-3 expression pattern in esophageal squamous cell carcinoma.J Thorac Dis. 2019 Sep;11(9):3776-3784. doi: 10.21037/jtd.2019.09.25.
172 INHBA upregulation correlates with poorer prognosis in patients with esophageal squamous cell carcinoma.Cancer Manag Res. 2018 Jun 18;10:1585-1596. doi: 10.2147/CMAR.S160186. eCollection 2018.
173 ISG15 promotes esophageal squamous cell carcinoma tumorigenesis via c-MET/Fyn/-catenin signaling pathway.Exp Cell Res. 2018 Jun 1;367(1):47-55. doi: 10.1016/j.yexcr.2018.03.017. Epub 2018 Mar 17.
174 Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/-catenin pathway.Oncotarget. 2015 Mar 20;6(8):6001-13. doi: 10.18632/oncotarget.3469.
175 Integrin 6 promotes esophageal cancer metastasis and is targeted by miR-92b.Oncotarget. 2017 Jan 24;8(4):6681-6690. doi: 10.18632/oncotarget.14259.
176 Identification of prothymosin alpha (PTMA) as a biomarker for esophageal squamous cell carcinoma (ESCC) by label-free quantitative proteomics and Quantitative Dot Blot (QDB).Clin Proteomics. 2019 Apr 5;16:12. doi: 10.1186/s12014-019-9232-6. eCollection 2019.
177 Cancer-associated Fibroblast-promoted LncRNA DNM3OS Confers Radioresistance by Regulating DNA Damage Response in Esophageal Squamous Cell Carcinoma.Clin Cancer Res. 2019 Mar 15;25(6):1989-2000. doi: 10.1158/1078-0432.CCR-18-0773. Epub 2018 Nov 21.
178 The increase of voltage-gated potassium channel Kv3.4 mRNA expression in oral squamous cell carcinoma.J Oral Pathol Med. 2003 Nov;32(10):606-11. doi: 10.1034/j.1600-0714.2003.00197.x.
179 TCF7L2 and EGR1 synergistic activation of transcription of LCN2 via an ERK1/2-dependent pathway in esophageal squamous cell carcinoma cells.Cell Signal. 2019 Mar;55:8-16. doi: 10.1016/j.cellsig.2018.12.007. Epub 2018 Dec 14.
180 Identification and characterization of JMJD2 family genes in silico.Int J Oncol. 2004 Jun;24(6):1623-8.
181 Blockade of Immune-Checkpoint B7-H4 and Lysine Demethylase 5B in Esophageal Squamous Cell Carcinoma Confers Protective Immunity against P. gingivalis Infection.Cancer Immunol Res. 2019 Sep;7(9):1440-1456. doi: 10.1158/2326-6066.CIR-18-0709. Epub 2019 Jul 26.
182 KIF11 Is Required for Spheroid Formation by Oesophageal and Colorectal Cancer Cells.Anticancer Res. 2017 Jan;37(1):47-55. doi: 10.21873/anticanres.11287.
183 miR-92b-3p Functions As A Key Gene In Esophageal Squamous Cell Cancer As Determined By Co-Expression Analysis.Onco Targets Ther. 2019 Oct 14;12:8339-8353. doi: 10.2147/OTT.S220823. eCollection 2019.
184 miR-502 medaited histone methyltransferase SET8 expression is associated with outcome of esophageal squamous cell carcinoma.Sci Rep. 2016 Sep 8;6:32921. doi: 10.1038/srep32921.
185 Keratin 17 activates AKT signalling and induces epithelial-mesenchymal transition in oesophageal squamous cell carcinoma.J Proteomics. 2020 Jan 16;211:103557. doi: 10.1016/j.jprot.2019.103557. Epub 2019 Oct 24.
186 Altered expression of lysosomal associated membrane protein 1 in esophageal squamous cell carcinoma.Pathol Res Pract. 2017 Aug;213(8):938-942. doi: 10.1016/j.prp.2017.05.008. Epub 2017 May 31.
187 High expression of LAMP2 predicts poor prognosis in patients with esophageal squamous cell carcinoma.Cancer Biomark. 2017 Jul 4;19(3):305-311. doi: 10.3233/CBM-160469.
188 Relationship between LAPTM4B gene polymorphism and susceptibility of gastric cancer.Ann Oncol. 2007 Feb;18(2):311-6. doi: 10.1093/annonc/mdl394. Epub 2006 Oct 30.
189 Upregulation of the long non-coding RNA PVT1 promotes esophageal squamous cell carcinoma progression by acting as a molecular sponge of miR-203 and LASP1.Oncotarget. 2017 May 23;8(21):34164-34176. doi: 10.18632/oncotarget.15878.
190 Downregulation of MiR-31 stimulates expression of LATS2 via the hippo pathway and promotes epithelial-mesenchymal transition in esophageal squamous cell carcinoma.J Exp Clin Cancer Res. 2017 Nov 16;36(1):161. doi: 10.1186/s13046-017-0622-1.
191 Glucose transporter 1 regulates the proliferation and cisplatin sensitivity of esophageal cancer.Cancer Sci. 2019 May;110(5):1705-1714. doi: 10.1111/cas.13995. Epub 2019 Apr 5.
192 B7H4 is associated with stemness and cancer progression in esophageal squamous cell carcinoma.Hum Pathol. 2018 Oct;80:152-162. doi: 10.1016/j.humpath.2018.05.021. Epub 2018 Jun 6.
193 Overexpression of a splice variant of oncostatin M receptor beta in human esophageal squamous carcinoma.Cell Oncol (Dordr). 2011 Jun;34(3):177-87. doi: 10.1007/s13402-011-0011-2. Epub 2011 Mar 11.
194 MicroRNA-384 inhibits the progression of esophageal squamous cell carcinoma through blockade of the LIMK1/cofilin signaling pathway by binding to LIMK1.Biomed Pharmacother. 2019 Jan;109:751-761. doi: 10.1016/j.biopha.2018.09.110. Epub 2018 Nov 5.
195 Lin28/microRNA-let-7a promotes metastasis under circumstances of hyperactive Wnt signaling in esophageal squamous cell carcinoma.Mol Med Rep. 2018 Apr;17(4):5265-5271. doi: 10.3892/mmr.2018.8548. Epub 2018 Feb 2.
196 Overexpression of Pim-1 is associated with poor prognosis in patients with esophageal squamous cell carcinoma.J Surg Oncol. 2010 Nov 1;102(6):683-8. doi: 10.1002/jso.21627.
197 LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.Cancer Res. 2019 Oct 1;79(19):4951-4964. doi: 10.1158/0008-5472.CAN-19-0860. Epub 2019 Aug 13.
198 Cigarette smoke induces promoter methylation of single-stranded DNA-binding protein 2 in human esophageal squamous cell carcinoma.Int J Cancer. 2011 May 15;128(10):2261-73. doi: 10.1002/ijc.25569.
199 Serological antibodies against LY6K as a diagnostic biomarker in esophageal squamous cell carcinoma.Biomarkers. 2012 Jun;17(4):372-8. doi: 10.3109/1354750X.2012.680609. Epub 2012 Apr 19.
200 The expression of high mobility group box 1 is associated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma.Pathol Oncol Res. 2012 Oct;18(4):1021-7. doi: 10.1007/s12253-012-9539-3. Epub 2012 Apr 29.
201 Expressions of melanoma-associated antigen A1 as a prognostic factor in Chinese patients with resectable oesophageal squamous cell carcinoma.Interact Cardiovasc Thorac Surg. 2019 Oct 1;29(4):510-516. doi: 10.1093/icvts/ivz141.
202 Efficient induction of anti-tumor immune response in esophageal squamous cell carcinoma via dendritic cells expressing MAGE-A3 and CALR antigens.Cell Immunol. 2015 Jun;295(2):77-82. doi: 10.1016/j.cellimm.2015.03.011. Epub 2015 Apr 4.
203 [ARTICLE WITHDRAWN] MicroRNA-539 Inhibits the Epithelial-Mesenchymal Transition of Esophageal Cancer Cells by Twist-Related Protein 1-Mediated Modulation of Melanoma-Associated Antigen A4.Oncol Res. 2018 May 7;26(4):529-536. doi: 10.3727/096504017X14972679378357. Epub 2017 Jun 12.
204 Investigation into the expression levels of MAGEA6 in esophageal squamous cell carcinoma and esophageal adenocarcinoma tissues.Exp Ther Med. 2019 Sep;18(3):1816-1822. doi: 10.3892/etm.2019.7735. Epub 2019 Jul 5.
205 Polymorphic variation of the ARP gene on 3p21 in Japanese esophageal cancer patients.Oncol Rep. 2000 May-Jun;7(3):591-3. doi: 10.3892/or.7.3.591.
206 MTA1 promotes tumorigenesis and development of esophageal squamous cell carcinoma via activating the MEK/ERK/p90RSK signaling pathway.Carcinogenesis. 2020 Sep 24;41(9):1263-1272. doi: 10.1093/carcin/bgz200.
207 MicroRNA-148a regulates the MAPK/ERK signaling pathway and suppresses the development of esophagus squamous cell carcinoma via targeting MAP3K9.Eur Rev Med Pharmacol Sci. 2019 Aug;23(15):6497-6504. doi: 10.26355/eurrev_201908_18533.
208 Microtubule-associated protein 4 is an important regulator of cell invasion/migration and a potential therapeutic target in esophageal squamous cell carcinoma.Oncogene. 2016 Sep 15;35(37):4846-56. doi: 10.1038/onc.2016.17. Epub 2016 Feb 15.
209 Licochalcone H Synthesized by Modifying Structure of Licochalcone C Extracted from Glycyrrhiza inflata Induces Apoptosis of Esophageal Squamous Cell Carcinoma Cells.Cell Biochem Biophys. 2020 Mar;78(1):65-76. doi: 10.1007/s12013-019-00892-3. Epub 2019 Nov 9.
210 Clinical significance of mannose-binding lectin-associated serine protease-2 expression in esophageal squamous cell carcinoma.Int J Cancer. 2006 Jun 15;118(12):2930-5. doi: 10.1002/ijc.21721.
211 Pemetrexed exerts anticancer effects by inducing G(0)/G(1)-phase cell cycle arrest and activating the NOXA/Mcl-1 axis in human esophageal squamous cell carcinoma cells.Oncol Lett. 2019 Feb;17(2):1851-1858. doi: 10.3892/ol.2018.9753. Epub 2018 Nov 23.
212 MCM7 amplification and overexpression promote cell proliferation, colony formation and migration in esophageal squamous cell carcinoma by activating the AKT1/mTOR signaling pathway.Oncol Rep. 2017 Jun;37(6):3590-3596. doi: 10.3892/or.2017.5614. Epub 2017 May 2.
213 miR-145 sensitizes esophageal squamous cell carcinoma to cisplatin through directly inhibiting PI3K/AKT signaling pathway.Cancer Cell Int. 2019 Sep 30;19:250. doi: 10.1186/s12935-019-0943-6. eCollection 2019.
214 Immunoregulatory influence of abundant MFG-E8 expression by esophageal cancer treated with chemotherapy.Cancer Sci. 2018 Nov;109(11):3393-3402. doi: 10.1111/cas.13785. Epub 2018 Sep 22.
215 Promoter methylation of MGMT gene in serum of patients with esophageal squamous cell carcinoma in North East India.Asian Pac J Cancer Prev. 2014;15(22):9955-60. doi: 10.7314/apjcp.2014.15.22.9955.
216 Overexpression of matrix metalloproteinase 10 is associated with poor survival in patients with early stage of esophageal squamous cell carcinoma.Dis Esophagus. 2012 Sep-Oct;25(7):656-63. doi: 10.1111/j.1442-2050.2011.01284.x. Epub 2011 Nov 28.
217 SDR9C7 promotes lymph node metastases in patients with esophageal squamous cell carcinoma.PLoS One. 2013;8(1):e52184. doi: 10.1371/journal.pone.0052184. Epub 2013 Jan 14.
218 Regulation of MMP13 by antitumor microRNA-375 markedly inhibits cancer cell migration and invasion in esophageal squamous cell carcinoma.Int J Oncol. 2016 Dec;49(6):2255-2264. doi: 10.3892/ijo.2016.3745. Epub 2016 Oct 21.
219 High expression of Collagen Triple Helix Repeat Containing 1 (CTHRC1) facilitates progression of oesophageal squamous cell carcinoma through MAPK/MEK/ERK/FRA-1 activation.J Exp Clin Cancer Res. 2017 Jun 23;36(1):84. doi: 10.1186/s13046-017-0555-8.
220 MT3-MMP down-regulation promotes tumorigenesis and correlates to poor prognosis in esophageal squamous cell carcinoma.Cancer Med. 2016 Sep;5(9):2459-68. doi: 10.1002/cam4.790. Epub 2016 Jun 12.
221 BRCA2 loss-of-function germline mutations are associated with esophageal squamous cell carcinoma risk in Chinese.Int J Cancer. 2020 Feb 15;146(4):1042-1051. doi: 10.1002/ijc.32619. Epub 2019 Aug 26.
222 WNT and NOTCH signaling pathways as activators for epidermal growth factor receptor in esophageal squamous cell carcinoma.Cell Mol Biol Lett. 2018 Sep 3;23:42. doi: 10.1186/s11658-018-0109-x. eCollection 2018.
223 Msi2 plays a carcinogenic role in esophageal squamous cell carcinoma via regulation of the Wnt/-catenin and Hedgehog signaling pathways.Exp Cell Res. 2017 Dec 1;361(1):170-177. doi: 10.1016/j.yexcr.2017.10.016. Epub 2017 Oct 18.
224 Genetic variants at 9p21.3 are associated with risk of esophageal squamous cell carcinoma in a Chinese population.Cancer Sci. 2017 Feb;108(2):250-255. doi: 10.1111/cas.13130.
225 Polymorphisms in methionine synthase (A2756G) and cystathionine beta-synthase (844ins68) and susceptibility to carcinomas of the upper gastrointestinal tract.J Cancer Res Clin Oncol. 2008 Mar;134(3):405-10. doi: 10.1007/s00432-007-0301-2. Epub 2007 Aug 29.
226 Downregulation of MUTYH contributes to cisplatinresistance of esophageal squamous cell carcinoma cells by promoting Twistmediated EMT.Oncol Rep. 2019 Dec;42(6):2716-2727. doi: 10.3892/or.2019.7347. Epub 2019 Oct 1.
227 The implications and mechanisms of the extra-nuclear nucleolin in the esophageal squamous cell carcinomas.Med Oncol. 2015 Mar;32(3):45. doi: 10.1007/s12032-015-0484-3. Epub 2015 Jan 29.
228 A novel Myc-target gene, mimitin, that is involved in cell proliferation of esophageal squamous cell carcinoma.J Biol Chem. 2005 May 20;280(20):19977-85. doi: 10.1074/jbc.M501231200. Epub 2005 Mar 17.
229 Neddylation inhibitor MLN4924 induces G(2) cell cycle arrest, DNA damage and sensitizes esophageal squamous cell carcinoma cells to cisplatin.Oncol Lett. 2018 Feb;15(2):2583-2589. doi: 10.3892/ol.2017.7616. Epub 2017 Dec 14.
230 Hypermethylation of the nel-like 1 gene is a common and early event and is associated with poor prognosis in early-stage esophageal adenocarcinoma. Oncogene. 2007 Sep 20;26(43):6332-40. doi: 10.1038/sj.onc.1210461. Epub 2007 Apr 23.
231 Expression and clinical significance of p75NTR in esophageal squamous cell carcinoma.Math Biosci Eng. 2019 Sep 5;16(6):8060-8068. doi: 10.3934/mbe.2019405.
232 miR-4319 Suppresses the Growth of Esophageal Squamous Cell Carcinoma Via Targeting NLRC5.Curr Mol Pharmacol. 2020;13(2):144-149. doi: 10.2174/1874467212666191119094636.
233 Comparison between neoadjuvant chemotherapy followed by surgery and definitive chemoradiotherapy for overall survival in patients with clinical Stage II/III esophageal squamous cell carcinoma (JCOG1406-A).Jpn J Clin Oncol. 2017 Jun 1;47(6):480-486. doi: 10.1093/jjco/hyx040.
234 Comparative proteomic analysis of beta-catenin-mediated malignant progression of esophageal squamous cell carcinoma.Dis Esophagus. 2010 Feb;23(2):175-84. doi: 10.1111/j.1442-2050.2009.01001.x. Epub 2009 Jul 31.
235 MicroRNA-1 suppresses proliferation, migration and invasion by targeting Notch2 in esophageal squamous cell carcinoma.Sci Rep. 2018 Mar 26;8(1):5183. doi: 10.1038/s41598-018-23421-3.
236 Expression of natriuretic peptide receptor-A in esophageal squamous cell carcinomas and the relationship with tumor invasion and migration.World J Surg Oncol. 2014 May 21;12:154. doi: 10.1186/1477-7819-12-154.
237 Combination treatment with highly bioavailable curcumin and NQO1 inhibitor exhibits potent antitumor effects on esophageal squamous cell carcinoma.J Gastroenterol. 2019 Aug;54(8):687-698. doi: 10.1007/s00535-019-01549-x. Epub 2019 Feb 8.
238 NQO1 rs1800566 C>T polymorphism was associated with a decreased risk of esophageal cancer in a Chinese population.Scand J Gastroenterol. 2014 Mar;49(3):317-22. doi: 10.3109/00365521.2013.873819. Epub 2013 Dec 19.
239 Genetic variants in nucleotide excision repair pathway predict survival of esophageal squamous cell cancer patients receiving platinum-based chemotherapy.Mol Carcinog. 2018 Nov;57(11):1553-1565. doi: 10.1002/mc.22877. Epub 2018 Aug 12.
240 Neuropilin-2 promotes tumourigenicity and metastasis in oesophageal squamous cell carcinoma through ERK-MAPK-ETV4-MMP-E-cadherin deregulation.J Pathol. 2016 Jul;239(3):309-19. doi: 10.1002/path.4728. Epub 2016 May 5.
241 Ornithine decarboxylase inhibition downregulates multiple pathways involved in the formation of precancerous lesions of esophageal squamous cell cancer.Mol Carcinog. 2020 Feb;59(2):215-226. doi: 10.1002/mc.23144. Epub 2019 Dec 3.
242 Effect of hOGG1 over-expression on cisplatin resistance in esophageal squamous carcinoma cells.Cancer Biother Radiopharm. 2013 Jul-Aug;28(6):433-40. doi: 10.1089/cbr.2012.1287. Epub 2013 Jun 27.
243 Selective inhibitory effects of zinc on cell proliferation in esophageal squamous cell carcinoma through Orai1.FASEB J. 2018 Jan;32(1):404-416. doi: 10.1096/fj.201700227RRR. Epub 2017 Sep 19.
244 Expression and prognostic roles of PABPC1 in esophageal cancer: correlation with tumor progression and postoperative survival.Oncol Rep. 2006 Mar;15(3):667-71.
245 PADI4 stimulates esophageal squamous cell carcinoma tumor growth and up-regulates CA9 expression.Mol Carcinog. 2019 Jan;58(1):66-75. doi: 10.1002/mc.22907. Epub 2018 Oct 21.
246 Investigation of NQO1 genetic polymorphism, NQO1 gene expression and PAH-DNA adducts in ESCC. A case-control study from Iran.Genet Mol Res. 2010 Feb 9;9(1):239-49. doi: 10.4238/vol9-1gmr693.
247 Clinical relevance of PD-L1 and PD-L2 overexpression in patients with esophageal squamous cell carcinoma.J Thorac Dis. 2018 Jul;10(7):4433-4444. doi: 10.21037/jtd.2018.06.167.
248 Down-regulation of platelet-derived growth factor-D expression blockades NF-B pathway to inhibit cell proliferation and invasion as well as induce apoptosis in esophageal squamous cell carcinoma.Mol Biol Rep. 2013 Mar;40(3):2473-83. doi: 10.1007/s11033-012-2328-y. Epub 2012 Nov 28.
249 Upregulation of PDK1 associates with poor prognosis in esophageal squamous cell carcinoma with facilitating tumorigenicity in vitro.Med Oncol. 2014 Dec;31(12):337. doi: 10.1007/s12032-014-0337-5. Epub 2014 Nov 22.
250 Dysregulated expression of HOX and ParaHOX genes in human esophageal squamous cell carcinoma.Oncol Rep. 2007 Apr;17(4):753-60.
251 Promoter methylation and expression of Raf kinase inhibitory protein in esophageal squamous cell carcinoma.Oncol Lett. 2017 Mar;13(3):1866-1872. doi: 10.3892/ol.2017.5617. Epub 2017 Jan 18.
252 APC/C-CDH1-Regulated IDH3 Coordinates with the Cell Cycle to Promote Cell Proliferation.Cancer Res. 2019 Jul 1;79(13):3281-3293. doi: 10.1158/0008-5472.CAN-18-2341. Epub 2019 May 3.
253 Expression of PGDH correlates with cell growth in both esophageal squamous cell carcinoma and adenocarcinoma.Asian Pac J Cancer Prev. 2015;16(3):997-1000. doi: 10.7314/apjcp.2015.16.3.997.
254 Pseudogene PHBP1 promotes esophageal squamous cell carcinoma proliferation by increasing its cognate gene PHB expression.Oncotarget. 2017 Apr 25;8(17):29091-29100. doi: 10.18632/oncotarget.16196.
255 Downregulation of microRNA-370 in esophageal squamous-cell carcinoma is associated with cancer progression and promotes cancer cell proliferation via upregulating PIN1.Gene. 2018 Jun 30;661:68-77. doi: 10.1016/j.gene.2018.03.090. Epub 2018 Mar 29.
256 PKM2-regulated STAT3 promotes esophageal squamous cell carcinoma progression via TGF-1-induced EMT.J Cell Biochem. 2019 Jul;120(7):11539-11550. doi: 10.1002/jcb.28434. Epub 2019 Feb 12.
257 Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma.Cancer Manag Res. 2019 Aug 19;11:7813-7824. doi: 10.2147/CMAR.S214243. eCollection 2019.
258 Association of serum annexin A1 with treatment response and prognosis in patients with esophageal squamous cell carcinoma.J Cancer Res Ther. 2018 Sep;14(Supplement):S667-S674. doi: 10.4103/0973-1482.187297.
259 A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma.EBioMedicine. 2019 Mar;41:244-255. doi: 10.1016/j.ebiom.2019.02.012. Epub 2019 Mar 12.
260 Association of ECRG4 with PLK1, CDK4, PLOD1 and PLOD2 in esophageal squamous cell carcinoma.Am J Transl Res. 2017 Aug 15;9(8):3741-3748. eCollection 2017.
261 DNA polymerase mutations and survival of patients with esophageal squamous cell carcinoma in Linzhou City, China.Tumour Biol. 2014 Jan;35(1):553-9. doi: 10.1007/s13277-013-1077-4.
262 PKC iota promotes cellular proliferation by accelerated G1/S transition via interaction with CDK7 in esophageal squamous cell carcinoma.Tumour Biol. 2016 Oct;37(10):13799-13809. doi: 10.1007/s13277-016-5193-9. Epub 2016 Aug 1.
263 Protein kinase D1mRNA level may predict cancer-specific survival in heavy smokers with esophageal squamous cell cancers.Dis Esophagus. 2014 Feb-Mar;27(2):188-95. doi: 10.1111/dote.12077. Epub 2013 Apr 26.
264 MicroRNA-488-3p inhibits proliferation and induces apoptosis by targeting ZBTB2 in esophageal squamous cell carcinoma.J Cell Biochem. 2019 Nov;120(11):18702-18713. doi: 10.1002/jcb.29178. Epub 2019 Jun 26.
265 PRMT1 regulates the tumour-initiating properties of esophageal squamous cell carcinoma through histone H4 arginine methylation coupled with transcriptional activation.Cell Death Dis. 2019 May 1;10(5):359. doi: 10.1038/s41419-019-1595-0.
266 PRSS8 methylation and its significance in esophageal squamous cell carcinoma.Oncotarget. 2016 May 10;7(19):28540-55. doi: 10.18632/oncotarget.8677.
267 Genetic variants at 8q24 are associated with risk of esophageal squamous cell carcinoma in a Chinese population.Cancer Sci. 2014 Jun;105(6):731-5. doi: 10.1111/cas.12399. Epub 2014 Apr 13.
268 Genetic variability in LMP2 and LMP7 is associated with the risk of esophageal squamous cell carcinoma in the Kazakh population but is not associated with HPV infection.PLoS One. 2017 Oct 26;12(10):e0186319. doi: 10.1371/journal.pone.0186319. eCollection 2017.
269 Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis.Carcinogenesis. 2010 Mar;31(3):427-34. doi: 10.1093/carcin/bgp326. Epub 2009 Dec 30.
270 The arachidonic acid metabolism protein-protein interaction network and its expression pattern in esophageal diseases.Am J Transl Res. 2018 Mar 15;10(3):907-924. eCollection 2018.
271 Role of ALDH1 in the prognosis of esophageal cancer and its relationship with tumor microenvironment.Mol Carcinog. 2018 Jan;57(1):78-88. doi: 10.1002/mc.22733. Epub 2017 Oct 9.
272 Catalytically inactive receptor tyrosine kinase PTK7 activates FGFR1 independent of FGF.FASEB J. 2019 Nov;33(11):12960-12971. doi: 10.1096/fj.201900932R. Epub 2019 Sep 18.
273 Expression of phosphatase of regenerating liver 1 and 3 mRNA in esophageal squamous cell carcinoma.Arch Pathol Lab Med. 2008 Aug;132(8):1307-12. doi: 10.5858/2008-132-1307-EOPORL.
274 RACKI induces chemotherapy resistance in esophageal carcinoma by upregulating the PI3K/AKT pathway and Bcl-2 expression.Onco Targets Ther. 2018 Jan 4;11:211-220. doi: 10.2147/OTT.S152818. eCollection 2018.
275 HiFreSP: A novel high-frequency sub-pathway mining approach to identify robust prognostic gene signatures.Brief Bioinform. 2020 Jul 15;21(4):1411-1424. doi: 10.1093/bib/bbz078.
276 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone induces retinoic acid receptor hypermethylation through DNA methyltransferase 1 accumulation in esophageal squamous epithelial cells.Asian Pac J Cancer Prev. 2012;13(5):2207-12. doi: 10.7314/apjcp.2012.13.5.2207.
277 Promoter hypermethylation of the RECK gene is associated with its low expression and poor survival of esophageal squamous cell carcinoma.Oncol Lett. 2017 Mar;13(3):1911-1918. doi: 10.3892/ol.2017.5656. Epub 2017 Jan 27.
278 RHCG Suppresses Tumorigenicity and Metastasis in Esophageal Squamous Cell Carcinoma via Inhibiting NF-B Signaling and MMP1 Expression.Theranostics. 2018 Jan 1;8(1):185-198. doi: 10.7150/thno.21383. eCollection 2018.
279 RICTOR expression in esophageal squamous cell carcinoma and its clinical significance.Med Oncol. 2017 Mar;34(3):32. doi: 10.1007/s12032-017-0894-5. Epub 2017 Jan 28.
280 Identification of somatic mutations of the RNF6 gene in human esophageal squamous cell carcinoma.Cancer Res. 2002 Aug 1;62(15):4191-3.
281 miR-1179 promotes cell invasion through SLIT2/ROBO1 axis in esophageal squamous cell carcinoma.Int J Clin Exp Pathol. 2015 Jan 1;8(1):319-27. eCollection 2015.
282 Lapachol is a novel ribosomal protein S6 kinase 2 inhibitor that suppresses growth and induces intrinsic apoptosis in esophageal squamous cell carcinoma cells.Phytother Res. 2019 Sep;33(9):2337-2346. doi: 10.1002/ptr.6415. Epub 2019 Jun 21.
283 An Association and Meta-Analysis of Esophageal Squamous Cell Carcinoma Risk Associated with PLCE1 rs2274223, C20orf54 rs13042395 and RUNX1 rs2014300 Polymorphisms.Pathol Oncol Res. 2020 Apr;26(2):681-692. doi: 10.1007/s12253-019-00579-3. Epub 2019 Jan 21.
284 Effect and mechanism of RUNX3 gene on biological characteristics of human esophageal squamous cell carcinoma (ESCC).Med Oncol. 2015 Jan;32(1):357. doi: 10.1007/s12032-014-0357-1. Epub 2014 Nov 27.
285 The prognostic significance of cancer-associated fibroblasts in esophageal squamous cell carcinoma.PLoS One. 2014 Jun 19;9(6):e99955. doi: 10.1371/journal.pone.0099955. eCollection 2014.
286 S1PR1 promotes proliferation and inhibits apoptosis of esophageal squamous cell carcinoma through activating STAT3 pathway.J Exp Clin Cancer Res. 2019 Aug 22;38(1):369. doi: 10.1186/s13046-019-1369-7.
287 Special AT-rich sequence binding protein 1 promotes tumor growth and metastasis of esophageal squamous cell carcinoma.Tumour Biol. 2017 Mar;39(3):1010428317694537. doi: 10.1177/1010428317694537.
288 Prognostic significance of altered expression of SDC2 and CYR61 in esophageal squamous cell carcinoma.Oncol Rep. 2009 Apr;21(4):1123-9. doi: 10.3892/or_00000332.
289 SEMA4D under the posttranscriptional regulation of HuR and miR-4319 boosts cancer progression in esophageal squamous cell carcinoma.Cancer Biol Ther. 2020;21(2):122-129. doi: 10.1080/15384047.2019.1669996. Epub 2019 Oct 25.
290 Association between SNPs in Serpin gene family and risk of esophageal squamous cell carcinoma.Tumour Biol. 2015 Aug;36(8):6231-8. doi: 10.1007/s13277-015-3308-3. Epub 2015 Mar 17.
291 Overexpression of HSP47 in esophageal squamous cell carcinoma: clinical implications and functional analysis.Dis Esophagus. 2016 Oct;29(7):848-855. doi: 10.1111/dote.12359. Epub 2015 May 8.
292 Role of the Na ?K ?2Cl?cotransporter NKCC1 in cell cycle progression in human esophageal squamous cell carcinoma.World J Gastroenterol. 2014 Jun 14;20(22):6844-59. doi: 10.3748/wjg.v20.i22.6844.
293 Prognostic value of monocarboxylate transporter 4 in patients with esophageal squamous cell carcinoma.Oncol Rep. 2018 Nov;40(5):2906-2915. doi: 10.3892/or.2018.6706. Epub 2018 Sep 13.
294 Genetic polymorphisms in SLC23A2 as predictive biomarkers of severe acute toxicities after treatment with a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma.Int J Med Sci. 2014 Feb 7;11(4):321-6. doi: 10.7150/ijms.7654. eCollection 2014.
295 Circ-SLC7A5, a potential prognostic circulating biomarker for detection of ESCC.Cancer Genet. 2020 Jan;240:33-39. doi: 10.1016/j.cancergen.2019.11.001. Epub 2019 Nov 5.
296 Na+/H+ exchanger 1 has tumor suppressive activity and prognostic value in esophageal squamous cell carcinoma.Oncotarget. 2017 Jan 10;8(2):2209-2223. doi: 10.18632/oncotarget.13645.
297 SMYD2 overexpression is associated with tumor cell proliferation and a worse outcome in human papillomavirus-unrelated nonmultiple head and neck carcinomas.Hum Pathol. 2016 Mar;49:145-55. doi: 10.1016/j.humpath.2015.08.025. Epub 2015 Nov 4.
298 Long noncoding RNA CASC2 suppresses esophageal squamous cell carcinoma progression by increasing SOCS1 expression.Cell Biosci. 2019 Nov 9;9:90. doi: 10.1186/s13578-019-0353-4. eCollection 2019.
299 Regulation of SPOCK1 by dual strands of pre-miR-150 inhibit cancer cell migration and invasion in esophageal squamous cell carcinoma.J Hum Genet. 2017 Nov;62(11):935-944. doi: 10.1038/jhg.2017.69. Epub 2017 Jun 29.
300 SREBP2 is upregulated in esophageal squamous cell carcinoma and cooperates with cMyc to regulate HMGCR expression.Mol Med Rep. 2019 Oct;20(4):3003-3010. doi: 10.3892/mmr.2019.10577. Epub 2019 Aug 9.
301 Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.Nat Genet. 2012 Oct;44(10):1090-7. doi: 10.1038/ng.2411. Epub 2012 Sep 9.
302 The crucial role of SRPK1 in TGF--induced proliferation and apoptosis in the esophageal squamous cell carcinomas.Med Oncol. 2015 Jul;32(7):209. doi: 10.1007/s12032-015-0654-3. Epub 2015 Jun 23.
303 Expression of EMMPRIN and matriptase in esophageal squamous cell carcinoma: correlation with clinicopathological parameters.Dis Esophagus. 2006;19(6):482-6. doi: 10.1111/j.1442-2050.2006.00613.x.
304 MLL2 promotes cancer cell lymph node metastasis by interacting with RelA and facilitating STC1 transcription.Cell Signal. 2020 Jan;65:109457. doi: 10.1016/j.cellsig.2019.109457. Epub 2019 Oct 30.
305 Stomatin-like protein 2 is overexpressed in cancer and involved in regulating cell growth and cell adhesion in human esophageal squamous cell carcinoma.Clin Cancer Res. 2006 Mar 1;12(5):1639-46. doi: 10.1158/1078-0432.CCR-05-1858.
306 Clinical significance of LOXL4 expression and features of LOXL4-associated protein-protein interaction network in esophageal squamous cell carcinoma.Amino Acids. 2019 May;51(5):813-828. doi: 10.1007/s00726-019-02723-4. Epub 2019 Mar 21.
307 Identification of PA28 as a potential novel biomarker in human esophageal squamous cell carcinoma.Tumour Biol. 2017 Oct;39(10):1010428317719780. doi: 10.1177/1010428317719780.
308 The tumor-suppressive function of miR-1 by targeting LASP1 and TAGLN2 in esophageal squamous cell carcinoma.J Gastroenterol Hepatol. 2016 Feb;31(2):384-93. doi: 10.1111/jgh.13180.
309 Association between the genetic variations within TBX21 gene promoter and the clinicopathological characteristics of esophageal squamous cell carcinoma in a high-risk Chinese population.Tumour Biol. 2015 May;36(5):3985-93. doi: 10.1007/s13277-015-3042-x. Epub 2015 Jan 11.
310 TDO2 Overexpression Is Associated with Cancer Stem Cells and Poor Prognosis in Esophageal Squamous Cell Carcinoma.Oncology. 2018;95(5):297-308. doi: 10.1159/000490725. Epub 2018 Aug 22.
311 Expression and mechanism of PinX1 and telomerase activity in the carcinogenesis of esophageal epithelial cells.Oncol Rep. 2013 Oct;30(4):1823-31. doi: 10.3892/or.2013.2649. Epub 2013 Aug 1.
312 TFF1 hypermethylation and decreased expression in esophageal squamous cell carcinoma and histologically normal tumor surrounding esophageal cells.Clin Epigenetics. 2017 Dec 20;9:130. doi: 10.1186/s13148-017-0429-0. eCollection 2017.
313 Concordant promoter methylation of transforming growth factor-beta receptor types I and II occurs early in esophageal squamous cell carcinoma.Am J Med Sci. 2012 May;343(5):375-81. doi: 10.1097/MAJ.0b013e3182253430.
314 THRB genetic polymorphisms can predict severe myelotoxicity after definitive chemoradiotherapy in patients with esophageal squamous cell carcinoma.Int J Med Sci. 2012;9(9):748-56. doi: 10.7150/ijms.5081. Epub 2012 Oct 23.
315 Tumor-suppressive microRNA-10a inhibits cell proliferation and metastasis by targeting Tiam1 in esophageal squamous cell carcinoma.J Cell Biochem. 2019 May;120(5):7845-7857. doi: 10.1002/jcb.28059. Epub 2018 Nov 13.
316 The analyses of SRCR genes based on protein-protein interaction network in esophageal squamous cell carcinoma.Am J Transl Res. 2019 May 15;11(5):2683-2705. eCollection 2019.
317 Thymosin 4 expression in human tissues and in tumors using tissue microarrays.Appl Immunohistochem Mol Morphol. 2011 Mar;19(2):160-7. doi: 10.1097/PAI.0b013e3181f12237.
318 Neddylation Inhibition Activates the Extrinsic Apoptosis Pathway through ATF4-CHOP-DR5 Axis in Human Esophageal Cancer Cells.Clin Cancer Res. 2016 Aug 15;22(16):4145-57. doi: 10.1158/1078-0432.CCR-15-2254. Epub 2016 Mar 16.
319 Significant involvement of herpesvirus entry mediator in human esophageal squamous cell carcinoma.Cancer. 2014 Mar 15;120(6):808-17. doi: 10.1002/cncr.28491. Epub 2013 Nov 18.
320 Clinical significance of tumor necrosis factor receptor 2 in middle and lower thoracic esophageal squamous cell carcinoma.Oncol Lett. 2018 Sep;16(3):2971-2978. doi: 10.3892/ol.2018.8998. Epub 2018 Jun 20.
321 Clinical significance and prognostic value of TRIM24 expression in esophageal squamous cell carcinoma.Aging (Albany NY). 2016 Sep 28;8(9):2204-2221. doi: 10.18632/aging.101037.
322 TRIM27 promotes the development of esophagus cancer via regulating PTEN/AKT signaling pathway.Cancer Cell Int. 2019 Nov 8;19:283. doi: 10.1186/s12935-019-0998-4. eCollection 2019.
323 Expression and Significance of TRIM 28 in Squamous Carcinoma of Esophagus.Pathol Oncol Res. 2019 Oct;25(4):1645-1652. doi: 10.1007/s12253-018-0558-6. Epub 2018 Nov 27.
324 Study on the role of transient receptor potential C6 channels in esophageal squamous cell carcinoma radiosensitivity.J Thorac Dis. 2017 Oct;9(10):3802-3809. doi: 10.21037/jtd.2017.09.108.
325 Transient Receptor Potential Melastatin 7 as an Independent Prognostic Factor in Human Esophageal Squamous Cell Carcinoma.Anticancer Res. 2017 Mar;37(3):1161-1167. doi: 10.21873/anticanres.11429.
326 The TRPV2 cation channels: from urothelial cancer invasiveness to glioblastoma multiforme interactome signature.Lab Invest. 2020 Feb;100(2):186-198. doi: 10.1038/s41374-019-0333-7. Epub 2019 Oct 25.
327 TRPV6 plays a new role in predicting survival of patients with esophageal squamous cell carcinoma.Diagn Pathol. 2016 Jan 27;11:14. doi: 10.1186/s13000-016-0457-7.
328 Identification of distinct gene expression profiles between esophageal squamous cell carcinoma and adjacent normal epithelial tissues.Tohoku J Exp Med. 2012 Apr;226(4):301-11. doi: 10.1620/tjem.226.301.
329 TUSC2P suppresses the tumor function of esophageal squamous cell carcinoma by regulating TUSC2 expression and correlates with disease prognosis.BMC Cancer. 2018 Sep 15;18(1):894. doi: 10.1186/s12885-018-4804-9.
330 Thymidine phosphorylase and angiogenesis in early stage esophageal squamous cell carcinoma.Esophagus. 2018 Jan;15(1):19-26. doi: 10.1007/s10388-017-0588-2. Epub 2017 Jul 24.
331 Deubiquitylatinase inhibitor b-AP15 induces c-Myc-Noxa-mediated apoptosis in esophageal squamous cell carcinoma.Apoptosis. 2019 Oct;24(9-10):826-836. doi: 10.1007/s10495-019-01561-9.
332 The predictive role of E2-EPF ubiquitin carrier protein in esophageal squamous cell carcinoma.J Mol Med (Berl). 2009 Mar;87(3):307-20. doi: 10.1007/s00109-008-0430-3. Epub 2008 Dec 16.
333 Intensive expression of UNC-51-like kinase 1 is a novel biomarker of poor prognosis in patients with esophageal squamous cell carcinoma.Cancer Sci. 2011 Aug;102(8):1568-75. doi: 10.1111/j.1349-7006.2011.01964.x. Epub 2011 May 31.
334 High orotate phosphoribosyltransferase gene expression predicts complete response to chemoradiotherapy in patients with squamous cell carcinoma of the esophagus.Oncology. 2009;76(5):342-9. doi: 10.1159/000209964. Epub 2009 Mar 23.
335 Targeting the overexpressed USP7 inhibits esophageal squamous cell carcinoma cell growth by inducing NOXA-mediated apoptosis.Mol Carcinog. 2019 Jan;58(1):42-54. doi: 10.1002/mc.22905. Epub 2018 Sep 21.
336 Targeting valosin-containing protein enhances the efficacy of radiation therapy in esophageal squamous cell carcinoma.Cancer Sci. 2019 Nov;110(11):3464-3475. doi: 10.1111/cas.14184. Epub 2019 Sep 13.
337 WASH overexpression enhances cancer stem cell properties and correlates with poor prognosis of esophageal carcinoma.Cancer Sci. 2017 Dec;108(12):2358-2365. doi: 10.1111/cas.13400. Epub 2017 Sep 26.
338 Transcriptional and posttranscriptional regulation of HOXA13 by lncRNA HOTTIP facilitates tumorigenesis and metastasis in esophageal squamous carci... Oncogene. 2017 Sep 21;36(38):5392-5406.
339 Targeting TRIM3 deletion-induced tumor-associated lymphangiogenesis prohibits lymphatic metastasis in esophageal squamous cell carcinoma.Oncogene. 2019 Apr;38(15):2736-2749. doi: 10.1038/s41388-018-0621-5. Epub 2018 Dec 12.
340 X-linked inhibitor of apoptosis protein accelerates migration by inducing epithelial-mesenchymal transition through TGF- signaling pathway in esophageal cancer cells.Cell Biosci. 2019 Sep 18;9:76. doi: 10.1186/s13578-019-0338-3. eCollection 2019.
341 Clinical values of Ku80 upregulation in superficial esophageal squamous cell carcinoma.Cancer Med. 2018 Apr;7(4):1006-1018. doi: 10.1002/cam4.1314. Epub 2018 Mar 13.
342 Correlation of CT texture changes with treatment response during radiation therapy for esophageal cancer: An exploratory study.PLoS One. 2019 Sep 26;14(9):e0223140. doi: 10.1371/journal.pone.0223140. eCollection 2019.
343 Using proteomic approach to identify tumor-associated proteins as biomarkers in human esophageal squamous cell carcinoma.J Proteome Res. 2011 Jun 3;10(6):2863-72. doi: 10.1021/pr200141c. Epub 2011 May 3.
344 ATF3 functions as a novel tumor suppressor with prognostic significance in esophageal squamous cell carcinoma.Oncotarget. 2014 Sep 30;5(18):8569-82. doi: 10.18632/oncotarget.2322.
345 Combinatorial use of bone morphogenetic protein 6, noggin and SOST significantly predicts cancer progression.Cancer Sci. 2012 Jun;103(6):1145-54. doi: 10.1111/j.1349-7006.2012.02252.x. Epub 2012 Apr 3.
346 Expression of Hsp90 and cyclin B1 were related to prognosis of esophageal squamous cell carcinoma and keratin pearl formation.Int J Clin Exp Pathol. 2014 Mar 15;7(4):1544-52. eCollection 2014.
347 Overexpression of CDC25B and LAMC2 mRNA and protein in esophageal squamous cell carcinomas and premalignant lesions in subjects from a high-risk population in China.Cancer Epidemiol Biomarkers Prev. 2008 Jun;17(6):1424-35. doi: 10.1158/1055-9965.EPI-06-0666.
348 EGF-induced C/EBP participates in EMT by decreasing the expression of miR-203 in esophageal squamous cell carcinoma cells.J Cell Sci. 2014 Sep 1;127(Pt 17):3735-44. doi: 10.1242/jcs.148759. Epub 2014 Jul 2.
349 Prognostic significance of desmoglein 2 and desmoglein 3 in esophageal squamous cell carcinoma.Asian Pac J Cancer Prev. 2014;15(2):871-6. doi: 10.7314/apjcp.2014.15.2.871.
350 The 4E-BP1/eIF4E ratio is a determinant for rapamycin response in esophageal cancer cells.J Thorac Cardiovasc Surg. 2015 Jan;149(1):378-85. doi: 10.1016/j.jtcvs.2014.09.047. Epub 2014 Sep 18.
351 Stemness and chemotherapeutic drug resistance induced by EIF5A2 overexpression in esophageal squamous cell carcinoma.Oncotarget. 2015 Sep 22;6(28):26079-89. doi: 10.18632/oncotarget.4581.
352 Down-regulation of EphB4 phosphorylation is necessary for esophageal squamous cell carcinoma tumorigenecity.Tumour Biol. 2014 Jul;35(7):7225-32. doi: 10.1007/s13277-014-1955-4. Epub 2014 Apr 27.
353 Ets2 knockdown inhibits tumorigenesis in esophageal squamous cell carcinoma in vivo and in vitro.Oncotarget. 2016 Sep 20;7(38):61458-61468. doi: 10.18632/oncotarget.11369.
354 Analysis of HAX-1 gene expression in esophageal squamous cell carcinoma.Diagn Pathol. 2013 Mar 25;8:47. doi: 10.1186/1746-1596-8-47.
355 TGF-1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma.Oncotarget. 2015 Feb 10;6(4):2120-33. doi: 10.18632/oncotarget.2940.
356 The impact of pri-miR-218 rs11134527 on the risk and prognosis of patients with esophageal squamous cell carcinoma.Int J Clin Exp Pathol. 2014 Aug 15;7(9):6206-12. eCollection 2014.
357 MSH2 promoter hypermethylation in circulating tumor DNA is a valuable predictor of disease-free survival for patients with esophageal squamous cell carcinoma.Eur J Surg Oncol. 2012 Apr;38(4):326-32. doi: 10.1016/j.ejso.2012.01.008. Epub 2012 Jan 23.
358 Cyr61 promotes CD204 expression and the migration of macrophages via MEK/ERK pathway in esophageal squamous cell carcinoma.Cancer Med. 2015 Mar;4(3):437-46. doi: 10.1002/cam4.401. Epub 2015 Jan 26.
359 Overexpression of SRC-3 promotes esophageal squamous cell carcinoma aggressiveness by enhancing cell growth and invasiveness.Cancer Med. 2016 Dec;5(12):3500-3511. doi: 10.1002/cam4.884. Epub 2016 Oct 26.
360 The histone demethylase PHF8 is an oncogenic protein in human non-small cell lung cancer.Biochem Biophys Res Commun. 2014 Aug 15;451(1):119-25. doi: 10.1016/j.bbrc.2014.07.076. Epub 2014 Jul 24.
361 The telomere/telomerase binding factor PinX1 is a new target to improve the radiotherapy effect of oesophageal squamous cell carcinomas.J Pathol. 2013 Apr;229(5):765-74. doi: 10.1002/path.4163. Epub 2013 Feb 22.
362 Overexpression of phospholipase A2 Group IIA in esophageal squamous cell carcinoma and association with cyclooxygenase-2 expression.Asian Pac J Cancer Prev. 2014;15(21):9417-21. doi: 10.7314/apjcp.2014.15.21.9417.
363 Downregulated expression of PTK6 is correlated with poor survival in esophageal squamous cell carcinoma.Med Oncol. 2014 Dec;31(12):317. doi: 10.1007/s12032-014-0317-9. Epub 2014 Nov 7.
364 Phosphatase of regenerating liver-3 as a convergent therapeutic target for lymph node metastasis in esophageal squamous cell carcinoma.Int J Cancer. 2010 Aug 1;127(3):543-54. doi: 10.1002/ijc.25082.
365 Abnormalities of chromosome 17 in oesophageal cancer.J Clin Pathol. 2007 Sep;60(9):990-4. doi: 10.1136/jcp.2006.042416. Epub 2006 Oct 17.
366 TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma.Biomed Pharmacother. 2015 Aug;74:71-6. doi: 10.1016/j.biopha.2015.07.004. Epub 2015 Aug 3.
367 TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma.J Gastroenterol. 2014 Aug;49(8):1231-40. doi: 10.1007/s00535-013-0870-6. Epub 2013 Aug 21.
368 TRAF6 promoted the metastasis of esophageal squamous cell carcinoma.Tumour Biol. 2014 Jan;35(1):715-21. doi: 10.1007/s13277-013-1098-z. Epub 2013 Sep 13.
369 Elevated expression of the nuclear export protein, Crm1 (exportin 1), associates with human oesophageal squamous cell carcinoma.Oncol Rep. 2014 Aug;32(2):730-8. doi: 10.3892/or.2014.3231. Epub 2014 Jun 4.
370 Long noncoding RNA lnc-ABCA12-3 promotes cell migration, invasion, and proliferation by regulating fibronectin 1 in esophageal squamous cell carcinoma.J Cell Biochem. 2020 Feb;121(2):1374-1387. doi: 10.1002/jcb.29373. Epub 2019 Sep 12.
371 NGALR is overexpressed and regulated by hypomethylation in esophageal squamous cell carcinoma.Clin Cancer Res. 2008 Dec 1;14(23):7674-81. doi: 10.1158/1078-0432.CCR-08-0420.
372 Protein-coding genes combined with long non-coding RNAs predict prognosis in esophageal squamous cell carcinoma patients as a novel clinical multi-dimensional signature.Mol Biosyst. 2016 Oct 18;12(11):3467-3477. doi: 10.1039/c6mb00585c.
373 Discovery of deregulation of zinc homeostasis and its associated genes in esophageal squamous cell carcinoma using cDNA microarray.Int J Cancer. 2007 Jan 15;120(2):230-42. doi: 10.1002/ijc.22246.
374 Knockdown of zinc transporter ZIP5 (SLC39A5) expression significantly inhibits human esophageal cancer progression.Oncol Rep. 2015 Sep;34(3):1431-9. doi: 10.3892/or.2015.4097. Epub 2015 Jul 1.
375 Expression and role of anion exchanger 1 in esophageal squamous cell carcinoma.Oncotarget. 2017 Mar 14;8(11):17921-17935. doi: 10.18632/oncotarget.14900.
376 Anion exchanger 2 suppresses cellular movement and has prognostic significance in esophageal squamous cell carcinoma.Oncotarget. 2018 May 25;9(40):25993-26006. doi: 10.18632/oncotarget.25417. eCollection 2018 May 25.
377 Prognostic significance of SLC9A9 in patients with resectable esophageal squamous cell carcinoma.Tumour Biol. 2015 Sep;36(9):6797-803. doi: 10.1007/s13277-015-3392-4. Epub 2015 Apr 3.
378 No role for glutathione S-transferase genotypes in Caucasian esophageal squamous cell or adenocarcinoma etiology: an European case-control study.BMC Gastroenterol. 2013 Jun 3;13:97. doi: 10.1186/1471-230X-13-97.
379 Interaction Between Prediabetes and the ABO Blood Types in Predicting Postsurgical Esophageal Squamous Cell Carcinoma-Specific Mortality: The FIESTA Study.Front Oncol. 2018 Oct 23;8:461. doi: 10.3389/fonc.2018.00461. eCollection 2018.
380 Alcohol metabolism and oesophageal cancer: a systematic review of the evidence.Carcinogenesis. 2017 Sep 1;38(9):859-872. doi: 10.1093/carcin/bgx067.
381 Expression of ACP6 is an independent prognostic factor for poor survival in patients with esophageal squamous cell carcinoma.Oncol Rep. 2006 Jun;15(6):1551-5.
382 ACSS2/AMPK/PCNA pathwaydriven proliferation and chemoresistance of esophageal squamous carcinoma cells under nutrient stress.Mol Med Rep. 2019 Dec;20(6):5286-5296. doi: 10.3892/mmr.2019.10735. Epub 2019 Oct 9.
383 Construction of a risk model for the development of metachronous squamous cell carcinoma after endoscopic resection of esopahageal squamous cell carcinoma.Esophagus. 2019 Apr;16(2):141-146. doi: 10.1007/s10388-018-0643-7. Epub 2018 Sep 1.
384 Impact of alcohol dehydrogenase gene 4 polymorphisms on esophageal squamous cell carcinoma risk in a Chinese population.PLoS One. 2015 Jun 3;10(6):e0127304. doi: 10.1371/journal.pone.0127304. eCollection 2015.
385 Alcohol Intake Interacts with Functional Genetic Polymorphisms of Aldehyde Dehydrogenase (ALDH2) and Alcohol Dehydrogenase (ADH) to Increase Esophageal Squamous Cell Cancer Risk.J Thorac Oncol. 2019 Apr;14(4):712-725. doi: 10.1016/j.jtho.2018.12.023. Epub 2019 Jan 9.
386 The roles of AKR1C1 and AKR1C2 in ethyl-3,4-dihydroxybenzoate induced esophageal squamous cell carcinoma cell death.Oncotarget. 2016 Apr 19;7(16):21542-55. doi: 10.18632/oncotarget.7775.
387 Microsatellite instability in esophageal squamous cell carcinoma is not associated with hMLH1 promoter hypermethylation.Pathol Int. 2003 May;53(5):270-6. doi: 10.1046/j.1440-1827.2003.01478.x.
388 Associations of carboxypeptidase 4 with ALDH1A1 expression and their prognostic value in esophageal squamous cell carcinoma.Dis Esophagus. 2017 Jun 1;30(6):1-5. doi: 10.1093/dote/dox011.
389 Pathway, in silico and tissue-specific expression quantitative analyses of oesophageal squamous cell carcinoma genome-wide association studies data.Int J Epidemiol. 2016 Feb;45(1):206-20. doi: 10.1093/ije/dyv294. Epub 2015 Dec 3.
390 Single Nucleotide Polymorphisms in the PTPN1 Gene Are Associated with Susceptibility to Esophageal Squamous Cell Carcinoma: A Case-Control Study in Inner Mongolia, China.Genet Test Mol Biomarkers. 2017 May;21(5):305-311. doi: 10.1089/gtmb.2016.0194. Epub 2017 Mar 13.
391 Glutathione S-transferase omega 2 regulates cell growth and the expression of E-cadherin via post-transcriptional down-regulation of -catenin in human esophageal squamous cells.Carcinogenesis. 2020 Jul 14;41(7):875-886. doi: 10.1093/carcin/bgz189.
392 Overexpression of leucine aminopeptidase 3 contributes to malignant development of human esophageal squamous cell carcinoma.J Mol Histol. 2014 Jun;45(3):283-92. doi: 10.1007/s10735-014-9566-3. Epub 2014 Jan 30.
393 NAT1 and NAT2 genetic polymorphisms and environmental exposure as risk factors for oesophageal squamous cell carcinoma: a case-control study.BMC Cancer. 2015 Mar 18;15:150. doi: 10.1186/s12885-015-1105-4.
394 The value of the combination of hemoglobin, albumin, lymphocyte and platelet in predicting platinum-based chemoradiotherapy response in male patients with esophageal squamous cell carcinoma.Int Immunopharmacol. 2017 May;46:75-79. doi: 10.1016/j.intimp.2017.02.027. Epub 2017 Mar 6.
395 Downregulation of nicotinamide N-methyltransferase inhibits migration and epithelial-mesenchymal transition of esophageal squamous cell carcinoma via Wnt/-catenin pathway.Mol Cell Biochem. 2019 Oct;460(1-2):93-103. doi: 10.1007/s11010-019-03573-0. Epub 2019 Jul 5.
396 Genotypes of CYP1A1,SULT1A1 and SULT1A2 and risk of squamous cell carcinoma of esophagus: outcome of a case-control study from Kashmir, India.Dis Esophagus. 2016 Nov;29(8):937-943. doi: 10.1111/dote.12427. Epub 2015 Oct 12.
397 High enzyme activity UGT1A1 or low activity UGT1A8 and UGT2B4 genotypes increase esophageal cancer risk.Int J Oncol. 2012 Jun;40(6):1789-96. doi: 10.3892/ijo.2012.1385. Epub 2012 Feb 22.
398 UGT2B17 and miR-224 contribute to hormone dependency trends in adenocarcinoma and squamous cell carcinoma of esophagus.Biosci Rep. 2019 Jul 5;39(7):BSR20190472. doi: 10.1042/BSR20190472. Print 2019 Jul 31.
399 Spatially resolved metabolomics to discover tumor-associated metabolic alterations.Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):52-57. doi: 10.1073/pnas.1808950116. Epub 2018 Dec 17.
400 Overexpression of Phosphoserine Aminotransferase 1 (PSAT1) Predicts Poor Prognosis and Associates with Tumor Progression in Human Esophageal Squamous Cell Carcinoma.Cell Physiol Biochem. 2016;39(1):395-406. doi: 10.1159/000445633. Epub 2016 Jul 4.
401 The biogenesis and biological functions of circular RNAs and their molecular diagnostic values in cancers.J Clin Lab Anal. 2020 Jan;34(1):e23049. doi: 10.1002/jcla.23049. Epub 2019 Sep 25.
402 E3B1/ABI-1 isoforms are down-regulated in cancers of human gastrointestinal tract.Dis Markers. 2012;32(4):273-9. doi: 10.3233/DMA-2011-0881.
403 Effects of JWA, XRCC1 and BRCA1 mRNA expression on molecular staging for personalized therapy in patients with advanced esophageal squamous cell carcinoma.BMC Cancer. 2015 Apr 30;15:331. doi: 10.1186/s12885-015-1364-0.
404 Overexpression of the DEC1 protein induces senescence in vitro and is related to better survival in esophageal squamous cell carcinoma.PLoS One. 2012;7(7):e41862. doi: 10.1371/journal.pone.0041862. Epub 2012 Jul 23.
405 A genetic variant in CDKN2A/2B locus was associated with poor prognosis in patients with esophageal squamous cell carcinoma.J Cell Physiol. 2019 Apr;234(4):5070-5076. doi: 10.1002/jcp.27310. Epub 2018 Sep 21.
406 The identification of two regulatory ESCC susceptibility genetic variants in the TERT-CLPTM1L loci.Oncotarget. 2016 Feb 2;7(5):5495-506. doi: 10.18632/oncotarget.6747.
407 Integrative genomics analysis of hub genes and their relationship with prognosis and signaling pathways in esophageal squamous cell carcinoma.Mol Med Rep. 2019 Oct;20(4):3649-3660. doi: 10.3892/mmr.2019.10608. Epub 2019 Aug 23.
408 Anti-FIRexon2, a splicing variant form of PUF60, autoantibody is detected in the sera of esophageal squamous cell carcinoma.Cancer Sci. 2019 Jun;110(6):2004-2013. doi: 10.1111/cas.14024. Epub 2019 May 20.
409 miR-338-5p inhibits cell proliferation, colony formation, migration and cisplatin resistance in esophageal squamous cancer cells by targeting FERMT2.Carcinogenesis. 2019 Jul 20;40(7):883-892. doi: 10.1093/carcin/bgy189.
410 Identification of cytokeratin subspecies altered in rat experimental esophageal tumors by subtractive cloning.Cancer Lett. 1996 Nov 12;108(1):119-27. doi: 10.1016/s0304-3835(96)04403-5.
411 Mitotic checkpoint genes, hsMAD2 and BubR1, in oesophageal squamous cancer cells and their association with 5-fluorouracil and cisplatin-based radiochemotherapy. Clin Oncol (R Coll Radiol). 2008 Oct;20(8):639-46. doi: 10.1016/j.clon.2008.06.010. Epub 2008 Aug 8.
412 Prognostic and predictive role of COX-2, XRCC1 and RASSF1 expression in patients with esophageal squamous cell carcinoma receiving radiotherapy.Oncol Lett. 2017 Apr;13(4):2549-2556. doi: 10.3892/ol.2017.5780. Epub 2017 Feb 24.
413 Correlation Between Biomarker Candidate Proteins with the Effect of Neoadjuvant Chemoradiation Therapy on Esophageal Squamous Cell Carcinoma.Ann Surg Oncol. 2018 Feb;25(2):449-455. doi: 10.1245/s10434-017-6271-y. Epub 2017 Nov 29.
414 Enhanced Expression of miR-425 Promotes Esophageal Squamous Cell Carcinoma Tumorigenesis by Targeting SMAD2.J Genet Genomics. 2015 Nov 20;42(11):601-611. doi: 10.1016/j.jgg.2015.09.010. Epub 2015 Oct 9.
415 Confirmation of the prognostic value of pretherapeutic tumor SUR and MTV in patients with esophageal squamous cell carcinoma.Eur J Nucl Med Mol Imaging. 2019 Jul;46(7):1485-1494. doi: 10.1007/s00259-019-04307-6. Epub 2019 Apr 4.
416 Entinostat reverses cisplatin resistance in esophageal squamous cell carcinoma via down-regulation of multidrug resistance gene 1.Cancer Lett. 2018 Feb 1;414:294-300. doi: 10.1016/j.canlet.2017.10.023. Epub 2017 Dec 5.
417 Targeted therapy of the AKT kinase inhibits esophageal squamous cell carcinoma growth in vitro and in vivo.Int J Cancer. 2019 Aug 15;145(4):1007-1019. doi: 10.1002/ijc.32285. Epub 2019 Apr 3.
418 Role of MAML1 in targeted therapy against the esophageal cancer stem cells.J Transl Med. 2019 Apr 16;17(1):126. doi: 10.1186/s12967-019-1876-5.
419 FAM134B promotes esophageal squamous cell carcinoma in vitro and its correlations with clinicopathologic features.Hum Pathol. 2019 May;87:1-10. doi: 10.1016/j.humpath.2018.11.033. Epub 2019 Feb 20.
420 SOX17 overexpression sensitizes chemoradiation response in esophageal cancer by transcriptional down-regulation of DNA repair and damage response genes.J Biomed Sci. 2019 Feb 18;26(1):20. doi: 10.1186/s12929-019-0510-4.
421 Association of MTHFR C677T and SHMT(1) C1420T with susceptibility to ESCC and GCA in a high incident region of Northern China.Cancer Causes Control. 2007 Mar;18(2):143-52. doi: 10.1007/s10552-006-0097-4. Epub 2007 Jan 6.
422 Clinical significance of SPRR1A expression in progesterone receptor-positive breast cancer.Tumour Biol. 2015 Apr;36(4):2601-5. doi: 10.1007/s13277-014-2879-8. Epub 2014 Nov 26.
423 Decitabine enhances tumor recognition by T cells through upregulating the MAGE-A3 expression in esophageal carcinoma.Biomed Pharmacother. 2019 Apr;112:108632. doi: 10.1016/j.biopha.2019.108632. Epub 2019 Feb 20.
424 Low expression level of ASK1-interacting protein-1 correlated with tumor angiogenesis and poor survival in patients with esophageal squamous cell cancer.Onco Targets Ther. 2018 Nov 1;11:7699-7707. doi: 10.2147/OTT.S178131. eCollection 2018.
425 Acyl-CoA dehydrogenase long chain expression is associated with esophageal squamous cell carcinoma progression and poor prognosis.Onco Targets Ther. 2018 Oct 31;11:7643-7653. doi: 10.2147/OTT.S171963. eCollection 2018.
426 SOX2 antagonizes WWC1 to drive YAP1 activation in esophageal squamous cell carcinoma.Cancer Med. 2019 Nov;8(16):7055-7064. doi: 10.1002/cam4.2569. Epub 2019 Sep 27.
427 An ADAM12 and FAK positive feedback loop amplifies the interaction signal of tumor cells with extracellular matrix to promote esophageal cancer metastasis.Cancer Lett. 2018 May 28;422:118-128. doi: 10.1016/j.canlet.2018.02.031. Epub 2018 Feb 21.
428 Comprehensive bioinformatics analysis identifies lncRNA HCG22 as a migration inhibitor in esophageal squamous cell carcinoma.J Cell Biochem. 2020 Jan;121(1):468-481. doi: 10.1002/jcb.29218. Epub 2019 Jun 25.
429 Serial analysis of gene expression of esophageal squamous cell carcinoma: ADAMTS16 is upregulated in esophageal squamous cell carcinoma.Cancer Sci. 2010 Apr;101(4):1038-44. doi: 10.1111/j.1349-7006.2009.01477.x. Epub 2009 Dec 16.
430 ADAMTS-6 is a predictor of poor prognosis in patients with esophageal squamous cell carcinoma.Exp Mol Pathol. 2018 Apr;104(2):134-139. doi: 10.1016/j.yexmp.2018.02.004. Epub 2018 Feb 21.
431 Extracellular protease ADAMTS9 suppresses esophageal and nasopharyngeal carcinoma tumor formation by inhibiting angiogenesis.Cancer Res. 2010 Jul 1;70(13):5567-76. doi: 10.1158/0008-5472.CAN-09-4510. Epub 2010 Jun 15.
432 ADAR2 functions as a tumor suppressor via editing IGFBP7 in esophageal squamous cell carcinoma.Int J Oncol. 2017 Feb;50(2):622-630. doi: 10.3892/ijo.2016.3823. Epub 2016 Dec 29.
433 XB130 as an independent prognostic factor in human esophageal squamous cell carcinoma.Ann Surg Oncol. 2013 Sep;20(9):3140-50. doi: 10.1245/s10434-012-2474-4. Epub 2012 Jul 18.
434 Implications of Bit1 and AIF overexpressions in esophageal squamous cell carcinoma.Tumour Biol. 2014 Jan;35(1):519-27. doi: 10.1007/s13277-013-1073-8. Epub 2013 Aug 17.
435 Endogenous AJAP1 associates with the cytoskeleton and attenuates angiogenesis in endothelial cells.Biol Open. 2017 Jun 15;6(6):723-731. doi: 10.1242/bio.022335.
436 Comprehensive genomic analysis of Oesophageal Squamous Cell Carcinoma reveals clinical relevance.Sci Rep. 2017 Nov 10;7(1):15324. doi: 10.1038/s41598-017-14909-5.
437 Hypermethylation of the AKAP12 promoter is a biomarker of Barrett's-associated esophageal neoplastic progression.Cancer Epidemiol Biomarkers Prev. 2008 Jan;17(1):111-7. doi: 10.1158/1055-9965.EPI-07-0407.
438 Down-regulation of Rictor enhances cell sensitivity to PI3K inhibitor LY294002 by blocking mTORC2-medicated phosphorylation of Akt/PRAS40 in esophageal squamous cell carcinoma.Biomed Pharmacother. 2018 Oct;106:1348-1356. doi: 10.1016/j.biopha.2018.07.075. Epub 2018 Jul 23.
439 The ALDH7A1 genetic polymorphisms contribute to development of esophageal squamous cell carcinoma.Tumour Biol. 2014 Dec;35(12):12665-70. doi: 10.1007/s13277-014-2590-9. Epub 2014 Sep 12.
440 Identification of putative target genes for amplification within 11q13.2 and 3q27.1 in esophageal squamous cell carcinoma.Clin Transl Oncol. 2014 Jul;16(7):606-15. doi: 10.1007/s12094-013-1124-z. Epub 2013 Nov 8.
441 Expression, Function, and Prognostic Value of MAGE-D4 Protein in Esophageal Squamous Cell Carcinoma.Anticancer Res. 2019 Nov;39(11):6015-6023. doi: 10.21873/anticanres.13807.
442 APOBEC3B is an enzymatic source of molecular alterations in esophageal squamous cell carcinoma.Med Oncol. 2016 Mar;33(3):26. doi: 10.1007/s12032-016-0739-7. Epub 2016 Feb 15.
443 Genome-wide analyses of long non-coding RNA expression profiles and functional network analysis in esophageal squamous cell carcinoma.Sci Rep. 2019 Jun 24;9(1):9162. doi: 10.1038/s41598-019-45493-5.
444 Identification of genomic alterations in oesophageal squamous cell cancer.Nature. 2014 May 1;509(7498):91-5. doi: 10.1038/nature13176. Epub 2014 Mar 16.
445 Aberrant nuclear localization of beta-catenin without genetic alterations in beta-catenin or Axin genes in esophageal cancer.World J Surg Oncol. 2007 Feb 19;5:21. doi: 10.1186/1477-7819-5-21.
446 Adenosine-to-inosine RNA editing mediated by ADARs in esophageal squamous cell carcinoma.Cancer Res. 2014 Feb 1;74(3):840-51. doi: 10.1158/0008-5472.CAN-13-2545. Epub 2013 Dec 3.
447 Role of intravoxel incoherent motion MRI in early assessment of the response of esophageal squamous cell carcinoma to chemoradiotherapy: A pilot study.J Magn Reson Imaging. 2018 Aug;48(2):349-358. doi: 10.1002/jmri.25934. Epub 2018 Jan 3.
448 IGFBP3 and BAG1 enhance radiation-induced apoptosis in squamous esophageal cancer cells.Biochem Biophys Res Commun. 2011 Jan 28;404(4):1070-5. doi: 10.1016/j.bbrc.2010.12.115. Epub 2010 Dec 30.
449 Expression of VRK1 and the downstream gene BANF1 in esophageal cancer.Biomed Pharmacother. 2017 May;89:1086-1091. doi: 10.1016/j.biopha.2017.02.095. Epub 2017 Mar 11.
450 An esophageal adenocarcinoma susceptibility locus at 9q22 also confers risk to esophageal squamous cell carcinoma by regulating the function of BARX1.Cancer Lett. 2018 May 1;421:103-111. doi: 10.1016/j.canlet.2018.02.019. Epub 2018 Feb 14.
451 High Expression of BCCIP Can Promote Proliferation of Esophageal Squamous Cell Carcinoma.Dig Dis Sci. 2017 Feb;62(2):387-395. doi: 10.1007/s10620-016-4382-0. Epub 2016 Dec 19.
452 Relationship between Egr-1 gene expression and apoptosis in esophageal carcinoma and precancerous lesions.World J Gastroenterol. 2002 Dec;8(6):971-5. doi: 10.3748/wjg.v8.i6.971.
453 Low expression of BEX1 predicts poor prognosis in patients with esophageal squamous cell cancer.Oncol Rep. 2018 Nov;40(5):2778-2787. doi: 10.3892/or.2018.6647. Epub 2018 Aug 17.
454 DEC2 expression antagonizes cisplatininduced apoptosis in human esophageal squamous cell carcinoma.Mol Med Rep. 2017 Jul;16(1):43-48. doi: 10.3892/mmr.2017.6571. Epub 2017 May 11.
455 Methylation decreases the Bin1 tumor suppressor in ESCC and restoration by decitabine inhibits the epithelial mesenchymal transition.Oncotarget. 2017 Mar 21;8(12):19661-19673. doi: 10.18632/oncotarget.14914.
456 Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma.Oncotarget. 2014 Aug 30;5(16):7183-97. doi: 10.18632/oncotarget.2293.
457 MicroRNA-125b inhibits cell proliferation and induces cell apoptosis in esophageal squamous cell carcinoma by targeting BMF.Oncol Rep. 2018 Jul;40(1):61-72. doi: 10.3892/or.2018.6413. Epub 2018 May 2.
458 Novel long noncoding RNA NMR promotes tumor progression via NSUN2 and BPTF in esophageal squamous cell carcinoma.Cancer Lett. 2018 Aug 28;430:57-66. doi: 10.1016/j.canlet.2018.05.013. Epub 2018 May 12.
459 BRCA1-Associated Protein Increases Invasiveness of Esophageal Squamous Cell Carcinoma.Gastroenterology. 2017 Nov;153(5):1304-1319.e5. doi: 10.1053/j.gastro.2017.07.042. Epub 2017 Aug 2.
460 BRF2 as a promising indicator for radical lymph-node dissection surgery in patients with cN0 squamous cell carcinoma of the middle thoracic esophagus.Surg Today. 2019 Feb;49(2):158-169. doi: 10.1007/s00595-018-1711-2. Epub 2018 Sep 4.
461 Clinical implication of elevated human cervical cancer oncogene-1 expression in esophageal squamous cell carcinoma.J Histochem Cytochem. 2012 Jul;60(7):512-20. doi: 10.1369/0022155412444437. Epub 2012 Apr 17.
462 The overexpression of DBC1 in esophageal squamous cell carcinoma correlates with poor prognosis.Histol Histopathol. 2012 Jan;27(1):49-58. doi: 10.14670/HH-27.49.
463 TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-B signaling.Nat Commun. 2018 Apr 12;9(1):1423. doi: 10.1038/s41467-018-03716-9.
464 Gene set enrichment analysis and meta-analysis to identify six key genes regulating and controlling the prognosis of esophageal squamous cell carcinoma.J Thorac Dis. 2018 Oct;10(10):5714-5726. doi: 10.21037/jtd.2018.09.55.
465 Clinic implication of MUC1 O-glycosylation and C1GALT1 in esophagus squamous cell carcinoma.Sci China Life Sci. 2018 Nov;61(11):1389-1395. doi: 10.1007/s11427-017-9345-7. Epub 2018 Aug 1.
466 CADM1 mRNA expression and clinicopathological significance in esophageal squamous cell carcinoma tissue.Genet Mol Res. 2017 May 10;16(2). doi: 10.4238/gmr16029178.
467 The CADM2/Akt pathway is involved in the inhibitory effect of miR-21-5p downregulation on proliferation and apoptosis in esophageal squamous cell carcinoma cells.Chem Biol Interact. 2018 May 25;288:76-82. doi: 10.1016/j.cbi.2018.04.021. Epub 2018 Apr 19.
468 Downregulated expression of the cyclase-associated protein 1 (CAP1) reduces migration in esophageal squamous cell carcinoma.Jpn J Clin Oncol. 2013 Sep;43(9):856-64. doi: 10.1093/jjco/hyt093. Epub 2013 Jul 30.
469 Oncogene GAEC1 regulates CAPN10 expression which predicts survival in esophageal squamous cell carcinoma.World J Gastroenterol. 2013 May 14;19(18):2772-80. doi: 10.3748/wjg.v19.i18.2772.
470 Genome-wide ChIP-seq data with a transcriptome analysis reveals the groups of genes regulated by histone demethylase LSD1 inhibition in esophageal squamous cell carcinoma cells.Oncol Lett. 2019 Jul;18(1):872-881. doi: 10.3892/ol.2019.10350. Epub 2019 May 13.
471 Capn4 promotes esophageal squamous cell carcinoma metastasis by regulating ZEB1 through the Wnt/-catenin signaling pathway.Thorac Cancer. 2019 Jan;10(1):24-32. doi: 10.1111/1759-7714.12893. Epub 2018 Nov 15.
472 Overexpression of calcyphosine is associated with poor prognosis in esophageal squamous cell carcinoma.Oncol Lett. 2017 Nov;14(5):6231-6237. doi: 10.3892/ol.2017.6973. Epub 2017 Sep 15.
473 The overexpression of caveolin-1 and caveolin-2 correlates with a poor prognosis and tumor progression in esophageal squamous cell carcinoma.Oncol Rep. 2007 Sep;18(3):601-9.
474 CBX8 promotes tumorigenesis and confers radioresistance in esophageal squamous cell carcinoma cells through targeting APAF1.Gene. 2019 Aug 30;711:143949. doi: 10.1016/j.gene.2019.143949. Epub 2019 Jun 28.
475 Overexpression of Coiled-Coil Domain-Containing Protein 34 (CCDC34) and its Correlation with Angiogenesis in Esophageal Squamous Cell Carcinoma.Med Sci Monit. 2018 Feb 3;24:698-705. doi: 10.12659/msm.908335.
476 Clinical significance of sperm protein 17 expression and immunogenicity in esophageal cancer.Int J Cancer. 2007 Apr 15;120(8):1739-47. doi: 10.1002/ijc.22463.
477 Short tandem repeat polymorphism in a novel esophageal cancer-related gene (ECRG2) implicates susceptibility to esophageal cancer in Chinese population.Int J Cancer. 2004 Jan 10;108(2):232-6. doi: 10.1002/ijc.11560.
478 Genome-wide gene expression profile analyses identify CTTN as a potential prognostic marker in esophageal cancer.PLoS One. 2014 Feb 14;9(2):e88918. doi: 10.1371/journal.pone.0088918. eCollection 2014.
479 A truncated splice variant of human lysyl oxidase-like 2 promotes migration and invasion in esophageal squamous cell carcinoma.Int J Biochem Cell Biol. 2016 Jun;75:85-98. doi: 10.1016/j.biocel.2016.04.003. Epub 2016 Apr 8.
480 MCP2 activates NF-B signaling pathway promoting the migration and invasion of ESCC cells.Cell Biol Int. 2018 Mar;42(3):365-372. doi: 10.1002/cbin.10909. Epub 2017 Nov 22.
481 WISP2 exhibits its potential antitumor activity via targeting ERK and E-cadherin pathways in esophageal cancer cells.J Exp Clin Cancer Res. 2019 Feb 26;38(1):102. doi: 10.1186/s13046-019-1108-0.
482 Cyclin A1 is associated with poor prognosis in oesophageal squamous cell carcinoma.Oncol Lett. 2019 Jul;18(1):706-712. doi: 10.3892/ol.2019.10377. Epub 2019 May 20.
483 miR-516b functions as a tumor suppressor by directly modulating CCNG1 expression in esophageal squamous cell carcinoma.Biomed Pharmacother. 2018 Oct;106:1650-1660. doi: 10.1016/j.biopha.2018.07.074. Epub 2018 Jul 29.
484 Combination of c-reactive protein and squamous cell carcinoma antigen in predicting postoperative prognosis for patients with squamous cell carcinoma of the esophagus.Oncotarget. 2017 Jun 27;8(38):63132-63139. doi: 10.18632/oncotarget.18667. eCollection 2017 Sep 8.
485 Chaperonin-containing Tcomplex protein 1 subunit 8 promotes cell migration and invasion in human esophageal squamous cell carcinoma by regulating -actin and -tubulin expression.Int J Oncol. 2018 Jun;52(6):2021-2030. doi: 10.3892/ijo.2018.4335. Epub 2018 Mar 27.
486 Impact of tumor-infiltrating LAMP-3 dendritic cells on the prognosis of esophageal squamous cell carcinoma.Esophagus. 2019 Oct;16(4):333-344. doi: 10.1007/s10388-019-00669-w. Epub 2019 Apr 9.
487 CD82/KAI1 inhibits invasion and metastasis of esophageal squamous cell carcinoma via TGF-1.Eur Rev Med Pharmacol Sci. 2018 Sep;22(18):5928-5937. doi: 10.26355/eurrev_201809_15922.
488 miR-107 functions as a tumor suppressor in human esophageal squamous cell carcinoma and targets Cdc42.Oncol Rep. 2017 May;37(5):3116-3127. doi: 10.3892/or.2017.5546. Epub 2017 Apr 3.
489 Chromosomal aneuploidies and combinational fluorescence in situ hybridization probe panels are useful for predicting prognosis for esophageal squamous cell carcinoma.J Gastroenterol. 2015 Feb;50(2):155-66. doi: 10.1007/s00535-014-0961-z. Epub 2014 May 11.
490 Systematic cancer-testis gene expression analysis identified CDCA5 as a potential therapeutic target in esophageal squamous cell carcinoma.EBioMedicine. 2019 Aug;46:54-65. doi: 10.1016/j.ebiom.2019.07.030. Epub 2019 Jul 16.
491 Whole-Genome Sequencing Reveals Diverse Models of Structural Variations in Esophageal Squamous Cell Carcinoma.Am J Hum Genet. 2016 Feb 4;98(2):256-74. doi: 10.1016/j.ajhg.2015.12.013. Epub 2016 Jan 28.
492 Loss of CDCP1 expression promotes invasiveness and poor prognosis in esophageal squamous cell carcinoma.Ann Surg Oncol. 2014 Dec;21 Suppl 4:S640-7. doi: 10.1245/s10434-014-3740-4. Epub 2014 May 22.
493 The strong propensity of Cadherin-23 for aggregation inhibits cell migration.Mol Oncol. 2019 May;13(5):1092-1109. doi: 10.1002/1878-0261.12469. Epub 2019 Mar 19.
494 Overexpression of PFTK1 predicts resistance to chemotherapy in patients with oesophageal squamous cell carcinoma.Br J Cancer. 2012 Feb 28;106(5):947-54. doi: 10.1038/bjc.2012.35. Epub 2012 Feb 14.
495 Increased CDKL3 expression predicts poor prognosis and enhances malignant phenotypes in esophageal squamous cell carcinoma.J Cell Biochem. 2019 May;120(5):7174-7184. doi: 10.1002/jcb.27991. Epub 2018 Nov 1.
496 Single-nucleotide polymorphism-mass array reveals commonly deleted regions at 3p22 and 3p14.2 associate with poor clinical outcome in esophageal squamous cell carcinoma.Int J Cancer. 2008 Aug 15;123(4):826-30. doi: 10.1002/ijc.23577.
497 Let-7b-5p inhibits proliferation and motility in squamous cell carcinoma cells through negative modulation of KIAA1377.Cell Biol Int. 2019 Jun;43(6):634-641. doi: 10.1002/cbin.11136. Epub 2019 Apr 25.
498 Integrated analysis of differentially expressed genes in esophageal squamous cell carcinoma using bioinformatics.Neoplasma. 2018;65(4):523-531. doi: 10.4149/neo_2018_170708N470.
499 ALC1 knockdown enhances cisplatin cytotoxicity of esophageal squamous cell carcinoma cells by inhibition of glycolysis through PI3K/Akt pathway.Life Sci. 2019 Sep 1;232:116679. doi: 10.1016/j.lfs.2019.116679. Epub 2019 Jul 21.
500 A genetic variant in CHRNB3-CHRNA6 increases risk of esophageal squamous cell carcinoma in Chinese populations.Carcinogenesis. 2015 May;36(5):538-42. doi: 10.1093/carcin/bgv019. Epub 2015 Mar 30.
501 Long noncoding RNA MALAT1 affects the efficacy of radiotherapy for esophageal squamous cell carcinoma by regulating Cks1 expression.J Oral Pathol Med. 2017 Sep;46(8):583-590. doi: 10.1111/jop.12538. Epub 2017 Jun 5.
502 Clinical and biological impact of cyclin-dependent kinase subunit 2 in esophageal squamous cell carcinoma.Oncol Rep. 2014 May;31(5):1986-92. doi: 10.3892/or.2014.3062. Epub 2014 Mar 5.
503 CLDN1 induces autophagy to promote proliferation and metastasis of esophageal squamous carcinoma through AMPK/STAT1/ULK1 signaling.J Cell Physiol. 2020 Mar;235(3):2245-2259. doi: 10.1002/jcp.29133. Epub 2019 Sep 9.
504 Loss of PAR-3 protein expression is associated with invasion, lymph node metastasis, and poor survival in esophageal squamous cell carcinoma.Hum Pathol. 2017 Apr;62:134-140. doi: 10.1016/j.humpath.2017.01.009. Epub 2017 Feb 8.
505 Targeting CD47 Enhances the Efficacy of Anti-PD-1 and CTLA-4 in an Esophageal Squamous Cell Cancer Preclinical Model.Oncol Res. 2017 Nov 2;25(9):1579-1587. doi: 10.3727/096504017X14900505020895. Epub 2017 Mar 23.
506 Chemokine-like factor-like MARVEL transmembrane domain-containing 3 expression is associated with a favorable prognosis in esophageal squamous cell carcinoma.Oncol Lett. 2017 May;13(5):2982-2988. doi: 10.3892/ol.2017.5837. Epub 2017 Mar 10.
507 Chondromodulin-1 and vascular endothelial growth factor-A expression in esophageal squamous cell carcinoma: accelerator and brake theory for angiogenesis at the early stage of cancer progression.Esophagus. 2020 Apr;17(2):159-167. doi: 10.1007/s10388-019-00695-8. Epub 2019 Oct 8.
508 A decision tree-based combination of ezrin-interacting proteins to estimate the prognostic risk of patients with esophageal squamous cell carcinoma.Hum Pathol. 2017 Aug;66:115-125. doi: 10.1016/j.humpath.2017.06.003. Epub 2017 Jun 9.
509 The clinical significance of collagen family gene expression in esophageal squamous cell carcinoma.PeerJ. 2019 Oct 4;7:e7705. doi: 10.7717/peerj.7705. eCollection 2019.
510 Expression, regulation and targeting of receptor tyrosine kinases in esophageal squamous cell carcinoma.Mol Cancer. 2018 Feb 19;17(1):54. doi: 10.1186/s12943-018-0790-4.
511 Analysis of SPARC and TUBB3 as predictors for prognosis in esophageal squamous cell carcinoma receiving nab-paclitaxel plus cisplatin neoadjuvant chemotherapy: a prospective study.Cancer Chemother Pharmacol. 2019 Apr;83(4):639-647. doi: 10.1007/s00280-019-03769-7. Epub 2019 Jan 14.
512 Copine5 expression predicts prognosis following curative resection of esophageal squamous cell carcinoma.Oncol Rep. 2018 Dec;40(6):3772-3780. doi: 10.3892/or.2018.6742. Epub 2018 Sep 27.
513 Genomic alterations with impact on survival in esophageal squamous cell carcinoma identified by array comparative genomic hybridization.Genes Chromosomes Cancer. 2011 Jul;50(7):518-26. doi: 10.1002/gcc.20875. Epub 2011 Apr 11.
514 Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma.Oncogene. 2007 Sep 27;26(44):6456-68. doi: 10.1038/sj.onc.1210459. Epub 2007 Apr 16.
515 Cellular Retinoic Acid Binding Protein 2 Is Strikingly Downregulated in Human Esophageal Squamous Cell Carcinoma and Functions as a Tumor Suppressor.PLoS One. 2016 Feb 3;11(2):e0148381. doi: 10.1371/journal.pone.0148381. eCollection 2016.
516 CRCT1 regulated by microRNA-520g inhibits proliferation and induces apoptosis in esophageal squamous cell cancer.Tumour Biol. 2016 Jun;37(6):8271-9. doi: 10.1007/s13277-015-4730-2. Epub 2015 Dec 30.
517 Low expression of cyclic AMP response element modulator-1 can increase the migration and invasion of esophageal squamous cell carcinoma.Tumour Biol. 2013 Dec;34(6):3649-57. doi: 10.1007/s13277-013-0946-1. Epub 2013 Aug 9.
518 The LIM domain protein, CRIP2, promotes apoptosis in esophageal squamous cell carcinoma.Cancer Lett. 2012 Mar;316(1):39-45. doi: 10.1016/j.canlet.2011.10.020. Epub 2011 Oct 20.
519 Dysregulation of Rab37-Mediated Cross-talk between Cancer Cells and Endothelial Cells via Thrombospondin-1 Promotes Tumor Neovasculature and Metastasis.Clin Cancer Res. 2017 May 1;23(9):2335-2345. doi: 10.1158/1078-0432.CCR-16-1520. Epub 2016 Nov 15.
520 Sporamin suppresses growth of human esophageal squamous cell carcinoma cells by inhibition of NFB via an AKTindependent pathway.Mol Med Rep. 2017 Dec;16(6):9620-9626. doi: 10.3892/mmr.2017.7772. Epub 2017 Oct 12.
521 Ranking candidate genes of esophageal squamous cell carcinomas based on differentially expressed genes and the topological properties of the co-expression network.Eur J Med Res. 2014 Oct 29;19(1):52. doi: 10.1186/s40001-014-0052-x.
522 Research progress of cystatin SN in cancer.Onco Targets Ther. 2019 May 6;12:3411-3419. doi: 10.2147/OTT.S194332. eCollection 2019.
523 Clinicopathological significance of cystatin A expression in progression of esophageal squamous cell carcinoma.Medicine (Baltimore). 2018 Apr;97(15):e0357. doi: 10.1097/MD.0000000000010357.
524 Cancer-testis gene expression profiling in esophageal squamous cell carcinoma: identification of specific tumor marker and potential targets for immunotherapy.Cancer Biol Ther. 2011 Aug 1;12(3):191-7. doi: 10.4161/cbt.12.3.15949. Epub 2011 Aug 1.
525 LncRNA NEAT1 Regulates Cell Viability and Invasion in Esophageal Squamous Cell Carcinoma through the miR-129/CTBP2 Axis.Dis Markers. 2017;2017:5314649. doi: 10.1155/2017/5314649. Epub 2017 Sep 25.
526 Overexpression of Cullin4A correlates with a poor prognosis and tumor progression in esophageal squamous cell carcinoma.Int J Clin Oncol. 2020 Mar;25(3):446-455. doi: 10.1007/s10147-019-01547-2. Epub 2019 Sep 18.
527 MicroRNA-133b inhibits cell proliferation and promotes apoptosis by targeting cullin 4B in esophageal squamous cell carcinoma.Exp Ther Med. 2018 Apr;15(4):3743-3750. doi: 10.3892/etm.2018.5906. Epub 2018 Feb 28.
528 IL-17 induces antitumor immunity by promoting beneficial neutrophil recruitment and activation in esophageal squamous cell carcinoma.Oncoimmunology. 2017 Sep 21;7(1):e1373234. doi: 10.1080/2162402X.2017.1373234. eCollection 2017.
529 Aberrant methylation of DACT1 and DACT2 are associated with tumor progression and poor prognosis in esophageal squamous cell carcinoma.J Biomed Sci. 2017 Jan 11;24(1):6. doi: 10.1186/s12929-016-0308-6.
530 CpG island hypermethylation of E-cadherin (CDH1) and integrin alpha4 is associated with recurrence of early stage esophageal squamous cell carcinoma.Int J Cancer. 2008 Nov 1;123(9):2073-9. doi: 10.1002/ijc.23598.
531 Identification of specific and common diagnostic antibody markers for gastrointestinal cancers by SEREX screening using testis cDNA phage library.Oncotarget. 2018 Jan 1;9(26):18559-18569. doi: 10.18632/oncotarget.24963. eCollection 2018 Apr 6.
532 SnoN overexpression is predictive of poor survival in patients with esophageal squamous cell carcinoma.Ann Surg Oncol. 2008 Oct;15(10):2965-75. doi: 10.1245/s10434-008-9986-y. Epub 2008 Jul 9.
533 Genetic polymorphisms of microRNA machinery genes predict overall survival of esophageal squamous carcinoma.J Clin Lab Anal. 2018 Jan;32(1):e22170. doi: 10.1002/jcla.22170. Epub 2017 Dec 11.
534 Knockdown of DDX46 inhibits proliferation and induces apoptosis in esophageal squamous cell carcinoma cells.Oncol Rep. 2016 Jul;36(1):223-30. doi: 10.3892/or.2016.4803. Epub 2016 May 11.
535 Reduced expression of DENND2D through promoter hypermethylation is an adverse prognostic factor in squamous cell carcinoma of the esophagus.Oncol Rep. 2014 Feb;31(2):693-700. doi: 10.3892/or.2013.2901. Epub 2013 Dec 5.
536 Derlin-1 is a target to improve radiotherapy effect of esophageal squamous cell carcinoma.Oncotarget. 2017 Jul 7;8(33):55135-55146. doi: 10.18632/oncotarget.19069. eCollection 2017 Aug 15.
537 Inverse expression of dihydrodiol dehydrogenase and glutathione-S-transferase in patients with esophageal squamous cell carcinoma.Int J Cancer. 2004 Aug 20;111(2):246-51. doi: 10.1002/ijc.11650.
538 Molecular pathogenesis of esophageal squamous cell carcinoma: Identification of the antitumor effects of miR?45?p on gene regulation.Int J Oncol. 2019 Feb;54(2):673-688. doi: 10.3892/ijo.2018.4657. Epub 2018 Dec 6.
539 Downregulation of the novel tumor suppressor DIRAS1 predicts poor prognosis in esophageal squamous cell carcinoma.Cancer Res. 2013 Apr 1;73(7):2298-309. doi: 10.1158/0008-5472.CAN-12-2663. Epub 2013 Feb 22.
540 Long noncoding RNA DLX6AS1 is associated with malignant progression and promotes proliferation and invasion in esophageal squamous cell carcinoma.Mol Med Rep. 2019 Mar;19(3):1942-1950. doi: 10.3892/mmr.2018.9786. Epub 2018 Dec 21.
541 Intronic polymorphisms in genes LRFN2 (rs2494938) and DNAH11 (rs2285947) are prognostic indicators of esophageal squamous cell carcinoma.BMC Med Genet. 2019 May 3;20(1):72. doi: 10.1186/s12881-019-0796-9.
542 Candidate susceptibility variants for esophageal squamous cell carcinoma.Genes Chromosomes Cancer. 2017 Jun;56(6):453-459. doi: 10.1002/gcc.22448. Epub 2017 Apr 3.
543 Repression of DOK7 mediated by DNMT3A promotes the proliferation and invasion of KYSE410 and TE-12 ESCC cells.Biomed Pharmacother. 2017 Jun;90:93-99. doi: 10.1016/j.biopha.2017.02.111. Epub 2017 Mar 24.
544 Oncogenic but non-essential role of N-myc downstream regulated gene 1 in the progression of esophageal squamous cell carcinoma.Cancer Biol Ther. 2013 Feb;14(2):164-74. doi: 10.4161/cbt.22956. Epub 2012 Nov 28.
545 Relationship between altered expression levels of MIR21, MIR143, MIR145, and MIR205 and clinicopathologic features of esophageal squamous cell carcinoma.Dis Esophagus. 2011 Sep;24(7):523-30. doi: 10.1111/j.1442-2050.2011.01177.x. Epub 2011 Mar 31.
546 Tumor suppressor dual-specificity phosphatase 6 (DUSP6) impairs cell invasion and epithelial-mesenchymal transition (EMT)-associated phenotype.Int J Cancer. 2012 Jan 1;130(1):83-95. doi: 10.1002/ijc.25970. Epub 2011 Apr 20.
547 RAP1B, a DVL2 binding protein, activates Wnt/beta-catenin signaling in esophageal squamous cell carcinoma.Gene. 2017 May 5;611:15-20. doi: 10.1016/j.gene.2017.01.021. Epub 2017 Jan 21.
548 Role and mechanism of Dvl3 in the esophageal squamous cell carcinoma.Eur Rev Med Pharmacol Sci. 2018 Nov;22(22):7716-7725. doi: 10.26355/eurrev_201811_16393.
549 MicroRNA-544 inhibits esophageal squamous cell carcinoma cell proliferation and enhances sensitivity to cisplatin by repressing E2F transcription factor 5.Oncol Lett. 2019 Oct;18(4):4203-4209. doi: 10.3892/ol.2019.10749. Epub 2019 Aug 16.
550 E2F transcription factor 8 promotes cell proliferation via CCND1/p21 in esophageal squamous cell carcinoma.Onco Targets Ther. 2018 Nov 15;11:8165-8173. doi: 10.2147/OTT.S180938. eCollection 2018.
551 Endoplasmic reticulum-localized ECM1b suppresses tumor growth and regulates MYC and MTORC1 through modulating MTORC2 activation in esophageal squamous cell carcinoma.Cancer Lett. 2019 Oct 1;461:56-64. doi: 10.1016/j.canlet.2019.07.005. Epub 2019 Jul 15.
552 The effect of ephrin-A1 on resistance to Photofrin-mediated photodynamic therapy in esophageal squamous cell carcinoma cells.Lasers Med Sci. 2015 Dec;30(9):2353-61. doi: 10.1007/s10103-015-1812-8. Epub 2015 Oct 8.
553 Effects of EHD2 interference on migration of esophageal squamous cell carcinoma.Med Oncol. 2013 Mar;30(1):396. doi: 10.1007/s12032-012-0396-4. Epub 2013 Jan 25.
554 Increased expression of EHF contributes to thyroid tumorigenesis through transcriptionally regulating HER2 and HER3.Oncotarget. 2016 Sep 6;7(36):57978-57990. doi: 10.18632/oncotarget.11154.
555 miR-483-3p plays an oncogenic role in esophageal squamous cell carcinoma by targeting tumor suppressor EI24.Cell Biol Int. 2016 Apr;40(4):448-55. doi: 10.1002/cbin.10585. Epub 2016 Feb 4.
556 TEX9 and eIF3b functionally synergize to promote the progression of esophageal squamous cell carcinoma.BMC Cancer. 2019 Sep 3;19(1):875. doi: 10.1186/s12885-019-6071-9.
557 Up-regulation Of EIF3e Is Associated with The Progression of Esophageal Squamous Cell Carcinoma and Poor Prognosis in Patients.J Cancer. 2018 Mar 8;9(7):1135-1144. doi: 10.7150/jca.22546. eCollection 2018.
558 Overexpression of Ets-like protein 1 in human esophageal squamous cell carcinoma.World J Gastroenterol. 2006 Dec 28;12(48):7859-63. doi: 10.3748/wjg.v12.i48.7859.
559 EPB41L3 is a potential tumor suppressor gene and prognostic indicator in esophageal squamous cell carcinoma.Int J Oncol. 2018 May;52(5):1443-1454. doi: 10.3892/ijo.2018.4316. Epub 2018 Mar 14.
560 Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells.J Exp Clin Cancer Res. 2017 Aug 1;36(1):101. doi: 10.1186/s13046-017-0572-7.
561 Association of high-dose postoperative opioids with recurrence risk in esophageal squamous cell carcinoma: reinterpreting ERAS protocols for long-term oncologic surgery outcomes.Dis Esophagus. 2017 Oct 1;30(10):1-8. doi: 10.1093/dote/dox074.
562 Clinical Role of Excision Repair Cross-Complementing 1 Gene Expression in Resected Esophageal Squamous Cell Carcinoma: A Meta-Analysis.Dig Dis Sci. 2020 Aug;65(8):2264-2271. doi: 10.1007/s10620-019-05941-8. Epub 2019 Nov 11.
563 Genetic risk of subsequent esophageal cancer in lymphoma and breast cancer long-term survival patients: a pilot study.Pharmacogenomics J. 2016 Jun;16(3):266-71. doi: 10.1038/tpj.2015.41. Epub 2015 Jun 9.
564 Excision repair cross complementing 3 expression is involved in patient prognosis and tumor progression in esophageal cancer.Oncol Rep. 2004 Oct;12(4):827-31.
565 Risk Factors Associated with Precancerous Lesions of Esophageal Squamous Cell Carcinoma: a Screening Study in a High Risk Chinese Population.J Cancer. 2019 Jun 2;10(14):3284-3290. doi: 10.7150/jca.29979. eCollection 2019.
566 An actin-binding protein ESPN is an independent prognosticator and regulates cell growth for esophageal squamous cell carcinoma.Cancer Cell Int. 2018 Dec 29;18:219. doi: 10.1186/s12935-018-0713-x. eCollection 2018.
567 Contribution of EVX1 in Aggressiveness of Esophageal Squamous Cell Carcinoma.Pathol Oncol Res. 2016 Apr;22(2):341-7. doi: 10.1007/s12253-015-0005-x. Epub 2015 Nov 9.
568 Aberrant methylation of EYA4 promotes epithelial-mesenchymal transition in esophageal squamous cell carcinoma.Cancer Sci. 2018 Jun;109(6):1811-1824. doi: 10.1111/cas.13615. Epub 2018 May 26.
569 FAM3B promotes progression of oesophageal carcinoma via regulating the AKT-MDM2-p53 signalling axis and the epithelial-mesenchymal transition.J Cell Mol Med. 2019 Feb;23(2):1375-1385. doi: 10.1111/jcmm.14040. Epub 2018 Dec 18.
570 Prognostic significance of FAM3C in esophageal squamous cell carcinoma.Diagn Pathol. 2015 Oct 24;10:192. doi: 10.1186/s13000-015-0424-8.
571 MiR-455-3p acts as a prognostic marker and inhibits the proliferation and invasion of esophageal squamous cell carcinoma by targeting FAM83F.Eur Rev Med Pharmacol Sci. 2017 Jul;21(14):3200-3206.
572 Identification of miR-29c and its Target FBXO31 as a Key Regulatory Mechanism in Esophageal Cancer Chemoresistance: Functional Validation and Clinical Significance.Theranostics. 2019 Feb 28;9(6):1599-1613. doi: 10.7150/thno.30372. eCollection 2019.
573 Aberrant methylation and decreased expression of the TGF-/Smad target gene FBXO32 in esophageal squamous cell carcinoma.Cancer. 2014 Aug 15;120(16):2412-23. doi: 10.1002/cncr.28764. Epub 2014 May 2.
574 Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma.Nat Commun. 2019 Mar 21;10(1):1296. doi: 10.1038/s41467-019-09179-w.
575 Flap endonuclease-1 rs174538 G>A polymorphisms are associated with the risk of esophageal cancer in a Chinese population.Thorac Cancer. 2017 May;8(3):192-196. doi: 10.1111/1759-7714.12422. Epub 2017 Mar 20.
576 Identification and Validation of Fibroblast Growth Factor 12 Gene as a Novel Potential Biomarker in Esophageal Cancer Using Cancer Genomic Datasets.OMICS. 2017 Oct;21(10):616-631. doi: 10.1089/omi.2017.0116.
577 Inhibitory effects of Gleditsia sinensis fruit extract on telomerase activity and oncogenic expression in human esophageal squamous cell carcinoma.Int J Mol Med. 2007 Jun;19(6):953-60.
578 FGF5 methylation is a sensitivity marker of esophageal squamous cell carcinoma to definitive chemoradiotherapy.Sci Rep. 2019 Sep 16;9(1):13347. doi: 10.1038/s41598-019-50005-6.
579 FGFRL1 deficiency reduces motility and tumorigenic potential of cells derived from oesophageal squamous cell carcinomas.Oncol Lett. 2018 Jul;16(1):809-814. doi: 10.3892/ol.2018.8739. Epub 2018 May 18.
580 FLI-06 suppresses proliferation, induces apoptosis and cell cycle arrest by targeting LSD1 and Notch pathway in esophageal squamous cell carcinoma cells.Biomed Pharmacother. 2018 Nov;107:1370-1376. doi: 10.1016/j.biopha.2018.08.140. Epub 2018 Aug 31.
581 Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma.Oncotarget. 2017 Jan 24;8(4):6353-6363. doi: 10.18632/oncotarget.14087.
582 MicroRNA-127 is a tumor suppressor in human esophageal squamous cell carcinoma through the regulation of oncogene FMNL3.Eur J Pharmacol. 2016 Nov 15;791:603-610. doi: 10.1016/j.ejphar.2016.09.025. Epub 2016 Sep 17.
583 Tumor suppressor microRNA-34a inhibits cell migration and invasion by targeting MMP-2/MMP-9/FNDC3B in esophageal squamous cell carcinoma.Int J Oncol. 2017 Jul;51(1):378-388. doi: 10.3892/ijo.2017.4015. Epub 2017 May 19.
584 Overexpression of the Long Noncoding RNA FOXD2-AS1 Promotes Cisplatin Resistance in Esophageal Squamous Cell Carcinoma Through the miR-195/Akt/mTOR Axis.Oncol Res. 2020 Feb 7;28(1):65-73. doi: 10.3727/096504019X15656904013079. Epub 2019 Sep 26.
585 FOXF2 promoter methylation is associated with prognosis in esophageal squamous cell carcinoma.Tumour Biol. 2017 Feb;39(2):1010428317692230. doi: 10.1177/1010428317692230.
586 Epigenetically Upregulated MicroRNA-602 Is Involved in a Negative Feedback Loop with FOXK2 in Esophageal Squamous Cell Carcinoma.Mol Ther. 2019 Oct 2;27(10):1796-1809. doi: 10.1016/j.ymthe.2019.07.006. Epub 2019 Jul 19.
587 microRNA-messenger RNA regulatory network of esophageal squamous cell carcinoma and the identification of miR-1 as a biomarker of patient survival.J Cell Biochem. 2019 Aug;120(8):12259-12272. doi: 10.1002/jcb.28166. Epub 2019 Apr 24.
588 FSTL1 Promotes Metastasis and Chemoresistance in Esophageal Squamous Cell Carcinoma through NFB-BMP Signaling Cross-talk.Cancer Res. 2017 Nov 1;77(21):5886-5899. doi: 10.1158/0008-5472.CAN-17-1411. Epub 2017 Sep 7.
589 Far upstream element-binding protein 1 (FUBP1) is a potential c-Myc regulator in esophageal squamous cell carcinoma (ESCC) and its expression promotes ESCC progression.Tumour Biol. 2016 Mar;37(3):4115-26. doi: 10.1007/s13277-015-4263-8. Epub 2015 Oct 21.
590 Overexpression of FXYD-3 is involved in the tumorigenesis and development of esophageal squamous cell carcinoma.Dis Markers. 2013;35(3):195-202. doi: 10.1155/2013/740201. Epub 2013 Aug 27.
591 The prognostic role of FZD6 in esophageal squamous cell carcinoma patients.Clin Transl Oncol. 2020 Jul;22(7):1172-1179. doi: 10.1007/s12094-019-02243-3. Epub 2019 Nov 20.
592 Upregulation of a novel lncRNA LINC01980 promotes tumor growth of esophageal squamous cell carcinoma.Biochem Biophys Res Commun. 2019 May 21;513(1):73-80. doi: 10.1016/j.bbrc.2019.03.012. Epub 2019 Mar 29.
593 GALNT14 genotype as a response predictor for concurrent chemoradiotherapy in advanced esophageal squamous cell carcinoma.Oncotarget. 2017 Apr 25;8(17):29151-29160. doi: 10.18632/oncotarget.16253.
594 miR-214 inhibits invasion and migration via downregulating GALNT7 in esophageal squamous cell cancer.Tumour Biol. 2016 Nov;37(11):14605-14614. doi: 10.1007/s13277-016-5320-7. Epub 2016 Sep 12.
595 Genome wide copy number analyses of superficial esophageal squamous cell carcinoma with and without metastasis.Oncotarget. 2017 Jan 17;8(3):5069-5080. doi: 10.18632/oncotarget.13847.
596 Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54.Nat Genet. 2010 Sep;42(9):759-63. doi: 10.1038/ng.648. Epub 2010 Aug 22.
597 GCNT2 induces epithelial-mesenchymal transition and promotes migration and invasion in esophageal squamous cell carcinoma cells.Cell Biochem Funct. 2019 Jan;37(1):42-51. doi: 10.1002/cbf.3371. Epub 2018 Dec 21.
598 Expression of nucleostemin, epidermal growth factor and epidermal growth factor receptor in human esophageal squamous cell carcinoma tissues.J Cancer Res Clin Oncol. 2010 Apr;136(4):587-94. doi: 10.1007/s00432-009-0693-2. Epub 2009 Oct 13.
599 Identification of genes associated with histologic tumor grade of esophageal squamous cell carcinoma.FEBS Open Bio. 2017 Jul 28;7(9):1246-1257. doi: 10.1002/2211-5463.12228. eCollection 2017 Sep.
600 Evaluation of Salivary Exosomal Chimeric GOLM1-NAA35 RNA as a Potential Biomarker in Esophageal Carcinoma.Clin Cancer Res. 2019 May 15;25(10):3035-3045. doi: 10.1158/1078-0432.CCR-18-3169. Epub 2019 Feb 11.
601 GOLPH3 promotes cell proliferation and tumorigenicity in esophageal squamous cell carcinoma via mTOR and Wnt/catenin signal activation.Mol Med Rep. 2017 Nov;16(5):7138-7144. doi: 10.3892/mmr.2017.7495. Epub 2017 Sep 13.
602 Glypican-1 Promotes Tumorigenesis by Regulating the PTEN/Akt/-Catenin Signaling Pathway in Esophageal Squamous Cell Carcinoma.Dig Dis Sci. 2019 Jun;64(6):1493-1502. doi: 10.1007/s10620-019-5461-9. Epub 2019 Feb 7.
603 High levels of RAI3 expression is linked to shortened survival in esophageal cancer patients.Exp Mol Pathol. 2019 Apr;107:51-56. doi: 10.1016/j.yexmp.2019.01.013. Epub 2019 Jan 29.
604 Overexpression of activator of G-protein signaling 3 decreases the proliferation of esophageal squamous cell carcinoma.Pathol Res Pract. 2015 Jun;211(6):449-55. doi: 10.1016/j.prp.2014.12.016. Epub 2015 Feb 19.
605 Identity-by-descent approaches identify regions of importance for genetic susceptibility to hereditary esophageal squamous cell carcinoma.Oncol Rep. 2014 Aug;32(2):860-70. doi: 10.3892/or.2014.3222. Epub 2014 May 29.
606 Promoter methylation and clinical significance of GPX3 in esophageal squamous cell carcinoma.Pathol Res Pract. 2019 Nov;215(11):152676. doi: 10.1016/j.prp.2019.152676. Epub 2019 Sep 27.
607 An Integrative Analysis to Identify Driver Genes in Esophageal Squamous Cell Carcinoma.PLoS One. 2015 Oct 14;10(10):e0139808. doi: 10.1371/journal.pone.0139808. eCollection 2015.
608 Suppressor gene GRHL1 is associated with prognosis in patients with oesophageal squamous cell carcinoma.Oncol Lett. 2019 May;17(5):4313-4320. doi: 10.3892/ol.2019.10072. Epub 2019 Feb 25.
609 Over-expression of gastrin-releasing peptide in human esophageal squamous cell carcinomas.Carcinogenesis. 2004 Jun;25(6):865-71. doi: 10.1093/carcin/bgh097. Epub 2004 Feb 4.
610 Overexpression of TFIIB-related factor 2 is significantly correlated with tumor angiogenesis and poor survival in patients with esophageal squamous cell cancer.Med Oncol. 2013 Jun;30(2):553. doi: 10.1007/s12032-013-0553-4. Epub 2013 Apr 2.
611 Inhibition of oesophageal squamous cell carcinoma progression by in vivo targeting of hyaluronan synthesis.Mol Cancer. 2011 Mar 23;10:30. doi: 10.1186/1476-4598-10-30.
612 RNAi screening identifies HAT1 as a potential drug target in esophageal squamous cell carcinoma.Int J Clin Exp Pathol. 2014 Jun 15;7(7):3898-907. eCollection 2014.
613 The E3 ligase HECTD3 promotes esophageal squamous cell carcinoma (ESCC) growth and cell survival through targeting and inhibiting caspase-9 activation.Cancer Lett. 2017 Sep 28;404:44-52. doi: 10.1016/j.canlet.2017.07.004. Epub 2017 Jul 15.
614 Genetic variants at 4q21, 4q23 and 12q24 are associated with esophageal squamous cell carcinoma risk in a Chinese population.Hum Genet. 2013 Jun;132(6):649-56. doi: 10.1007/s00439-013-1276-5. Epub 2013 Feb 22.
615 Notch Signaling Target Genes are Directly Correlated to Esophageal Squamous Cell Carcinoma Tumorigenesis.Pathol Oncol Res. 2015 Apr;21(2):463-7. doi: 10.1007/s12253-014-9849-8. Epub 2014 Nov 1.
616 Epigenetic silencing of HIC1 promotes epithelial-mesenchymal transition and drives progression in esophageal squamous cell carcinoma.Oncotarget. 2015 Nov 10;6(35):38151-65. doi: 10.18632/oncotarget.5832.
617 Identification of a novel fusion gene (HLA-E and HLA-B) by RNA-seq analysis in esophageal squamous cell carcinoma.Asian Pac J Cancer Prev. 2014;15(5):2309-12. doi: 10.7314/apjcp.2014.15.5.2309.
618 Alteration of HLA-F and HLA I antigen expression in the tumor is associated with survival in patients with esophageal squamous cell carcinoma.Int J Cancer. 2013 Jan 1;132(1):82-9. doi: 10.1002/ijc.27621. Epub 2012 May 17.
619 Aberrant methylation is frequently observed in advanced esophageal squamous cell carcinoma.Anticancer Res. 2006 Sep-Oct;26(5A):3333-5.
620 Silencing HMGN5 suppresses cell growth and promotes chemosensitivity in esophageal squamous cell carcinoma. J Biochem Mol Toxicol. 2017 Dec;31(12). doi: 10.1002/jbt.21996. Epub 2017 Sep 15.
621 LBX2-AS1 is activated by ZEB1 and promotes the development of esophageal squamous cell carcinoma by interacting with HNRNPC toenhance the stability of ZEB1 and ZEB2 mRNAs.Biochem Biophys Res Commun. 2019 Apr 9;511(3):566-572. doi: 10.1016/j.bbrc.2019.02.079. Epub 2019 Feb 26.
622 Protein and gene expression characteristics of heterogeneous nuclear ribonucleoprotein H1 in esophageal squamous cell carcinoma.World J Gastroenterol. 2016 Aug 28;22(32):7322-31. doi: 10.3748/wjg.v22.i32.7322.
623 HOP/OB1/NECC1 promoter DNA is frequently hypermethylated and involved in tumorigenic ability in esophageal squamous cell carcinoma.Mol Cancer Res. 2008 Jan;6(1):31-41. doi: 10.1158/1541-7786.MCR-07-0213.
624 Genome-wide screening of DNA methylation associated with lymph node metastasis in esophageal squamous cell carcinoma.Oncotarget. 2017 Jun 6;8(23):37740-37750. doi: 10.18632/oncotarget.17147.
625 Targeting HOX/PBX dimer formation as a potential therapeutic option in esophageal squamous cell carcinoma.Cancer Sci. 2019 May;110(5):1735-1745. doi: 10.1111/cas.13993. Epub 2019 Apr 5.
626 HOXC13 promotes proliferation of esophageal squamous cell carcinoma via repressing transcription of CASP3.Cancer Sci. 2018 Feb;109(2):317-329. doi: 10.1111/cas.13453. Epub 2017 Dec 20.
627 Increased HOXC6 expression predicts chemotherapy sensitivity in patients with esophageal squamous cell carcinoma.Oncol Lett. 2017 Oct;14(4):4835-4840. doi: 10.3892/ol.2017.6772. Epub 2017 Aug 18.
628 Homeobox D10, a tumor suppressor, inhibits the proliferation and migration of esophageal squamous cell carcinoma.J Cell Biochem. 2019 Aug;120(8):13717-13725. doi: 10.1002/jcb.28644. Epub 2019 Apr 2.
629 Overexpression of HSPA2 is correlated with poor prognosis in esophageal squamous cell carcinoma.World J Surg Oncol. 2013 Jun 18;11:141. doi: 10.1186/1477-7819-11-141.
630 Expression of Heat Shock Protein-27 (Hsp27) and P38MAPK in Esophageal Squamous Cell Carcinoma.Med Sci Monit. 2017 Nov 3;23:5246-5253. doi: 10.12659/msm.904912.
631 The protein-protein interaction network and clinical significance of heat-shock proteins in esophageal squamous cell carcinoma.Amino Acids. 2018 Jun;50(6):685-697. doi: 10.1007/s00726-018-2569-8. Epub 2018 Apr 27.
632 Upregulation of IBSP Expression Predicts Poor Prognosis in Patients With Esophageal Squamous Cell Carcinoma.Front Oncol. 2019 Oct 25;9:1117. doi: 10.3389/fonc.2019.01117. eCollection 2019.
633 Transcriptome network analysis reveals potential candidate genes for esophageal squamous cell carcinoma.Asian Pac J Cancer Prev. 2012;13(3):767-73. doi: 10.7314/apjcp.2012.13.3.767.
634 Overexpression of IFITM3 predicts poor prognosis in stage IIA esophageal squamous cell carcinoma after Ivor Lewis esophagectomy.Thorac Cancer. 2017 Nov;8(6):592-599. doi: 10.1111/1759-7714.12488. Epub 2017 Aug 30.
635 Frequent microsatellite alterations on chromosome 3p in esophageal squamous cell carcinoma.Cancer Res. 1995 Feb 15;55(4):891-4.
636 Prognostic significance of preoperative IKBKE expression in esophageal squamous cell carcinoma.Onco Targets Ther. 2018 Mar 7;11:1305-1314. doi: 10.2147/OTT.S156818. eCollection 2018.
637 Interleukin 1B rs16944 G>A polymorphism was associated with a decreased risk of esophageal cancer in a Chinese population.Clin Biochem. 2013 Oct;46(15):1469-73. doi: 10.1016/j.clinbiochem.2013.05.050. Epub 2013 May 29.
638 NF45 promotes esophageal squamous carcinoma cell invasion by increasing Rac1 activity through 14-3-3 protein.Arch Biochem Biophys. 2019 Mar 15;663:101-108. doi: 10.1016/j.abb.2018.12.012. Epub 2018 Dec 11.
639 An NF90/long noncoding RNA-LET/miR-548k feedback amplification loop controls esophageal squamous cell carcinoma progression.J Cancer. 2019 Aug 28;10(21):5139-5152. doi: 10.7150/jca.30816. eCollection 2019.
640 Genetic alterations of candidate tumor suppressor ING1 in human esophageal squamous cell cancer.Cancer Res. 2001 Jun 1;61(11):4345-9.
641 ING5 inhibits cell proliferation and invasion in esophageal squamous cell carcinoma through regulation of the Akt/NF-B/MMP-9 signaling pathway.Biochem Biophys Res Commun. 2018 Feb 5;496(2):387-393. doi: 10.1016/j.bbrc.2018.01.045. Epub 2018 Jan 8.
642 Allelic loss on chromosome 13q14 and mutation in deleted in cancer 1 gene in esophageal squamous cell carcinoma.Oncogene. 2003 Jan 16;22(2):314-8. doi: 10.1038/sj.onc.1206098.
643 Overexpression of IQGAP1 promotes the angiogenesis of esophageal squamous cell carcinoma through the AKT and ERKmediated VEGFVEGFR2 signaling pathway.Oncol Rep. 2018 Sep;40(3):1795-1802. doi: 10.3892/or.2018.6558. Epub 2018 Jul 11.
644 RNA editing is induced by type I interferon in esophageal squamous cell carcinoma.Tumour Biol. 2017 Jul;39(7):1010428317708546. doi: 10.1177/1010428317708546.
645 Overexpression of OLC1 promotes tumorigenesis of human esophageal squamous cell carcinoma.PLoS One. 2014 Mar 7;9(3):e90958. doi: 10.1371/journal.pone.0090958. eCollection 2014.
646 Integrin 7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma.Nat Commun. 2016 Dec 7;7:13568. doi: 10.1038/ncomms13568.
647 MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth.Cancer Cell Int. 2018 Nov 22;18:193. doi: 10.1186/s12935-018-0684-y. eCollection 2018.
648 NS1-binding protein radiosensitizes esophageal squamous cell carcinoma by transcriptionally suppressing c-Myc.Cancer Commun (Lond). 2018 Jun 5;38(1):33. doi: 10.1186/s40880-018-0307-y.
649 Contribution of KCTD12 to esophageal squamous cell carcinoma.BMC Cancer. 2018 Aug 29;18(1):853. doi: 10.1186/s12885-018-4765-z.
650 The Prognostic Significance of Histone Demethylase UTX in Esophageal Squamous Cell Carcinoma.Int J Mol Sci. 2018 Jan 19;19(1):297. doi: 10.3390/ijms19010297.
651 Prognostic and clinicopathological significance of kinesin family member C1 in various cancers: A meta-analysis.Medicine (Baltimore). 2019 Oct;98(40):e17346. doi: 10.1097/MD.0000000000017346.
652 Cell Signaling Pathway in 12-O-Tetradecanoylphorbol-13-acetate-Induced LCN2 Gene Transcription in Esophageal Squamous Cell Carcinoma.Biomed Res Int. 2017;2017:9592501. doi: 10.1155/2017/9592501. Epub 2017 Oct 2.
653 Krppel-like factor 9 was down-regulated in esophageal squamous cell carcinoma and negatively regulated beta-catenin/TCF signaling.Mol Carcinog. 2016 Mar;55(3):280-91. doi: 10.1002/mc.22277. Epub 2015 Jan 16.
654 KLK11 suppresses cellular proliferation via inhibition of Wnt/-catenin signaling pathway in esophageal squamous cell carcinoma.Am J Cancer Res. 2019 Oct 1;9(10):2264-2277. eCollection 2019.
655 Correction to: Expression of kallikrein-related peptidase 13 is associated with poor prognosis in esophageal squamous cell carcinoma.Gen Thorac Cardiovasc Surg. 2018 Jun;66(6):376-377. doi: 10.1007/s11748-018-0923-0.
656 MLL3 promotes the senescence of esophageal squamous cell carcinoma.Onco Targets Ther. 2019 Mar 1;12:1575-1582. doi: 10.2147/OTT.S187540. eCollection 2019.
657 shRNAmediated knockdown of KNTC1 suppresses cell viability and induces apoptosis in esophageal squamous cell carcinoma.Int J Oncol. 2019 Mar;54(3):1053-1060. doi: 10.3892/ijo.2019.4672. Epub 2019 Jan 3.
658 SNHG8 is upregulated in esophageal squamous cell carcinoma and directly sponges microRNA-411 to increase oncogenicity by upregulating KPNA2.Onco Targets Ther. 2019 Aug 28;12:6991-7004. doi: 10.2147/OTT.S214881. eCollection 2019.
659 Krppel-like Factor 4 Promotes Esophageal Squamous Cell Carcinoma Differentiation by Up-regulating Keratin 13 Expression.J Biol Chem. 2015 May 22;290(21):13567-77. doi: 10.1074/jbc.M114.629717. Epub 2015 Apr 7.
660 Fascin and CK4 as biomarkers for esophageal squamous cell carcinoma.Anticancer Res. 2011 Mar;31(3):945-52.
661 Evaluation of serum HGF and CK18 levels in patients with esophageal cancer.Genet Mol Res. 2016 Aug 29;15(3). doi: 10.4238/gmr.15038583.
662 Circulatory miR-98-5p levels are deregulated during diabetes and it inhibits proliferation and promotes apoptosis by targeting PPP1R15B in keratinocytes.RNA Biol. 2020 Feb;17(2):188-201. doi: 10.1080/15476286.2019.1673117. Epub 2019 Oct 15.
663 MicroRNA-202 inhibits tumor progression by targeting LAMA1 in esophageal squamous cell carcinoma.Biochem Biophys Res Commun. 2016 May 13;473(4):821-827. doi: 10.1016/j.bbrc.2016.03.130. Epub 2016 Apr 1.
664 Elevated HBXIP expression is associated with aggressive phenotype and poor prognosis in esophageal squamous cell carcinoma.Am J Cancer Res. 2017 Nov 1;7(11):2190-2198. eCollection 2017.
665 Clinical Significance and Phenotype of MTA1 Expression in Esophageal Squamous Cell Carcinoma.Anticancer Res. 2017 Aug;37(8):4147-4155. doi: 10.21873/anticanres.11802.
666 The transcription factor LEF1 promotes tumorigenicity and activates the TGF- signaling pathway in esophageal squamous cell carcinoma.J Exp Clin Cancer Res. 2019 Jul 11;38(1):304. doi: 10.1186/s13046-019-1296-7.
667 Identification of LETM1 as a marker of cancer stem-like cells and predictor of poor prognosis in esophageal squamous cell carcinoma.Hum Pathol. 2018 Nov;81:148-156. doi: 10.1016/j.humpath.2018.07.001. Epub 2018 Jul 18.
668 Are Serum Mac 2-Binding Protein Levels Elevated in Esophageal Cancer? A Control Study of Esophageal Squamous Cell Carcinoma Patients.Dis Markers. 2018 Apr 17;2018:3610239. doi: 10.1155/2018/3610239. eCollection 2018.
669 Galectin-9 Induces Mitochondria-Mediated Apoptosis of Esophageal Cancer In Vitro and In Vivo in a Xenograft Mouse Model.Int J Mol Sci. 2019 May 29;20(11):2634. doi: 10.3390/ijms20112634.
670 Downregulation of LGI1 promotes tumor metastasis in esophageal squamous cell carcinoma.Carcinogenesis. 2014 May;35(5):1154-61. doi: 10.1093/carcin/bgu040. Epub 2014 Feb 7.
671 Identification of genetic variants in base excision repair pathway and their associations with risk of esophageal squamous cell carcinoma.Cancer Res. 2004 Jun 15;64(12):4378-84. doi: 10.1158/0008-5472.CAN-04-0372.
672 Hugl-1 induces apoptosis in esophageal carcinoma cells both in vitro and in vivo.World J Gastroenterol. 2013 Jul 14;19(26):4127-36. doi: 10.3748/wjg.v19.i26.4127.
673 Genomic analyses reveal FAM84B and the NOTCH pathway are associated with the progression of esophageal squamous cell carcinoma.Gigascience. 2016 Jan 11;5:1. doi: 10.1186/s13742-015-0107-0. eCollection 2016.
674 The Clinical Prognostic Value of LRG1 in Esophageal Squamous Cell Carcinoma.Curr Cancer Drug Targets. 2019;19(9):756-763. doi: 10.2174/1568009619666190204095942.
675 Genetic or epigenetic silencing of low density lipoprotein receptor-related protein 1B expression in oral squamous cell carcinoma.Cancer Sci. 2006 Oct;97(10):1070-4. doi: 10.1111/j.1349-7006.2006.00283.x.
676 LRRC8A Expression Influences Growth of Esophageal Squamous Cell Carcinoma.Am J Pathol. 2019 Oct;189(10):1973-1985. doi: 10.1016/j.ajpath.2019.06.006. Epub 2019 Jul 16.
677 Prognostic value of pretreatment serum alanine aminotransferase/aspartate aminotransferase (ALT/AST) ratio and gamma glutamyltransferase (GGT) in patients with esophageal squamous cell carcinoma.BMC Cancer. 2017 Aug 14;17(1):544. doi: 10.1186/s12885-017-3523-y.
678 The ECM protein LTBP-2 is a suppressor of esophageal squamous cell carcinoma tumor formation but higher tumor expression associates with poor patient outcome.Int J Cancer. 2011 Aug 1;129(3):565-73. doi: 10.1002/ijc.25698. Epub 2010 Nov 9.
679 MiR-214 promotes cell meastasis and inhibites apoptosis of esophageal squamous cell carcinoma via PI3K/AKT/mTOR signaling pathway.Biomed Pharmacother. 2018 Sep;105:350-361. doi: 10.1016/j.biopha.2018.05.149. Epub 2018 Jun 1.
680 MACC1 induces autophagy to regulate proliferation, apoptosis, migration and invasion of squamous cell carcinoma.Oncol Rep. 2017 Oct;38(4):2369-2377. doi: 10.3892/or.2017.5889. Epub 2017 Aug 8.
681 REV7 confers radioresistance of esophagus squamous cell carcinoma by recruiting PRDX2.Cancer Sci. 2019 Mar;110(3):962-972. doi: 10.1111/cas.13946. Epub 2019 Feb 8.
682 Inflammatory cytokines are associated with response and prognosis in patients with esophageal cancer.Oncotarget. 2017 Jul 18;8(29):47518-47532. doi: 10.18632/oncotarget.17671.
683 Identification of novel NRAGE involved in the radioresistance of esophageal cancer cells.Tumour Biol. 2016 Jul;37(7):8741-52. doi: 10.1007/s13277-015-4747-6. Epub 2016 Jan 7.
684 Increased expression of MARCH8, an E3 ubiquitin ligase, is associated with growth of esophageal tumor.Cancer Cell Int. 2017 Dec 4;17:116. doi: 10.1186/s12935-017-0490-y. eCollection 2017.
685 Dysphagia predict the response to second cycle neoadjuvant chemotherapy in first cycle no response esophageal carcinoma.J Thorac Dis. 2019 Oct;11(10):4135-4143. doi: 10.21037/jtd.2019.10.02.
686 High p53 and MAP1 light chain 3A co-expression predicts poor prognosis in patients with esophageal squamous cell carcinoma.Mol Med Rep. 2013 Jul;8(1):41-6. doi: 10.3892/mmr.2013.1451. Epub 2013 Apr 30.
687 Ablation of MCM10 using CRISPR/Cas9 restrains the growth and migration of esophageal squamous cell carcinoma cells through inhibition of Akt signaling.Onco Targets Ther. 2018 Jun 6;11:3323-3333. doi: 10.2147/OTT.S157025. eCollection 2018.
688 MSP58 knockdown inhibits the proliferation of esophageal squamous cell carcinoma in vitro and in vivo.Asian Pac J Cancer Prev. 2012;13(7):3233-8. doi: 10.7314/apjcp.2012.13.7.3233.
689 Monocarboxylate transporter1 is an independent prognostic factor in esophageal squamous cell carcinoma.Oncol Rep. 2019 Apr;41(4):2529-2539. doi: 10.3892/or.2019.6992. Epub 2019 Jan 31.
690 DNA methylation of genes linked to retinoid signaling in squamous cell carcinoma of the esophagus: DNA methylation of CRBP1 and TIG1 is associated with tumor stage.Cancer Sci. 2005 Sep;96(9):571-7. doi: 10.1111/j.1349-7006.2005.00082.x.
691 Downregulation of MED23 promoted the tumorigenecity of esophageal squamous cell carcinoma.Mol Carcinog. 2014 Oct;53(10):833-40. doi: 10.1002/mc.22041. Epub 2013 Apr 27.
692 Focally amplified lncRNA on chromosome 1 regulates apoptosis of esophageal cancer cells via DRP1 and mitochondrial dynamics.IUBMB Life. 2019 Feb;71(2):254-260. doi: 10.1002/iub.1971. Epub 2018 Nov 30.
693 MIB-1 index is unlikely to predict relapse-free survival in patients who underwent R0-esophagectomy for esophageal squamous cell carcinoma.Dis Esophagus. 2018 May 1;31(5). doi: 10.1093/dote/dox145.
694 Implication of Highly Cytotoxic Natural Killer Cells for Esophageal Squamous Cell Carcinoma Treatment.J Immunother. 2018 Jul/Aug;41(6):261-273. doi: 10.1097/CJI.0000000000000227.
695 Aquaporin 1 suppresses apoptosis and affects prognosis in esophageal squamous cell carcinoma.Oncotarget. 2018 Jul 6;9(52):29957-29974. doi: 10.18632/oncotarget.25722. eCollection 2018 Jul 6.
696 Polymorphisms in mTORC1 genes modulate risk of esophageal squamous cell carcinoma in eastern Chinese populations.J Thorac Oncol. 2013 Jun;8(6):788-95. doi: 10.1097/JTO.0b013e31828916c6.
697 Genetic variation in miR-100 rs1834306 is associated with decreased risk for esophageal squamous cell carcinoma in Kazakh patients in northwest China.Int J Clin Exp Pathol. 2015 Jun 1;8(6):7332-40. eCollection 2015.
698 Association of matrilysin-2 (MMP-26) expression with tumor progression and activation of MMP-9 in esophageal squamous cell carcinoma.Carcinogenesis. 2004 Dec;25(12):2353-60. doi: 10.1093/carcin/bgh270. Epub 2004 Aug 27.
699 Down-regulation of RIP3 potentiates cisplatin chemoresistance by triggering HSP90-ERK pathway mediated DNA repair in esophageal squamous cell carcinoma.Cancer Lett. 2018 Apr 1;418:97-108. doi: 10.1016/j.canlet.2018.01.022. Epub 2018 Jan 10.
700 p16, MGMT, RARbeta2, CLDN3, CRBP and MT1G gene methylation in esophageal squamous cell carcinoma and its precursor lesions.Oncol Rep. 2006 Jun;15(6):1591-7.
701 Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation.Mol Cancer. 2005 Dec 13;4:42. doi: 10.1186/1476-4598-4-42.
702 The role of mitochondrial folate enzyme MTHFD1L in esophageal squamous cell carcinoma.Scand J Gastroenterol. 2018 May;53(5):533-540. doi: 10.1080/00365521.2017.1407440. Epub 2017 Nov 24.
703 The impact of Metastasis Suppressor-1, MTSS1, on oesophageal squamous cell carcinoma and its clinical significance.J Transl Med. 2011 Jun 22;9:95. doi: 10.1186/1479-5876-9-95.
704 The expression and prognostic significance of Mucin 13 and Mucin 20 in esophageal squamous cell carcinoma.J Cancer Res Ther. 2015 Aug;11 Suppl 1:C74-9. doi: 10.4103/0973-1482.163846.
705 Accurate discrimination of Barrett's esophagus and esophageal adenocarcinoma using a quantitative three-tiered algorithm and multimarker real-time reverse transcription-PCR.Clin Cancer Res. 2005 Mar 15;11(6):2205-14. doi: 10.1158/1078-0432.CCR-04-1091.
706 Prognostic implications and oncogenic roles of MYBL2 protein expression in esophageal squamous-cell carcinoma.Onco Targets Ther. 2019 Mar 8;12:1917-1927. doi: 10.2147/OTT.S190145. eCollection 2019.
707 Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review).Oncol Rep. 2003 Sep-Oct;10(5):1615-23.
708 MYEOV, a gene at 11q13, is coamplified with CCND1, but epigenetically inactivated in a subset of esophageal squamous cell carcinomas.J Hum Genet. 2002;47(9):460-4. doi: 10.1007/s100380200065.
709 Expression and prognostic significance of MYL9 in esophageal squamous cell carcinoma.PLoS One. 2017 Apr 7;12(4):e0175280. doi: 10.1371/journal.pone.0175280. eCollection 2017.
710 Correlations of ALDH2 rs671 and C12orf30 rs4767364 polymorphisms with increased risk and prognosis of esophageal squamous cell carcinoma in the Kazak and Han populations in Xinjiang province.J Clin Lab Anal. 2018 Feb;32(2):e22248. doi: 10.1002/jcla.22248. Epub 2017 May 2.
711 Aberrant chimeric RNA GOLM1-MAK10 encoding a secreted fusion protein as a molecular signature for human esophageal squamous cell carcinoma.Oncotarget. 2013 Nov;4(11):2135-43. doi: 10.18632/oncotarget.1465.
712 The prognostic value of B7-H6 in esophageal squamous cell carcinoma.Sci Rep. 2019 Dec 2;9(1):18122. doi: 10.1038/s41598-019-54731-9.
713 Identification of hub genes and therapeutic drugs in esophageal squamous cell carcinoma based on integrated bioinformatics strategy.Cancer Cell Int. 2019 May 22;19:142. doi: 10.1186/s12935-019-0854-6. eCollection 2019.
714 Immediate and substantial evolution of T-cell repertoire in peripheral blood and tumor microenvironment of patients with esophageal squamous cell carcinoma treated with preoperative chemotherapy.Carcinogenesis. 2018 Dec 13;39(11):1389-1398. doi: 10.1093/carcin/bgy116.
715 Expression of NDRG2 in esophageal squamous cell carcinoma.Cancer Sci. 2010 May;101(5):1292-9. doi: 10.1111/j.1349-7006.2010.01529.x. Epub 2010 Feb 11.
716 Elevated Nectin-2 expression is involved in esophageal squamous cell carcinoma by promoting cell migration and invasion.Oncol Lett. 2018 Apr;15(4):4731-4736. doi: 10.3892/ol.2018.7953. Epub 2018 Feb 5.
717 Neurofilament heavy polypeptide regulates the Akt-beta-catenin pathway in human esophageal squamous cell carcinoma.PLoS One. 2010 Feb 3;5(2):e9003. doi: 10.1371/journal.pone.0009003.
718 A NEIL1 single nucleotide polymorphism (rs4462560) predicts the risk of radiation-induced toxicities in esophageal cancer patients treated with definitive radiotherapy.Cancer. 2013 Dec 1;119(23):4205-11. doi: 10.1002/cncr.28338. Epub 2013 Sep 10.
719 The noncoding function of NELFA mRNA promotes the development of oesophageal squamous cell carcinoma by regulating the Rad17-RFC2-5 complex.Mol Oncol. 2020 Mar;14(3):611-624. doi: 10.1002/1878-0261.12619. Epub 2020 Jan 28.
720 Identification of differentially expressed genes in esophageal squamous cell carcinoma (ESCC) by cDNA expression array: overexpression of Fra-1, Neogenin, Id-1, and CDC25B genes in ESCC.Clin Cancer Res. 2001 Aug;7(8):2213-21.
721 NFAT1 promotes cell motility through MMP-3 in esophageal squamous cell carcinoma.Biomed Pharmacother. 2017 Feb;86:541-546. doi: 10.1016/j.biopha.2016.12.050. Epub 2016 Dec 23.
722 Prognostic significance of NFIA and NFIB in esophageal squamous carcinoma and esophagogastric junction adenocarcinoma.Cancer Med. 2018 May;7(5):1756-1765. doi: 10.1002/cam4.1434. Epub 2018 Mar 25.
723 MiR-1290 promotes cancer progression by targeting nuclear factor I/X(NFIX) in esophageal squamous cell carcinoma (ESCC).Biomed Pharmacother. 2015 Dec;76:82-93. doi: 10.1016/j.biopha.2015.10.005. Epub 2015 Nov 10.
724 Association of single nucleotide polymorphisms in ERCC2 gene and their haplotypes with esophageal squamous cell carcinoma.Tumour Biol. 2014 May;35(5):4225-31. doi: 10.1007/s13277-013-1553-x. Epub 2014 Jan 4.
725 Inhibition of PC4 radiosensitizes non-small cell lung cancer by transcriptionally suppressing XLF.Cancer Med. 2018 Apr;7(4):1326-1337. doi: 10.1002/cam4.1332. Epub 2018 Mar 9.
726 Elevated levels of serum nidogen-2 in esophageal squamous cell carcinoma.Cancer Biomark. 2018 Feb 14;21(3):583-590. doi: 10.3233/CBM-170484.
727 Nkx2-8 downregulation promotes angiogenesis and activates NF-B in esophageal cancer.Cancer Res. 2013 Jun 15;73(12):3638-48. doi: 10.1158/0008-5472.CAN-12-4028. Epub 2013 Apr 19.
728 Downregulation of NONO induces apoptosis, suppressing growth and invasion in esophageal squamous cell carcinoma.Oncol Rep. 2018 Jun;39(6):2575-2583. doi: 10.3892/or.2018.6334. Epub 2018 Mar 27.
729 Positive transforming growth factor- activated kinase-1 expression has an unfavorable impact on survival in T3N1-3M0 esophageal squamous cell carcinomas.Ann Thorac Surg. 2013 Jan;95(1):285-90. doi: 10.1016/j.athoracsur.2012.09.050. Epub 2012 Dec 25.
730 NR2F1-induced NR2F1-AS1 promotes esophageal squamous cell carcinoma progression via activating Hedgehog signaling pathway.Biochem Biophys Res Commun. 2019 Nov 12;519(3):497-504. doi: 10.1016/j.bbrc.2019.09.015. Epub 2019 Sep 14.
731 NRD1, which encodes nardilysin protein, promotes esophageal cancer cell invasion through induction of MMP2 and MMP3 expression.Cancer Sci. 2014 Jan;105(1):134-40. doi: 10.1111/cas.12316. Epub 2013 Nov 29.
732 MicroRNA-548-3p and MicroRNA-576-5p enhance the migration and invasion of esophageal squamous cell carcinoma cells via NRIP1 down-regulation.Neoplasma. 2018 Nov 15;65(6):881-887. doi: 10.4149/neo_2018_171206N803. Epub 2018 Jun 17.
733 Discovery and Validation of a Serologic Autoantibody Panel for Early Diagnosis of Esophageal Squamous Cell Carcinoma.Cancer Epidemiol Biomarkers Prev. 2019 Sep;28(9):1454-1460. doi: 10.1158/1055-9965.EPI-18-1269. Epub 2019 Jun 25.
734 Prognostic impact of MutT homolog-1 expression on esophageal squamous cell carcinoma.Cancer Med. 2017 Jan;6(1):258-266. doi: 10.1002/cam4.979. Epub 2016 Dec 5.
735 Increased Numb protein expression predicts poor clinical outcomes in esophageal squamous cell carcinoma patients.Cancer Biol Ther. 2018 Jan 2;19(1):34-41. doi: 10.1080/15384047.2016.1276131. Epub 2017 Dec 18.
736 Nucleolar spindle-associated protein 1 promotes tumorigenesis and predicts poor prognosis in human esophageal squamous cell carcinoma.J Cell Biochem. 2019 Jul;120(7):11726-11737. doi: 10.1002/jcb.28452. Epub 2019 Feb 21.
737 OTUB1 promotes esophageal squamous cell carcinoma metastasis through modulating Snail stability.Oncogene. 2018 Jun;37(25):3356-3368. doi: 10.1038/s41388-018-0224-1. Epub 2018 Mar 21.
738 Suppressor PAQR3 associated with the clinical significance and prognosis in esophageal squamous cell carcinoma.Oncol Lett. 2018 Apr;15(4):5703-5711. doi: 10.3892/ol.2018.8004. Epub 2018 Feb 8.
739 Singlecell intratumoral stemness analysis reveals the involvement of cell cycle and DNA damage repair in two different types of esophageal cancer.Oncol Rep. 2019 Jun;41(6):3201-3208. doi: 10.3892/or.2019.7117. Epub 2019 Apr 15.
740 Aberrant DNA methylation of PAX1, SOX1 and ZNF582 genes as potential biomarkers for esophageal squamous cell carcinoma.Biomed Pharmacother. 2019 Dec;120:109488. doi: 10.1016/j.biopha.2019.109488. Epub 2019 Oct 16.
741 Prognostic value of PAX9 in patients with esophageal squamous cell carcinoma and its prediction value to radiation sensitivity.Mol Med Rep. 2017 Jul;16(1):806-816. doi: 10.3892/mmr.2017.6626. Epub 2017 May 25.
742 Poly (C)-binding protein 2 (PCBP2) promotes the progression of esophageal squamous cell carcinoma (ESCC) through regulating cellular proliferation and apoptosis.Pathol Res Pract. 2016 Aug;212(8):717-25. doi: 10.1016/j.prp.2016.05.008. Epub 2016 May 27.
743 Frequent silencing of protocadherin 17, a candidate tumour suppressor for esophageal squamous cell carcinoma.Carcinogenesis. 2010 Jun;31(6):1027-36. doi: 10.1093/carcin/bgq053. Epub 2010 Mar 3.
744 Cancers Due to Smoking and High Alcohol Consumption.Dtsch Arztebl Int. 2018 Sep 3;115(35-36):571-577. doi: 10.3238/arztebl.2018.0571.
745 Piccolo mediates EGFR signaling and acts as a prognostic biomarker in esophageal squamous cell carcinoma.Oncogene. 2017 Jul 6;36(27):3890-3902. doi: 10.1038/onc.2017.15. Epub 2017 Mar 6.
746 Serum anti-myomegalin antibodies in patients with esophageal squamous cell carcinoma.Int J Oncol. 2007 Jan;30(1):97-103.
747 PDHA1 Gene Knockout In Human Esophageal Squamous Cancer Cells Resulted In Greater Warburg Effect And Aggressive Features In Vitro And In Vivo.Onco Targets Ther. 2019 Nov 18;12:9899-9913. doi: 10.2147/OTT.S226851. eCollection 2019.
748 Systematic profiling identifies PDLIM2 as a novel prognostic predictor for oesophageal squamous cell carcinoma (ESCC).J Cell Mol Med. 2019 Aug;23(8):5751-5761. doi: 10.1111/jcmm.14491. Epub 2019 Jun 20.
749 Overexpression of LASP1 is associated with proliferation, migration and invasion in esophageal squamous cell carcinoma.Oncol Rep. 2013 Mar;29(3):1115-23. doi: 10.3892/or.2012.2199. Epub 2012 Dec 19.
750 The expression of podoplanin protein is a diagnostic marker to distinguish the early infiltration of esophageal squamous cell carcinoma.Oncotarget. 2017 Mar 21;8(12):19013-19020. doi: 10.18632/oncotarget.14596.
751 Enhanced Expression of Fibroblast Growth Factor Receptor 3 IIIc Promotes Human Esophageal Carcinoma Cell Proliferation.J Histochem Cytochem. 2016 Jan;64(1):7-17. doi: 10.1369/0022155415616161. Epub 2015 Oct 20.
752 Metformin induces human esophageal carcinoma cell pyroptosis by targeting the miR-497/PELP1 axis.Cancer Lett. 2019 May 28;450:22-31. doi: 10.1016/j.canlet.2019.02.014. Epub 2019 Feb 13.
753 miRNA-Related Polymorphisms in miR-423 (rs6505162) and PEX6 (rs1129186) and Risk of Esophageal Squamous Cell Carcinoma in an Iranian Cohort.Genet Test Mol Biomarkers. 2017 Jun;21(6):382-390. doi: 10.1089/gtmb.2016.0346. Epub 2017 Apr 21.
754 Tissue-based quantitative proteomics to screen and identify the potential biomarkers for early recurrence/metastasis of esophageal squamous cell carcinoma.Cancer Med. 2018 Jun;7(6):2504-2517. doi: 10.1002/cam4.1463. Epub 2018 Apr 23.
755 Overexpression of Jumonji AT-rich interactive domain 1B and PHD finger protein 2 is involved in the progression of esophageal squamous cell carcinoma.Acta Histochem. 2013 Jan;115(1):56-62. doi: 10.1016/j.acthis.2012.04.001. Epub 2012 Apr 23.
756 Low PHLDA3 expression in oesophageal squamous cell carcinomas is associated with poor prognosis.Anticancer Res. 2015 Feb;35(2):949-54.
757 Histone Demethylase LSD1 Inhibitors Prevent Cell Growth by Regulating Gene Expression in Esophageal Squamous Cell Carcinoma Cells.Ann Surg Oncol. 2016 Jan;23(1):312-20. doi: 10.1245/s10434-015-4488-1. Epub 2015 Mar 20.
758 Expression and role of oncogenic miRNA-224 in esophageal squamous cell carcinoma.BMC Cancer. 2015 Aug 6;15:575. doi: 10.1186/s12885-015-1581-6.
759 MiR-141-3p is upregulated in esophageal squamous cell carcinoma and targets pleckstrin homology domain leucine-rich repeat protein phosphatase-2, a negative regulator of the PI3K/AKT pathway.Biochem Biophys Res Commun. 2018 Jun 22;501(2):507-513. doi: 10.1016/j.bbrc.2018.05.025. Epub 2018 May 16.
760 Phosphatidylinositol 3-kinase-C2 inhibits cisplatin-mediated apoptosis via the Akt pathway in oesophageal squamous cell carcinoma.J Int Med Res. 2011;39(4):1319-32. doi: 10.1177/147323001103900419.
761 MicroRNA-126 is down-regulated in human esophageal squamous cell carcinoma and inhibits the proliferation and migration in EC109 cell via PI3K/AKT signaling pathway.Int J Clin Exp Pathol. 2015 May 1;8(5):4745-54. eCollection 2015.
762 Esophageal squamous cell carcinoma transcriptome reveals the effect of FOXM1 on patient outcome through novel PIK3R3 mediated activation of PI3K signaling pathway.Oncotarget. 2018 Mar 30;9(24):16634-16647. doi: 10.18632/oncotarget.24621. eCollection 2018 Mar 30.
763 High Expression of the Mitophagy-Related Protein Pink1 is Associated with a Poor Response to Chemotherapy and a Poor Prognosis for Patients Treated with Neoadjuvant Chemotherapy for Esophageal Squamous Cell Carcinoma.Ann Surg Oncol. 2017 Dec;24(13):4025-4032. doi: 10.1245/s10434-017-6096-8. Epub 2017 Oct 11.
764 DNA hypermethyation and silencing of PITX1 correlated with advanced stage and poor postoperative prognosis of esophageal squamous cell carcinoma.Oncotarget. 2017 Sep 28;8(48):84434-84448. doi: 10.18632/oncotarget.21375. eCollection 2017 Oct 13.
765 Downregulation of MicroRNA-644a Promotes Esophageal Squamous Cell Carcinoma Aggressiveness and Stem Cell-like Phenotype via Dysregulation of PITX2.Clin Cancer Res. 2017 Jan 1;23(1):298-310. doi: 10.1158/1078-0432.CCR-16-0414. Epub 2016 Jul 12.
766 Association of single nucleotide polymorphisms in the prostaglandin-endoperoxide synthase 2 (PTGS2) and phospholipase A?group IIA (PLA2G2A) genes with susceptibility to esophageal squamous cell carcinoma.Asian Pac J Cancer Prev. 2014;15(4):1797-802. doi: 10.7314/apjcp.2014.15.4.1797.
767 Characterization of a novel tumor-suppressor gene PLC delta 1 at 3p22 in esophageal squamous cell carcinoma.Cancer Res. 2007 Nov 15;67(22):10720-6. doi: 10.1158/0008-5472.CAN-07-2411.
768 Replication study of PLCE1 and C20orf54 polymorphism and risk of esophageal cancer in a Chinese population.Mol Biol Rep. 2012 Sep;39(9):9105-11. doi: 10.1007/s11033-012-1782-x. Epub 2012 Jun 29.
769 The down-regulation of TAPP2 inhibits the migration of esophageal squamous cell carcinoma and predicts favorable outcome.Pathol Res Pract. 2017 Dec;213(12):1556-1562. doi: 10.1016/j.prp.2017.09.010. Epub 2017 Sep 12.
770 MicroRNA-134 prevents the progression of esophageal squamous cell carcinoma via the PLXNA1-mediated MAPK signalling pathway.EBioMedicine. 2019 Aug;46:66-78. doi: 10.1016/j.ebiom.2019.07.050. Epub 2019 Aug 2.
771 Phosphorylation of ETS-1 is a critical event in DNA polymerase iota-induced invasion and metastasis of esophageal squamous cell carcinoma.Cancer Sci. 2017 Dec;108(12):2503-2510. doi: 10.1111/cas.13399. Epub 2017 Oct 8.
772 Long noncoding RNAs POLR2E rs3787016 C/T and HULC rs7763881 A/C polymorphisms are associated with decreased risk of esophageal cancer.Tumour Biol. 2015 Aug;36(8):6401-8. doi: 10.1007/s13277-015-3328-z. Epub 2015 Mar 31.
773 Down-regulation of POTEG predicts poor prognosis in esophageal squamous cell carcinoma patients.Mol Carcinog. 2018 Jul;57(7):886-895. doi: 10.1002/mc.22809. Epub 2018 Apr 6.
774 Upregulation of the long noncoding RNA TUG1 promotes proliferation and migration of esophageal squamous cell carcinoma.Tumour Biol. 2015 Mar;36(3):1643-51. doi: 10.1007/s13277-014-2763-6. Epub 2014 Oct 31.
775 Interaction between alcohol consumption and CYP 2C19 gene polymorphism in relation to oesophageal squamous cell carcinoma.PLoS One. 2012;7(9):e43412. doi: 10.1371/journal.pone.0043412. Epub 2012 Sep 11.
776 Aberrant DNA hypermethylation reduces the expression of the desmosome-related molecule periplakin in esophageal squamous cell carcinoma.Cancer Med. 2015 Mar;4(3):415-25. doi: 10.1002/cam4.369. Epub 2015 Jan 12.
777 PRAF2 overexpression predicts poor prognosis and promotes tumorigenesis in esophageal squamous cell carcinoma.BMC Cancer. 2019 Jun 14;19(1):585. doi: 10.1186/s12885-019-5818-7.
778 Clinicopathological significance of pRb2/p130 expression in squamous cell carcinoma of the esophagus.J Cancer Res Clin Oncol. 2002 Dec;128(12):691-6. doi: 10.1007/s00432-002-0395-5. Epub 2002 Nov 26.
779 Effect of the downregulation of SMYD3 expression by RNAi on RIZ1 expression and proliferation of esophageal squamous cell carcinoma.Oncol Rep. 2014 Sep;32(3):1064-70. doi: 10.3892/or.2014.3307. Epub 2014 Jul 3.
780 Peroxiredoxin 1 is a tumor-associated antigen in esophageal squamous cell carcinoma.Oncol Rep. 2013 Nov;30(5):2297-303. doi: 10.3892/or.2013.2714. Epub 2013 Sep 4.
781 Overexpression of Peroxiredoxin 6 (PRDX6) Promotes the Aggressive Phenotypes of Esophageal Squamous Cell Carcinoma.J Cancer. 2018 Oct 10;9(21):3939-3949. doi: 10.7150/jca.26041. eCollection 2018.
782 PRIMA-1 induces p53-mediated apoptosis by upregulating Noxa in esophageal squamous cell carcinoma with TP53 missense mutation.Cancer Sci. 2018 Feb;109(2):412-421. doi: 10.1111/cas.13454. Epub 2017 Dec 28.
783 Overexpression of PRR11 promotes tumorigenic capability and is associated with progression in esophageal squamous cell carcinoma.Onco Targets Ther. 2019 Apr 9;12:2677-2693. doi: 10.2147/OTT.S180255. eCollection 2019.
784 Epigenetic silencing of the PRSS3 putative tumor suppressor gene in non-small cell lung cancer.Mol Carcinog. 2005 Oct;44(2):146-50. doi: 10.1002/mc.20125.
785 Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.Cancer Lett. 2018 Apr 1;418:125-134. doi: 10.1016/j.canlet.2018.01.025. Epub 2018 Jan 10.
786 PSMD7 downregulation induces apoptosis and suppresses tumorigenesis of esophageal squamous cell carcinoma via the mTOR/p70S6K pathway.FEBS Open Bio. 2018 Mar 7;8(4):533-543. doi: 10.1002/2211-5463.12394. eCollection 2018 Apr.
787 Overexpressed PTOV1 associates with tumorigenesis and progression of esophageal squamous cell carcinoma.Tumour Biol. 2017 Jun;39(6):1010428317705013. doi: 10.1177/1010428317705013.
788 Tyrosine-protein phosphatase nonreceptor type 12 is a novel prognostic biomarker for esophageal squamous cell carcinoma.Ann Thorac Surg. 2012 May;93(5):1674-80. doi: 10.1016/j.athoracsur.2011.12.056. Epub 2012 Mar 17.
789 PTPN9 promotes cell proliferation and invasion in Eca109 cells and is negatively regulated by microRNA-126.Oncol Lett. 2017 Aug;14(2):1419-1426. doi: 10.3892/ol.2017.6315. Epub 2017 Jun 6.
790 Aberrant methylation of the PTPRO gene in peripheral blood as a potential biomarker in esophageal squamous cell carcinoma patients.Cancer Lett. 2012 Feb 28;315(2):138-44. doi: 10.1016/j.canlet.2011.08.032. Epub 2011 Sep 12.
791 The Functional Variant in the 3'UTR of PTPRT with the Risk of Esophageal Squamous Cell Carcinoma in a Chinese Population.Cell Physiol Biochem. 2015;36(1):306-14. doi: 10.1159/000374073. Epub 2015 May 5.
792 Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus.Tumour Biol. 2017 May;39(5):1010428317708267. doi: 10.1177/1010428317708267.
793 The Pseudogene PTTG3P Promotes Cell Migration and Invasion in Esophageal Squamous Cell Carcinoma.Open Med (Wars). 2019 Jun 30;14:516-522. doi: 10.1515/med-2019-0057. eCollection 2019.
794 Increased expression of paxillin is found in human oesophageal squamous cell carcinoma: a tissue microarray study.J Int Med Res. 2008 Mar-Apr;36(2):273-8. doi: 10.1177/147323000803600209.
795 Association of PYGO2 and EGFR in esophageal squamous cell carcinoma.Med Oncol. 2013 Jun;30(2):516. doi: 10.1007/s12032-013-0516-9. Epub 2013 Mar 3.
796 MiR-143-3p functions as a tumor suppressor by regulating cell proliferation, invasion and epithelial-mesenchymal transition by targeting QKI-5 in esophageal squamous cell carcinoma.Mol Cancer. 2016 Jun 29;15(1):51. doi: 10.1186/s12943-016-0533-3.
797 Long Non-Coding RNA LINC00152 Regulates Cell Proliferation, Migration And Invasion In Esophageal Squamous Cell Carcinoma Via miR-107/Rab10 Axis.Onco Targets Ther. 2019 Oct 17;12:8553-8567. doi: 10.2147/OTT.S221515. eCollection 2019.
798 RAB23, regulated by miR-92b, promotes the progression of esophageal squamous cell carcinoma.Gene. 2016 Dec 20;595(1):31-38. doi: 10.1016/j.gene.2016.09.028. Epub 2016 Sep 19.
799 Rab25 is a tumor suppressor gene with antiangiogenic and anti-invasive activities in esophageal squamous cell carcinoma.Cancer Res. 2012 Nov 15;72(22):6024-35. doi: 10.1158/0008-5472.CAN-12-1269. Epub 2012 Sep 18.
800 Inhibitory effect of microRNA-455-5p on biological functions of esophageal squamous cell carcinoma Eca109 cells via Rab31.Exp Ther Med. 2018 Dec;16(6):4959-4966. doi: 10.3892/etm.2018.6820. Epub 2018 Oct 2.
801 Silencing of Rab3D suppresses the proliferation and invasion of esophageal squamous cell carcinoma cells.Biomed Pharmacother. 2017 Jul;91:402-407. doi: 10.1016/j.biopha.2017.04.010. Epub 2017 May 2.
802 Transcriptional gene expression profile of human esophageal squamous cell carcinoma.Genomics. 2003 May;81(5):481-8. doi: 10.1016/s0888-7543(03)00023-5.
803 RAD18 promotes the migration and invasion of esophageal squamous cell cancer via the JNK-MMPs pathway.Cancer Lett. 2018 Mar 28;417:65-74. doi: 10.1016/j.canlet.2017.12.034. Epub 2018 Jan 3.
804 Rap1A promotes esophageal squamous cell carcinoma metastasis through the AKT signaling pathway.Oncol Rep. 2019 Nov;42(5):1815-1824. doi: 10.3892/or.2019.7309. Epub 2019 Sep 12.
805 RasGRP3, a Ras guanyl releasing protein 3 that contributes to malignant proliferation and aggressiveness in human esophageal squamous cell carcinoma.Clin Exp Pharmacol Physiol. 2018 Jul;45(7):720-728. doi: 10.1111/1440-1681.12926. Epub 2018 Apr 10.
806 Epigenetic silencing of RASSF10 promotes tumor growth in esophageal squamous cell carcinoma.Discov Med. 2014 Apr;17(94):169-78.
807 Aberrant hypermethylation of RASSF2 in tumors and peripheral blood DNA as a biomarker for malignant progression and poor prognosis of esophageal squamous cell carcinoma.Clin Exp Metastasis. 2016 Jan;33(1):73-85. doi: 10.1007/s10585-015-9759-5.
808 RASSF5A, a candidate tumor suppressor, is epigenetically inactivated in esophageal squamous cell carcinoma.Clin Exp Metastasis. 2015 Jan;32(1):83-98. doi: 10.1007/s10585-015-9693-6. Epub 2015 Jan 13.
809 RASSF6-TRIM16 axis promotes cell proliferation, migration and invasion in esophageal squamous cell carcinoma.J Genet Genomics. 2019 Oct 20;46(10):477-488. doi: 10.1016/j.jgg.2019.10.004. Epub 2019 Nov 14.
810 RASSF8 downregulation promotes lymphangiogenesis and metastasis in esophageal squamous cell carcinoma.Oncotarget. 2015 Oct 27;6(33):34510-24. doi: 10.18632/oncotarget.5923.
811 RBBP7 is a prognostic biomarker in patients with esophageal squamous cell carcinoma.Oncol Lett. 2018 Dec;16(6):7204-7211. doi: 10.3892/ol.2018.9543. Epub 2018 Oct 3.
812 Reduced RBM3 expression is associated with aggressive tumor features in esophageal cancer but not significantly linked to patient outcome.BMC Cancer. 2018 Nov 12;18(1):1106. doi: 10.1186/s12885-018-5032-z.
813 miR-145 Regulates the sensitivity of esophageal squamous cell carcinoma cells to 5-FU via targeting REV3L.Pathol Res Pract. 2019 Jul;215(7):152427. doi: 10.1016/j.prp.2019.04.019. Epub 2019 Apr 28.
814 Clinical and prognostic significance of RhoA and RhoC gene expression in esophageal squamous cell carcinoma.Ann Surg Oncol. 2007 Dec;14(12):3593-601. doi: 10.1245/s10434-007-9562-x. Epub 2007 Sep 25.
815 KLF4 activates NFB signaling and esophageal epithelial inflammation via the Rho-related GTP-binding protein RHOF.PLoS One. 2019 Apr 18;14(4):e0215746. doi: 10.1371/journal.pone.0215746. eCollection 2019.
816 RIT1 suppresses esophageal squamous cell carcinoma growth and metastasis and predicts good prognosis.Cell Death Dis. 2018 Oct 22;9(11):1085. doi: 10.1038/s41419-018-0979-x.
817 Expression of Rac-1 related to tumor depth, lymph node metastasis and patient prognosis in esophageal squamous cell carcinoma.Med Oncol. 2013 Dec;30(4):689. doi: 10.1007/s12032-013-0689-2. Epub 2013 Sep 12.
818 The Rho GTPase RhoE exerts tumor-suppressing effects in human esophageal squamous cell carcinoma via negatively regulating epidermal growth factor receptor.J Cancer Res Ther. 2016 Oct;12(Supplement):60-63. doi: 10.4103/0973-1482.191633.
819 RNF113A promotes the proliferation, migration and invasion, and is associated with a poor prognosis of esophageal squamous cell carcinoma.Int J Oncol. 2018 Mar;52(3):861-871. doi: 10.3892/ijo.2018.4253. Epub 2018 Jan 24.
820 RNF128 Promotes Invasion and Metastasis Via the EGFR/MAPK/MMP-2 Pathway in Esophageal Squamous Cell Carcinoma.Cancers (Basel). 2019 Jun 18;11(6):840. doi: 10.3390/cancers11060840.
821 Association between RNF2+P-AKT expression in pretreatment biopsy specimens, and poor survival following radiotherapy in patients with esophageal squamous cell carcinoma.Oncol Lett. 2019 Oct;18(4):3734-3742. doi: 10.3892/ol.2019.10727. Epub 2019 Aug 7.
822 Corilagin Inhibits Esophageal Squamous Cell Carcinoma by Inducing DNA Damage and Down-Regulation of RNF8.Anticancer Agents Med Chem. 2019;19(8):1021-1028. doi: 10.2174/1871520619666190307120811.
823 RPN2 expression predicts response to docetaxel in oesophageal squamous cell carcinoma.Br J Cancer. 2012 Oct 9;107(8):1233-8. doi: 10.1038/bjc.2012.396. Epub 2012 Sep 6.
824 Prognostic significance and function of phosphorylated ribosomal protein S6 in esophageal squamous cell carcinoma.Mod Pathol. 2013 Mar;26(3):327-35. doi: 10.1038/modpathol.2012.161. Epub 2012 Sep 21.
825 Aberrant methylation of the Ras-related associated with diabetes gene in human primary esophageal cancer.Anticancer Res. 2013 Nov;33(11):5199-203.
826 Effects of PLCE1 gene silencing by RNA interference on cell cycling and apoptosis in esophageal carcinoma cells.Asian Pac J Cancer Prev. 2014;15(13):5437-42. doi: 10.7314/apjcp.2014.15.13.5437.
827 siRNA-mediated downregulation of TC21 sensitizes esophageal cancer cells to cisplatin.World J Gastroenterol. 2012 Aug 21;18(31):4127-35. doi: 10.3748/wjg.v18.i31.4127.
828 A novel gene, RSRC2, inhibits cell proliferation and affects survival in esophageal cancer patients.Int J Oncol. 2007 Feb;30(2):421-8.
829 Expression and clinical significance of C14orf166 in esophageal squamous cell carcinoma.Mol Med Rep. 2017 Feb;15(2):605-612. doi: 10.3892/mmr.2016.6056. Epub 2016 Dec 16.
830 Differential expression of S100 gene family in human esophageal squamous cell carcinoma.J Cancer Res Clin Oncol. 2004 Aug;130(8):480-6. doi: 10.1007/s00432-004-0555-x. Epub 2004 Jun 4.
831 S100A14 rs11548103 G>A polymorphism is associated with a decreased risk of esophageal cancer in a Chinese population.Oncotarget. 2017 Sep 14;8(49):86917-86923. doi: 10.18632/oncotarget.20868. eCollection 2017 Oct 17.
832 Downregulation of long non-coding RNA GAS5 promotes cell proliferation, migration and invasion in esophageal squamous cell carcinoma.Oncol Lett. 2018 Aug;16(2):1801-1808. doi: 10.3892/ol.2018.8797. Epub 2018 May 24.
833 mRNA and methylation profiling of radioresistant esophageal cancer cells: the involvement of Sall2 in acquired aggressive phenotypes.J Cancer. 2017 Feb 25;8(4):646-656. doi: 10.7150/jca.15652. eCollection 2017.
834 Correlation between SALL4 stemness marker and bone morphogenetic protein signaling genes in esophageal squamous cell carcinoma.J Biochem Mol Toxicol. 2019 Mar;33(3):e22262. doi: 10.1002/jbt.22262. Epub 2018 Nov 15.
835 MiR-130b promotes the progression of oesophageal squamous cell carcinoma by targeting SASH1.J Cell Mol Med. 2019 Jan;23(1):93-103. doi: 10.1111/jcmm.13887. Epub 2018 Nov 15.
836 Prognostic value of SATB2 expression in patients with esophageal squamous cell carcinoma.Int J Clin Exp Pathol. 2015 Jan 1;8(1):423-31. eCollection 2015.
837 Upregulated long non-coding RNA SBF2-AS1 promotes proliferation in esophageal squamous cell carcinoma.Oncol Lett. 2018 Apr;15(4):5071-5080. doi: 10.3892/ol.2018.7968. Epub 2018 Feb 6.
838 Human SBK1 is dysregulated in multiple cancers and promotes survival of ovary cancer SK-OV-3 cells.Mol Biol Rep. 2011 Jun;38(5):3551-9. doi: 10.1007/s11033-010-0465-8. Epub 2010 Nov 20.
839 Overexpression of Suprabasin is Associated with Proliferation and Tumorigenicity of Esophageal Squamous Cell Carcinoma.Sci Rep. 2016 Feb 22;6:21549. doi: 10.1038/srep21549.
840 MicroRNA-1290 promotes esophageal squamous cell carcinoma cell proliferation and metastasis.World J Gastroenterol. 2015 Mar 21;21(11):3245-55. doi: 10.3748/wjg.v21.i11.3245.
841 Analysis of Sciellin (SCEL) as a candidate gene in esophageal squamous cell carcinoma.Anticancer Res. 2004 May-Jun;24(3a):1417-9.
842 SEL1L and squamous cell carcinoma of the esophagus.Clin Cancer Res. 2004 Sep 1;10(17):5857-61. doi: 10.1158/1078-0432.CCR-04-0075.
843 Promoter hypermethylation-mediated downregulation of tumor suppressor gene SEMA3B and lncRNA SEMA3B-AS1 correlates with progression and prognosis of esophageal squamous cell carcinoma.Clin Exp Metastasis. 2019 Jun;36(3):225-241. doi: 10.1007/s10585-019-09964-3. Epub 2019 Mar 27.
844 Cellular distribution and clinical value of urokinase-type plasminogen activator, its receptor, and plasminogen activator inhibitor-2 in esophageal squamous cell carcinoma.Am J Pathol. 2000 Feb;156(2):567-75. doi: 10.1016/S0002-9440(10)64761-X.
845 SERPINE2 promotes esophageal squamous cell carcinoma metastasis by activating BMP4.Cancer Lett. 2020 Jan 28;469:390-398. doi: 10.1016/j.canlet.2019.11.011. Epub 2019 Nov 12.
846 Characterization of a novel mechanism of genomic instability involving the SEI1/SET/NM23H1 pathway in esophageal cancers.Cancer Res. 2010 Jul 15;70(14):5695-705. doi: 10.1158/0008-5472.CAN-10-0392. Epub 2010 Jun 22.
847 Directional Migration in Esophageal Squamous Cell Carcinoma (ESCC) is Epigenetically Regulated by SET Nuclear Oncogene, a Member of the Inhibitor of Histone Acetyltransferase Complex.Neoplasia. 2017 Nov;19(11):868-884. doi: 10.1016/j.neo.2017.08.003. Epub 2017 Sep 19.
848 The Silencing of SFRP2 Expression in ESCC Is Due to Methylation of the Gene Promoter.Technol Cancer Res Treat. 2019 Jan 1;18:1533033819877977. doi: 10.1177/1533033819877977.
849 High expression of SGTA in esophageal squamous cell carcinoma correlates with proliferation and poor prognosis.J Cell Biochem. 2014 Jan;115(1):141-50. doi: 10.1002/jcb.24641.
850 MiR-375 suppresses invasion and metastasis by direct targeting of SHOX2 in esophageal squamous cell carcinoma.Acta Biochim Biophys Sin (Shanghai). 2017 Feb 6;49(2):159-169. doi: 10.1093/abbs/gmw131.
851 Downregulation of SIRT4 Expression Is Associated with Poor Prognosis in Esophageal Squamous Cell Carcinoma.Oncology. 2016;90(6):347-55. doi: 10.1159/000445323. Epub 2016 Apr 16.
852 SIX1 overexpression predicts poor prognosis and induces radioresistance through AKT signaling in esophageal squamous cell carcinoma.Onco Targets Ther. 2017 Feb 21;10:1071-1079. doi: 10.2147/OTT.S125330. eCollection 2017.
853 SKA1 overexpression is associated with theprognosis of esophageal squamous cell carcinoma and regulates cell proliferation and migration.Int J Mol Med. 2019 Nov;44(5):1971-1978. doi: 10.3892/ijmm.2019.4343. Epub 2019 Sep 17.
854 Prediagnostic circulating inflammation biomarkers and esophageal squamous cell carcinoma: A case-cohort study in Japan.Int J Cancer. 2020 Aug 1;147(3):686-691. doi: 10.1002/ijc.32763. Epub 2019 Dec 3.
855 SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines.Sci Rep. 2019 Aug 12;9(1):11661. doi: 10.1038/s41598-019-48152-x.
856 Inhibition of SOX15 Sensitizes Esophageal Squamous Carcinoma Cells to Paclitaxel.Curr Mol Med. 2019;19(5):349-356. doi: 10.2174/1566524019666190405121139.
857 The effect of high Sox3 expression on lymphangiogenesis and lymph node metastasis in esophageal squamous cell carcinoma.Am J Transl Res. 2017 Jun 15;9(6):2684-2693. eCollection 2017.
858 Propofol Suppresses Esophageal Squamous Cell Carcinoma Cell Migration and Invasion by Down-Regulation of Sex-Determining Region Y-box 4 (SOX4).Med Sci Monit. 2017 Jan 24;23:419-427. doi: 10.12659/msm.899732.
859 LINC00473/miR-374a-5p regulates esophageal squamous cell carcinoma via targeting SPIN1 to weaken the effect of radiotherapy.J Cell Biochem. 2019 Sep;120(9):14562-14572. doi: 10.1002/jcb.28717. Epub 2019 Apr 24.
860 MicroRNA-1322 regulates ECRG2 allele specifically and acts as a potential biomarker in patients with esophageal squamous cell carcinoma.Mol Carcinog. 2013 Aug;52(8):581-90. doi: 10.1002/mc.21880. Epub 2012 Feb 7.
861 Decreased expression of SPINT1-AS1 and SPINT1 mRNA might be independent unfavorable prognostic indicators in esophageal squamous cell carcinoma.Onco Targets Ther. 2019 Jun 20;12:4755-4763. doi: 10.2147/OTT.S206448. eCollection 2019.
862 Epigenetic inactivation of SPINT2 is associated with tumor suppressive function in esophageal squamous cell carcinoma.Exp Cell Res. 2014 Mar 10;322(1):149-58. doi: 10.1016/j.yexcr.2013.11.009. Epub 2013 Nov 21.
863 Discovery of Ca2+-relevant and differentiation-associated genes downregulated in esophageal squamous cell carcinoma using cDNA microarray.Oncogene. 2004 Feb 12;23(6):1291-9. doi: 10.1038/sj.onc.1207218.
864 Quantitative evaluation of SPRR3 expression in esophageal squamous cell carcinoma by qPCR and its potential use as a biomarker.Exp Mol Pathol. 2011 Oct;91(2):584-9. doi: 10.1016/j.yexmp.2011.06.006. Epub 2011 Jul 12.
865 SPSB3 targets SNAIL for degradation in GSK-3 phosphorylation-dependent manner and regulates metastasis.Oncogene. 2018 Feb 8;37(6):768-776. doi: 10.1038/onc.2017.370. Epub 2017 Oct 23.
866 SRPX2 knockdown inhibits cell proliferation and metastasis and promotes chemosensitivity in esophageal squamous cell carcinoma.Biomed Pharmacother. 2019 Jan;109:671-678. doi: 10.1016/j.biopha.2018.10.042. Epub 2018 Nov 5.
867 Downregulation of ST6GALNAC1 is associated with esophageal squamous cell carcinoma development.Int J Oncol. 2017 Feb;50(2):441-447. doi: 10.3892/ijo.2016.3817. Epub 2016 Dec 22.
868 Serum Autoantibodies against STIP1 as a Potential Biomarker in the Diagnosis of Esophageal Squamous Cell Carcinoma.Dis Markers. 2017;2017:5384091. doi: 10.1155/2017/5384091. Epub 2017 Aug 9.
869 Essential role of STX6 in esophageal squamous cell carcinoma growth and migration.Biochem Biophys Res Commun. 2016 Mar 25;472(1):60-7. doi: 10.1016/j.bbrc.2016.02.061. Epub 2016 Feb 22.
870 TAB3 promotes human esophageal squamous cell carcinoma proliferation and invasion via the NFB pathway.Oncol Rep. 2018 Nov;40(5):2876-2885. doi: 10.3892/or.2018.6686. Epub 2018 Sep 6.
871 Polymorphisms in the 5' upstream regulatory region of p21(WAF1/CIP1) and susceptibility to oesophageal squamous cell carcinoma.Sci Rep. 2016 Mar 2;6:22564. doi: 10.1038/srep22564.
872 Expression of Transcription Factor 21 (TCF21) and Upregulation Its Level Inhibits Invasion and Metastasis in Esophageal Squamous Cell Carcinoma.Med Sci Monit. 2018 Jun 17;24:4128-4136. doi: 10.12659/MSM.909138.
873 MiR-216a-5p targets TCTN1 to inhibit cell proliferation and induce apoptosis in esophageal squamous cell carcinoma.Cell Mol Biol Lett. 2019 Jun 28;24:46. doi: 10.1186/s11658-019-0166-9. eCollection 2019.
874 Loss of 5-Hydroxymethylcytosine Is an Independent Unfavorable Prognostic Factor for Esophageal Squamous Cell Carcinoma.PLoS One. 2016 Apr 6;11(4):e0153100. doi: 10.1371/journal.pone.0153100. eCollection 2016.
875 Tex10 promotes stemness and EMT phenotypes in esophageal squamous cell carcinoma via the Wnt/catenin pathway.Oncol Rep. 2019 Dec;42(6):2600-2610. doi: 10.3892/or.2019.7376. Epub 2019 Oct 16.
876 Expression and prognostic significance of MAGE-A11 and transcription factors (SP1,TFCP2 and ZEB1) in ESCC tissues.Pathol Res Pract. 2019 Jul;215(7):152446. doi: 10.1016/j.prp.2019.152446. Epub 2019 May 8.
877 HIC-5 in cancer-associated fibroblasts contributes to esophageal squamous cell carcinoma progression.Cell Death Dis. 2019 Nov 18;10(12):873. doi: 10.1038/s41419-019-2114-z.
878 TGFBI Expression in Cancer Stromal Cells is Associated with Poor Prognosis and Hematogenous Recurrence in Esophageal Squamous Cell Carcinoma.Ann Surg Oncol. 2016 Jan;23(1):282-9. doi: 10.1245/s10434-014-4259-4. Epub 2014 Dec 2.
879 Monochromosome transfer and microarray analysis identify a critical tumor-suppressive region mapping to chromosome 13q14 and THSD1 in esophageal carcinoma.Mol Cancer Res. 2008 Apr;6(4):592-603. doi: 10.1158/1541-7786.MCR-07-0154.
880 Expression, prognosis and functional role of Thsd7a in esophageal squamous cell carcinoma of Kazakh patients, Xinjiang.Oncotarget. 2017 Apr 8;8(36):60539-60557. doi: 10.18632/oncotarget.16966. eCollection 2017 Sep 1.
881 THUMP domain containing 2 protein possibly induces resistance to cisplatin and 5-fluorouracil in in vitro human esophageal squamous cell carcinoma cells as revealed by transposon activation mutagenesis.J Gene Med. 2019 Dec;21(12):e3135. doi: 10.1002/jgm.3135. Epub 2019 Dec 18.
882 CD90 positive cells exhibit aggressive radioresistance in esophageal squamous cell carcinoma.J Thorac Dis. 2017 Mar;9(3):610-620. doi: 10.21037/jtd.2017.03.28.
883 Integrin 1 is a critical effector in promoting metastasis and chemo-resistance of esophageal squamous cell carcinoma.Am J Cancer Res. 2017 Mar 1;7(3):531-542. eCollection 2017.
884 MiR-21 down-regulation suppresses cell growth, invasion and induces cell apoptosis by targeting FASL, TIMP3, and RECK genes in esophageal carcinoma.Dig Dis Sci. 2013 Jul;58(7):1863-70. doi: 10.1007/s10620-013-2612-2. Epub 2013 Mar 17.
885 TM4SF1 promotes the self-renewal of esophageal cancer stem-like cells and is regulated by miR-141.Oncotarget. 2017 Mar 21;8(12):19274-19284. doi: 10.18632/oncotarget.13866.
886 Epigenetic silencing of TMEM176A promotes esophageal squamous cell cancer development.Oncotarget. 2017 Jul 25;8(41):70035-70048. doi: 10.18632/oncotarget.19550. eCollection 2017 Sep 19.
887 Modification of risk, but not survival of esophageal cancer patients by esophageal cancer-related gene 1 Arg290Gln polymorphism: a case-control study and meta-analysis.J Gastroenterol Hepatol. 2013 Nov;28(11):1717-24. doi: 10.1111/jgh.12335.
888 LncRNA-TUSC7/miR-224 affected chemotherapy resistance of esophageal squamous cell carcinoma by competitively regulating DESC1.J Exp Clin Cancer Res. 2018 Mar 12;37(1):56. doi: 10.1186/s13046-018-0724-4.
889 Relationship between transmembrane serine protease expression and prognosis of esophageal squamous cell carcinoma.J Biol Regul Homeost Agents. 2017 Oct-Dec;31(4):1067-1072.
890 Downregulation of TNFAIP2 suppresses proliferation and metastasis in esophageal squamous cell carcinoma through activation of the Wnt/-catenin signaling pathway.Oncol Rep. 2017 May;37(5):2920-2928. doi: 10.3892/or.2017.5557. Epub 2017 Apr 5.
891 Decreased Srcasm expression in esophageal squamous cell carcinoma in a Chinese population.Anticancer Res. 2010 Sep;30(9):3535-9.
892 Expression and significance of ASPP2 in squamous carcinoma of esophagus.Kaohsiung J Med Sci. 2018 Jun;34(6):321-329. doi: 10.1016/j.kjms.2017.12.011. Epub 2018 Jan 19.
893 A cancer-array approach elucidates the immune escape mechanism and defects in the DNA repair system in esophageal squamous cell carcinoma.Arch Iran Med. 2013 Aug;16(8):463-70.
894 Considering the downregulation of Tpm1.6 and Tpm1.7 in squamous cell carcinoma of esophagus as a potent biomarker.Per Med. 2018 Sep;15(5):361-370. doi: 10.2217/pme-2018-0015. Epub 2018 Sep 27.
895 TPM4 promotes cell migration by modulating F-actin formation in lung cancer.Onco Targets Ther. 2019 May 31;12:4055-4063. doi: 10.2147/OTT.S198542. eCollection 2019.
896 Expression and Association of Tumor Necrosis Factor Receptor Associated Factor 4 (TRAF4) in Esophageal Squamous Cell Carcinoma.Med Sci Monit. 2019 Apr 1;25:2368-2376. doi: 10.12659/MSM.915474.
897 Suppression of tumor necrosis factor receptor-associated protein 1 expression induces inhibition of cell proliferation and tumor growth in human esophageal cancer cells.FEBS J. 2014 Jun;281(12):2805-19. doi: 10.1111/febs.12822. Epub 2014 May 21.
898 Overexpression of TRIM44 is related to invasive potential and malignant outcomes in esophageal squamous cell carcinoma.Tumour Biol. 2017 Jun;39(6):1010428317700409. doi: 10.1177/1010428317700409.
899 TRIP13 upregulation is correlated with poor prognosis and tumor progression in esophageal squamous cell carcinoma.Pathol Res Pract. 2019 Jun;215(6):152415. doi: 10.1016/j.prp.2019.04.007. Epub 2019 Apr 17.
900 Effects and interactions of MiR-577 and TSGA10 in regulating esophageal squamous cell carcinoma.Int J Clin Exp Pathol. 2013 Nov 15;6(12):2651-67. eCollection 2013.
901 Genome-scale CRISPR activation screening identifies a role of ELAVL2-CDKN1A axis in paclitaxel resistance in esophageal squamous cell carcinoma.Am J Cancer Res. 2019 Jun 1;9(6):1183-1200. eCollection 2019.
902 Circ-TTC17 Promotes Proliferation and Migration of Esophageal Squamous Cell Carcinoma.Dig Dis Sci. 2019 Mar;64(3):751-758. doi: 10.1007/s10620-018-5382-z. Epub 2018 Dec 5.
903 Overexpression of AKIP1 promotes angiogenesis and lymphangiogenesis in human esophageal squamous cell carcinoma.Oncogene. 2015 Jan 15;34(3):384-93. doi: 10.1038/onc.2013.559. Epub 2014 Jan 13.
904 The expression and role of Aquaporin 5 in esophageal squamous cell carcinoma.J Gastroenterol. 2014 Apr;49(4):655-66. doi: 10.1007/s00535-013-0827-9. Epub 2013 May 9.
905 Analysis of the methylation status of genes up-regulated by the demethylating agent, 5-aza-2'-deoxycytidine, in esophageal squamous cell carcinoma.Oncol Rep. 2008 Aug;20(2):405-12.
906 Targeting WISP1 to sensitize esophageal squamous cell carcinoma to irradiation.Oncotarget. 2015 Mar 20;6(8):6218-34. doi: 10.18632/oncotarget.3358.
907 Pathway analysis of differentially expressed genes in human esophageal squamous cell carcinoma.Eur Rev Med Pharmacol Sci. 2015;19(9):1652-61.
908 Prognostic relevance and therapeutic implications of centromere protein F expression in patients with esophageal squamous cell carcinoma.Dis Esophagus. 2013 Aug;26(6):636-43. doi: 10.1111/dote.12002. Epub 2012 Nov 16.
909 Oncogenic properties of a novel gene JK-1 located in chromosome 5p and its overexpression in human esophageal squamous cell carcinoma.Int J Mol Med. 2007 Jun;19(6):915-23.
910 DCC promoter hypermethylation in esophageal squamous cell carcinoma.Int J Cancer. 2008 Jun 1;122(11):2498-502. doi: 10.1002/ijc.23434.
911 Molecular cloning of a candidate tumor suppressor gene, DLC1, from chromosome 3p21.3.Cancer Res. 1999 Apr 15;59(8):1966-72.
912 Expression of ECRG4 is associated with lower proliferative potential of esophageal cancer cells.Pathol Int. 2013 Aug;63(8):391-7. doi: 10.1111/pin.12079.
913 Epithelial membrane protein 3 is frequently shown as promoter methylation and functions as a tumor suppressor gene in non-small cell lung cancer.Exp Mol Pathol. 2013 Dec;95(3):313-8. doi: 10.1016/j.yexmp.2013.07.001. Epub 2013 Aug 3.
914 Genetic variants of DNA repair genes predict the survival of patients with esophageal squamous cell cancer receiving platinum-based adjuvant chemotherapy.J Transl Med. 2016 May 31;14(1):154. doi: 10.1186/s12967-016-0903-z.
915 Biomarkers of apoptosis and survival in esophageal squamous cell carcinoma.BMC Cancer. 2009 Sep 3;9:310. doi: 10.1186/1471-2407-9-310.
916 Genetic landscape of esophageal squamous cell carcinoma.Nat Genet. 2014 Oct;46(10):1097-102. doi: 10.1038/ng.3076. Epub 2014 Aug 24.
917 Guanylate-binding protein 1 (GBP1) promotes lymph node metastasis in human esophageal squamous cell carcinoma.Discov Med. 2015 Dec;20(112):369-78.
918 Interactions between Glutathione-S-Transferase M1, T1 and P1 polymorphisms and smoking, and increased susceptibility to esophageal squamous cell carcinoma.Cancer Epidemiol. 2010 Jun;34(3):285-90. doi: 10.1016/j.canep.2010.03.009. Epub 2010 Apr 20.
919 Usefulness of microRNA?75 as a prognostic and therapeutic tool in esophageal squamous cell carcinoma.Int J Oncol. 2015 Mar;46(3):1059-66. doi: 10.3892/ijo.2014.2789. Epub 2014 Dec 9.
920 Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production.Oncotarget. 2014 May 30;5(10):2962-73. doi: 10.18632/oncotarget.1561.
921 The expression of LC-3 is related to tumor suppression through angiogenesis in esophageal cancer.Med Oncol. 2013 Dec;30(4):701. doi: 10.1007/s12032-013-0701-x. Epub 2013 Oct 13.
922 Methyl-CpG binding domain 4 tagging polymorphisms and esophageal cancer risk in a Chinese population.Eur J Cancer Prev. 2015 Mar;24(2):100-5. doi: 10.1097/CEJ.0000000000000081.
923 Possible prediction of the response of esophageal squamous cell carcinoma to neoadjuvant chemotherapy based on gene expression profiling.Oncotarget. 2016 Jan 26;7(4):4531-41. doi: 10.18632/oncotarget.6554.
924 Over expression of p21-activated kinase 7 associates with lymph node metastasis in esophageal squamous cell cancers.Cancer Biomark. 2016;16(2):203-9. doi: 10.3233/CBM-150557.
925 Co-inhibition of BMI1 and Mel18 enhances chemosensitivity of esophageal squamous cell carcinoma in vitro and in vivo.Oncol Lett. 2019 Jun;17(6):5012-5022. doi: 10.3892/ol.2019.10160. Epub 2019 Mar 19.
926 LMP gene promoter hypermethylation is a mechanism for its down regulation in Kazak's esophageal squamous cell carcinomas.Mol Biol Rep. 2013 Mar;40(3):2069-75. doi: 10.1007/s11033-012-2138-2. Epub 2013 Jan 3.
927 Elevated DNA polymerase iota (Poli) is involved in the acquisition of aggressive phenotypes of human esophageal squamous cell cancer.Int J Clin Exp Pathol. 2015 Apr 1;8(4):3591-601. eCollection 2015.
928 DRD2/DARPP-32 expression correlates with lymph node metastasis and tumor progression in patients with esophageal squamous cell carcinoma.World J Surg. 2006 Sep;30(9):1672-9; discussion 1680-1. doi: 10.1007/s00268-006-0035-3.
929 Nuclear PROX1 is Associated with Hypoxia-Inducible Factor 1 Expression and Cancer Progression in Esophageal Squamous Cell Carcinoma.Ann Surg Oncol. 2015 Dec;22 Suppl 3:S1566-73. doi: 10.1245/s10434-015-4831-6. Epub 2015 Aug 27.
930 Inhibitory Role of Pentraxin-3 in Esophageal Squamous Cell Carcinoma.Chin Med J (Engl). 2016 Sep 20;129(18):2233-40. doi: 10.4103/0366-6999.189921.
931 RBMS3 is a tumor suppressor gene that acts as a favorable prognostic marker in lung squamous cell carcinoma.Med Oncol. 2015 Feb;32(2):459. doi: 10.1007/s12032-014-0459-9. Epub 2015 Jan 15.
932 miR-675-5p enhances tumorigenesis and metastasis of esophageal squamous cell carcinoma by targeting REPS2.Oncotarget. 2016 May 24;7(21):30730-47. doi: 10.18632/oncotarget.8950.
933 Chromosome 1 open reading frame 10 (C1orf10) gene is frequently down-regulated and inhibits cell proliferation in oral squamous cell carcinoma.Int J Biochem Cell Biol. 2005 Aug;37(8):1641-55. doi: 10.1016/j.biocel.2005.02.005. Epub 2005 Mar 5.
934 Expression and clinical significance of S100A2 and p63 in esophageal carcinoma.World J Gastroenterol. 2009 Sep 7;15(33):4183-8. doi: 10.3748/wjg.15.4183.
935 The role of Sox6 and Netrin-1 in ovarian cancer cell growth, invasiveness, and angiogenesis.Tumour Biol. 2017 May;39(5):1010428317705508. doi: 10.1177/1010428317705508.
936 Methylation of CLDN6, FBN2, RBP1, RBP4, TFPI2, and TMEFF2 in esophageal squamous cell carcinoma.Oncol Rep. 2009 Apr;21(4):1067-73. doi: 10.3892/or_00000325.