Details of the Drug

General Information of Drug (ID: DMWAO33)

Drug Name

SAR446159

Indication

Disease Entry	ICD 11	Status	REF
Parkinson disease	8A00.0	Phase 1	[1]
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Drug Type

Antibody

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Insulin-like growth factor I receptor (IGF1R)	TTHRID2	IGF1R_HUMAN	Not Available	[1]
Synuclein alpha (SNCA)	TT08OSU	SYUA_HUMAN	Not Available	[1]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Parkinson disease

ICD Disease Classification

8A00.0

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Synuclein alpha (SNCA)	DTT	SNCA	1.04E-01	-0.26	-0.33

Molecular Expression Atlas (MEA)

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References

1	Clinical pipeline report, company report or official report of Sanofi