Details of the Drug

General Information of Drug (ID: DMWG2K6)

Drug Name
AMG 199
Indication
Disease Entry ICD 11 Status REF
Esophagogastric junction neoplasm 2B71 Phase 1 [1]
Gastric adenocarcinoma 2B72 Phase 1 [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
DEP3Z8
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Mucin-17 (MUC17) TTVO0JU MUC17_HUMAN Inhibitor [2]
T-cell surface glycoprotein CD3 (CD3) TTUN7MC NOUNIPROTAC Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04117958) Study of AMG 199 in Subjects With MUC17-Positive Gastric and Gastroesophageal Junction Cancer. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Amgen.