Details of Disease | DrugMAP

General Information of Disease (ID: DISR35Z3)

Disease Name	Esophagogastric junction neoplasm
Disease Class	2B71: Oesophagogastric junction cancer
Disease Hierarchy	DIS01GPL: Grass pollen hypersensitivity DISR35Z3: Esophagogastric junction neoplasm
ICD Code	ICD-11 ICD-11: 2B71

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 3 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Zolbetuximab	DM5ST9Z	Phase 3	Antibody	[1]
AMG 199	DMWG2K6	Phase 1	Antibody	[2]
AMG 910	DMCG7XL	Phase 1	Antibody	[3]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1	ClinicalTrials.gov (NCT03504397) A Phase 3 Efficacy, Safety and Tolerability Study of Zolbetuximab (Experimental Drug) Plus mFOLFOX6 Chemotherapy Compared to Placebo Plus mFOLFOX6 as Treatment for Gastric and Gastroesophageal Junction (GEJ) Cancer (Spotlight). U.S. National Institutes of Health.
2	ClinicalTrials.gov (NCT04117958) Study of AMG 199 in Subjects With MUC17-Positive Gastric and Gastroesophageal Junction Cancer. U.S. National Institutes of Health.
3	ClinicalTrials.gov (NCT04260191) Study of AMG 910 in Subjects With CLDN18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma. U.S. National Institutes of Health.