Details of the Drug

General Information of Drug (ID: DMX3ANZ)

• Drug Name: 3-Mercuri-4-Aminobenzenesulfonamide
• Synonyms: 3-Mercuri-4-Aminobenzenesulfonamide; (2-amino-5-sulfamoylphenyl)mercury; AC1L4WFQ; SCHEMBL678556; CTK7D7985; CHEBI:49484; [2-amino-5-(sulfamoyl)phenyl]mercury; DB04203

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight; 371.79
  Logarithm of the Partition Coefficient; Not Available
  Rotatable Bond Count; 1
  Hydrogen Bond Donor Count; 2
  Hydrogen Bond Acceptor Count; 4
• Chemical Identifiers:
  Formula: C6H7HgN2O2S
  IUPAC Name: (2-amino-5-sulfamoylphenyl)mercury
  Canonical SMILES: C1=CC(=C(C=C1S(=O)(=O)N)[Hg])N
  InChI: InChI=1S/C6H7N2O2S.Hg/c7-5-1-3-6(4-2-5)11(8,9)10;/h1,3-4H,7H2,(H2,8,9,10)
  InChIKey: KGGLGSZFQPTPPT-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 193512
  ChEBI ID: CHEBI:49484
  DrugBank ID: DB04203
  TTD ID: D0A2PD

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbonic anhydrase II (CA-II)	TTANPDJ	CAH2_HUMAN	Inhibitor	[1]

Molecular Expression Atlas of This Drug

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Carbonic anhydrase II (CA-II)	DTT	CA2	7.95E-08	0.52	0.33

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.