Details of the Drug

General Information of Drug (ID: DMXFY18)

Drug Name

EZN-3042

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 1	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Apoptosis inhibitor survivin (BIRC5)	TTTPU1G	BIRC5_HUMAN	Modulator	[2]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Solid tumour/cancer

ICD Disease Classification

2A00-2F9Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Apoptosis inhibitor survivin (BIRC5)	DTT	BIRC5	1.67E-190	1.63	5.29

Molecular Expression Atlas (MEA)

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References

1	2011 Pipeline of Santaris Pharma.
2	SPC3042: a proapoptotic survivin inhibitor.Mol Cancer Ther.2008 Sep;7(9):2736-45.