Details of the Drug

General Information of Drug (ID: DMXPFYZ)

• Drug Name: 2-fluorophenylboronic acid
• Synonyms: 2-Fluorophenylboronic acid; 1993-03-9; (2-fluorophenyl)boronic acid; 2-Fluorobenzeneboronic Acid; (2-fluorophenyl)boranediol; Boronic acid, B-(2-fluorophenyl)-; o-fluorophenylboronic acid; 2-fluorophenyl boronic acid; 2-fluoro-phenyl-boronic acid; BORONIC ACID, (2-FLUOROPHENYL)-; MFCD00674013; 2-Fluorophenylboronic acid, 98%; 34-03-7; PubChem1856; 2-Fluorophenylboronicacid; o-fluorobenzeneboronic acid; ACMC-1BR1I; o -Fluorophenylboronic acid; 2-fluoro-phenylboronic acid; AC1MC0Y0; 2-fluoro phenylboronic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight; 139.92
  Logarithm of the Partition Coefficient; Not Available
  Rotatable Bond Count; 1
  Hydrogen Bond Donor Count; 2
  Hydrogen Bond Acceptor Count; 3
• Chemical Identifiers:
  Formula: C6H6BFO2
  IUPAC Name: (2-fluorophenyl)boronic acid
  Canonical SMILES: B(C1=CC=CC=C1F)(O)O
  InChI: InChI=1S/C6H6BFO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4,9-10H
  InChIKey: QCSLIRFWJPOENV-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 2734354
  TTD ID: D0U7RS

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fatty acid amide hydrolase (FAAH)	TTDP1UC	NOUNIPROTAC	Inhibitor	[1]

Molecular Expression Atlas of This Drug

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Fatty acid amide hydrolase (FAAH)	DTT	NO-GeName	2.65E-01	0.02	0.1

References

• [1] Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase. J Med Chem. 2008 Nov 27;51(22):7057-60.