Details of the Drug

General Information of Drug (ID: DMXVIQN)

Drug Name

MOR-103

Synonyms

MOR-04357; Antibody (inflammation), MorphoSys; GM-CSF antibody (rheumatoid arthritis), MorphoSys; MOR-103 (rheumatoid arthritis), MorphoSys; GM-CSF antibody (iv infusion, inflammation), MorphoSys/Galapagos

Indication

Disease Entry	ICD 11	Status	REF
Multiple sclerosis	8A40	Phase 1/2	[1]
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Drug Type

Antibody

Cross-matching ID

TTD ID: D05ORA

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
GMCSFR-alpha (CSF2RA)	TT6MP2Z	CSF2R_HUMAN	Not Available	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT01023256) Safety and Preliminary Efficacy of MOR103 in Patients With Active Rheumatoid Arthritis. U.S. National Institutes of Health.
2	MOR103, a human monoclonal antibody to granulocyte-macrophage colony-stimulating factor, in the treatment of patients with moderate rheumatoid arthritis: results of a phase Ib/IIa randomised, double-blind, placebo-controlled, dose-escalation trial. Ann Rheum Dis. 2015 Jun;74(6):1058-64.