Details of the Drug

General Information of Drug (ID: DMY3J0B)

Drug Name

(+/-)-cis-2-CAMP

Synonyms

215597-45-8; 2-(Aminomethyl)cyclopropanecarboxylic acid; 2-(aminomethyl)cyclopropane-1-carboxylic acid; Cyclopropanecarboxylicacid, 2-(aminomethyl)-; (plusmn)-cis-2-CAMP; AC1N3MNT; SCHEMBL3943045; GTPL4067; CHEMBL284310; CTK1A0098; BDBM50087269; AKOS006277884; KB-163238; (cis)-2-Aminomethyl-cyclopropanecarboxylic acid; A29700; (trans)-2-Aminomethyl-cyclopropanecarboxylic acid; (+)-2-(aminomethyl)-cyclopropane-1-carboxylic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

#Ro5 Violations (Lipinski): 1

Molecular Weight (mw)

115.13

Logarithm of the Partition Coefficient (xlogp)

-3.1

Rotatable Bond Count (rotbonds)

2

Hydrogen Bond Donor Count (hbonddonor)

2

Hydrogen Bond Acceptor Count (hbondacc)

3

Chemical Identifiers

Formula: C5H9NO2
IUPAC Name: 2-(aminomethyl)cyclopropane-1-carboxylic acid
Canonical SMILES: C1C(C1C(=O)O)CN
InChI: InChI=1S/C5H9NO2/c6-2-3-1-4(3)5(7)8/h3-4H,1-2,6H2,(H,7,8)
InChIKey: QUFMERRXRMSAPZ-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 4067175
TTD ID: D0WV8K

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
GABA(A) receptor rho1 (GABRR1)	TT6XFEU	GBRR1_HUMAN	Agonist	[2]
GABA(A) receptor rho2 (GABRR2)	TTQMXLS	GBRR2_HUMAN	Agonist	[3]
GABA(A) receptor rho3 (GABRR3)	TT4N6D8	GBRR3_HUMAN	Agonist	[4]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4067).
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 420).
3	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 421).
4	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 422).