Details of the Drug

General Information of Drug (ID: DMY6PMJ)

Drug Name

ADC-9971

Synonyms

ADS-9971; CRTh2 antagonist (oral, COPD/allergic asthma/allergic rhinitis), Argenta Discovery; Prostaglandin D2 receptor antagonist (oral, allergic asthma/allergic rhinitis/COPD), Argenta Discovery

Indication

Disease Entry	ICD 11	Status	REF
Allergic rhinitis	CA08.0	Investigative	[1]
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Cross-matching ID

TTD ID: D0U3YW

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostaglandin D2 receptor 2 (PTGDR2)	TTQDMX5	PD2R2_HUMAN	Antagonist	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

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Molecular Expression Atlas of This Drug

The Studied Disease

Allergic rhinitis

ICD Disease Classification

CA08.0

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Prostaglandin D2 receptor 2 (PTGDR2)	DTT	PTGDR2	6.11E-02	-0.15	-0.25

Molecular Expression Atlas (MEA)

MEA Detail

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 339).