Details of the Drug

General Information of Drug (ID: DMZ07H6)

• Drug Name: Phenyl 4-(hexyloxy)phenylcarbamate
• Synonyms: phenyl 4-(hexyloxy)phenylcarbamate; CHEMBL599181

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 1:
  Molecular Weight (mw); 313.4
  Logarithm of the Partition Coefficient (xlogp); 5.6
  Rotatable Bond Count (rotbonds); 9
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 3
• Chemical Identifiers:
  Formula: C19H23NO3
  IUPAC Name: phenyl N-(4-hexoxyphenyl)carbamate
  Canonical SMILES: CCCCCCOC1=CC=C(C=C1)NC(=O)OC2=CC=CC=C2
  InChI: InChI=1S/C19H23NO3/c1-2-3-4-8-15-22-17-13-11-16(12-14-17)20-19(21)23-18-9-6-5-7-10-18/h5-7,9-14H,2-4,8,15H2,1H3,(H,20,21)
  InChIKey: ORPQZENLUNAGOE-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 20872832
  TTD ID: D0GM1P

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fatty acid amide hydrolase (FAAH)	TTDP1UC	NOUNIPROTAC	Inhibitor	[1]

Molecular Expression Atlas of This Drug

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Fatty acid amide hydrolase (FAAH)	DTT	NO-GeName	2.65E-01	0.02	0.1

References

• [1] Oxime carbamate--discovery of a series of novel FAAH inhibitors. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1272-7.