Details of the Drug

General Information of Drug (ID: DMZILNC)

Drug Name

3,3'-Pyridine-2,5-diyldiphenol

Synonyms

SCHEMBL1181050; CHEMBL460182; BDBM25865; 3,3'-(2,5-Pyridinediyl)bisphenol; ZINC40865361; hydroxyphenyl substituted pyridine, 37

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

263.29

Logarithm of the Partition Coefficient (xlogp)

3.4

Rotatable Bond Count (rotbonds)

2

Hydrogen Bond Donor Count (hbonddonor)

2

Hydrogen Bond Acceptor Count (hbondacc)

3

Chemical Identifiers

Formula: C17H13NO2
IUPAC Name: 3-[6-(3-hydroxyphenyl)pyridin-3-yl]phenol
Canonical SMILES: C1=CC(=CC(=C1)O)C2=CN=C(C=C2)C3=CC(=CC=C3)O
InChI: InChI=1S/C17H13NO2/c19-15-5-1-3-12(9-15)14-7-8-17(18-11-14)13-4-2-6-16(20)10-13/h1-11,19-20H
InChIKey: GWBPLTAHNKSFLG-UHFFFAOYSA-N

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Estradiol 17 beta-dehydrogenase 1 (17-beta-HSD1)	TTIWB6L	DHB1_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Design, synthesis, biological evaluation and pharmacokinetics of bis(hydroxyphenyl) substituted azoles, thiophenes, benzenes, and aza-benzenes as p... J Med Chem. 2008 Nov 13;51(21):6725-39.