Details of the Drug

General Information of Drug (ID: DMZO1FJ)

Drug Name
TIP
Synonyms oxide; 16833-27-5; Oxide anion; Oxide ion; Atomic oxygen(2-); Oxygen, ion(O2-); oxide(2-); AC1L4Q4G; AC1Q22UN; CTK4D2966; CHEBI:29356; O(2-)
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 15.999
Logarithm of the Partition Coefficient (xlogp) -0.5
Rotatable Bond Count (rotbonds) 0
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 1
Chemical Identifiers
Formula
O-2
IUPAC Name
oxygen(2-)
Canonical SMILES
[O-2]
InChI
InChI=1S/O/q-2
InChIKey
AHKZTVQIVOEVFO-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
190217
ChEBI ID
CHEBI:29356
CAS Number
16833-27-5
TTD ID
D0LL4C

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Opioid receptor delta (OPRD1) TT27RFC OPRD_HUMAN Antagonist [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Opioid receptor delta (OPRD1) DTT OPRD1 5.52E-01 0.03 0.23
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 The TIPP opioid peptide family: development of delta antagonists, delta agonists, and mixed mu agonist/delta antagonists. Biopolymers. 1999;51(6):411-25.