Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TT0R12H)

DTT Name	Neuron-specific vesicular protein calcyon (CALY)
Synonyms	Neuronspecific vesicular protein calcyon; CALY
Gene Name	CALY
DTT Type	Discontinued target	[1]
Related Disease	Pain [ICD-11: MG30-MG3Z]
UniProt ID	CALY_HUMAN
TTD ID	T30802
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD QQNFPDLEGQRLNCSHPEEGRRLPTARMIAFAMALLGCVLIMYKAIWYDQFTCPDGFLLR HKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEERKGPT QAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ
Function	Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.
KEGG Pathway	( )

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Discontinued Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CY-208243	DMP8TKA	Pain	MG30-MG3Z	Discontinued in Phase 2	[1]
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1 Investigative Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Apomorphine SL	DMPH7EO	Discovery agent	N.A.	Investigative	[2]
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References

1	Dopamine D1 receptor agonists induce penile erections in rats. Eur J Pharmacol. 2003 Jan 26;460(1):71-4.
2	Dopamine and sexual function. Int J Impot Res. 2001 Aug;13 Suppl 3:S18-28.