Details of the Drug

General Information of Drug (ID: DMPH7EO)

Drug Name

Apomorphine SL

Synonyms

Apomorphine HCl; Apomorphine chloride; (R)-(-)-Apomorphine hydrochloride; Apomorphinium chloride; Apomorphin hydrochlorid; 314-19-2; pomorphini hydrochloridum; Apomorphinum hydrochloricum; N-Methylnorapomorphine hydrochloride; UNII-9K13MD7A0D; (-)-Apomorphinium hydrochloride; Apomorphine hydrochloride anhydrous; EINECS 206-243-0; NSC 11442; 9K13MD7A0D; 6a-beta-Aporphine-10,11-diol, hydrochloride; 6abeta-Noraporphine-10,11-diol, 6-methyl-, hyd

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski):
0

Molecular Weight

303.8

Topological Polar Surface Area

Not Available

Rotatable Bond Count

0

Hydrogen Bond Donor Count

3

Hydrogen Bond Acceptor Count

3

Chemical Identifiers

Formula: C17H18ClNO2
IUPAC Name: (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrochloride
Canonical SMILES: CN1CCC2=C3[C@H]1CC4=C(C3=CC=C2)C(=C(C=C4)O)O.Cl
InChI: InChI=1S/C17H17NO2.ClH/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12;/h2-6,13,19-20H,7-9H2,1H3;1H/t13-;/m1./s1
InChIKey: SKYZYDSNJIOXRL-BTQNPOSSSA-N

Cross-matching ID

PubChem CID: 9410
CAS Number: 314-19-2
TTD ID: D0B6QP

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Neuron-specific vesicular protein calcyon (CALY)	TT0R12H	CALY_HUMAN	Activator	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Dopamine and sexual function. Int J Impot Res. 2001 Aug;13 Suppl 3:S18-28.
2	Dopamine D1 receptor agonists induce penile erections in rats. Eur J Pharmacol. 2003 Jan 26;460(1):71-4.