Details of the Drug Therapeutic Target (DTT)
General Information of Drug Therapeutic Target (DTT) (ID: TT2FX8W)
DTT Name | Keratin 6A messenger RNA (KRT6A mRNA) | ||||
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Synonyms |
Type-II keratin Kb6 (mRNA); Keratin-6A (mRNA); Keratin, type II cytoskeletal 6A (mRNA); KRT6D (mRNA); K6A (mRNA); Hom s 5 (mRNA); Cytokeratin-6D (mRNA); Cytokeratin-6A (mRNA); CK-6D (mRNA); CK-6A (mRNA)
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Gene Name | KRT6A | ||||
DTT Type |
Clinical trial target
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BioChemical Class |
mRNA target
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UniProt ID | |||||
TTD ID | |||||
3D Structure | |||||
Sequence |
MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRS
LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDK VRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELR GMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY EELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMAL KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG VGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLS SVGGGSSTIKYTTTSSSSRKSYKH |
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Function |
Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. Epidermis-specific type I keratin involved in wound healing.
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Reactome Pathway | |||||
Molecular Interaction Atlas (MIA) of This DTT
Molecular Interaction Atlas (MIA) | ||||||||||||||||||||||||||||
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1 Clinical Trial Drug(s) Targeting This DTT
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