Details of the Drug

General Information of Drug (ID: DMJ3KPO)

Drug Name

TD-101

Indication

Disease Entry	ICD 11	Status	REF
Flavivirus infection	1C80	Phase 2	[1]
Pachyonychia	EE10.3	Phase 1	[2]
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Drug Type

siRNA drug

Cross-matching ID

Repurposed Drugs (RPD)

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Keratin 6A messenger RNA (KRT6A mRNA)	TT2FX8W	K2C6A_HUMAN	Not Available	[3]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	ClinicalTrials.gov (NCT00716014) Study of TD101, a Small Interfering RNA (siRNA) Designed for Treatment of Pachyonychia Congenita. U.S. National Institutes of Health.
3	First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder. Mol Ther. 2010 Feb;18(2):442-6.