Details of the Drug Therapeutic Target (DTT)
General Information of Drug Therapeutic Target (DTT) (ID: TTBKQL3)
| DTT Name | Trypanosoma Dihydrolipoamide dehydrogenase (Trypano LPD) | ||||
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| Synonyms | Lipoamide dehydrogenase; LipDH; LPD; Glycine cleavage system L protein; Dihydrolipoamide dehydrogenase | ||||
| Gene Name | Trypano LPD | ||||
| DTT Type |
Literature-reported target
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[1] | |||
| BioChemical Class |
Sulfur donor oxidoreductase
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| UniProt ID | |||||
| TTD ID | |||||
| 3D Structure | |||||
| Sequence |
MFRRCAVKLNPYDVVVIGGGPGGYVASIKAAQLGMKTACVEKRGALGGTCLNVGCIPSKA
LLHATHVYHDAHANFARYGLMGGEGVTMDSAKMQQQKERAVKGLTGGVEYLFKKNKVTYY KGEGSFETAHSIRVNGLDGKQEMFETKKTIIATGSEPTELPFLPFDEKVVLSSTGALALP RVPKTMVVIGGGVIGLELGSVWARLGAKVTVVEFAPRCAPTLDEDVTNALVGALAKNEKM KFMTSTKVVGGTNNGDSVSLEVEGKNGKRETVTCEALLVSVGRRPFTGGLGLDKINVAKN ERGFVKIGDHFETSIPDVYAIGDVVDKGPMLAHKAEDEGVACAEILAGKPGHVNYGVIPA VIYTMPEVASVGKSEEELKKEGVAYKVGKFPFNANSRAKAVSTEDGFVKVLVDKATDRIL GVHIVCTTAGELIGEACLAMEYGASSEDVGRTCHAHPTMSEALKEACMALVAKTINF |
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| Function | Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. | ||||
Molecular Interaction Atlas (MIA) of This DTT
| Molecular Interaction Atlas (MIA) | ||||||||||||||||||||||||||||||||||
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2 Investigative Drug(s) Targeting This DTT
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