Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTHL6YX)

DTT Name Progesterone (PG)
Gene Name NO-GeName
DTT Type
Clinical trial target
 [1]
Related Disease
Breast cancer [ICD-11: 2C60-2C6Y]
UniProt ID
NOUNIPROTAC
TTD ID
T59955

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
1 Clinical Trial Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
BAY 86-5044 DMRZLU4 Breast cancer 2C60-2C65 Phase 2 [1]
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1 Discontinued Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
ORG-33628 DMWZXF7 Contraception QA21 Discontinued in Phase 2 [2]
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References

1 Randomized phase II study of lonaprisan as second-line therapy for progesterone receptor-positive breast cancer. Ann Oncol. 2013 Oct;24(10):2543-8.
2 ORG 33628 and ORG 31710 to control vaginal bleeding in progestin-only contraceptive regimens. Semin Reprod Med. 2005 Feb;23(1):101-11.