General Information of Drug Therapeutic Target (DTT) (ID: TTI6FFX)

DTT Name Glial fibrillary acidic protein messenger RNA (GFAP mRNA)
Synonyms GFAP (mRNA)
Gene Name GFAP
DTT Type
Clinical trial target
[1]
BioChemical Class
mRNA target
UniProt ID
GFAP_HUMAN
TTD ID
T63228
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNA
GFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAEL
RELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEAT
LARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRT
QYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLR
GTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALD
IEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEV
IKESKQEHKDVM
Function GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
KEGG Pathway
2670 (hsa )
Reactome Pathway
( )
(R-HSA-1251985 )
(R-HSA-9613829 )

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
1 Clinical Trial Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
ION373 DMHI0KL Alexander disease 8A44.2 Phase 3 [1]
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References

1 Clinical pipeline report, company report or official report of Ionis