Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTTPDRC)

DTT Name	Pseudomonas Psl exopolysaccharide (Pseudo pslG)
Synonyms	PslG
Gene Name	Pseudo pslG
DTT Type	Clinical trial target	[1]
UniProt ID	Q9I1N2_PSEAE
TTD ID	T42882
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MARKGLYLGGSALLLAVVLLLVFWGRPADAEIQVLKAPRAVVWKDFLGVNAQFLWFSPER YNKQIDRLQDLGLEWVRLDLHWDRLETAEDQYQLASLDQLVKDLEARQLKSVFYLVGSAR FITTAPFYSPFQDQYPPRDPEVFARRMAMLSQRYPSVAAWQVWNEPNLIGFWRPKADPEG YAKLLQASTIALRMVDPEKPVVSAGMAFFSEMPDGRTMFDALGHLGVESLGTIATYHPYT QLPEGNYPWNLDFVSHANQINRALRNAGVPAIWSTEWGWSAYKGPKELQDIIGVEGQADY VLRRLALMSALDYDRIFLFTLSDLDQRASVRDRDYGLLDLDANPKPVYLALQRFLKVTGP KLRPADPPVTEDLPDGSFSIGWTREDGRNVWLFWSARGGNVRLPKLKEATLHDPLSGKVT PLSGSDGLEVPVKSSLQMLVWE
Function	A extracellular matrix component of P. aeruginosa biofilms. A galactose-rich and mannose-rich exopolysaccharide.
KEGG Pathway	Biofilm formation - Pseudomonas aeruginosa (pae02025 )
BioCyc Pathway	PAER208964:G1FZ6-2277-MON

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Clinical Trial Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
MEDI3902	DMOXKIC	Ventilator-associated pneumonia	PK81.0	Phase 2	[1]
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References

1	A multifunctional bispecific antibody protects against Pseudomonas aeruginosa. Sci Transl Med. 2014 Nov 12;6(262):262ra155.