Details of the Drug

General Information of Drug (ID: DMOXKIC)

Drug Name

MEDI3902

Indication

Disease Entry	ICD 11	Status	REF
Ventilator-associated pneumonia	PK81.0	Phase 2	[1]
Pseudomonas infection	1B92	Phase 1	[2]
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Drug Type

Antibody

Cross-matching ID

Repurposed Drugs (RPD)

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Pseudomonas PcrV protein type III (Pseudo pcrV)	TTLK9NJ	O30527_PSEAI	Not Available	[3]
Pseudomonas Psl exopolysaccharide (Pseudo pslG)	TTTPDRC	Q9I1N2_PSEAE	Not Available	[3]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT02696902) Effort to Prevent Nosocomial Pneumonia Caused by Pseudomonas Aeruginosa in Mechanically Ventilated Subjects
2	ClinicalTrials.gov (NCT02255760) Phase 1 Randomized Double-blind Placebo Controlled Study to Evaluate Safety and PK of MEDI3902 in Healthy Adults. U.S. National Institutes of Health.
3	A multifunctional bispecific antibody protects against Pseudomonas aeruginosa. Sci Transl Med. 2014 Nov 12;6(262):262ra155.