Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTWC6MY)

DTT Name Protein tyrosine phosphatase (PTP)
Synonyms PTPase; PTPN
Gene Name PTP
DTT Type
Clinical trial target
 [1]
BioChemical Class
Phosphoric monoester hydrolase
UniProt ID
NOUNIPROTAC
TTD ID
T09227

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
2 Clinical Trial Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
INCB13739 DMLQ3PO Type-2 diabetes 5A11 Phase 2a [1]
KP-100 DML29RF Type-1 diabetes 5A10 Phase 1/2 [2]
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2 Investigative Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Diamide DMOCQ9J Discovery agent N.A. Investigative [1]
Pervanadate DM873BS Discovery agent N.A. Investigative [1]
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References

1 Induction of endothelial cell surface adhesion molecules by tumor necrosis factor is blocked by protein tyrosine phosphatase inhibitors: role of the nuclear transcription factor NF-kappa B. Eur J Immunol. 1997 Sep;27(9):2172-9.
2 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010512)