General Information of Drug Inactive Ingredient (DIG) (ID: E00125)

DIG Name
Tromethamine
Synonyms
Trometamol; TROMETHAMINE; 77-86-1; Tris; Tris(Hydroxymethyl)aminomethane; Tham; 2-Amino-2-(hydroxymethyl)propane-1,3-diol; Trisamine; 2-Amino-2-(hydroxymethyl)-1,3-propanediol; Trizma; Tris buffer; Tris base; Tromethane; Trisaminol; 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-; Pehanorm; Talatrol; Trisamin; Trispuffer; Tutofusin tris; Apiroserum Tham; Tris-steril; Addex-tham; Tris-base; Tris, free base; Trimethylolaminomethane; Tris Amino; Aminotrimethylolmethane; Aminotris(hydroxymethyl)methane; THAM-E; Tris (buffering agent); Tromethanmin; Tris(hydroxymethyl)methanamine; Tris(hydroxymethyl)methylamine; Trometamole; Trizma base; 2-Amino-2-methylol-1,3-propanediol; Tris-hydroxymethylaminomethane; Tri(hydroxymethyl)aminomethane; 2-Amino-2-hydroxymethyl-1,3-propanediol; Tris-Amino; Methylamine, 1,1,1-tris(hydroxymethyl)-; NSC 6365; 2-(Hydroxymethyl)-2-amino-1,3-propanediol; UNII-023C2WHX2V; Tris-hydroxymethyl-aminomethan; Methanamine, 1,1,1-tris(hydroxymethyl)-; MFCD00004679; 023C2WHX2V; CHEBI:9754; tris(hydroxymethyl) aminomethane; Tris(Hydroxymethyl)-Aminomethane; Tris-(hydroxymethyl)-aminomethane; NSC6365; NSC-6365; 1,1,1-tris(hydroxymethyl)methanamine; TRIS (tromethamine); NCGC00159412-02; NCGC00159412-04; Tris buffertris-hydroxymethyl-aminomethan; Tromethamolum; DSSTox_CID_3723; trishydroxymethylaminomethane; WLN: Q1XZ1Q1Q; DSSTox_RID_77165; DSSTox_GSID_23723; (tris(hydroxymethyl)aminomethane); [tris(hydroxymethyl)aminomethane]; Caswell No. 036; Trometamolum; 1, 2-amino-2-(hydroxymethyl)-; Triladyl; Trigmo base; MFCD00132476; Methanamine,1,1-tris(hydroxymethyl)-; Methylamine,1,1-tris(hydroxymethyl)-; Trometamolum [INN-Latin]; tris(hydroxymethyl)amino methane; CAS-77-86-1; Tris(hydroxymethyl)aminomethane, >=99.8%; 2-amino-2-(hydroxymethyl)-1, 3-propanediol; HSDB 3408; EINECS 201-064-4; Tris(hydroxymethyl)aminomethane, Electrophoresis Grade; Tris-Mg(II)-KCl Buffer; Tromethamine [USAN:USP]; EPA Pesticide Chemical Code 083901; Tris(hydroxymethyl)aminomethane, 99+%, for biochemistry; Tris-hydroxymethyl-aminomethan [German]; Trometamina; Tromethamin; Aminotri(hydroxymethyl)methane; Tribase; tris-buffer; tris-amine; AI3-03948; Tro.meta.mole; Tris(hydroxymethyl)aminomethane, 99.8%, for analysis, biochemical grade; Tro.meta.mol; Tris(hydroxymethyly)amino methane; 1gng; 83147-39-1; Tris(hydroxymethyl)aminomethane, 99.85%, for molecular biology, DNAse, RNAse and Protease free; Trometamol [INN]; TRS; Tromethamine (USP); TRIS Ultrapure, EP; 1h4n; Trometamol (JAN/INN); Tris-[d11]; Tris-Magnesium(II)-Potassium Chloride Buffer; SCHEMBL975; trishydroxymethylmethylamine; THAM (TN); Buffer Salt, pH 10.5; EC 201-064-4; Tri(hydroxymethyl)methylamin; NCIOpen2_000263; NCIOpen2_001720; 2-Amino-2-hydroxymethyl-1,3-propanediol solution; Oprea1_677781; trishydroxymethyl aminomethane; tris-hydroxymethyl-methylamine; B-TRIS500; MLS000028643; ARONIS23912; tris hydroxymethyl aminomethane; Tris (hydroxymethyl)aminoethane; GTPL7328; tris (hydroxymethyl)aminomethane; CHEMBL1200391; DTXSID2023723; tris (hydroxymethyl) methylamine; tris (hydroxymethyl) aminomethane; Tris(2-hydroxymethyl)aminomethane; 2-Amino-2-hydroxymethylpropanediol; HMS3652L05; HMS3885H09; tris-(hydroxymethyl)-amino-methane; ZINC896695; 2-amino-2-hydroxymethyl-propane-1; Tris-Base, molecular biology grade; BCP05578; HY-D0227; NSC65434; STR03166; Tox21_111645; Tox21_201646; Tox21_303167; BBL000011; NSC-65434; s4176; SBB006714; STK379529; 2-amino-2-methylol-propane-1,3-diol; AKOS000121321; Tox21_111645_1; AM90366; CCG-214012; CS-W018524; DB03754; MCULE-7300085951; NE10342; Trizma(R) base, >=99.0% (T); ATX Tris buffer, ready-to-use solution; Tris(hydroxymethyl)aminomethane, >=99%; NCGC00159412-03; NCGC00159412-05; NCGC00257164-01; NCGC00259195-01; TRIS, 0.5M buffer solution, pH 6.8; TRIS, 0.5M buffer solution, pH 7.2; TRIS, 0.5M buffer solution, pH 7.4; TRIS, 0.5M buffer solution, pH 7.5; TRIS, 0.5M buffer solution, pH 8.0; TRIS, 0.5M buffer solution, pH 8.5; TRIS, 0.5M buffer solution, pH 8.6; TRIS, 0.5M buffer solution, pH 8.8; TRIS, 0.5M buffer solution, pH 9.0; TRIS, 0.5M buffer solution, pH 9.5; TRIS, 1.0M buffer solution, pH 6.5; TRIS, 1.0M buffer solution, pH 7.4; TRIS, 1.0M buffer solution, pH 7.6; TRIS, 1.0M buffer solution, pH 7.8; TRIS, 1.0M buffer solution, pH 8.2; TRIS, 1.0M buffer solution, pH 8.4; TRIS, 1.0M buffer solution, pH 8.6; TRIS, 1.0M buffer solution, pH 8.8; TRIS, 1.0M buffer solution, pH 9.0; AK-41163; BP-13394; SMR000059179; Tris(hydroxymethyl)aminomethane ACS grade; Tris(hydroxymethyl)aminomethane, ultrapure; 2-amino-2-[hydroxymethyl]-1,3-propandiol; DB-091324; DS-014869; Methanamine, 1, 1,1-tris(hydroxymethyl)-; Tris acidimetric, NIST(R) SRM(R) 723e; A0321; FT-0611014; ST51037436; SW219208-1; T6977; TRIS-buffered saline (TBS, 10X) pH 7.4; TRIS-buffered saline (TBS, 10X) pH 7.6; TRIS-buffered saline (TBS, 10X) pH 8.0; TRIS-buffered saline (TBS, 20X) pH 7.4; 2-(Hydroxymethyl)-2-amino-1, 3-propanediol; 2-amino-2-(hydroxyl-methyl)propane-1,3-diol; 2-amino-2-(hydroxymethyl) propane-1,3-diol; 2-Amino-2-(hydroxymethyl)-1,3-propanediol;; Tris-amino, Tromethane, Trometamol, Trisamine; Trizma(R) base, BioUltra, >=99.8% (T); Trizma(R) base, tested according to Ph.Eur.; Tromethamine, meets USP testing specifications; 1606-EP1441224A2; 1606-EP2269977A2; 1606-EP2269992A1; 1606-EP2270000A1; 1606-EP2270001A1; 1606-EP2270004A1; 1606-EP2270014A1; 1606-EP2270101A1; 1606-EP2270895A2; 1606-EP2272516A2; 1606-EP2272817A1; 1606-EP2272825A2; 1606-EP2272827A1; 1606-EP2272835A1; 1606-EP2272844A1; 1606-EP2272972A1; 1606-EP2272973A1; 1606-EP2275105A1; 1606-EP2275413A1; 1606-EP2275420A1; 1606-EP2275469A1; 1606-EP2277507A1; 1606-EP2277872A1; 1606-EP2277877A1; 1606-EP2277881A1; 1606-EP2277882A1; 1606-EP2278637A1; 1606-EP2280004A1; 1606-EP2280005A1; 1606-EP2280006A1; 1606-EP2280011A1; 1606-EP2280012A2; 1606-EP2280020A1; 1606-EP2280021A1; 1606-EP2281813A1; 1606-EP2281818A1; 1606-EP2281899A2; 1606-EP2284157A1; 1606-EP2284169A1; 1606-EP2286795A1; 1606-EP2287156A1; 1606-EP2287161A1; 1606-EP2287162A1; 1606-EP2287165A2; 1606-EP2287166A2; 1606-EP2289868A1; 1606-EP2289883A1; 1606-EP2289884A1; 1606-EP2289886A1; 1606-EP2289890A1; 1606-EP2289891A2; 1606-EP2289894A2; 1606-EP2292589A1; 1606-EP2292593A2; 1606-EP2292596A2; 1606-EP2292607A2; 1606-EP2292610A1; 1606-EP2292620A2; 1606-EP2295055A2; 1606-EP2295406A1; 1606-EP2295410A1; 1606-EP2295417A1; 1606-EP2295421A1; 1606-EP2295423A1; 1606-EP2295424A1; 1606-EP2295429A1; 1606-EP2295434A2; 1606-EP2295436A1; 1606-EP2295439A1; 1606-EP2295550A2; 1606-EP2298305A1; 1606-EP2298312A1; 1606-EP2298728A1; 1606-EP2298744A2; 1606-EP2298769A1; 1606-EP2298773A1; 1606-EP2298774A1; 1606-EP2298783A1; 1606-EP2299785A1; 1606-EP2301921A1; 1606-EP2301926A1; 1606-EP2301928A1; 1606-EP2301930A1; 1606-EP2301932A1; 1606-EP2301934A1; 1606-EP2301937A1; 1606-EP2301939A1; 1606-EP2302382A2; 1606-EP2302383A2; 1606-EP2305250A1; 1606-EP2305641A1; 1606-EP2305672A1; 1606-EP2305677A1; 1606-EP2305687A1; 1606-EP2305825A1; 1606-EP2306788A1; 1606-EP2306789A1; 1606-EP2308841A2; 1606-EP2308851A1; 1606-EP2308855A1; 1606-EP2308866A1; 1606-EP2308873A1; 1606-EP2308874A1; 1606-EP2308878A2; 1606-EP2311453A1; 1606-EP2311801A1; 1606-EP2311802A1; 1606-EP2311803A1; 1606-EP2311807A1; 1606-EP2311814A1; 1606-EP2311818A1; 1606-EP2314571A2; 1606-EP2314584A1; 1606-EP2314585A1; 1606-EP2316824A1; 1606-EP2316830A2; 1606-EP2316832A1; 1606-EP2316833A1; 1606-EP2371811A2; 1606-EP2371814A1; 1606-EP2374784A1; 1606-EP2374785A1; 3368-EP2269610A2; 3368-EP2270002A1; 3368-EP2270010A1; 3368-EP2272517A1; 3368-EP2272822A1; 3368-EP2277848A1; 3368-EP2281815A1; 3368-EP2284160A1; 3368-EP2284172A1; 3368-EP2289510A1; 3368-EP2289890A1; 3368-EP2295406A1; 3368-EP2295409A1; 3368-EP2301933A1; 3368-EP2301937A1; 3368-EP2305250A1; 3368-EP2305640A2; 3368-EP2305646A1; 3368-EP2305677A1; 3368-EP2305679A1; 3368-EP2305682A1; 3368-EP2308840A1; 3368-EP2308879A1; 3368-EP2311827A1; 3368-EP2311842A2; 3368-EP2314295A1; 3368-EP2314574A1; 3368-EP2314588A1; 3368-EP2314590A1; 3368-EP2316457A1; 3368-EP2316458A1; 3368-EP2316825A1; 3368-EP2316826A1; 3368-EP2316827A1; 3368-EP2316828A1; C07182; D00396; M02623; 23153-EP2270505A1; 23153-EP2272832A1; 23153-EP2281899A2; 23153-EP2284159A1; 23153-EP2287163A1; 23153-EP2289883A1; 23153-EP2292592A1; 23153-EP2295407A1; 23153-EP2298736A1; 23153-EP2298743A1; 23153-EP2298767A1; 23153-EP2298778A1; 23153-EP2305641A1; 23153-EP2305651A1; 23153-EP2305678A1; 23153-EP2305684A1; 23153-EP2308510A1; 23153-EP2308854A1; 23153-EP2314584A1; 23153-EP2314587A1; 27256-EP2272822A1; 27256-EP2314575A1; 42340-EP2305808A1; 42340-EP2308479A2; 42340-EP2311808A1; 42340-EP2311829A1; AB00443859_03; AB00443859_04; 111860-EP2292611A1; 111860-EP2298761A1; 116174-EP2289891A2; 116174-EP2298770A1; Q413961; Sigma 7-9(R), >=99% (titration), crystalline; SR-01000944234; Trizma(R) base, puriss. p.a., >=99.7% (T); J-610076; SR-01000944234-1; Trizma(R) base, >=99.9% (titration), crystalline; Trizma(R) base, Vetec(TM) reagent grade, >=99%; W-104296; Tris(hydroxymethyl)aminomethane, 99.8%, ACS reagent; Tris(hydroxymethyl)aminomethane, ACS reagent, 99.9%; TRIS-buffered saline (TBS, 10X, low salt) pH 8.0; 4-Anilino-1-(2-hydroxyethylamino)anthracene-9,11-dione; F0001-1979; Tris(hydroxymethyl)aminomethane, ACS reagent, >=99.8%; Tris(hydroxymethyl)aminomethane, Molecular Biology Grade; TRIS-buffered saline (TBS, 10X, high salt) pH 7.4; Z1317839150; Tris(hydroxymethyl)aminomethane, p.a., ACS reagent, 99.8%; Tris(hydroxymethyl)aminomethane, ultrapure grade, >=99.9%; TRIS-buffered saline (TBS, 10X), with 1% Triton X-100; Trizma(R) base, puriss. p.a., buffer substance, >=99.5%; Trometamol, European Pharmacopoeia (EP) Reference Standard; Tris(hydroxymethyl)aminomethane, JIS special grade, >=99.0%; TRIS, 1.0M buffer solution, pH 7.0, 0.2 micron filtered; TRIS, 1.0M buffer solution, pH 8.5, 0.2 micron filtered; TRIS, 1.0M buffer solution, pH 9.0, 0.2 micron filtered; TRIS-buffered saline (TBS, 10X) pH 7.4, for Western blot; Trizma(R) base, anhydrous, free-flowing, Redi-Dri(TM), >=99.9%; Trizma(R) base, BioUltra, for molecular biology, >=99.8% (T); Tromethamine, United States Pharmacopeia (USP) Reference Standard; Trizma(R) base, cell culture tested, >=99.9% (titration), crystalline; Trizma(R) base, BioXtra, pH 10.5-12.0 (1 M in H2O), >=99.9% (titration); Trizma(R) base, Primary Standard and Buffer, >=99.9% (titration), crystalline; Tromethamine, Pharmaceutical Secondary Standard; Certified Reference Materi
DIG Function
Alkalizing agent; Buffering agent; Emulsifying agent
Formula
C4H11NO3
Canonical SMILES
C(C(CO)(CO)N)O
InChI
1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
InChIKey
LENZDBCJOHFCAS-UHFFFAOYSA-N
Physicochemical Properties Molecular Weight 121.14 Topological Polar Surface Area 86.7
XlogP -2.9 Complexity 54
Heavy Atom Count 8 Rotatable Bond Count 3
Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 4

Full List of Drug(s) Co-administrated with This DIG

4 Approved Drug(s) Co-administrated with This DIG
Drug Name Drug ID Indication Formulation Name Formulation ID
Atorvastatin DMF28YC Acute coronary syndrome [BA41] Atorvastatin 10 mg tablet F01973
Carboprost Tromethamine DMS3508 Abortion [JA00] Carboprost Tromethamine eq 0.25mg base/ml injectable F23102
Fluorouracil DMUM7HZ Adenocarcinoma [2D40] Fluorouracil 2% solution F23753
Pegvaliase DM6NZ2P Phenylketonuria [5C50.0] Pegvaliase 10mg/0.5 ml Injection F24305
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