Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE073H6)

• DME Name: Prostaglandin G/H synthase 1 (COX-1) DME Info
• Gene Name: PTGS1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.43E-05	4.18E-01	6.74E-01
Alopecia	ED70	Skin from scalp	5.55E-02	2.50E-01	4.84E-01
Alzheimer's disease	8A20	Entorhinal cortex	3.97E-03	1.56E-01	4.33E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.13E-01	2.70E-01	5.97E-01
Aortic stenosis	BB70	Calcified aortic valve	5.42E-01	4.22E-01	4.02E-01
Apnea	7A40	Hyperplastic tonsil	5.40E-01	7.90E-01	7.97E-01
Arthropathy	FA00-FA5Z	Peripheral blood	4.14E-02	3.87E-01	8.07E-01
Asthma	CA23	Nasal and bronchial airway	5.11E-09	5.07E-01	9.56E-01
Atopic dermatitis	EA80	Skin	4.11E-05	-3.71E-01	-1.66E+00
Autism	6A02	Whole blood	6.65E-02	2.29E-01	4.16E-01
Autoimmune uveitis	9A96	Peripheral monocyte	1.10E-01	3.78E-01	1.92E+00
Autosomal dominant monocytopenia	4B04	Whole blood	3.28E-01	2.30E-01	5.74E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.03E-03	-1.94E-01	-4.45E-01
Batten disease	5C56.1	Whole blood	6.89E-01	1.82E-01	2.17E-01
Behcet's disease	4A62	Peripheral blood	8.88E-01	-2.70E-02	-6.39E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.89E-01	-1.32E-01	-2.24E-01
Bladder cancer	2C94	Bladder tissue	7.05E-03	-1.89E+00	-1.28E+00
Breast cancer	2C60-2C6Z	Breast tissue	9.97E-01	-9.62E-02	-1.94E-01
Cardioembolic stroke	8B11.20	Whole blood	3.86E-01	-2.04E-01	-4.61E-01
Cervical cancer	2C77	Cervical tissue	6.69E-03	-9.05E-01	-1.05E+00
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.32E-02	5.08E-01	7.11E-01
Chronic hepatitis C	1E51.1	Whole blood	5.16E-01	6.87E-03	1.28E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.04E-01	-8.41E-02	-1.63E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	8.46E-05	2.14E-01	6.23E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.58E-01	9.51E-02	8.30E-01
Colon cancer	2B90	Colon tissue	1.24E-37	-8.46E-01	-1.61E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.88E-01	9.39E-01	1.19E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	9.45E-01	-6.62E-02	-9.47E-02
Endometriosis	GA10	Endometrium tissue	2.17E-01	6.85E-01	4.32E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	1.39E-01	-3.44E-02	-1.13E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.71E-04	1.92E+00	2.05E+00
Gastric cancer	2B72	Gastric tissue	3.42E-01	-3.96E-01	-6.06E-01
Glioblastopma	2A00.00	Nervous tissue	1.72E-63	7.14E-01	1.48E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	2.54E-09	-1.15E+00	-2.94E+01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	4.59E-01	-3.48E-01	-1.94E-01
Head and neck cancer	2D42	Head and neck tissue	6.06E-12	1.05E+00	7.98E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.53E-01	-1.03E-01	-6.11E-01
Huntington's disease	8A01.10	Whole blood	3.48E-01	4.02E-02	8.75E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.71E-02	7.25E-01	2.30E+00
Immunodeficiency	4A00-4A20	Peripheral blood	2.56E-02	6.56E-02	7.65E-01
Influenza	1E30	Whole blood	9.98E-02	-9.07E-01	-1.93E+00
Interstitial cystitis	GC00.3	Bladder tissue	2.79E-01	1.05E+00	1.20E+00
Intracranial aneurysm	8B01.0	Intracranial artery	6.28E-05	1.18E+00	2.10E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	4.10E-01	-3.87E-02	-1.51E-01
Ischemic stroke	8B11	Peripheral blood	2.89E-01	1.83E-01	3.08E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.53E-09	4.11E-01	8.73E-01
Lateral sclerosis	8B60.4	Skin	2.46E-01	7.05E-01	9.44E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	8.19E-01	-1.40E-02	-9.21E-02
Liver cancer	2C12.0	Liver tissue	2.45E-08	-4.69E-01	-1.88E+00
Liver failure	DB99.7-DB99.8	Liver tissue	3.79E-03	1.24E+00	2.72E+00
Lung cancer	2C25	Lung tissue	2.29E-28	-5.62E-01	-1.35E+00
Lupus erythematosus	4A40	Whole blood	1.46E-05	4.28E-01	4.47E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	7.89E-01	9.78E-02	1.72E-01
Major depressive disorder	6A70-6A7Z	Whole blood	8.64E-02	2.18E-01	4.45E-01
Melanoma	2C30	Skin	2.96E-03	-1.12E+00	-9.55E-01
Multiple myeloma	2A83.1	Peripheral blood	3.72E-01	1.33E-01	7.30E-01
Multiple myeloma	2A83.1	Bone marrow	2.87E-02	-2.83E-01	-7.80E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	9.00E-02	1.81E-01	6.37E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.17E-02	1.24E-01	2.01E-01
Myelofibrosis	2A20.2	Whole blood	8.38E-01	-8.65E-02	-2.75E-01
Myocardial infarction	BA41-BA50	Peripheral blood	5.95E-04	1.79E+00	9.84E-01
Myopathy	8C70.6	Muscle tissue	3.14E-03	2.65E-01	1.10E+00
Neonatal sepsis	KA60	Whole blood	1.95E-16	6.27E-01	1.29E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	3.17E-12	-1.26E+00	-5.98E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.71E-01	-6.56E-02	-3.30E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.16E-01	-2.08E-01	-5.93E-01
Olive pollen allergy	CA08.00	Peripheral blood	7.93E-01	-1.56E-01	-2.98E-01
Oral cancer	2B6E	Oral tissue	1.72E-06	8.99E-01	1.12E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	7.89E-01	2.37E-02	2.18E-02
Osteoporosis	FB83.1	Bone marrow	9.61E-01	2.43E-01	2.96E-01
Ovarian cancer	2C73	Ovarian tissue	1.07E-03	3.59E+00	2.32E+00
Pancreatic cancer	2C10	Pancreas	1.81E-05	6.59E-01	1.75E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	2.19E-01	1.72E-01	5.16E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.40E-02	1.83E-01	2.94E-01
Pituitary cancer	2D12	Pituitary tissue	8.83E-01	-3.81E-01	-5.18E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	7.70E-02	-6.66E-01	-8.56E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.05E-02	8.15E-02	8.50E-01
Polycythemia vera	2A20.4	Whole blood	1.79E-06	3.88E-01	1.16E+00
Pompe disease	5C51.3	Biceps muscle	2.82E-01	-1.65E-01	-2.27E-01
Preterm birth	KA21.4Z	Myometrium	4.81E-01	-1.01E+00	-8.48E-01
Prostate cancer	2C82	Prostate	4.46E-01	-5.00E-02	-3.97E-02
Psoriasis	EA90	Skin	7.86E-02	1.05E-01	2.02E-01
Rectal cancer	2B92	Rectal colon tissue	4.06E-03	-9.04E-01	-2.26E+00
Renal cancer	2C90-2C91	Kidney	2.36E-03	3.80E-01	6.29E-01
Retinoblastoma	2D02.2	Uvea	8.66E-04	6.83E-01	2.70E+00
Rheumatoid arthritis	FA20	Synovial tissue	7.25E-01	-4.31E-02	-5.74E-02
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.31E-02	4.23E-02	3.47E-01
Schizophrenia	6A20	Prefrontal cortex	3.26E-01	1.33E-01	1.12E-01
Schizophrenia	6A20	Superior temporal cortex	2.34E-01	4.46E-02	4.03E-01
Scleroderma	4A42.Z	Whole blood	2.48E-01	1.88E-01	3.76E-01
Seizure	8A60-8A6Z	Whole blood	2.73E-02	-3.80E-01	-6.89E-01
Sensitive skin	EK0Z	Skin	2.13E-02	2.40E-01	9.13E-01
Sepsis with septic shock	1G41	Whole blood	5.73E-12	2.65E-01	6.23E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.24E-02	-3.26E-01	-7.78E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	5.55E-03	4.44E-01	1.35E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	3.37E-01	1.03E-02	3.76E-02
Sjogren's syndrome	4A43.2	Salivary gland tissue	5.62E-02	4.69E-01	1.62E+00
Skin cancer	2C30-2C3Z	Skin	2.54E-99	-2.57E+00	-4.16E+00
Thrombocythemia	3B63	Whole blood	1.94E-03	5.49E-01	1.74E+00
Thrombocytopenia	3B64	Whole blood	5.27E-02	8.16E-01	5.49E-01
Thyroid cancer	2D10	Thyroid	1.39E-12	4.87E-01	1.04E+00
Tibial muscular dystrophy	8C75	Muscle tissue	1.18E-07	6.15E-01	4.12E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.28E-02	1.04E+00	6.58E+00
Type 2 diabetes	5A11	Liver tissue	3.77E-01	3.23E-01	7.35E-01
Ureter cancer	2C92	Urothelium	5.77E-01	1.18E-02	8.93E-02
Uterine cancer	2C78	Endometrium tissue	2.10E-03	-3.85E-01	-2.74E-01
Vitiligo	ED63.0	Skin	3.51E-02	1.75E-01	6.04E-01