Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE08Z3W)

• DME Name: Cytosolic phospholipase A2 (PLA2G4A) DME Info
• Gene Name: PLA2G4A

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.20E-03	9.91E-02	1.15E-01
Alopecia	ED70	Skin from scalp	1.18E-03	-2.21E-01	-6.08E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.07E-01	1.06E-01	1.92E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	3.91E-01	-1.06E-01	-4.28E-01
Aortic stenosis	BB70	Calcified aortic valve	4.75E-01	-6.61E-01	-3.35E-01
Apnea	7A40	Hyperplastic tonsil	6.27E-02	-4.31E-01	-3.83E-01
Arthropathy	FA00-FA5Z	Peripheral blood	1.35E-01	3.06E-01	8.84E-01
Asthma	CA23	Nasal and bronchial airway	1.07E-07	1.62E+00	1.06E+00
Atopic dermatitis	EA80	Skin	1.01E-04	-2.79E-01	-9.93E-01
Autism	6A02	Whole blood	4.99E-02	3.39E-01	4.83E-01
Autoimmune uveitis	9A96	Peripheral monocyte	3.54E-01	5.05E-01	7.89E-01
Autosomal dominant monocytopenia	4B04	Whole blood	2.27E-02	5.85E-01	1.51E+00
Bacterial infection of gingival	1C1H	Gingival tissue	6.13E-05	-2.13E-01	-4.92E-01
Batten disease	5C56.1	Whole blood	5.97E-01	-8.82E-02	-1.41E-01
Behcet's disease	4A62	Peripheral blood	1.75E-01	3.46E-01	4.41E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.18E-01	-3.20E-01	-5.34E-01
Bladder cancer	2C94	Bladder tissue	6.66E-25	-2.35E+00	-1.23E+01
Breast cancer	2C60-2C6Z	Breast tissue	2.16E-74	-2.17E+00	-1.82E+00
Cardioembolic stroke	8B11.20	Whole blood	6.24E-06	5.86E-01	1.20E+00
Cervical cancer	2C77	Cervical tissue	2.82E-01	-1.04E-01	-1.65E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	9.01E-01	1.90E-01	2.31E-01
Chronic hepatitis C	1E51.1	Whole blood	5.13E-01	-2.35E-01	-3.21E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.68E-01	-3.86E-01	-5.29E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	5.50E-01	7.52E-02	9.23E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	2.04E-02	5.49E-01	6.66E-01
Colon cancer	2B90	Colon tissue	3.81E-08	-7.11E-01	-1.11E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	7.73E-01	-3.74E-01	-5.76E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	8.47E-01	2.68E-02	1.67E-01
Endometriosis	GA10	Endometrium tissue	4.32E-06	-2.13E+00	-1.40E+00
Familial hypercholesterolemia	5C80.00	Peripheral blood	1.99E-01	-1.37E-01	-4.21E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.08E-15	2.50E+00	1.92E+00
Gastric cancer	2B72	Gastric tissue	1.96E-01	1.35E+00	1.09E+00
Glioblastopma	2A00.00	Nervous tissue	2.64E-62	1.14E+00	1.44E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	6.21E-01	3.07E-01	4.17E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	3.06E-02	2.41E+00	1.64E+00
Head and neck cancer	2D42	Head and neck tissue	6.98E-04	-6.61E-01	-6.88E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.65E-02	1.39E-01	3.67E-01
Huntington's disease	8A01.10	Whole blood	6.29E-01	-1.26E-01	-5.29E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	4.48E-02	7.59E-01	1.30E+00
Immunodeficiency	4A00-4A20	Peripheral blood	4.10E-01	1.31E-02	2.52E-01
Influenza	1E30	Whole blood	8.53E-01	1.03E-01	9.87E-02
Interstitial cystitis	GC00.3	Bladder tissue	2.58E-04	-1.10E+00	-3.62E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.23E-02	7.60E-01	9.43E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.63E-02	-1.70E-01	-3.37E-01
Ischemic stroke	8B11	Peripheral blood	3.82E-01	-5.49E-01	-5.26E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.91E-01	-5.09E-02	-1.08E-01
Lateral sclerosis	8B60.4	Skin	5.91E-01	-2.69E-01	-3.17E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	2.14E-01	4.19E-02	4.31E-02
Liver cancer	2C12.0	Liver tissue	2.71E-01	-2.05E-01	-2.99E-01
Liver failure	DB99.7-DB99.8	Liver tissue	3.72E-02	7.86E-01	9.91E-01
Lung cancer	2C25	Lung tissue	2.96E-22	5.91E-01	9.40E-01
Lupus erythematosus	4A40	Whole blood	1.65E-08	7.11E-01	7.30E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	7.21E-01	-2.26E-01	-3.86E-01
Major depressive disorder	6A70-6A7Z	Whole blood	3.37E-01	2.52E-03	4.27E-03
Melanoma	2C30	Skin	2.80E-01	-3.30E-01	-2.24E-01
Multiple myeloma	2A83.1	Peripheral blood	6.47E-01	-2.78E-03	-6.98E-03
Multiple myeloma	2A83.1	Bone marrow	1.04E-04	1.24E+00	2.47E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	9.67E-01	1.33E-01	4.75E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	5.70E-05	7.32E-01	7.16E-01
Myelofibrosis	2A20.2	Whole blood	1.19E-04	4.70E-01	1.31E+00
Myocardial infarction	BA41-BA50	Peripheral blood	3.02E-03	1.04E+00	1.04E+00
Myopathy	8C70.6	Muscle tissue	1.29E-03	1.10E+00	2.25E+00
Neonatal sepsis	KA60	Whole blood	7.97E-27	1.34E+00	2.32E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.02E-03	8.56E-01	1.14E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.01E-01	-2.54E-02	-1.36E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.61E-01	-3.80E-02	-6.51E-02
Olive pollen allergy	CA08.00	Peripheral blood	7.09E-01	-2.63E-01	-2.28E-01
Oral cancer	2B6E	Oral tissue	6.89E-01	1.66E-01	1.48E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	6.76E-01	1.76E-01	1.18E-01
Osteoporosis	FB83.1	Bone marrow	5.32E-01	-9.77E-01	-7.74E-01
Ovarian cancer	2C73	Ovarian tissue	5.30E-01	-3.47E-01	-2.55E-01
Pancreatic cancer	2C10	Pancreas	3.63E-02	4.42E-01	4.62E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	9.63E-01	1.79E-01	3.23E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.03E-06	1.80E+00	2.24E+00
Pituitary cancer	2D12	Pituitary tissue	9.07E-01	-5.36E-02	-6.10E-02
Pituitary gonadotrope tumour	2D12	Pituitary tissue	6.15E-01	-3.51E-01	-4.54E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	1.90E-01	4.59E-02	4.12E-01
Polycythemia vera	2A20.4	Whole blood	4.45E-05	3.95E-01	1.03E+00
Pompe disease	5C51.3	Biceps muscle	3.42E-02	-3.69E-01	-8.22E-01
Preterm birth	KA21.4Z	Myometrium	1.75E-01	4.28E-01	5.29E-01
Prostate cancer	2C82	Prostate	6.33E-01	-1.44E-01	-1.12E-01
Psoriasis	EA90	Skin	8.58E-05	-2.34E-01	-4.34E-01
Rectal cancer	2B92	Rectal colon tissue	2.27E-03	-1.27E+00	-2.53E+00
Renal cancer	2C90-2C91	Kidney	2.27E-01	-7.34E-01	-7.05E-01
Retinoblastoma	2D02.2	Uvea	1.46E-04	1.70E+00	3.04E+00
Rheumatoid arthritis	FA20	Synovial tissue	2.64E-01	3.22E-01	3.87E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.40E-01	-1.08E-01	-3.71E-01
Schizophrenia	6A20	Prefrontal cortex	2.44E-01	-3.35E-01	-3.66E-01
Schizophrenia	6A20	Superior temporal cortex	4.40E-01	5.75E-02	3.59E-01
Scleroderma	4A42.Z	Whole blood	1.20E-04	5.97E-01	1.96E+00
Seizure	8A60-8A6Z	Whole blood	8.03E-01	5.17E-01	5.84E-01
Sensitive skin	EK0Z	Skin	6.95E-01	7.82E-02	2.84E-01
Sepsis with septic shock	1G41	Whole blood	2.12E-49	1.14E+00	1.82E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	6.11E-01	-1.19E-01	-1.35E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.21E-03	1.42E+00	1.83E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	2.66E-01	-6.16E-01	-8.13E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	9.35E-01	5.79E-02	1.74E-01
Skin cancer	2C30-2C3Z	Skin	3.39E-08	-3.22E-01	-6.21E-01
Thrombocythemia	3B63	Whole blood	5.52E-01	1.01E-01	2.83E-01
Thrombocytopenia	3B64	Whole blood	2.07E-01	3.64E-01	8.76E-01
Thyroid cancer	2D10	Thyroid	8.21E-02	1.19E-01	2.12E-01
Tibial muscular dystrophy	8C75	Muscle tissue	2.00E-05	1.44E+00	2.27E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.58E-01	1.52E-01	3.41E-01
Type 2 diabetes	5A11	Liver tissue	4.19E-01	3.05E-01	9.04E-01
Ureter cancer	2C92	Urothelium	8.55E-01	1.99E-02	1.36E-01
Uterine cancer	2C78	Endometrium tissue	1.94E-01	-3.19E-01	-2.80E-01
Vitiligo	ED63.0	Skin	2.36E-02	2.01E-01	1.06E+00