Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE2ZWSM)

• DME Name: Aldehyde dehydrogenase 7 (ALDH7) DME Info
• Gene Name: ALDH3B1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.88E-06	-1.69E-01	-4.55E-01
Alopecia	ED70	Skin from scalp	3.10E-01	-4.66E-02	-1.71E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.52E-01	2.65E-02	1.72E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	4.37E-01	1.11E-01	5.35E-01
Aortic stenosis	BB70	Calcified aortic valve	4.88E-01	1.76E-01	3.19E-01
Apnea	7A40	Hyperplastic tonsil	3.76E-01	-6.72E-04	-1.98E-03
Arthropathy	FA00-FA5Z	Peripheral blood	5.31E-01	1.14E-01	4.34E-01
Asthma	CA23	Nasal and bronchial airway	9.65E-01	9.68E-02	1.06E-01
Atopic dermatitis	EA80	Skin	9.87E-01	-1.28E-02	-8.73E-02
Autism	6A02	Whole blood	8.17E-01	7.78E-02	3.58E-01
Autoimmune uveitis	9A96	Peripheral monocyte	3.55E-02	-5.04E-01	-1.29E+00
Autosomal dominant monocytopenia	4B04	Whole blood	9.15E-01	6.66E-02	1.85E-01
Bacterial infection of gingival	1C1H	Gingival tissue	5.63E-09	2.37E-01	1.04E+00
Batten disease	5C56.1	Whole blood	5.58E-01	-4.68E-02	-1.49E-01
Behcet's disease	4A62	Peripheral blood	5.55E-01	7.92E-02	2.52E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	4.03E-01	2.67E-02	1.25E-01
Bladder cancer	2C94	Bladder tissue	1.45E-02	2.69E-01	1.20E+00
Breast cancer	2C60-2C6Z	Breast tissue	8.87E-01	-5.09E-02	-1.55E-01
Cardioembolic stroke	8B11.20	Whole blood	1.52E-01	-6.24E-02	-2.34E-01
Cervical cancer	2C77	Cervical tissue	4.70E-01	1.25E-01	3.10E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.25E-01	1.70E-01	4.33E-01
Chronic hepatitis C	1E51.1	Whole blood	9.66E-01	-1.61E-01	-3.74E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.64E-01	3.51E-03	1.01E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	5.95E-01	7.55E-02	1.19E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	4.30E-02	-6.73E-01	-1.04E+00
Colon cancer	2B90	Colon tissue	3.67E-01	6.44E-03	2.14E-02
Coronary artery disease	BA80-BA8Z	Peripheral blood	9.08E-01	-7.62E-02	-1.67E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	2.74E-01	8.22E-02	4.92E-01
Endometriosis	GA10	Endometrium tissue	8.69E-02	1.14E-01	4.20E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.11E-01	-5.28E-02	-2.66E-01
Familial hypercholesterolemia	5C80.00	Whole blood	6.69E-05	4.07E-01	1.83E+00
Gastric cancer	2B72	Gastric tissue	9.08E-01	-1.44E-01	-4.36E-01
Glioblastopma	2A00.00	Nervous tissue	9.76E-02	2.08E-02	5.59E-02
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	8.01E-01	2.00E-02	1.42E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	3.21E-03	-8.00E-01	-1.48E+00
Head and neck cancer	2D42	Head and neck tissue	3.29E-13	-4.69E-01	-3.09E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	2.80E-01	-1.56E-01	-7.30E-01
Huntington's disease	8A01.10	Whole blood	2.74E-01	1.63E-01	2.58E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	8.55E-02	3.97E-01	1.05E+00
Immunodeficiency	4A00-4A20	Peripheral blood	6.21E-02	1.73E-01	1.52E+00
Influenza	1E30	Whole blood	2.39E-01	1.52E-01	3.47E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.98E-01	-1.99E-01	-9.33E-01
Intracranial aneurysm	8B01.0	Intracranial artery	2.01E-02	3.01E-01	1.22E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	5.95E-01	2.10E-02	8.50E-02
Ischemic stroke	8B11	Peripheral blood	6.19E-01	4.27E-02	1.97E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	5.93E-01	-2.03E-02	-4.56E-02
Lateral sclerosis	8B60.4	Skin	6.47E-01	4.12E-02	1.97E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	9.38E-02	8.58E-02	4.25E-01
Liver cancer	2C12.0	Liver tissue	5.18E-01	-1.40E-01	-4.70E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.20E-02	2.39E-01	1.07E+00
Lung cancer	2C25	Lung tissue	3.08E-72	-1.11E+00	-2.37E+00
Lupus erythematosus	4A40	Whole blood	2.01E-01	2.27E-02	4.34E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	2.50E-01	-5.27E-02	-2.50E-01
Major depressive disorder	6A70-6A7Z	Whole blood	4.50E-04	1.53E-01	5.70E-01
Melanoma	2C30	Skin	3.76E-01	6.09E-01	5.59E-01
Multiple myeloma	2A83.1	Peripheral blood	6.97E-01	2.35E-02	7.83E-02
Multiple myeloma	2A83.1	Bone marrow	2.15E-03	-2.28E-01	-1.68E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.85E-01	9.30E-02	4.61E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.73E-09	7.48E-01	2.08E+00
Myelofibrosis	2A20.2	Whole blood	7.22E-04	2.41E-01	9.68E-01
Myocardial infarction	BA41-BA50	Peripheral blood	1.61E-03	7.89E-01	8.66E-01
Myopathy	8C70.6	Muscle tissue	3.09E-01	-8.82E-02	-4.19E-01
Neonatal sepsis	KA60	Whole blood	9.98E-09	3.39E-01	7.76E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	8.41E-05	-9.17E-01	-2.33E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	3.83E-01	-2.91E-02	-2.73E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.90E-01	2.61E-01	1.09E+00
Olive pollen allergy	CA08.00	Peripheral blood	1.45E-01	2.55E-01	8.97E-01
Oral cancer	2B6E	Oral tissue	1.30E-06	-4.14E-01	-1.21E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.68E-01	1.16E-01	3.43E-01
Osteoporosis	FB83.1	Bone marrow	9.35E-02	3.79E-01	3.81E+00
Ovarian cancer	2C73	Ovarian tissue	5.24E-01	1.11E-01	1.43E-01
Pancreatic cancer	2C10	Pancreas	7.18E-04	5.84E-01	1.34E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	1.82E-01	-9.54E-02	-5.64E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	7.37E-04	3.95E-01	1.21E+00
Pituitary cancer	2D12	Pituitary tissue	3.88E-02	-2.99E-01	-1.27E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.71E-04	-4.06E-01	-2.90E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	8.83E-01	-2.72E-02	-1.31E-01
Polycythemia vera	2A20.4	Whole blood	1.13E-02	9.43E-02	3.76E-01
Pompe disease	5C51.3	Biceps muscle	4.61E-04	4.90E-01	1.68E+00
Preterm birth	KA21.4Z	Myometrium	4.35E-02	3.82E-01	2.15E+00
Prostate cancer	2C82	Prostate	7.61E-02	-1.87E-01	-3.85E-01
Psoriasis	EA90	Skin	2.09E-07	-1.53E-01	-5.00E-01
Rectal cancer	2B92	Rectal colon tissue	1.63E-01	-4.49E-02	-1.73E-01
Renal cancer	2C90-2C91	Kidney	9.32E-01	-7.66E-02	-1.39E-01
Retinoblastoma	2D02.2	Uvea	5.15E-03	4.09E-01	3.12E+00
Rheumatoid arthritis	FA20	Synovial tissue	3.30E-02	3.32E-01	8.74E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	7.38E-02	-1.42E-01	-3.93E-01
Schizophrenia	6A20	Prefrontal cortex	3.81E-02	1.83E-01	3.30E-01
Schizophrenia	6A20	Superior temporal cortex	2.78E-01	-4.31E-02	-3.75E-01
Scleroderma	4A42.Z	Whole blood	8.62E-02	-9.20E-02	-4.77E-01
Seizure	8A60-8A6Z	Whole blood	9.12E-01	-2.62E-02	-8.76E-02
Sensitive skin	EK0Z	Skin	2.66E-02	9.29E-02	8.19E-01
Sepsis with septic shock	1G41	Whole blood	3.79E-16	2.58E-01	6.94E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	8.52E-03	-2.41E-01	-1.58E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	2.51E-02	1.53E-01	1.09E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.20E-01	1.81E-02	3.95E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.02E-01	-6.26E-02	-2.29E-01
Skin cancer	2C30-2C3Z	Skin	1.04E-03	9.17E-02	2.30E-01
Thrombocythemia	3B63	Whole blood	6.75E-02	5.89E-03	2.39E-02
Thrombocytopenia	3B64	Whole blood	2.88E-01	3.14E-01	5.07E-01
Thyroid cancer	2D10	Thyroid	1.98E-61	7.23E-01	2.84E+00
Tibial muscular dystrophy	8C75	Muscle tissue	4.39E-02	2.08E-01	8.94E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	9.55E-04	2.85E-01	3.53E+00
Type 2 diabetes	5A11	Liver tissue	8.32E-01	2.53E-02	1.46E-01
Ureter cancer	2C92	Urothelium	7.22E-01	-6.52E-02	-4.01E-01
Uterine cancer	2C78	Endometrium tissue	7.19E-18	-4.30E-01	-9.99E-01
Vitiligo	ED63.0	Skin	4.05E-02	-2.92E-01	-1.10E+00