Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE3OALH)

• DME Name: Prostaglandin E synthase 2 (PTGES2) DME Info
• Gene Name: PTGES2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	4.81E-02	1.44E-01	5.76E-01
Alopecia	ED70	Skin from scalp	4.62E-02	-1.35E-01	-5.09E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.35E-07	-1.99E-01	-8.11E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.41E-01	1.40E-01	8.59E-01
Aortic stenosis	BB70	Calcified aortic valve	4.70E-01	8.28E-02	1.59E-01
Apnea	7A40	Hyperplastic tonsil	5.51E-01	-3.67E-02	-1.79E-01
Arthropathy	FA00-FA5Z	Peripheral blood	1.62E-01	-9.74E-02	-6.76E-01
Asthma	CA23	Nasal and bronchial airway	4.71E-01	4.89E-02	1.76E-01
Atopic dermatitis	EA80	Skin	6.01E-07	4.96E-01	1.20E+00
Autism	6A02	Whole blood	6.25E-03	-2.25E-01	-1.25E+00
Autoimmune uveitis	9A96	Peripheral monocyte	1.12E-02	-2.19E-01	-1.30E+00
Autosomal dominant monocytopenia	4B04	Whole blood	8.79E-01	4.37E-02	2.22E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.10E-04	2.34E-01	7.07E-01
Batten disease	5C56.1	Whole blood	6.16E-01	-1.26E-01	-6.79E-01
Behcet's disease	4A62	Peripheral blood	8.87E-01	-2.03E-02	-1.16E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	2.91E-02	-8.08E-02	-6.15E-01
Bladder cancer	2C94	Bladder tissue	2.26E-01	6.70E-02	2.92E-01
Breast cancer	2C60-2C6Z	Breast tissue	2.98E-11	1.54E-01	4.61E-01
Cardioembolic stroke	8B11.20	Whole blood	2.54E-02	-1.19E-01	-6.60E-01
Cervical cancer	2C77	Cervical tissue	7.08E-01	-2.79E-02	-6.49E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	3.93E-02	7.26E-02	4.62E-01
Chronic hepatitis C	1E51.1	Whole blood	5.43E-01	-2.69E-02	-2.46E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.46E-01	-2.84E-02	-8.28E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	6.90E-03	1.06E-01	3.04E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	2.17E-01	1.18E-01	7.78E-01
Colon cancer	2B90	Colon tissue	1.28E-01	-9.85E-03	-3.43E-02
Coronary artery disease	BA80-BA8Z	Peripheral blood	4.36E-01	-7.31E-02	-4.27E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.10E-01	-2.00E-01	-7.00E-01
Endometriosis	GA10	Endometrium tissue	6.34E-01	6.11E-02	1.46E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	4.19E-01	1.20E-01	7.93E-01
Familial hypercholesterolemia	5C80.00	Whole blood	7.93E-04	-2.37E-01	-1.03E+00
Gastric cancer	2B72	Gastric tissue	7.80E-01	-4.75E-02	-1.91E-01
Glioblastopma	2A00.00	Nervous tissue	2.62E-106	-6.75E-01	-1.56E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	6.25E-01	-2.18E-01	-4.84E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	6.99E-01	1.48E-01	3.69E-01
Head and neck cancer	2D42	Head and neck tissue	1.55E-03	1.01E-01	4.10E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	2.89E-01	-4.09E-02	-9.77E-02
Huntington's disease	8A01.10	Whole blood	3.12E-01	6.30E-02	3.78E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	6.81E-03	2.53E-01	2.97E+00
Immunodeficiency	4A00-4A20	Peripheral blood	1.02E-01	7.44E-02	8.96E-01
Influenza	1E30	Whole blood	3.37E-01	3.19E-01	1.79E+00
Interstitial cystitis	GC00.3	Bladder tissue	5.95E-01	9.83E-02	4.91E-01
Intracranial aneurysm	8B01.0	Intracranial artery	7.01E-01	-6.22E-02	-1.07E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.83E-01	-1.03E-02	-5.48E-02
Ischemic stroke	8B11	Peripheral blood	6.56E-02	-8.98E-02	-7.70E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	9.96E-03	-1.21E-01	-4.56E-01
Lateral sclerosis	8B60.4	Skin	1.61E-01	2.44E-01	2.28E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	3.99E-01	-1.09E-01	-3.05E-01
Liver cancer	2C12.0	Liver tissue	4.99E-04	-7.72E-02	-3.85E-01
Liver failure	DB99.7-DB99.8	Liver tissue	5.06E-02	-3.42E-01	-1.32E+00
Lung cancer	2C25	Lung tissue	6.19E-19	2.25E-01	9.09E-01
Lupus erythematosus	4A40	Whole blood	2.51E-02	-8.27E-02	-1.99E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	6.40E-01	3.89E-02	2.91E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.47E-02	8.28E-02	4.48E-01
Melanoma	2C30	Skin	6.23E-01	8.00E-02	1.30E-01
Multiple myeloma	2A83.1	Peripheral blood	1.43E-01	-2.51E-01	-9.84E-01
Multiple myeloma	2A83.1	Bone marrow	2.61E-02	2.10E-01	7.44E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	6.59E-01	3.96E-02	3.50E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.24E-01	5.88E-02	1.83E-01
Myelofibrosis	2A20.2	Whole blood	1.77E-01	-5.48E-02	-4.43E-01
Myocardial infarction	BA41-BA50	Peripheral blood	5.30E-01	1.27E-02	4.51E-02
Myopathy	8C70.6	Muscle tissue	8.27E-03	-1.46E-01	-1.35E+00
Neonatal sepsis	KA60	Whole blood	7.07E-02	-1.22E-01	-4.01E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.92E-07	-5.69E-01	-3.38E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.85E-01	-1.37E-01	-6.51E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	7.95E-01	2.82E-02	1.61E-01
Olive pollen allergy	CA08.00	Peripheral blood	2.80E-03	5.28E-01	3.37E+00
Oral cancer	2B6E	Oral tissue	5.89E-07	-4.61E-01	-1.37E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	4.15E-01	-4.52E-01	-1.52E+00
Osteoporosis	FB83.1	Bone marrow	1.46E-02	2.55E-01	1.87E+00
Ovarian cancer	2C73	Ovarian tissue	3.39E-02	2.71E-01	8.17E-01
Pancreatic cancer	2C10	Pancreas	3.94E-01	-5.81E-02	-1.27E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	1.43E-01	-2.02E-01	-1.07E+00
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	3.02E-01	8.01E-02	5.53E-01
Pituitary cancer	2D12	Pituitary tissue	2.96E-04	4.00E-01	2.04E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	6.01E-03	4.55E-01	2.60E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.40E-01	-6.02E-02	-2.37E-01
Polycythemia vera	2A20.4	Whole blood	8.46E-06	-1.17E-01	-9.02E-01
Pompe disease	5C51.3	Biceps muscle	2.32E-01	7.23E-02	3.26E-01
Preterm birth	KA21.4Z	Myometrium	7.01E-01	-7.10E-02	-4.00E-01
Prostate cancer	2C82	Prostate	7.71E-01	-1.13E-01	-1.91E-01
Psoriasis	EA90	Skin	9.61E-02	3.82E-02	9.50E-02
Rectal cancer	2B92	Rectal colon tissue	6.96E-01	7.76E-02	1.17E+00
Renal cancer	2C90-2C91	Kidney	3.43E-03	-4.88E-01	-1.22E+00
Retinoblastoma	2D02.2	Uvea	2.88E-06	-4.73E-01	-2.65E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.04E-01	-4.87E-01	-8.97E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.98E-01	-5.20E-04	-3.51E-03
Schizophrenia	6A20	Prefrontal cortex	2.51E-03	-1.91E-01	-5.63E-01
Schizophrenia	6A20	Superior temporal cortex	2.07E-01	-5.40E-02	-3.50E-01
Scleroderma	4A42.Z	Whole blood	2.73E-01	4.28E-02	3.40E-01
Seizure	8A60-8A6Z	Whole blood	7.92E-01	-9.03E-02	-6.70E-01
Sensitive skin	EK0Z	Skin	3.61E-01	3.18E-02	1.78E-01
Sepsis with septic shock	1G41	Whole blood	6.06E-08	-1.93E-01	-6.98E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.28E-01	5.20E-02	4.10E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.35E-01	2.81E-01	5.86E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	5.57E-01	2.39E-02	1.66E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.27E-01	6.54E-03	2.04E-02
Skin cancer	2C30-2C3Z	Skin	1.36E-02	1.22E-01	2.70E-01
Thrombocythemia	3B63	Whole blood	6.58E-07	-1.68E-01	-1.34E+00
Thrombocytopenia	3B64	Whole blood	5.12E-01	5.69E-01	5.31E-01
Thyroid cancer	2D10	Thyroid	2.35E-01	1.40E-02	4.66E-02
Tibial muscular dystrophy	8C75	Muscle tissue	1.22E-02	-2.62E-01	-7.69E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	4.10E-02	-3.59E-01	-2.37E+00
Type 2 diabetes	5A11	Liver tissue	2.43E-01	-3.08E-02	-1.82E-01
Ureter cancer	2C92	Urothelium	6.67E-01	-8.14E-02	-2.51E-01
Uterine cancer	2C78	Endometrium tissue	1.11E-04	-7.33E-02	-1.25E-01
Vitiligo	ED63.0	Skin	4.72E-01	4.94E-02	2.36E-01