Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE8451N)

• DME Name: Glucosamine-6-phosphate deaminase 1 (GNPDA1) DME Info
• Gene Name: GNPDA1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	3.94E-07	-2.75E-01	-5.35E-01
Alopecia	ED70	Skin from scalp	4.01E-02	6.31E-02	2.51E-01
Alzheimer's disease	8A20	Entorhinal cortex	7.76E-02	-3.84E-02	-2.27E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.05E-01	9.89E-02	2.79E-01
Aortic stenosis	BB70	Calcified aortic valve	9.86E-01	-2.19E-01	-1.77E-01
Apnea	7A40	Hyperplastic tonsil	7.51E-02	-1.89E-01	-5.17E-01
Arthropathy	FA00-FA5Z	Peripheral blood	6.16E-02	-1.59E-01	-7.23E-01
Asthma	CA23	Nasal and bronchial airway	7.56E-05	2.20E-01	2.08E-01
Atopic dermatitis	EA80	Skin	8.06E-01	3.60E-02	1.54E-01
Autism	6A02	Whole blood	6.00E-01	-7.28E-02	-3.44E-01
Autoimmune uveitis	9A96	Peripheral monocyte	2.16E-01	6.45E-01	1.59E+00
Autosomal dominant monocytopenia	4B04	Whole blood	3.77E-02	1.83E+00	1.39E+00
Bacterial infection of gingival	1C1H	Gingival tissue	2.30E-01	4.80E-02	1.87E-01
Batten disease	5C56.1	Whole blood	9.57E-02	6.89E-02	5.07E-01
Behcet's disease	4A62	Peripheral blood	6.78E-01	-1.65E-02	-7.42E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	9.25E-01	-5.86E-03	-2.41E-02
Bladder cancer	2C94	Bladder tissue	5.28E-04	-8.83E-01	-2.76E+00
Breast cancer	2C60-2C6Z	Breast tissue	7.74E-19	1.79E-01	3.86E-01
Cardioembolic stroke	8B11.20	Whole blood	2.71E-09	5.33E-01	1.95E+00
Cervical cancer	2C77	Cervical tissue	7.80E-02	1.84E-01	5.55E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	9.68E-01	-3.66E-02	-6.97E-02
Chronic hepatitis C	1E51.1	Whole blood	7.79E-01	-6.95E-02	-1.44E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.85E-01	-3.91E-02	-1.14E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	3.53E-01	-2.80E-02	-6.45E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	9.15E-01	5.66E-02	2.30E-01
Colon cancer	2B90	Colon tissue	1.48E-70	8.61E-01	2.20E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.00E-01	1.08E-01	1.30E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	3.46E-01	1.93E-01	3.55E-01
Endometriosis	GA10	Endometrium tissue	5.87E-01	2.52E-02	4.37E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.52E-02	1.06E-01	6.45E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.49E-07	7.30E-01	1.92E+00
Gastric cancer	2B72	Gastric tissue	1.21E-02	7.65E-01	4.83E+00
Glioblastopma	2A00.00	Nervous tissue	1.21E-18	1.30E-01	4.31E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	7.31E-01	-1.83E-01	-4.08E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.13E-01	7.96E-01	9.46E-01
Head and neck cancer	2D42	Head and neck tissue	3.50E-22	4.01E-01	1.46E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	6.66E-01	-6.62E-02	-1.87E-01
Huntington's disease	8A01.10	Whole blood	4.02E-01	-2.06E-01	-6.53E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	9.02E-01	1.34E-01	2.85E-01
Immunodeficiency	4A00-4A20	Peripheral blood	2.79E-01	1.63E-01	1.20E+00
Influenza	1E30	Whole blood	5.70E-02	-8.64E-01	-2.20E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.93E-04	-6.52E-01	-2.99E+00
Intracranial aneurysm	8B01.0	Intracranial artery	5.35E-03	8.99E-01	2.26E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.20E-02	-2.34E-02	-1.05E-01
Ischemic stroke	8B11	Peripheral blood	1.30E-01	-1.56E-01	-5.14E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.78E-03	1.32E-01	4.94E-01
Lateral sclerosis	8B60.4	Skin	7.68E-01	-4.63E-03	-5.38E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	6.59E-01	2.75E-02	3.10E-02
Liver cancer	2C12.0	Liver tissue	7.50E-10	4.20E-01	9.74E-01
Liver failure	DB99.7-DB99.8	Liver tissue	7.48E-07	1.40E+00	4.15E+00
Lung cancer	2C25	Lung tissue	2.36E-18	2.92E-01	8.49E-01
Lupus erythematosus	4A40	Whole blood	1.22E-04	1.97E-01	4.14E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	9.83E-01	-5.42E-02	-2.41E-01
Major depressive disorder	6A70-6A7Z	Whole blood	6.98E-01	4.12E-04	1.37E-03
Melanoma	2C30	Skin	2.91E-03	6.10E-01	8.86E-01
Multiple myeloma	2A83.1	Peripheral blood	7.80E-01	2.71E-01	5.35E-01
Multiple myeloma	2A83.1	Bone marrow	2.70E-01	2.83E-01	6.15E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.20E-01	-1.79E-01	-4.95E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.01E-09	1.68E+00	1.95E+00
Myelofibrosis	2A20.2	Whole blood	5.82E-01	1.31E-02	7.50E-02
Myocardial infarction	BA41-BA50	Peripheral blood	2.92E-03	-1.98E-01	-3.16E-01
Myopathy	8C70.6	Muscle tissue	1.61E-02	3.28E-01	1.24E+00
Neonatal sepsis	KA60	Whole blood	2.88E-06	2.87E-01	8.07E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	6.63E-04	4.68E-01	1.35E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.59E-01	6.01E-02	2.16E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.47E-01	-1.94E-01	-3.43E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.40E-01	6.47E-01	1.19E+00
Oral cancer	2B6E	Oral tissue	2.45E-05	4.45E-01	9.93E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.69E-01	1.42E-01	5.62E-01
Osteoporosis	FB83.1	Bone marrow	2.91E-01	-1.59E-01	-3.01E-01
Ovarian cancer	2C73	Ovarian tissue	4.12E-01	8.41E-03	3.69E-02
Pancreatic cancer	2C10	Pancreas	6.44E-04	3.33E-01	7.87E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	1.55E-01	1.19E-01	3.17E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	4.26E-04	2.58E-01	1.04E+00
Pituitary cancer	2D12	Pituitary tissue	1.22E-01	8.99E-02	2.39E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	9.67E-01	-5.09E-02	-1.77E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.73E-01	1.46E-02	1.25E-01
Polycythemia vera	2A20.4	Whole blood	5.96E-01	-4.48E-03	-2.90E-02
Pompe disease	5C51.3	Biceps muscle	1.75E-07	1.24E+00	5.46E+00
Preterm birth	KA21.4Z	Myometrium	8.03E-01	-3.79E-02	-3.06E-01
Prostate cancer	2C82	Prostate	4.98E-04	-3.84E-01	-8.21E-01
Psoriasis	EA90	Skin	5.64E-05	1.50E-01	5.92E-01
Rectal cancer	2B92	Rectal colon tissue	6.90E-06	4.05E-01	3.61E+00
Renal cancer	2C90-2C91	Kidney	7.77E-01	7.60E-02	1.80E-01
Retinoblastoma	2D02.2	Uvea	2.94E-14	1.92E+00	7.87E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.15E-01	2.67E-01	3.82E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	9.35E-02	9.35E-02	4.40E-01
Schizophrenia	6A20	Prefrontal cortex	2.74E-01	-3.39E-02	-1.60E-01
Schizophrenia	6A20	Superior temporal cortex	6.73E-01	-6.18E-02	-3.75E-01
Scleroderma	4A42.Z	Whole blood	2.15E-01	-8.62E-02	-7.63E-01
Seizure	8A60-8A6Z	Whole blood	7.36E-02	-8.69E-02	-3.57E-01
Sensitive skin	EK0Z	Skin	7.70E-02	1.04E-01	1.44E+00
Sepsis with septic shock	1G41	Whole blood	8.85E-06	1.27E-01	4.08E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	8.92E-01	7.18E-02	2.60E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	3.29E-03	-5.91E-01	-6.30E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.45E-01	-1.13E-02	-2.22E-02
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.87E-03	8.29E-01	4.02E+00
Skin cancer	2C30-2C3Z	Skin	4.30E-55	7.92E-01	2.74E+00
Thrombocythemia	3B63	Whole blood	2.67E-01	3.81E-02	2.17E-01
Thrombocytopenia	3B64	Whole blood	3.60E-01	4.42E-01	1.36E+00
Thyroid cancer	2D10	Thyroid	5.18E-34	4.79E-01	2.07E+00
Tibial muscular dystrophy	8C75	Muscle tissue	8.48E-01	1.23E-03	7.08E-03
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.49E-01	-2.68E-01	-2.55E+00
Type 2 diabetes	5A11	Liver tissue	4.71E-01	3.46E-01	1.65E+00
Ureter cancer	2C92	Urothelium	2.27E-01	2.69E-02	1.17E-01
Uterine cancer	2C78	Endometrium tissue	6.88E-11	3.30E-01	7.70E-01
Vitiligo	ED63.0	Skin	3.72E-01	-5.82E-02	-2.06E-01