Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE8LBNO)

• DME Name: Poly [ADP-ribose] polymerase 3 (PARP3) DME Info
• Gene Name: PARP3

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.27E-09	2.28E-01	7.85E-01
Alopecia	ED70	Skin from scalp	2.82E-02	2.21E-01	5.84E-01
Alzheimer's disease	8A20	Entorhinal cortex	5.35E-01	-1.09E-02	-5.65E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.82E-01	-5.85E-02	-2.75E-01
Aortic stenosis	BB70	Calcified aortic valve	9.53E-01	-1.64E-02	-4.55E-02
Apnea	7A40	Hyperplastic tonsil	3.14E-01	2.74E-01	1.33E+00
Arthropathy	FA00-FA5Z	Peripheral blood	9.54E-01	-2.32E-04	-1.69E-03
Asthma	CA23	Nasal and bronchial airway	5.22E-02	1.67E-02	3.34E-02
Atopic dermatitis	EA80	Skin	6.82E-03	1.05E-01	5.81E-01
Autism	6A02	Whole blood	5.26E-02	-1.29E-01	-5.50E-01
Autoimmune uveitis	9A96	Peripheral monocyte	5.48E-01	4.17E-03	2.68E-02
Autosomal dominant monocytopenia	4B04	Whole blood	3.08E-02	4.14E-01	1.46E+00
Bacterial infection of gingival	1C1H	Gingival tissue	5.73E-05	2.34E-01	7.70E-01
Batten disease	5C56.1	Whole blood	3.32E-01	9.71E-02	5.94E-01
Behcet's disease	4A62	Peripheral blood	8.32E-01	1.30E-02	8.38E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.51E-01	3.41E-02	1.80E-01
Bladder cancer	2C94	Bladder tissue	5.90E-03	-3.23E-01	-1.40E+00
Breast cancer	2C60-2C6Z	Breast tissue	1.84E-26	-2.95E-01	-7.68E-01
Cardioembolic stroke	8B11.20	Whole blood	5.49E-01	-2.84E-02	-1.44E-01
Cervical cancer	2C77	Cervical tissue	7.22E-01	1.19E-02	3.87E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	3.47E-02	1.34E-01	5.80E-01
Chronic hepatitis C	1E51.1	Whole blood	4.75E-01	-3.19E-02	-1.34E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.34E-01	-1.22E-01	-4.82E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.12E-02	-1.56E-01	-3.78E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	3.79E-01	8.19E-02	3.63E-01
Colon cancer	2B90	Colon tissue	6.72E-01	-3.19E-02	-1.05E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.74E-01	1.92E-01	1.25E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	9.62E-01	-5.59E-02	-2.17E-01
Endometriosis	GA10	Endometrium tissue	2.00E-01	1.14E-01	4.06E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.77E-01	-1.36E-02	-8.35E-02
Familial hypercholesterolemia	5C80.00	Whole blood	5.65E-03	-3.29E-01	-1.58E+00
Gastric cancer	2B72	Gastric tissue	5.38E-01	-1.16E-01	-1.85E-01
Glioblastopma	2A00.00	Nervous tissue	3.02E-21	1.50E-01	4.91E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	4.08E-03	2.15E-01	5.57E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.13E-01	-5.19E-02	-1.59E-01
Head and neck cancer	2D42	Head and neck tissue	1.31E-05	-3.09E-01	-5.05E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	5.67E-01	1.40E-03	9.25E-03
Huntington's disease	8A01.10	Whole blood	6.97E-02	8.50E-02	2.66E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	6.35E-03	3.15E-01	1.50E+00
Immunodeficiency	4A00-4A20	Peripheral blood	2.43E-03	1.93E-01	1.39E+00
Influenza	1E30	Whole blood	9.52E-01	2.30E-02	2.91E-01
Interstitial cystitis	GC00.3	Bladder tissue	1.38E-01	-4.35E-01	-2.28E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.14E-03	4.22E-01	1.21E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.67E-01	-2.09E-02	-7.35E-02
Ischemic stroke	8B11	Peripheral blood	4.06E-01	-1.16E-02	-7.63E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.88E-03	-8.21E-02	-3.46E-01
Lateral sclerosis	8B60.4	Skin	8.38E-01	1.40E-02	8.84E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	2.69E-01	-8.15E-02	-3.50E-01
Liver cancer	2C12.0	Liver tissue	1.83E-01	-1.84E-01	-5.09E-01
Liver failure	DB99.7-DB99.8	Liver tissue	5.41E-01	8.87E-03	1.54E-02
Lung cancer	2C25	Lung tissue	8.11E-10	-1.86E-01	-5.70E-01
Lupus erythematosus	4A40	Whole blood	1.14E-01	-2.98E-02	-6.93E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	5.23E-01	6.21E-02	3.40E-01
Major depressive disorder	6A70-6A7Z	Whole blood	6.48E-01	-2.40E-03	-9.39E-03
Melanoma	2C30	Skin	6.24E-01	7.05E-02	1.04E-01
Multiple myeloma	2A83.1	Peripheral blood	7.91E-01	-1.18E-01	-5.16E-01
Multiple myeloma	2A83.1	Bone marrow	8.00E-02	1.47E-01	9.81E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	9.83E-01	-5.80E-02	-1.80E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	3.76E-02	6.35E-02	1.83E-01
Myelofibrosis	2A20.2	Whole blood	6.36E-01	7.41E-02	6.46E-01
Myocardial infarction	BA41-BA50	Peripheral blood	4.96E-01	5.21E-02	1.50E-01
Myopathy	8C70.6	Muscle tissue	5.07E-03	2.41E-01	1.76E+00
Neonatal sepsis	KA60	Whole blood	7.51E-01	-3.14E-02	-1.13E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.08E-02	-3.62E-01	-1.28E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	6.48E-01	-5.35E-02	-2.57E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.64E-01	4.96E-02	6.26E-01
Olive pollen allergy	CA08.00	Peripheral blood	2.50E-01	7.94E-02	4.31E-01
Oral cancer	2B6E	Oral tissue	8.33E-01	-9.58E-04	-3.88E-03
Osteoarthritis	FA00-FA0Z	Synovial tissue	7.42E-01	2.53E-01	3.00E-01
Osteoporosis	FB83.1	Bone marrow	7.43E-01	-8.42E-04	-4.75E-03
Ovarian cancer	2C73	Ovarian tissue	3.23E-04	7.93E-01	2.09E+00
Pancreatic cancer	2C10	Pancreas	4.86E-06	6.21E-01	1.72E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	4.19E-01	-1.05E-02	-6.09E-02
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	7.25E-01	-1.81E-02	-8.38E-02
Pituitary cancer	2D12	Pituitary tissue	2.30E-01	9.15E-02	4.04E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.74E-01	-5.41E-02	-3.06E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.34E-01	7.89E-02	3.49E-01
Polycythemia vera	2A20.4	Whole blood	7.61E-07	1.44E-01	1.43E+00
Pompe disease	5C51.3	Biceps muscle	8.60E-01	8.60E-02	2.83E-01
Preterm birth	KA21.4Z	Myometrium	4.34E-01	2.26E-02	5.86E-02
Prostate cancer	2C82	Prostate	7.90E-05	-3.87E-01	-9.68E-01
Psoriasis	EA90	Skin	5.31E-02	4.14E-02	1.33E-01
Rectal cancer	2B92	Rectal colon tissue	3.62E-01	-1.28E-01	-3.35E-01
Renal cancer	2C90-2C91	Kidney	2.44E-01	-2.12E-01	-6.15E-01
Retinoblastoma	2D02.2	Uvea	9.29E-06	5.42E-01	8.34E+00
Rheumatoid arthritis	FA20	Synovial tissue	7.90E-05	8.29E-01	2.86E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	8.40E-01	8.08E-03	4.53E-02
Schizophrenia	6A20	Prefrontal cortex	2.93E-01	4.08E-02	1.46E-01
Schizophrenia	6A20	Superior temporal cortex	7.40E-02	-8.71E-02	-6.09E-01
Scleroderma	4A42.Z	Whole blood	3.67E-01	6.87E-02	3.19E-01
Seizure	8A60-8A6Z	Whole blood	2.25E-01	1.16E-02	6.52E-02
Sensitive skin	EK0Z	Skin	6.14E-01	-5.72E-03	-1.01E-01
Sepsis with septic shock	1G41	Whole blood	4.76E-05	-2.98E-02	-1.01E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.10E-01	1.16E-01	6.01E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	8.31E-01	8.60E-02	3.83E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	4.56E-01	3.23E-01	8.80E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.29E-02	2.77E-01	1.59E+00
Skin cancer	2C30-2C3Z	Skin	1.29E-10	2.47E-01	7.75E-01
Thrombocythemia	3B63	Whole blood	1.41E-03	8.36E-02	8.06E-01
Thrombocytopenia	3B64	Whole blood	4.93E-01	3.41E-01	3.92E-01
Thyroid cancer	2D10	Thyroid	4.35E-02	-1.21E-01	-3.42E-01
Tibial muscular dystrophy	8C75	Muscle tissue	4.46E-02	-1.59E-01	-4.64E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	9.08E-01	1.14E-01	4.28E-01
Type 2 diabetes	5A11	Liver tissue	2.30E-01	-1.84E-01	-8.02E-01
Ureter cancer	2C92	Urothelium	9.95E-01	-3.85E-02	-1.77E-01
Uterine cancer	2C78	Endometrium tissue	2.59E-02	-1.10E-01	-3.84E-01
Vitiligo	ED63.0	Skin	1.47E-01	-9.16E-02	-5.41E-01