Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEBMFZ8)

• DME Name: Estradiol 17-beta-dehydrogenase 2 (HSD17B2) DME Info
• Gene Name: HSD17B2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	6.87E-01	2.71E-02	1.69E-01
Alopecia	ED70	Skin from scalp	2.42E-02	-1.62E-01	-3.46E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.98E-02	-3.85E-02	-2.11E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.89E-01	-8.64E-02	-9.43E-01
Aortic stenosis	BB70	Calcified aortic valve	8.66E-01	-2.11E-01	-5.30E-01
Apnea	7A40	Hyperplastic tonsil	8.27E-03	1.80E+00	2.80E+00
Arthropathy	FA00-FA5Z	Peripheral blood	8.78E-01	-1.95E-02	-1.28E-01
Asthma	CA23	Nasal and bronchial airway	1.25E-03	9.19E-01	5.69E-01
Atopic dermatitis	EA80	Skin	1.18E-02	6.14E-01	6.32E-01
Autism	6A02	Whole blood	9.27E-02	-7.97E-02	-5.41E-01
Autoimmune uveitis	9A96	Peripheral monocyte	7.60E-02	-1.28E-01	-1.72E+00
Autosomal dominant monocytopenia	4B04	Whole blood	6.29E-02	1.47E-01	7.00E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.50E-02	1.00E-01	3.51E-01
Batten disease	5C56.1	Whole blood	7.89E-01	4.39E-03	4.73E-02
Behcet's disease	4A62	Peripheral blood	2.82E-01	1.71E-02	1.28E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	8.75E-01	-5.67E-02	-4.40E-01
Bladder cancer	2C94	Bladder tissue	4.10E-05	-3.48E+00	-3.65E+00
Breast cancer	2C60-2C6Z	Breast tissue	4.54E-19	-1.35E+00	-1.11E+00
Cardioembolic stroke	8B11.20	Whole blood	4.54E-01	3.42E-02	2.46E-01
Cervical cancer	2C77	Cervical tissue	1.18E-01	6.24E-01	5.68E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.35E-01	-2.83E-02	-1.59E-01
Chronic hepatitis C	1E51.1	Whole blood	2.24E-01	4.06E-02	2.38E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	8.26E-01	1.47E-02	3.39E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	4.83E-02	-2.15E-01	-2.50E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.34E-01	1.94E-01	2.60E-01
Colon cancer	2B90	Colon tissue	2.65E-173	-4.12E+00	-5.57E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.13E-01	-1.00E-01	-4.09E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	3.77E-01	-5.22E-03	-3.25E-02
Endometriosis	GA10	Endometrium tissue	1.12E-02	-4.03E+00	-1.74E+00
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.82E-01	2.38E-02	1.55E-01
Familial hypercholesterolemia	5C80.00	Whole blood	7.65E-01	-4.12E-03	-2.87E-02
Gastric cancer	2B72	Gastric tissue	4.55E-01	8.52E-01	3.77E-01
Glioblastopma	2A00.00	Nervous tissue	1.40E-02	-7.96E-02	-2.79E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	5.25E-01	9.04E-02	5.84E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	8.15E-04	-5.38E-01	-1.67E+00
Head and neck cancer	2D42	Head and neck tissue	3.41E-10	7.41E-01	8.92E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.13E-01	-6.50E-02	-1.80E-01
Huntington's disease	8A01.10	Whole blood	5.38E-01	1.82E-02	1.31E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	5.36E-01	-4.09E-02	-8.12E-02
Immunodeficiency	4A00-4A20	Peripheral blood	8.74E-01	5.74E-02	4.34E-01
Influenza	1E30	Whole blood	1.41E-01	4.23E-01	1.67E+00
Interstitial cystitis	GC00.3	Bladder tissue	5.89E-01	-5.43E-02	-1.28E-01
Intracranial aneurysm	8B01.0	Intracranial artery	1.39E-03	2.55E-01	1.49E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.08E-01	-5.08E-01	-7.96E-01
Ischemic stroke	8B11	Peripheral blood	8.57E-03	1.48E-01	8.57E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.27E-01	-5.97E-02	-2.41E-01
Lateral sclerosis	8B60.4	Skin	6.85E-01	-1.07E-01	-2.96E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	2.73E-02	1.26E-01	1.08E+00
Liver cancer	2C12.0	Liver tissue	4.88E-27	-1.16E+00	-2.19E+00
Liver failure	DB99.7-DB99.8	Liver tissue	1.26E-04	-2.11E+00	-4.34E+00
Lung cancer	2C25	Lung tissue	6.88E-01	-4.96E-01	-8.16E-01
Lupus erythematosus	4A40	Whole blood	8.63E-01	-5.08E-02	-1.81E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	4.90E-01	-8.34E-04	-6.49E-03
Major depressive disorder	6A70-6A7Z	Whole blood	7.93E-01	8.41E-03	3.96E-02
Melanoma	2C30	Skin	7.04E-04	-2.81E+00	-1.24E+00
Multiple myeloma	2A83.1	Peripheral blood	5.45E-01	2.98E-02	2.20E-01
Multiple myeloma	2A83.1	Bone marrow	3.03E-02	-1.54E-01	-8.19E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	9.57E-01	-3.67E-03	-2.48E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	4.52E-02	4.39E-02	2.70E-01
Myelofibrosis	2A20.2	Whole blood	8.36E-02	-9.42E-02	-7.71E-01
Myocardial infarction	BA41-BA50	Peripheral blood	9.18E-01	-9.28E-03	-2.16E-02
Myopathy	8C70.6	Muscle tissue	8.73E-01	-5.65E-02	-2.81E-01
Neonatal sepsis	KA60	Whole blood	9.27E-01	5.03E-03	2.57E-02
Neuroectodermal tumour	2A00.11	Brain stem tissue	6.81E-01	-3.05E-01	-9.32E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.20E-01	-2.47E-01	-3.79E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	8.36E-02	-2.62E-01	-4.31E-01
Olive pollen allergy	CA08.00	Peripheral blood	5.84E-01	6.39E-02	3.88E-01
Oral cancer	2B6E	Oral tissue	5.06E-04	8.68E-01	9.23E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	9.31E-01	1.14E-01	5.05E-01
Osteoporosis	FB83.1	Bone marrow	4.86E-02	1.49E-01	1.28E+00
Ovarian cancer	2C73	Ovarian tissue	6.23E-01	8.97E-02	7.82E-02
Pancreatic cancer	2C10	Pancreas	9.35E-03	5.81E-01	3.44E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	2.71E-01	-5.63E-04	-2.81E-03
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	7.10E-01	3.83E-03	2.34E-02
Pituitary cancer	2D12	Pituitary tissue	3.22E-01	-1.54E-01	-3.31E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.55E-01	-1.29E-01	-2.65E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.12E-01	6.30E-02	3.79E-01
Polycythemia vera	2A20.4	Whole blood	5.94E-01	-1.47E-03	-9.30E-03
Pompe disease	5C51.3	Biceps muscle	1.32E-01	5.84E-02	5.68E-01
Preterm birth	KA21.4Z	Myometrium	8.91E-01	-1.08E-02	-7.14E-03
Prostate cancer	2C82	Prostate	4.21E-02	-3.86E-01	-3.06E-01
Psoriasis	EA90	Skin	1.05E-10	1.47E+00	1.30E+00
Rectal cancer	2B92	Rectal colon tissue	8.17E-10	-3.03E+00	-7.52E+00
Renal cancer	2C90-2C91	Kidney	2.09E-02	-9.27E-01	-1.01E+00
Retinoblastoma	2D02.2	Uvea	9.76E-05	-2.89E+00	-1.99E+00
Rheumatoid arthritis	FA20	Synovial tissue	8.01E-01	-5.63E-02	-2.12E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	1.25E-01	1.54E-01	3.86E-01
Schizophrenia	6A20	Prefrontal cortex	3.52E-01	-5.49E-02	-2.11E-01
Schizophrenia	6A20	Superior temporal cortex	4.11E-01	4.23E-02	3.04E-01
Scleroderma	4A42.Z	Whole blood	8.50E-01	9.08E-03	8.70E-02
Seizure	8A60-8A6Z	Whole blood	6.55E-01	1.90E-02	9.66E-02
Sensitive skin	EK0Z	Skin	6.49E-01	2.98E-01	4.85E-01
Sepsis with septic shock	1G41	Whole blood	7.72E-05	4.43E-02	1.77E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.49E-01	3.13E-02	1.47E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.40E-01	-2.28E-02	-1.53E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	1.20E-01	-1.49E-01	-1.17E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.56E-01	-2.67E-01	-9.98E-01
Skin cancer	2C30-2C3Z	Skin	1.49E-29	-1.67E+00	-1.23E+00
Thrombocythemia	3B63	Whole blood	8.14E-03	9.87E-02	6.53E-01
Thrombocytopenia	3B64	Whole blood	1.14E-01	-2.29E-01	-1.07E+00
Thyroid cancer	2D10	Thyroid	2.56E-06	4.39E-02	1.96E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.04E-04	-2.41E-01	-1.69E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	5.48E-01	-3.87E-02	-2.00E-01
Type 2 diabetes	5A11	Liver tissue	4.20E-01	6.98E-03	1.60E-02
Ureter cancer	2C92	Urothelium	3.07E-01	-3.43E-02	-1.67E-01
Uterine cancer	2C78	Endometrium tissue	1.04E-09	-1.15E+00	-4.83E-01
Vitiligo	ED63.0	Skin	9.81E-01	-6.35E-01	-6.92E-01