Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DECG04O)

• DME Name: Xanthine dehydrogenase/oxidase (XDH) DME Info
• Gene Name: XDH

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	8.73E-03	2.72E-02	1.13E-01
Alopecia	ED70	Skin from scalp	8.23E-01	1.12E-01	3.65E-01
Alzheimer's disease	8A20	Entorhinal cortex	6.95E-01	-2.50E-03	-1.46E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	3.78E-01	-1.38E-01	-8.47E-01
Aortic stenosis	BB70	Calcified aortic valve	8.09E-01	-1.72E-02	-2.29E-02
Apnea	7A40	Hyperplastic tonsil	9.18E-01	3.16E-01	3.35E-01
Arthropathy	FA00-FA5Z	Peripheral blood	4.22E-01	1.83E-02	1.56E-01
Asthma	CA23	Nasal and bronchial airway	1.11E-05	1.36E+00	8.45E-01
Atopic dermatitis	EA80	Skin	3.62E-03	2.50E-01	9.28E-01
Autism	6A02	Whole blood	5.09E-01	-8.57E-02	-3.56E-01
Autoimmune uveitis	9A96	Peripheral monocyte	2.44E-02	-2.91E-01	-1.72E+00
Autosomal dominant monocytopenia	4B04	Whole blood	8.85E-01	1.46E-02	1.69E-01
Bacterial infection of gingival	1C1H	Gingival tissue	9.02E-14	9.70E-01	1.36E+00
Batten disease	5C56.1	Whole blood	4.12E-01	2.40E-02	3.95E-01
Behcet's disease	4A62	Peripheral blood	2.13E-01	-8.98E-02	-4.07E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	3.30E-01	-3.41E-02	-1.88E-01
Bladder cancer	2C94	Bladder tissue	6.54E-03	3.45E-01	9.62E-01
Breast cancer	2C60-2C6Z	Breast tissue	6.21E-21	-8.48E-01	-8.40E-01
Cardioembolic stroke	8B11.20	Whole blood	1.44E-04	1.36E-01	1.11E+00
Cervical cancer	2C77	Cervical tissue	1.87E-01	-3.14E-01	-4.21E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.78E-01	7.14E-02	2.81E-01
Chronic hepatitis C	1E51.1	Whole blood	4.45E-01	1.37E-01	5.65E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	7.28E-03	1.43E-01	6.20E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.63E-02	-5.56E-02	-1.31E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	6.56E-02	3.79E-01	1.88E+00
Colon cancer	2B90	Colon tissue	8.25E-107	-1.85E+00	-3.46E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.83E-01	-1.60E-01	-6.70E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	7.08E-01	-8.89E-02	-4.46E-01
Endometriosis	GA10	Endometrium tissue	6.38E-02	-2.24E-01	-1.42E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.45E-01	-4.64E-02	-3.09E-01
Familial hypercholesterolemia	5C80.00	Whole blood	5.75E-02	-2.24E-01	-9.07E-01
Gastric cancer	2B72	Gastric tissue	5.17E-01	6.42E-01	6.39E-01
Glioblastopma	2A00.00	Nervous tissue	1.68E-01	-6.91E-02	-2.03E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	6.56E-01	-2.09E-02	-2.69E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.39E-05	-5.14E-01	-3.26E+00
Head and neck cancer	2D42	Head and neck tissue	2.65E-11	7.96E-01	1.08E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.18E-01	-8.41E-02	-2.49E-01
Huntington's disease	8A01.10	Whole blood	2.03E-02	8.13E-02	6.96E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	5.33E-03	3.49E-01	2.59E+00
Immunodeficiency	4A00-4A20	Peripheral blood	4.70E-03	1.03E-01	1.78E+00
Influenza	1E30	Whole blood	5.16E-02	3.52E-01	3.48E+00
Interstitial cystitis	GC00.3	Bladder tissue	9.88E-01	3.90E-01	9.16E-01
Intracranial aneurysm	8B01.0	Intracranial artery	8.03E-01	9.35E-03	4.30E-02
Irritable bowel syndrome	DD91.0	Rectal colon tissue	6.43E-01	-9.59E-02	-1.90E-01
Ischemic stroke	8B11	Peripheral blood	1.35E-02	1.41E-01	7.22E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	5.47E-02	6.96E-02	3.55E-01
Lateral sclerosis	8B60.4	Skin	1.30E-01	1.95E-01	9.24E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	6.68E-01	3.07E-02	1.55E-01
Liver cancer	2C12.0	Liver tissue	5.11E-29	-1.94E+00	-3.08E+00
Liver failure	DB99.7-DB99.8	Liver tissue	7.71E-04	-1.69E+00	-5.45E+00
Lung cancer	2C25	Lung tissue	8.56E-165	1.08E+00	4.15E+00
Lupus erythematosus	4A40	Whole blood	1.30E-02	-1.54E-01	-2.63E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	7.95E-01	2.00E-02	1.19E-01
Major depressive disorder	6A70-6A7Z	Whole blood	7.31E-01	1.55E-02	7.61E-02
Melanoma	2C30	Skin	7.45E-01	3.15E-01	3.78E-01
Multiple myeloma	2A83.1	Peripheral blood	2.02E-01	1.78E-01	8.25E-01
Multiple myeloma	2A83.1	Bone marrow	2.68E-03	-3.87E-01	-2.05E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	6.46E-01	3.12E-02	1.74E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	5.28E-01	2.61E-02	1.00E-01
Myelofibrosis	2A20.2	Whole blood	1.21E-01	-1.03E-01	-7.89E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.09E-01	1.47E-01	2.29E-01
Myopathy	8C70.6	Muscle tissue	4.89E-01	-1.19E-01	-6.44E-01
Neonatal sepsis	KA60	Whole blood	4.50E-02	9.06E-02	3.81E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.23E-04	-1.07E+00	-2.05E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.04E-01	-4.46E-02	-1.33E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	8.89E-01	-1.57E-02	-1.69E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.81E-01	1.06E-01	6.69E-01
Oral cancer	2B6E	Oral tissue	2.03E-03	1.05E+00	1.09E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	7.53E-01	4.48E-03	2.58E-02
Osteoporosis	FB83.1	Bone marrow	2.04E-01	2.47E-01	1.05E+00
Ovarian cancer	2C73	Ovarian tissue	1.01E-07	8.28E-01	3.14E+00
Pancreatic cancer	2C10	Pancreas	1.42E-06	1.39E+00	1.95E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	8.49E-01	5.30E-05	3.01E-04
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	4.22E-01	-2.27E-02	-2.23E-01
Pituitary cancer	2D12	Pituitary tissue	2.80E-02	-4.66E-01	-1.15E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	5.81E-01	-3.73E-01	-1.17E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.98E-01	-1.83E-03	-1.47E-02
Polycythemia vera	2A20.4	Whole blood	4.47E-01	-2.18E-02	-1.51E-01
Pompe disease	5C51.3	Biceps muscle	5.27E-01	1.97E-02	1.24E-01
Preterm birth	KA21.4Z	Myometrium	2.43E-01	-2.26E-01	-2.23E-01
Prostate cancer	2C82	Prostate	1.64E-03	-8.08E-01	-1.12E+00
Psoriasis	EA90	Skin	8.27E-22	4.98E-01	1.19E+00
Rectal cancer	2B92	Rectal colon tissue	1.64E-06	-1.52E+00	-4.60E+00
Renal cancer	2C90-2C91	Kidney	1.40E-01	-3.43E-01	-1.03E+00
Retinoblastoma	2D02.2	Uvea	1.45E-02	-2.32E-01	-1.81E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.08E-01	1.95E-01	1.29E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	1.37E-01	1.03E-01	2.98E-01
Schizophrenia	6A20	Prefrontal cortex	5.93E-01	3.37E-02	8.83E-02
Schizophrenia	6A20	Superior temporal cortex	5.90E-02	-2.67E-02	-2.28E-01
Scleroderma	4A42.Z	Whole blood	2.98E-04	-1.73E-01	-1.54E+00
Seizure	8A60-8A6Z	Whole blood	9.54E-01	-6.93E-02	-4.61E-01
Sensitive skin	EK0Z	Skin	5.21E-01	-1.23E-01	-3.82E-01
Sepsis with septic shock	1G41	Whole blood	1.62E-04	1.16E-01	4.03E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.21E-01	1.61E-01	4.75E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.46E-01	9.93E-02	4.46E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	4.22E-01	1.30E-03	1.65E-02
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.04E-01	5.33E-01	1.15E+00
Skin cancer	2C30-2C3Z	Skin	2.50E-21	-7.46E-01	-1.40E+00
Thrombocythemia	3B63	Whole blood	8.30E-01	-3.65E-02	-2.81E-01
Thrombocytopenia	3B64	Whole blood	9.76E-01	3.25E-02	2.60E-01
Thyroid cancer	2D10	Thyroid	2.63E-17	2.42E-01	9.61E-01
Tibial muscular dystrophy	8C75	Muscle tissue	3.32E-01	-1.08E-02	-1.21E-02
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	4.22E-01	8.42E-02	6.05E-01
Type 2 diabetes	5A11	Liver tissue	9.50E-01	-1.14E-02	-4.20E-02
Ureter cancer	2C92	Urothelium	2.03E-01	-1.32E-01	-1.63E-01
Uterine cancer	2C78	Endometrium tissue	8.41E-01	2.94E-01	1.97E-01
Vitiligo	ED63.0	Skin	1.48E-01	-2.03E-01	-9.63E-01