Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEE1B8O)

• DME Name: Glucose-6-phosphatase beta (G6PC3) DME Info
• Gene Name: G6PC3

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	5.41E-27	4.51E-01	1.58E+00
Alopecia	ED70	Skin from scalp	2.45E-01	-6.82E-02	-1.81E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.35E-01	2.34E-02	1.13E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.61E-01	9.94E-02	4.52E-01
Aortic stenosis	BB70	Calcified aortic valve	4.13E-01	1.69E-01	4.07E-01
Apnea	7A40	Hyperplastic tonsil	1.06E-02	-4.18E-01	-1.98E+00
Arthropathy	FA00-FA5Z	Peripheral blood	1.97E-01	-1.06E-01	-5.55E-01
Asthma	CA23	Nasal and bronchial airway	2.79E-02	9.47E-02	1.60E-01
Atopic dermatitis	EA80	Skin	5.46E-02	1.58E-01	8.49E-01
Autism	6A02	Whole blood	1.45E-02	-1.93E-01	-9.13E-01
Autoimmune uveitis	9A96	Peripheral monocyte	7.96E-01	-4.61E-02	-5.36E-01
Autosomal dominant monocytopenia	4B04	Whole blood	5.17E-01	3.69E-03	2.59E-02
Bacterial infection of gingival	1C1H	Gingival tissue	8.84E-16	3.52E-01	1.29E+00
Batten disease	5C56.1	Whole blood	4.34E-01	4.54E-02	5.66E-01
Behcet's disease	4A62	Peripheral blood	4.63E-01	9.30E-02	4.48E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.32E-01	-5.11E-02	-2.38E-01
Bladder cancer	2C94	Bladder tissue	1.10E-01	1.96E-01	1.00E+00
Breast cancer	2C60-2C6Z	Breast tissue	5.27E-20	2.29E-01	5.94E-01
Cardioembolic stroke	8B11.20	Whole blood	1.19E-02	-1.79E-01	-8.54E-01
Cervical cancer	2C77	Cervical tissue	3.00E-01	5.89E-02	3.25E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.69E-01	8.45E-02	2.32E-01
Chronic hepatitis C	1E51.1	Whole blood	7.52E-01	-4.78E-02	-3.87E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.13E-01	-1.25E-01	-4.34E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	5.20E-01	-7.01E-02	-2.08E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.83E-01	1.07E-01	5.93E-01
Colon cancer	2B90	Colon tissue	1.36E-20	2.93E-01	1.13E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	2.36E-01	3.69E-01	1.09E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	7.22E-01	-9.64E-02	-2.64E-01
Endometriosis	GA10	Endometrium tissue	3.54E-03	-2.22E-01	-7.44E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	5.20E-01	-6.05E-03	-3.54E-02
Familial hypercholesterolemia	5C80.00	Whole blood	4.10E-05	7.42E-01	2.80E+00
Gastric cancer	2B72	Gastric tissue	2.30E-01	1.34E-03	7.47E-03
Glioblastopma	2A00.00	Nervous tissue	1.71E-39	3.49E-01	8.08E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	7.06E-01	1.82E-01	3.51E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	5.50E-02	3.39E-01	5.77E-01
Head and neck cancer	2D42	Head and neck tissue	2.94E-10	-2.52E-01	-4.43E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.88E-02	4.22E-02	2.08E-01
Huntington's disease	8A01.10	Whole blood	8.21E-01	2.77E-02	9.09E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.81E-01	1.40E-01	4.25E-01
Immunodeficiency	4A00-4A20	Peripheral blood	2.20E-02	1.35E-01	1.19E+00
Influenza	1E30	Whole blood	1.59E-01	-1.49E-01	-1.01E+00
Interstitial cystitis	GC00.3	Bladder tissue	6.92E-01	3.43E-02	1.59E-01
Intracranial aneurysm	8B01.0	Intracranial artery	3.55E-03	5.17E-01	1.49E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	3.11E-01	-6.51E-02	-1.83E-01
Ischemic stroke	8B11	Peripheral blood	1.91E-01	-9.66E-02	-5.56E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	5.42E-02	-1.17E-01	-3.87E-01
Lateral sclerosis	8B60.4	Skin	3.03E-01	2.03E-01	6.71E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	6.82E-01	2.87E-01	5.73E-01
Liver cancer	2C12.0	Liver tissue	6.57E-08	1.50E-01	6.08E-01
Liver failure	DB99.7-DB99.8	Liver tissue	2.13E-06	8.41E-01	3.13E+00
Lung cancer	2C25	Lung tissue	4.59E-02	-4.90E-02	-1.58E-01
Lupus erythematosus	4A40	Whole blood	4.57E-02	1.75E-02	5.27E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	6.22E-01	-1.43E-03	-6.58E-03
Major depressive disorder	6A70-6A7Z	Whole blood	4.97E-01	2.64E-02	9.44E-02
Melanoma	2C30	Skin	7.49E-02	3.77E-01	4.19E-01
Multiple myeloma	2A83.1	Peripheral blood	7.08E-01	-3.76E-02	-1.42E-01
Multiple myeloma	2A83.1	Bone marrow	2.62E-04	4.10E-01	2.07E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.75E-01	6.15E-02	2.34E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.56E-02	-1.42E-01	-5.93E-01
Myelofibrosis	2A20.2	Whole blood	1.25E-01	1.04E-01	8.92E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.76E-01	1.49E-01	2.23E-01
Myopathy	8C70.6	Muscle tissue	1.17E-02	1.46E-01	1.24E+00
Neonatal sepsis	KA60	Whole blood	8.70E-01	-3.12E-02	-1.38E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.14E-07	-1.02E+00	-4.12E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.53E-02	-1.07E-01	-9.47E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	8.75E-03	1.84E-01	1.34E+00
Olive pollen allergy	CA08.00	Peripheral blood	1.60E-01	4.02E-01	7.45E-01
Oral cancer	2B6E	Oral tissue	4.64E-02	-1.88E-01	-6.69E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	2.69E-01	1.12E-01	1.08E-01
Osteoporosis	FB83.1	Bone marrow	6.35E-01	1.28E-01	3.50E-01
Ovarian cancer	2C73	Ovarian tissue	8.74E-03	2.11E-01	8.43E-01
Pancreatic cancer	2C10	Pancreas	2.24E-02	2.82E-01	7.85E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	6.19E-04	-2.21E-01	-1.70E+00
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.47E-05	1.87E-01	1.35E+00
Pituitary cancer	2D12	Pituitary tissue	5.72E-02	1.75E-01	6.68E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	8.13E-02	2.41E-01	7.79E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	9.08E-01	-3.39E-02	-2.93E-01
Polycythemia vera	2A20.4	Whole blood	3.19E-01	-2.64E-02	-1.96E-01
Pompe disease	5C51.3	Biceps muscle	6.56E-01	1.28E-01	7.05E-01
Preterm birth	KA21.4Z	Myometrium	1.77E-01	-1.30E-01	-6.69E-01
Prostate cancer	2C82	Prostate	3.40E-03	-4.98E-01	-8.58E-01
Psoriasis	EA90	Skin	6.74E-16	-5.20E-01	-9.81E-01
Rectal cancer	2B92	Rectal colon tissue	1.69E-01	2.41E-01	1.23E+00
Renal cancer	2C90-2C91	Kidney	6.69E-04	-2.37E-01	-9.80E-01
Retinoblastoma	2D02.2	Uvea	1.94E-02	5.59E-01	3.44E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.91E-05	9.54E-01	3.79E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.12E-03	-9.25E-02	-6.45E-01
Schizophrenia	6A20	Prefrontal cortex	7.01E-02	-1.52E-02	-7.58E-02
Schizophrenia	6A20	Superior temporal cortex	2.53E-02	-9.57E-02	-8.26E-01
Scleroderma	4A42.Z	Whole blood	5.49E-01	7.18E-02	3.99E-01
Seizure	8A60-8A6Z	Whole blood	5.50E-01	-1.41E-01	-7.43E-01
Sensitive skin	EK0Z	Skin	1.54E-01	-9.74E-02	-1.04E+00
Sepsis with septic shock	1G41	Whole blood	2.81E-03	-4.94E-02	-2.42E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	4.56E-01	-1.05E-01	-7.49E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	9.13E-03	2.51E-01	1.35E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.17E-01	9.26E-02	2.67E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.38E-01	6.52E-02	2.56E-01
Skin cancer	2C30-2C3Z	Skin	2.82E-13	4.87E-01	1.02E+00
Thrombocythemia	3B63	Whole blood	6.59E-01	4.99E-02	4.03E-01
Thrombocytopenia	3B64	Whole blood	6.14E-01	1.75E-01	2.26E-01
Thyroid cancer	2D10	Thyroid	1.12E-01	-1.47E-01	-3.02E-01
Tibial muscular dystrophy	8C75	Muscle tissue	9.55E-03	1.86E-01	9.27E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.34E-01	3.13E-01	1.39E+00
Type 2 diabetes	5A11	Liver tissue	9.79E-02	-5.76E-02	-1.12E+00
Ureter cancer	2C92	Urothelium	9.63E-01	-4.02E-02	-1.55E-01
Uterine cancer	2C78	Endometrium tissue	6.57E-17	-6.39E-01	-6.45E-01
Vitiligo	ED63.0	Skin	9.37E-01	-1.05E-02	-4.62E-02