Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEEN9RD)

• DME Name: Alcohol dehydrogenase class-I beta (ADH1B) DME Info
• Gene Name: ADH1B

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.06E-01	-1.43E-02	-4.01E-02
Alopecia	ED70	Skin from scalp	5.41E-02	3.75E-01	5.67E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.61E-03	7.98E-02	3.20E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.80E-01	3.80E-02	4.04E-01
Aortic stenosis	BB70	Calcified aortic valve	7.86E-02	-1.79E+00	-1.07E+00
Apnea	7A40	Hyperplastic tonsil	2.93E-01	5.89E-02	4.63E-01
Arthropathy	FA00-FA5Z	Peripheral blood	1.77E-02	5.51E-02	8.86E-01
Asthma	CA23	Nasal and bronchial airway	1.97E-03	-1.49E-01	-5.91E-01
Atopic dermatitis	EA80	Skin	1.53E-05	-9.31E-01	-1.67E+00
Autism	6A02	Whole blood	5.82E-01	-3.60E-02	-3.93E-01
Autoimmune uveitis	9A96	Peripheral monocyte	3.62E-02	-1.85E-01	-1.18E+00
Autosomal dominant monocytopenia	4B04	Whole blood	5.13E-04	9.23E-02	1.15E+00
Bacterial infection of gingival	1C1H	Gingival tissue	7.09E-01	1.96E-02	8.88E-02
Batten disease	5C56.1	Whole blood	1.40E-01	3.29E-02	6.08E-01
Behcet's disease	4A62	Peripheral blood	7.08E-01	4.56E-02	3.35E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.53E-01	5.85E-02	3.32E-01
Bladder cancer	2C94	Bladder tissue	5.51E-10	-4.91E+00	-1.02E+01
Breast cancer	2C60-2C6Z	Breast tissue	7.21E-105	-4.55E+00	-2.38E+00
Cardioembolic stroke	8B11.20	Whole blood	4.87E-01	2.00E-02	2.05E-01
Cervical cancer	2C77	Cervical tissue	5.22E-01	-2.92E-02	-1.17E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	3.69E-01	8.18E-03	7.44E-02
Chronic hepatitis C	1E51.1	Whole blood	4.98E-01	-7.12E-02	-5.72E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.22E-02	-2.19E-01	-6.31E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.54E-01	-2.76E-02	-7.21E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	3.81E-02	-1.20E+00	-1.15E+00
Colon cancer	2B90	Colon tissue	4.82E-78	-2.63E+00	-3.17E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.20E-01	-5.60E-02	-5.20E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	9.96E-01	-1.91E-02	-2.06E-01
Endometriosis	GA10	Endometrium tissue	7.06E-04	4.50E-01	3.98E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	1.94E-01	-6.51E-02	-8.74E-01
Familial hypercholesterolemia	5C80.00	Whole blood	6.54E-02	-4.83E-02	-4.25E-01
Gastric cancer	2B72	Gastric tissue	1.53E-01	-2.32E+00	-1.67E+00
Glioblastopma	2A00.00	Nervous tissue	7.53E-05	-1.08E-01	-1.78E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	9.10E-01	-1.57E-01	-7.54E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.23E-01	-2.73E-01	-8.45E-01
Head and neck cancer	2D42	Head and neck tissue	4.71E-08	-1.04E+00	-6.99E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	6.13E-01	-5.01E-03	-2.53E-02
Huntington's disease	8A01.10	Whole blood	8.55E-01	3.55E-02	3.23E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.60E-01	-7.51E-01	-1.06E+00
Immunodeficiency	4A00-4A20	Peripheral blood	2.48E-01	6.38E-02	6.28E-01
Influenza	1E30	Whole blood	2.64E-01	6.88E-02	6.10E-01
Interstitial cystitis	GC00.3	Bladder tissue	8.17E-01	2.80E-01	4.27E-01
Intracranial aneurysm	8B01.0	Intracranial artery	8.46E-03	-1.12E+00	-1.40E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.49E-03	-1.38E-01	-5.13E-01
Ischemic stroke	8B11	Peripheral blood	1.44E-01	5.06E-02	5.44E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.14E-02	6.16E-02	2.30E-01
Lateral sclerosis	8B60.4	Skin	2.20E-01	2.71E-02	4.20E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	9.63E-02	-8.04E-02	-2.22E-01
Liver cancer	2C12.0	Liver tissue	7.46E-50	-1.79E+00	-4.29E+00
Liver failure	DB99.7-DB99.8	Liver tissue	1.92E-06	-3.38E+00	-6.42E+00
Lung cancer	2C25	Lung tissue	1.23E-269	-3.91E+00	-6.78E+00
Lupus erythematosus	4A40	Whole blood	4.81E-01	-1.27E-02	-6.03E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	8.67E-01	3.48E-02	1.63E-01
Major depressive disorder	6A70-6A7Z	Whole blood	9.84E-02	3.72E-02	2.34E-01
Melanoma	2C30	Skin	5.15E-04	-3.06E+00	-1.56E+00
Multiple myeloma	2A83.1	Peripheral blood	9.75E-02	7.34E-02	8.36E-01
Multiple myeloma	2A83.1	Bone marrow	1.50E-03	-3.27E-01	-1.85E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	6.29E-01	-4.42E-02	-3.36E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	5.60E-01	2.52E-02	2.68E-01
Myelofibrosis	2A20.2	Whole blood	2.13E-01	5.73E-02	4.94E-01
Myocardial infarction	BA41-BA50	Peripheral blood	7.81E-02	2.41E-02	7.52E-02
Myopathy	8C70.6	Muscle tissue	2.58E-01	1.74E-01	4.05E-01
Neonatal sepsis	KA60	Whole blood	7.96E-01	6.86E-03	4.99E-02
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.28E-04	-1.19E+00	-1.79E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	3.07E-01	1.73E-01	3.97E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.12E-01	-1.97E-01	-1.16E+00
Olive pollen allergy	CA08.00	Peripheral blood	3.91E-02	1.20E-01	1.80E+00
Oral cancer	2B6E	Oral tissue	2.88E-05	-2.51E+00	-1.48E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.11E-02	-1.93E+00	-1.20E+00
Osteoporosis	FB83.1	Bone marrow	2.62E-01	-1.59E-01	-2.02E-01
Ovarian cancer	2C73	Ovarian tissue	2.89E-03	-2.78E+00	-1.83E+00
Pancreatic cancer	2C10	Pancreas	2.46E-03	-1.10E+00	-8.63E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	9.31E-02	1.42E-01	6.88E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.80E-02	-6.62E-02	-8.80E-01
Pituitary cancer	2D12	Pituitary tissue	1.77E-05	-2.23E+00	-2.42E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	5.90E-06	-2.40E+00	-3.18E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.56E-01	6.98E-02	2.02E-01
Polycythemia vera	2A20.4	Whole blood	1.57E-07	1.30E-01	1.06E+00
Pompe disease	5C51.3	Biceps muscle	2.93E-01	-3.93E-01	-1.10E+00
Preterm birth	KA21.4Z	Myometrium	1.92E-03	1.87E+00	3.24E+00
Prostate cancer	2C82	Prostate	3.38E-03	-7.68E-01	-4.26E-01
Psoriasis	EA90	Skin	1.00E-19	-1.14E+00	-1.39E+00
Rectal cancer	2B92	Rectal colon tissue	2.46E-05	-3.46E+00	-5.15E+00
Renal cancer	2C90-2C91	Kidney	1.31E-03	-2.86E+00	-2.09E+00
Retinoblastoma	2D02.2	Uvea	1.81E-01	-6.02E-02	-9.29E-01
Rheumatoid arthritis	FA20	Synovial tissue	8.57E-04	-3.03E+00	-2.50E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.25E-01	-3.99E-02	-5.07E-01
Schizophrenia	6A20	Prefrontal cortex	2.19E-01	2.00E-02	8.14E-02
Schizophrenia	6A20	Superior temporal cortex	8.73E-02	9.89E-02	7.83E-01
Scleroderma	4A42.Z	Whole blood	5.23E-02	4.66E-02	5.49E-01
Seizure	8A60-8A6Z	Whole blood	6.30E-02	-5.20E-02	-5.20E-01
Sensitive skin	EK0Z	Skin	6.03E-01	1.37E-02	2.89E-02
Sepsis with septic shock	1G41	Whole blood	3.98E-05	5.46E-02	3.16E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.37E-01	1.19E-01	5.49E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.93E-02	5.97E-02	7.34E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	2.72E-02	-3.66E-01	-2.04E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.96E-01	1.49E+00	1.42E+00
Skin cancer	2C30-2C3Z	Skin	8.31E-154	-4.65E+00	-4.52E+00
Thrombocythemia	3B63	Whole blood	1.40E-06	1.72E-01	1.42E+00
Thrombocytopenia	3B64	Whole blood	4.01E-01	3.74E+00	1.64E+00
Thyroid cancer	2D10	Thyroid	6.84E-63	-2.46E+00	-3.84E+00
Tibial muscular dystrophy	8C75	Muscle tissue	3.21E-01	6.54E-01	7.22E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	7.74E-01	1.62E-02	1.79E-01
Type 2 diabetes	5A11	Liver tissue	1.73E-01	1.32E-01	1.06E+00
Ureter cancer	2C92	Urothelium	2.16E-01	-5.76E-02	-4.60E-01
Uterine cancer	2C78	Endometrium tissue	5.37E-01	-1.02E-01	-8.48E-02
Vitiligo	ED63.0	Skin	3.16E-01	6.88E-02	8.12E-02