Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEFADPU)

• DME Name: Methionine-R-sulfoxide reductase B1 (MSRB1) DME Info
• Gene Name: MSRB1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.36E-62	-2.23E+00	-2.60E+00
Alopecia	ED70	Skin from scalp	1.45E-02	1.91E-01	4.59E-01
Alzheimer's disease	8A20	Entorhinal cortex	9.33E-02	5.98E-02	2.58E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	4.55E-01	2.42E-01	3.35E-01
Aortic stenosis	BB70	Calcified aortic valve	4.37E-01	1.14E-01	3.28E-01
Apnea	7A40	Hyperplastic tonsil	9.45E-01	7.85E-02	1.66E-01
Arthropathy	FA00-FA5Z	Peripheral blood	9.10E-02	1.75E-01	5.38E-01
Asthma	CA23	Nasal and bronchial airway	3.38E-05	1.66E-01	1.35E-01
Atopic dermatitis	EA80	Skin	1.90E-01	1.69E-01	3.43E-01
Autism	6A02	Whole blood	7.02E-01	9.00E-03	2.11E-02
Autoimmune uveitis	9A96	Peripheral monocyte	6.02E-01	1.44E-01	3.32E-01
Autosomal dominant monocytopenia	4B04	Whole blood	2.28E-01	-1.03E+00	-1.21E+00
Bacterial infection of gingival	1C1H	Gingival tissue	3.93E-10	3.32E-01	1.02E+00
Batten disease	5C56.1	Whole blood	6.32E-01	8.64E-03	2.61E-02
Behcet's disease	4A62	Peripheral blood	4.59E-01	8.32E-02	2.49E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	7.78E-01	-6.67E-03	-3.26E-02
Bladder cancer	2C94	Bladder tissue	1.15E-02	5.12E-01	1.43E+00
Breast cancer	2C60-2C6Z	Breast tissue	1.25E-48	3.98E-01	1.29E+00
Cardioembolic stroke	8B11.20	Whole blood	5.15E-05	3.01E-01	1.07E+00
Cervical cancer	2C77	Cervical tissue	4.56E-03	3.85E-01	8.36E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.03E-01	3.07E-01	1.75E-01
Chronic hepatitis C	1E51.1	Whole blood	5.89E-01	-1.33E-01	-2.46E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	7.91E-01	-7.99E-02	-1.86E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	3.34E-07	5.07E-01	1.20E+00
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	2.29E-01	2.72E-01	1.55E+00
Colon cancer	2B90	Colon tissue	5.60E-11	1.97E-01	6.06E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	4.27E-01	3.32E-01	3.31E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.23E-02	-7.56E-01	-1.40E+00
Endometriosis	GA10	Endometrium tissue	5.36E-02	2.34E-01	5.98E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	9.28E-02	-2.66E-01	-5.97E-01
Familial hypercholesterolemia	5C80.00	Whole blood	5.92E-09	-7.39E-01	-1.42E+00
Gastric cancer	2B72	Gastric tissue	3.24E-01	1.79E-01	3.37E-01
Glioblastopma	2A00.00	Nervous tissue	2.09E-56	5.06E-01	1.30E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	6.28E-01	-2.62E-01	-3.15E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.54E-01	3.25E-01	2.79E-01
Head and neck cancer	2D42	Head and neck tissue	8.84E-13	5.07E-01	8.45E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	7.01E-01	1.07E-02	3.63E-02
Huntington's disease	8A01.10	Whole blood	7.19E-01	-1.80E-01	-1.88E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.62E-02	-6.76E-01	-1.52E+00
Immunodeficiency	4A00-4A20	Peripheral blood	3.26E-02	1.11E-01	1.13E+00
Influenza	1E30	Whole blood	5.31E-01	6.85E-02	1.50E-01
Interstitial cystitis	GC00.3	Bladder tissue	2.87E-03	5.46E-01	2.40E+00
Intracranial aneurysm	8B01.0	Intracranial artery	4.22E-04	-6.50E-01	-1.24E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	9.39E-03	-3.69E-01	-5.53E-01
Ischemic stroke	8B11	Peripheral blood	2.78E-01	-7.76E-02	-1.63E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.80E-01	1.62E-02	1.13E-02
Lateral sclerosis	8B60.4	Skin	1.89E-01	1.77E-01	9.01E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	4.22E-01	-1.42E-01	-3.11E-01
Liver cancer	2C12.0	Liver tissue	2.54E-10	-3.04E-01	-9.46E-01
Liver failure	DB99.7-DB99.8	Liver tissue	4.78E-04	-1.56E+00	-3.20E+00
Lung cancer	2C25	Lung tissue	3.10E-14	2.25E-01	7.45E-01
Lupus erythematosus	4A40	Whole blood	8.37E-03	2.53E-01	1.73E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	8.91E-01	-1.25E-03	-6.15E-03
Major depressive disorder	6A70-6A7Z	Whole blood	6.67E-01	-3.42E-02	-6.56E-02
Melanoma	2C30	Skin	1.15E-02	-2.92E-01	-2.92E-01
Multiple myeloma	2A83.1	Peripheral blood	7.32E-01	-8.12E-02	-1.45E-01
Multiple myeloma	2A83.1	Bone marrow	4.70E-01	-7.77E-02	-3.49E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.64E-01	-5.23E-01	-8.57E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	3.58E-08	4.55E-01	1.31E+00
Myelofibrosis	2A20.2	Whole blood	3.37E-01	2.99E-01	9.65E-01
Myocardial infarction	BA41-BA50	Peripheral blood	5.00E-02	1.13E+00	5.44E-01
Myopathy	8C70.6	Muscle tissue	5.01E-03	6.02E-01	1.53E+00
Neonatal sepsis	KA60	Whole blood	1.12E-06	8.44E-01	7.95E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	8.64E-01	-6.41E-02	-1.60E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.86E-01	-8.45E-02	-3.08E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.82E-01	1.22E-01	3.36E-01
Olive pollen allergy	CA08.00	Peripheral blood	3.83E-01	5.51E-01	7.01E-01
Oral cancer	2B6E	Oral tissue	3.19E-03	5.01E-01	7.86E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	2.71E-01	3.20E-01	3.21E-01
Osteoporosis	FB83.1	Bone marrow	4.09E-02	-2.88E-01	-1.05E+00
Ovarian cancer	2C73	Ovarian tissue	1.61E-02	5.57E-01	1.17E+00
Pancreatic cancer	2C10	Pancreas	4.60E-02	-7.33E-01	-6.91E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	8.30E-01	7.82E-02	5.08E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.04E-07	1.38E+00	2.56E+00
Pituitary cancer	2D12	Pituitary tissue	1.79E-01	-4.41E-01	-5.55E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.05E-02	-6.50E-01	-8.91E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	1.54E-01	-2.22E-01	-8.62E-01
Polycythemia vera	2A20.4	Whole blood	2.69E-09	3.97E-01	1.30E+00
Pompe disease	5C51.3	Biceps muscle	2.14E-06	1.19E+00	3.95E+00
Preterm birth	KA21.4Z	Myometrium	4.19E-02	6.50E-01	2.12E+00
Prostate cancer	2C82	Prostate	8.76E-06	-6.77E-01	-1.06E+00
Psoriasis	EA90	Skin	6.65E-01	-6.32E-02	-1.13E-01
Rectal cancer	2B92	Rectal colon tissue	2.01E-03	-3.09E-01	-2.24E+00
Renal cancer	2C90-2C91	Kidney	1.16E-03	-8.43E-01	-1.45E+00
Retinoblastoma	2D02.2	Uvea	1.36E-09	1.33E+00	3.91E+00
Rheumatoid arthritis	FA20	Synovial tissue	4.84E-03	6.86E-01	1.41E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	7.23E-03	4.22E-02	2.29E-01
Schizophrenia	6A20	Prefrontal cortex	6.54E-02	1.75E-01	1.40E-01
Schizophrenia	6A20	Superior temporal cortex	4.84E-01	2.28E-02	1.14E-01
Scleroderma	4A42.Z	Whole blood	2.12E-04	3.94E-01	2.35E+00
Seizure	8A60-8A6Z	Whole blood	1.73E-01	5.40E-01	7.11E-01
Sensitive skin	EK0Z	Skin	5.26E-01	-1.09E-01	-2.73E-01
Sepsis with septic shock	1G41	Whole blood	7.31E-54	1.29E+00	1.96E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.60E-01	8.13E-01	1.23E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	5.59E-01	-1.95E-01	-7.31E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	2.32E-01	-1.89E-01	-5.29E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	8.23E-01	-3.76E-01	-1.01E+00
Skin cancer	2C30-2C3Z	Skin	7.35E-31	-6.79E-01	-1.02E+00
Thrombocythemia	3B63	Whole blood	2.47E-03	1.80E-01	5.80E-01
Thrombocytopenia	3B64	Whole blood	1.62E-01	4.79E-01	3.99E-01
Thyroid cancer	2D10	Thyroid	3.69E-01	2.49E-02	1.12E-01
Tibial muscular dystrophy	8C75	Muscle tissue	5.52E-06	6.88E-01	1.75E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.05E-02	5.43E-01	2.04E+00
Type 2 diabetes	5A11	Liver tissue	5.38E-01	1.89E-02	7.05E-02
Ureter cancer	2C92	Urothelium	2.77E-01	-2.36E-03	-3.57E-03
Uterine cancer	2C78	Endometrium tissue	7.42E-01	1.40E-02	1.65E-02
Vitiligo	ED63.0	Skin	7.89E-01	-1.01E-02	-1.94E-02