Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEGPI81)

• DME Name: Angiotensin-converting enzyme 2 (ACE2) DME Info
• Gene Name: ACE2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.38E-01	1.50E-04	1.38E-03
Alopecia	ED70	Skin from scalp	4.89E-04	3.36E-01	7.40E-01
Alzheimer's disease	8A20	Entorhinal cortex	3.62E-01	-1.43E-02	-1.04E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.66E-01	-6.28E-02	-7.23E-01
Aortic stenosis	BB70	Calcified aortic valve	9.45E-01	7.82E-02	1.80E-01
Apnea	7A40	Hyperplastic tonsil	1.92E-01	-2.01E-01	-8.30E-01
Arthropathy	FA00-FA5Z	Peripheral blood	8.03E-02	6.99E-02	7.62E-01
Asthma	CA23	Nasal and bronchial airway	8.78E-05	6.89E-01	7.04E-01
Atopic dermatitis	EA80	Skin	3.23E-01	6.66E-02	3.78E-01
Autism	6A02	Whole blood	2.85E-01	-5.04E-02	-3.78E-01
Autoimmune uveitis	9A96	Peripheral monocyte	4.88E-01	-7.07E-02	-1.16E+00
Autosomal dominant monocytopenia	4B04	Whole blood	3.02E-01	2.26E-02	1.94E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.12E-06	-1.86E-01	-4.84E-01
Batten disease	5C56.1	Whole blood	9.78E-01	1.23E-02	9.66E-02
Behcet's disease	4A62	Peripheral blood	8.49E-01	3.64E-03	2.24E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	8.21E-01	3.43E-03	3.21E-02
Bladder cancer	2C94	Bladder tissue	3.79E-01	2.19E-02	6.90E-02
Breast cancer	2C60-2C6Z	Breast tissue	2.08E-01	-3.20E-01	-7.31E-01
Cardioembolic stroke	8B11.20	Whole blood	5.71E-04	1.33E-01	1.05E+00
Cervical cancer	2C77	Cervical tissue	5.15E-02	-2.96E-01	-4.03E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.40E-02	4.03E-02	3.56E-01
Chronic hepatitis C	1E51.1	Whole blood	2.97E-01	4.77E-02	6.60E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.08E-02	6.45E-02	4.70E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	7.28E-02	-7.40E-02	-1.22E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	3.98E-01	8.30E-02	3.59E-01
Colon cancer	2B90	Colon tissue	5.11E-02	-1.12E-01	-1.16E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	8.70E-01	-4.35E-02	-2.83E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.86E-01	-2.17E-01	-1.20E+00
Endometriosis	GA10	Endometrium tissue	5.69E-03	2.58E-01	1.02E+00
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.11E-01	4.39E-02	4.10E-01
Familial hypercholesterolemia	5C80.00	Whole blood	6.90E-03	-9.59E-02	-6.96E-01
Gastric cancer	2B72	Gastric tissue	3.05E-01	1.27E+00	8.99E-01
Glioblastopma	2A00.00	Nervous tissue	6.32E-01	6.30E-03	2.97E-02
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	3.61E-01	-3.93E-02	-9.54E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	8.71E-03	-3.44E-01	-1.57E+00
Head and neck cancer	2D42	Head and neck tissue	3.35E-04	-3.59E-01	-4.62E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.80E-01	-3.74E-02	-2.17E-01
Huntington's disease	8A01.10	Whole blood	5.43E-01	-2.34E-02	-1.69E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	6.46E-01	-1.94E-01	-6.97E-01
Immunodeficiency	4A00-4A20	Peripheral blood	1.03E-01	9.65E-02	9.66E-01
Influenza	1E30	Whole blood	4.94E-02	1.06E-01	1.75E+00
Interstitial cystitis	GC00.3	Bladder tissue	7.51E-01	-1.32E-01	-4.05E-01
Intracranial aneurysm	8B01.0	Intracranial artery	9.94E-01	-5.59E-02	-5.47E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	4.58E-01	1.48E-02	2.15E-02
Ischemic stroke	8B11	Peripheral blood	6.43E-01	2.73E-02	3.09E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.32E-02	4.65E-02	2.20E-01
Lateral sclerosis	8B60.4	Skin	8.35E-01	-2.77E-02	-3.18E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	6.42E-04	1.80E-01	1.87E+00
Liver cancer	2C12.0	Liver tissue	1.22E-02	-5.94E-01	-1.01E+00
Liver failure	DB99.7-DB99.8	Liver tissue	1.08E-02	6.75E-01	2.91E+00
Lung cancer	2C25	Lung tissue	8.57E-41	3.20E-01	1.01E+00
Lupus erythematosus	4A40	Whole blood	9.56E-02	-5.10E-02	-2.04E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	9.98E-01	3.81E-02	3.52E-01
Major depressive disorder	6A70-6A7Z	Whole blood	4.06E-02	6.89E-02	3.08E-01
Melanoma	2C30	Skin	2.17E-02	-3.28E-01	-3.52E-01
Multiple myeloma	2A83.1	Peripheral blood	4.69E-01	-3.17E-02	-3.13E-01
Multiple myeloma	2A83.1	Bone marrow	2.65E-05	-3.71E-01	-3.48E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.53E-01	-1.55E-01	-9.07E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	5.51E-01	-1.65E-02	-1.69E-01
Myelofibrosis	2A20.2	Whole blood	1.61E-01	-1.63E-04	-1.75E-03
Myocardial infarction	BA41-BA50	Peripheral blood	8.89E-02	5.22E-02	1.96E-01
Myopathy	8C70.6	Muscle tissue	7.25E-01	-2.82E-02	-1.91E-01
Neonatal sepsis	KA60	Whole blood	2.01E-01	-4.13E-02	-2.69E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	7.40E-03	-3.65E-01	-1.37E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.37E-01	1.34E-01	1.49E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	4.07E-01	-1.47E-03	-9.47E-03
Olive pollen allergy	CA08.00	Peripheral blood	4.68E-01	-1.23E-02	-6.24E-02
Oral cancer	2B6E	Oral tissue	1.03E-04	3.52E-01	7.96E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.67E-02	-1.67E-01	-1.05E+00
Osteoporosis	FB83.1	Bone marrow	5.23E-01	-1.99E-02	-7.88E-01
Ovarian cancer	2C73	Ovarian tissue	7.86E-01	4.38E-02	5.50E-02
Pancreatic cancer	2C10	Pancreas	3.19E-01	-6.96E-01	-3.99E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	5.61E-01	5.99E-04	1.36E-03
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	7.56E-01	-3.74E-03	-3.84E-02
Pituitary cancer	2D12	Pituitary tissue	2.26E-02	7.56E-02	7.03E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.45E-01	6.81E-02	6.00E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	9.07E-01	1.71E-02	1.27E-01
Polycythemia vera	2A20.4	Whole blood	2.47E-06	7.12E-02	6.93E-01
Pompe disease	5C51.3	Biceps muscle	8.90E-01	1.69E-02	1.72E-01
Preterm birth	KA21.4Z	Myometrium	5.29E-01	5.41E-01	1.26E+00
Prostate cancer	2C82	Prostate	3.24E-02	-2.25E-01	-2.73E-01
Psoriasis	EA90	Skin	1.32E-39	7.65E-01	3.51E+00
Rectal cancer	2B92	Rectal colon tissue	5.76E-02	1.03E+00	1.13E+00
Renal cancer	2C90-2C91	Kidney	2.20E-01	-4.92E-01	-3.16E-01
Retinoblastoma	2D02.2	Uvea	5.21E-01	1.21E-02	1.41E-01
Rheumatoid arthritis	FA20	Synovial tissue	4.52E-02	-2.94E-01	-1.33E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	2.18E-01	-3.33E-02	-1.35E-01
Schizophrenia	6A20	Prefrontal cortex	5.53E-01	3.15E-02	1.73E-01
Schizophrenia	6A20	Superior temporal cortex	1.02E-01	-2.20E-02	-2.84E-01
Scleroderma	4A42.Z	Whole blood	1.77E-02	1.21E-01	1.15E+00
Seizure	8A60-8A6Z	Whole blood	2.40E-01	6.91E-02	5.26E-01
Sensitive skin	EK0Z	Skin	3.72E-01	-1.31E-01	-3.56E-01
Sepsis with septic shock	1G41	Whole blood	6.34E-02	-2.91E-02	-1.83E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	5.18E-02	2.27E-01	1.20E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	8.62E-01	2.89E-02	1.62E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	2.75E-01	3.34E-02	6.95E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.81E-01	2.27E-01	5.65E-01
Skin cancer	2C30-2C3Z	Skin	2.55E-01	-1.01E-01	-2.44E-01
Thrombocythemia	3B63	Whole blood	4.64E-02	8.84E-02	8.56E-01
Thrombocytopenia	3B64	Whole blood	6.04E-01	5.11E-02	6.20E-01
Thyroid cancer	2D10	Thyroid	4.42E-04	-1.90E-01	-4.71E-01
Tibial muscular dystrophy	8C75	Muscle tissue	2.73E-04	-1.48E-01	-1.24E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	8.64E-02	5.90E-02	1.63E+00
Type 2 diabetes	5A11	Liver tissue	3.93E-02	3.99E-01	1.10E+00
Ureter cancer	2C92	Urothelium	5.06E-01	-8.65E-03	-6.15E-02
Uterine cancer	2C78	Endometrium tissue	4.09E-04	3.54E-01	3.87E-01
Vitiligo	ED63.0	Skin	8.93E-02	7.12E-01	1.46E+00