Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEHGR57)

• DME Name: Hydroxyindole O-methyltransferase (ASMT) DME Info
• Gene Name: ASMT

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	7.12E-04	-1.41E-02	-7.34E-02
Alopecia	ED70	Skin from scalp	2.86E-01	-6.57E-02	-2.67E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.31E-01	-2.47E-02	-2.05E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.66E-01	1.20E-02	9.52E-02
Aortic stenosis	BB70	Calcified aortic valve	7.90E-01	-1.10E-01	-2.25E-01
Apnea	7A40	Hyperplastic tonsil	5.80E-01	-6.97E-02	-4.77E-01
Arthropathy	FA00-FA5Z	Peripheral blood	5.56E-01	8.96E-03	9.15E-02
Asthma	CA23	Nasal and bronchial airway	8.32E-02	3.30E-02	1.63E-01
Atopic dermatitis	EA80	Skin	9.00E-01	1.43E-02	2.07E-01
Autism	6A02	Whole blood	2.52E-01	-4.74E-02	-2.51E-01
Autoimmune uveitis	9A96	Peripheral monocyte	6.11E-01	1.68E-02	1.23E-01
Autosomal dominant monocytopenia	4B04	Whole blood	9.59E-02	1.68E-01	1.05E+00
Bacterial infection of gingival	1C1H	Gingival tissue	8.70E-01	2.41E-02	1.29E-01
Batten disease	5C56.1	Whole blood	3.17E-01	7.20E-03	1.03E-01
Behcet's disease	4A62	Peripheral blood	1.15E-01	1.45E-01	1.14E+00
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.76E-01	-5.81E-03	-4.58E-02
Bladder cancer	2C94	Bladder tissue	7.75E-04	6.02E-01	2.47E+00
Breast cancer	2C60-2C6Z	Breast tissue	3.59E-10	-7.55E-02	-2.90E-01
Cardioembolic stroke	8B11.20	Whole blood	5.29E-01	-1.21E-01	-5.04E-01
Cervical cancer	2C77	Cervical tissue	4.43E-01	9.56E-02	3.79E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	8.56E-01	-2.02E-02	-1.01E-01
Chronic hepatitis C	1E51.1	Whole blood	3.27E-01	1.48E-04	1.23E-03
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.72E-01	3.29E-03	2.89E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.06E-02	3.73E-02	2.57E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	9.22E-01	1.06E-02	1.12E-01
Colon cancer	2B90	Colon tissue	3.02E-02	-2.39E-02	-1.23E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	9.35E-01	-2.20E-02	-1.78E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	8.03E-01	1.95E-01	1.44E-01
Endometriosis	GA10	Endometrium tissue	3.32E-01	2.56E-02	1.48E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.02E-01	3.07E-02	3.01E-01
Familial hypercholesterolemia	5C80.00	Whole blood	3.27E-04	-1.19E-01	-5.52E-01
Gastric cancer	2B72	Gastric tissue	5.07E-01	1.80E-01	8.93E-01
Glioblastopma	2A00.00	Nervous tissue	6.57E-01	2.68E-04	1.47E-03
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	3.11E-01	1.67E-01	1.35E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	5.12E-05	-3.97E-01	-2.80E+00
Head and neck cancer	2D42	Head and neck tissue	1.01E-02	-5.45E-02	-3.38E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	2.10E-01	-6.13E-02	-3.38E-01
Huntington's disease	8A01.10	Whole blood	9.37E-01	-2.30E-03	-3.07E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	7.43E-01	2.57E-02	2.75E-01
Immunodeficiency	4A00-4A20	Peripheral blood	7.99E-02	8.35E-02	9.18E-01
Influenza	1E30	Whole blood	1.62E-02	1.68E-01	3.40E+00
Interstitial cystitis	GC00.3	Bladder tissue	2.51E-01	6.99E-02	1.01E+00
Intracranial aneurysm	8B01.0	Intracranial artery	8.32E-01	-9.33E-02	-5.39E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	3.03E-01	-8.48E-03	-5.90E-02
Ischemic stroke	8B11	Peripheral blood	1.54E-02	8.09E-02	5.96E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	7.19E-02	2.57E-02	1.38E-01
Lateral sclerosis	8B60.4	Skin	6.49E-01	1.20E-02	1.12E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	8.40E-01	1.80E-01	5.79E-01
Liver cancer	2C12.0	Liver tissue	8.16E-01	-7.12E-02	-3.54E-01
Liver failure	DB99.7-DB99.8	Liver tissue	3.58E-01	-7.77E-02	-6.79E-01
Lung cancer	2C25	Lung tissue	4.81E-01	-9.40E-03	-6.25E-02
Lupus erythematosus	4A40	Whole blood	5.28E-02	-3.45E-02	-1.15E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	2.79E-01	5.51E-02	4.15E-01
Major depressive disorder	6A70-6A7Z	Whole blood	4.80E-01	2.95E-02	1.47E-01
Melanoma	2C30	Skin	1.60E-01	-6.39E-02	-2.34E-01
Multiple myeloma	2A83.1	Peripheral blood	6.17E-01	2.56E-02	1.81E-01
Multiple myeloma	2A83.1	Bone marrow	1.01E-04	-3.63E-01	-2.76E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	6.76E-01	5.50E-02	3.24E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	1.19E-01	-5.35E-02	-3.16E-01
Myelofibrosis	2A20.2	Whole blood	4.57E-03	1.05E-01	1.08E+00
Myocardial infarction	BA41-BA50	Peripheral blood	2.58E-02	1.55E-01	4.62E-01
Myopathy	8C70.6	Muscle tissue	2.79E-03	-2.03E-01	-1.85E+00
Neonatal sepsis	KA60	Whole blood	8.01E-01	-2.71E-02	-1.58E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.49E-01	6.48E-02	2.15E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	9.78E-01	9.54E-03	5.32E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.65E-02	1.24E-01	1.31E+00
Olive pollen allergy	CA08.00	Peripheral blood	2.96E-01	6.78E-02	5.48E-01
Oral cancer	2B6E	Oral tissue	4.08E-09	-4.67E-01	-1.73E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	9.37E-02	-5.88E-02	-3.77E-01
Osteoporosis	FB83.1	Bone marrow	2.39E-01	8.06E-02	5.74E-01
Ovarian cancer	2C73	Ovarian tissue	1.23E-01	-9.30E-02	-6.18E-01
Pancreatic cancer	2C10	Pancreas	2.03E-02	-1.77E-01	-7.52E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	3.94E-01	-5.32E-02	-4.28E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	8.21E-01	-3.45E-02	-3.48E-01
Pituitary cancer	2D12	Pituitary tissue	3.41E-02	1.14E-01	6.65E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	3.26E-01	7.80E-02	4.59E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	7.87E-01	-2.86E-03	-1.77E-02
Polycythemia vera	2A20.4	Whole blood	4.07E-08	9.50E-02	9.38E-01
Pompe disease	5C51.3	Biceps muscle	9.71E-02	-8.07E-02	-7.53E-01
Preterm birth	KA21.4Z	Myometrium	5.98E-01	3.09E-02	3.00E-01
Prostate cancer	2C82	Prostate	4.97E-01	1.18E-01	3.32E-01
Psoriasis	EA90	Skin	9.80E-02	-9.12E-02	-3.86E-01
Rectal cancer	2B92	Rectal colon tissue	3.04E-01	-8.92E-02	-4.64E-01
Renal cancer	2C90-2C91	Kidney	9.50E-01	5.15E-03	2.09E-02
Retinoblastoma	2D02.2	Uvea	2.34E-02	-8.85E-02	-7.08E-01
Rheumatoid arthritis	FA20	Synovial tissue	2.50E-02	-1.68E-01	-1.38E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.44E-01	-4.06E-02	-3.10E-01
Schizophrenia	6A20	Prefrontal cortex	6.53E-02	4.69E-02	2.33E-01
Schizophrenia	6A20	Superior temporal cortex	2.28E-01	6.02E-03	5.83E-02
Scleroderma	4A42.Z	Whole blood	4.03E-02	9.33E-02	8.49E-01
Seizure	8A60-8A6Z	Whole blood	8.70E-01	4.01E-02	2.37E-01
Sensitive skin	EK0Z	Skin	3.40E-01	2.94E-02	2.75E-01
Sepsis with septic shock	1G41	Whole blood	4.91E-03	2.31E-02	1.33E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.17E-02	2.94E-01	1.01E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	2.22E-01	5.46E-02	2.83E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	6.16E-01	4.11E-02	1.36E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.62E-02	-1.54E-01	-2.43E+00
Skin cancer	2C30-2C3Z	Skin	2.05E-05	-8.88E-02	-4.01E-01
Thrombocythemia	3B63	Whole blood	6.53E-04	7.85E-02	8.01E-01
Thrombocytopenia	3B64	Whole blood	6.06E-01	-9.05E-02	-2.28E-01
Thyroid cancer	2D10	Thyroid	4.42E-02	4.54E-02	2.51E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.39E-07	-2.62E-01	-2.34E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	9.93E-01	4.33E-02	4.20E-01
Type 2 diabetes	5A11	Liver tissue	2.26E-01	-4.62E-02	-5.81E-01
Ureter cancer	2C92	Urothelium	9.60E-01	1.42E-02	6.98E-02
Uterine cancer	2C78	Endometrium tissue	6.89E-01	2.58E-02	1.20E-01
Vitiligo	ED63.0	Skin	9.82E-01	-7.61E-03	-3.66E-02