Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEIVKZ8)

• DME Name: NADPH-dependent carbonyl reductase 3 (CBR3) DME Info
• Gene Name: CBR3

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	5.54E-07	1.99E-01	5.90E-01
Alopecia	ED70	Skin from scalp	2.49E-02	-1.26E-01	-2.50E-01
Alzheimer's disease	8A20	Entorhinal cortex	5.64E-02	1.12E-01	3.52E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.94E-01	2.39E-01	9.70E-01
Aortic stenosis	BB70	Calcified aortic valve	7.35E-01	-3.22E-01	-2.77E-01
Apnea	7A40	Hyperplastic tonsil	2.37E-01	-1.38E+00	-1.26E+00
Arthropathy	FA00-FA5Z	Peripheral blood	8.85E-01	-1.13E-01	-2.45E-01
Asthma	CA23	Nasal and bronchial airway	2.62E-05	9.83E-01	8.35E-01
Atopic dermatitis	EA80	Skin	1.17E-06	5.06E-01	1.86E+00
Autism	6A02	Whole blood	2.66E-01	4.81E-03	1.06E-02
Autoimmune uveitis	9A96	Peripheral monocyte	5.35E-02	-2.45E-01	-1.97E+00
Autosomal dominant monocytopenia	4B04	Whole blood	4.04E-01	1.49E-02	7.24E-02
Bacterial infection of gingival	1C1H	Gingival tissue	5.98E-21	-9.85E-01	-2.01E+00
Batten disease	5C56.1	Whole blood	4.96E-02	-3.24E-01	-8.70E-01
Behcet's disease	4A62	Peripheral blood	9.22E-01	-5.81E-02	-1.88E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	9.89E-01	-1.30E-02	-4.30E-02
Bladder cancer	2C94	Bladder tissue	6.30E-03	-4.44E-01	-1.53E+00
Breast cancer	2C60-2C6Z	Breast tissue	4.00E-09	-3.43E-01	-6.73E-01
Cardioembolic stroke	8B11.20	Whole blood	2.19E-05	-9.90E-01	-1.40E+00
Cervical cancer	2C77	Cervical tissue	1.94E-03	-2.97E-01	-7.50E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.83E-01	-1.52E-01	-2.89E-01
Chronic hepatitis C	1E51.1	Whole blood	6.04E-01	-5.34E-03	-2.52E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.83E-01	-2.15E-02	-5.00E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	4.64E-06	8.02E-01	1.05E+00
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	7.95E-02	5.30E-01	7.67E-01
Colon cancer	2B90	Colon tissue	3.20E-58	6.57E-01	1.67E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	2.94E-01	-1.66E-01	-4.35E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	1.63E-01	-1.89E-01	-2.87E-01
Endometriosis	GA10	Endometrium tissue	1.94E-02	-4.53E-01	-4.72E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.49E-01	2.04E-01	3.96E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.30E-04	-5.58E-01	-1.63E+00
Gastric cancer	2B72	Gastric tissue	3.11E-01	6.15E-01	6.52E-01
Glioblastopma	2A00.00	Nervous tissue	1.96E-24	4.07E-01	7.62E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	1.21E-01	-2.06E-01	-3.61E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.28E-01	4.06E-01	4.50E-01
Head and neck cancer	2D42	Head and neck tissue	4.41E-01	-1.65E-01	-1.41E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	9.62E-01	-1.14E-02	-2.33E-02
Huntington's disease	8A01.10	Whole blood	3.70E-01	-1.94E-01	-2.93E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	4.17E-02	5.19E-01	1.75E+00
Immunodeficiency	4A00-4A20	Peripheral blood	1.09E-02	-5.11E-01	-2.03E+00
Influenza	1E30	Whole blood	1.85E-01	-3.12E-01	-1.34E+00
Interstitial cystitis	GC00.3	Bladder tissue	9.44E-02	-2.05E-01	-7.22E-01
Intracranial aneurysm	8B01.0	Intracranial artery	4.22E-04	-8.22E-01	-3.26E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	5.46E-01	1.19E-02	3.25E-02
Ischemic stroke	8B11	Peripheral blood	7.71E-01	-5.05E-02	-9.43E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.09E-01	-1.12E-01	-1.63E-01
Lateral sclerosis	8B60.4	Skin	1.15E-01	1.80E-01	3.26E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	4.59E-02	3.84E-01	1.07E+00
Liver cancer	2C12.0	Liver tissue	1.36E-06	2.25E-01	6.28E-01
Liver failure	DB99.7-DB99.8	Liver tissue	4.00E-05	1.32E+00	6.49E+00
Lung cancer	2C25	Lung tissue	5.74E-32	3.47E-01	9.20E-01
Lupus erythematosus	4A40	Whole blood	8.76E-03	1.08E-02	1.59E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	1.25E-01	-1.72E-01	-5.69E-01
Major depressive disorder	6A70-6A7Z	Whole blood	6.99E-01	1.47E-01	2.55E-01
Melanoma	2C30	Skin	2.34E-01	-1.59E-01	-2.17E-01
Multiple myeloma	2A83.1	Peripheral blood	8.04E-01	6.23E-02	5.26E-02
Multiple myeloma	2A83.1	Bone marrow	5.73E-03	7.89E-02	6.61E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.51E-02	-3.05E-01	-1.06E+00
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	4.12E-12	-4.44E-01	-1.89E+00
Myelofibrosis	2A20.2	Whole blood	8.66E-01	1.96E-02	9.11E-02
Myocardial infarction	BA41-BA50	Peripheral blood	1.69E-02	-3.81E-01	-4.36E-01
Myopathy	8C70.6	Muscle tissue	7.42E-02	1.73E-01	3.76E-01
Neonatal sepsis	KA60	Whole blood	1.89E-21	-5.25E-01	-1.66E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	7.72E-05	5.53E-01	1.49E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.36E-02	-1.89E-01	-1.65E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.88E-01	-2.21E-01	-1.46E+00
Olive pollen allergy	CA08.00	Peripheral blood	1.23E-01	-8.71E-01	-1.47E+00
Oral cancer	2B6E	Oral tissue	1.80E-05	-1.26E+00	-1.14E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	1.37E-01	2.07E-01	2.96E-01
Osteoporosis	FB83.1	Bone marrow	1.10E-03	-9.24E-01	-3.15E+00
Ovarian cancer	2C73	Ovarian tissue	3.34E-03	-8.04E-01	-1.50E+00
Pancreatic cancer	2C10	Pancreas	2.11E-05	4.14E-01	1.33E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	1.21E-01	-2.08E-01	-5.75E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	4.84E-02	-2.68E-01	-7.80E-01
Pituitary cancer	2D12	Pituitary tissue	3.41E-01	8.39E-02	2.33E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.31E-01	8.33E-02	2.40E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	8.67E-01	-3.90E-02	-1.83E-01
Polycythemia vera	2A20.4	Whole blood	1.66E-01	1.68E-02	7.83E-02
Pompe disease	5C51.3	Biceps muscle	7.59E-01	-1.53E-02	-3.93E-02
Preterm birth	KA21.4Z	Myometrium	1.84E-01	-4.28E-01	-1.30E+00
Prostate cancer	2C82	Prostate	7.27E-04	1.01E+00	9.72E-01
Psoriasis	EA90	Skin	1.94E-21	4.76E-01	1.28E+00
Rectal cancer	2B92	Rectal colon tissue	8.56E-04	3.12E-01	1.86E+00
Renal cancer	2C90-2C91	Kidney	1.45E-05	7.15E-01	1.77E+00
Retinoblastoma	2D02.2	Uvea	5.51E-10	3.05E+00	1.01E+01
Rheumatoid arthritis	FA20	Synovial tissue	2.24E-02	5.57E-01	8.17E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	4.86E-01	-8.84E-02	-1.71E-01
Schizophrenia	6A20	Prefrontal cortex	9.12E-01	3.16E-02	1.03E-01
Schizophrenia	6A20	Superior temporal cortex	6.65E-01	1.37E-01	5.05E-01
Scleroderma	4A42.Z	Whole blood	5.75E-02	4.07E-01	8.63E-01
Seizure	8A60-8A6Z	Whole blood	6.84E-03	4.96E-01	1.36E+00
Sensitive skin	EK0Z	Skin	9.42E-01	5.02E-02	2.64E-01
Sepsis with septic shock	1G41	Whole blood	4.31E-31	-4.70E-01	-1.36E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.97E-01	-1.70E-01	-4.49E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.11E-01	-6.05E-03	-3.26E-02
Simpson golabi behmel syndrome	LD2C	Adipose tissue	6.47E-01	-8.11E-01	-5.83E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.91E-01	1.18E-01	3.68E-01
Skin cancer	2C30-2C3Z	Skin	1.55E-01	-2.61E-02	-6.13E-02
Thrombocythemia	3B63	Whole blood	2.93E-01	7.47E-02	3.47E-01
Thrombocytopenia	3B64	Whole blood	4.65E-01	6.54E-01	8.94E-01
Thyroid cancer	2D10	Thyroid	1.23E-19	5.58E-01	1.70E+00
Tibial muscular dystrophy	8C75	Muscle tissue	1.20E-05	6.97E-01	2.22E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	7.76E-01	2.53E-01	7.91E-01
Type 2 diabetes	5A11	Liver tissue	2.03E-01	-7.34E-02	-3.03E-01
Ureter cancer	2C92	Urothelium	7.57E-01	-5.93E-03	-3.46E-02
Uterine cancer	2C78	Endometrium tissue	1.14E-02	-2.70E-01	-2.42E-01
Vitiligo	ED63.0	Skin	7.17E-01	-3.91E-02	-1.60E-01