Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEKF1OH)

• DME Name: Methionine adenosyltransferase II beta (MAT2B) DME Info
• Gene Name: MAT2B

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.10E-25	-3.52E-01	-1.32E+00
Alopecia	ED70	Skin from scalp	2.20E-01	2.91E-04	1.15E-03
Alzheimer's disease	8A20	Entorhinal cortex	3.65E-03	-9.28E-02	-3.24E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	6.23E-01	4.28E-03	1.31E-02
Aortic stenosis	BB70	Calcified aortic valve	7.27E-01	-1.34E-01	-1.99E-01
Apnea	7A40	Hyperplastic tonsil	3.27E-02	3.39E-01	2.37E+00
Arthropathy	FA00-FA5Z	Peripheral blood	7.76E-01	5.70E-02	3.75E-01
Asthma	CA23	Nasal and bronchial airway	1.99E-03	-1.58E-01	-1.84E-01
Atopic dermatitis	EA80	Skin	2.31E-02	-2.19E-01	-1.04E+00
Autism	6A02	Whole blood	6.95E-01	-6.70E-03	-2.43E-02
Autoimmune uveitis	9A96	Peripheral monocyte	4.56E-01	-6.76E-02	-1.57E-01
Autosomal dominant monocytopenia	4B04	Whole blood	2.37E-01	-7.20E-01	-1.39E+00
Bacterial infection of gingival	1C1H	Gingival tissue	2.77E-02	8.35E-02	3.49E-01
Batten disease	5C56.1	Whole blood	6.02E-02	-1.70E-01	-1.16E+00
Behcet's disease	4A62	Peripheral blood	5.58E-01	9.67E-02	2.89E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	4.56E-01	-9.65E-02	-3.56E-01
Bladder cancer	2C94	Bladder tissue	2.69E-02	-3.71E-01	-1.15E+00
Breast cancer	2C60-2C6Z	Breast tissue	3.37E-35	-2.25E-01	-9.21E-01
Cardioembolic stroke	8B11.20	Whole blood	2.76E-08	4.53E-01	2.21E+00
Cervical cancer	2C77	Cervical tissue	4.80E-01	6.17E-02	2.69E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.01E-01	1.56E-01	8.08E-01
Chronic hepatitis C	1E51.1	Whole blood	1.38E-01	-8.52E-02	-4.69E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.40E-01	4.04E-02	1.34E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	9.13E-02	-1.15E-01	-4.40E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	9.35E-01	-7.51E-02	-4.34E-01
Colon cancer	2B90	Colon tissue	1.13E-17	-2.80E-01	-8.11E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.12E-01	1.30E-01	3.06E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.66E-01	3.24E-02	1.99E-01
Endometriosis	GA10	Endometrium tissue	2.34E-01	2.59E-01	5.21E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	2.59E-02	-1.59E-01	-8.75E-01
Familial hypercholesterolemia	5C80.00	Whole blood	4.81E-05	-4.53E-01	-2.23E+00
Gastric cancer	2B72	Gastric tissue	7.70E-01	-5.36E-02	-1.62E-01
Glioblastopma	2A00.00	Nervous tissue	3.64E-45	-2.98E-01	-8.63E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	7.07E-01	1.48E-01	3.87E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.16E-01	-5.03E-02	-2.06E-01
Head and neck cancer	2D42	Head and neck tissue	1.34E-05	-2.16E-01	-7.09E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	2.06E-01	-1.77E-01	-6.97E-01
Huntington's disease	8A01.10	Whole blood	6.51E-01	-6.04E-02	-3.51E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	5.83E-01	-4.20E-02	-1.73E-01
Immunodeficiency	4A00-4A20	Peripheral blood	2.42E-01	-1.36E-01	-9.27E-01
Influenza	1E30	Whole blood	3.07E-01	1.17E-01	7.47E-01
Interstitial cystitis	GC00.3	Bladder tissue	4.24E-01	-1.02E-02	-7.04E-02
Intracranial aneurysm	8B01.0	Intracranial artery	8.58E-01	4.96E-02	3.18E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.61E-02	-1.98E-01	-6.05E-01
Ischemic stroke	8B11	Peripheral blood	4.67E-01	-1.35E-01	-3.38E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.56E-01	2.13E-02	5.42E-02
Lateral sclerosis	8B60.4	Skin	3.39E-01	2.63E-01	1.13E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	8.46E-02	-2.97E-01	-8.35E-01
Liver cancer	2C12.0	Liver tissue	9.30E-03	-1.19E-01	-3.14E-01
Liver failure	DB99.7-DB99.8	Liver tissue	8.02E-03	-2.37E-01	-1.15E+00
Lung cancer	2C25	Lung tissue	9.91E-07	-1.92E-01	-5.82E-01
Lupus erythematosus	4A40	Whole blood	7.90E-06	1.05E+00	1.44E+00
Major depressive disorder	6A70-6A7Z	Hippocampus	8.17E-01	-1.04E-01	-4.04E-01
Major depressive disorder	6A70-6A7Z	Whole blood	7.46E-01	7.84E-03	3.69E-02
Melanoma	2C30	Skin	2.74E-01	1.39E-02	3.70E-02
Multiple myeloma	2A83.1	Peripheral blood	1.59E-01	9.03E-02	6.54E-01
Multiple myeloma	2A83.1	Bone marrow	2.11E-01	-1.15E-01	-3.86E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.52E-01	-6.46E-02	-3.54E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.58E-02	-6.59E-02	-3.93E-01
Myelofibrosis	2A20.2	Whole blood	2.93E-04	-1.67E-01	-1.19E+00
Myocardial infarction	BA41-BA50	Peripheral blood	7.43E-04	-4.79E-01	-6.02E-01
Myopathy	8C70.6	Muscle tissue	1.95E-01	2.62E-01	1.06E+00
Neonatal sepsis	KA60	Whole blood	1.31E-01	-7.78E-02	-2.51E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	5.70E-01	4.09E-02	2.27E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	6.74E-01	-2.24E-02	-9.20E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.57E-01	-1.62E-01	-5.44E-01
Olive pollen allergy	CA08.00	Peripheral blood	4.17E-01	1.34E-01	6.33E-01
Oral cancer	2B6E	Oral tissue	4.69E-02	9.59E-02	3.37E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	2.02E-01	8.43E-02	4.32E-01
Osteoporosis	FB83.1	Bone marrow	4.47E-03	-4.14E-01	-2.19E+00
Ovarian cancer	2C73	Ovarian tissue	9.07E-01	-1.06E-01	-4.01E-01
Pancreatic cancer	2C10	Pancreas	2.23E-03	3.21E-01	1.31E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	9.24E-01	-7.99E-02	-2.98E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	3.39E-01	-1.00E-01	-5.14E-01
Pituitary cancer	2D12	Pituitary tissue	9.80E-01	-1.02E-01	-7.04E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.84E-02	-1.71E-01	-1.34E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	3.97E-01	-6.35E-02	-5.49E-01
Polycythemia vera	2A20.4	Whole blood	1.65E-06	-2.07E-01	-1.29E+00
Pompe disease	5C51.3	Biceps muscle	5.54E-04	-4.36E-01	-3.10E+00
Preterm birth	KA21.4Z	Myometrium	8.34E-01	1.37E-01	3.89E-01
Prostate cancer	2C82	Prostate	3.53E-03	6.60E-01	1.32E+00
Psoriasis	EA90	Skin	1.67E-03	3.74E-02	1.10E-01
Rectal cancer	2B92	Rectal colon tissue	2.52E-01	-4.21E-02	-1.68E-01
Renal cancer	2C90-2C91	Kidney	3.50E-01	1.06E-01	4.15E-01
Retinoblastoma	2D02.2	Uvea	9.48E-03	-3.00E-01	-1.21E+00
Rheumatoid arthritis	FA20	Synovial tissue	2.59E-02	3.48E-01	1.57E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	1.30E-01	3.39E-02	2.33E-01
Schizophrenia	6A20	Prefrontal cortex	6.18E-01	-9.94E-03	-2.44E-02
Schizophrenia	6A20	Superior temporal cortex	6.34E-01	-2.44E-02	-1.17E-01
Scleroderma	4A42.Z	Whole blood	5.45E-05	1.49E-01	2.07E+00
Seizure	8A60-8A6Z	Whole blood	3.91E-01	6.70E-03	4.30E-02
Sensitive skin	EK0Z	Skin	7.00E-01	-1.23E-02	-7.04E-02
Sepsis with septic shock	1G41	Whole blood	2.67E-25	-2.99E-01	-1.08E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	9.92E-02	4.06E-01	1.17E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.81E-01	2.09E-01	6.37E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	2.45E-01	-3.63E-02	-3.41E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.57E-03	3.14E-01	4.74E+00
Skin cancer	2C30-2C3Z	Skin	1.81E-05	1.39E-01	4.04E-01
Thrombocythemia	3B63	Whole blood	7.02E-08	-2.39E-01	-1.67E+00
Thrombocytopenia	3B64	Whole blood	2.95E-01	-3.86E-01	-5.89E-01
Thyroid cancer	2D10	Thyroid	4.40E-04	-1.42E-01	-4.78E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.85E-02	-1.69E-01	-6.50E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.59E-02	-5.31E-01	-2.14E+00
Type 2 diabetes	5A11	Liver tissue	5.87E-01	6.91E-02	4.72E-01
Ureter cancer	2C92	Urothelium	6.79E-01	-1.56E-01	-3.71E-01
Uterine cancer	2C78	Endometrium tissue	1.37E-04	-1.71E-01	-4.93E-01
Vitiligo	ED63.0	Skin	6.89E-01	4.84E-02	4.92E-01