Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEKN1H4)

• DME Name: Retinal dehydrogenase 2 (ALDH1A2) DME Info
• Gene Name: ALDH1A2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	8.74E-02	6.39E-02	2.66E-01
Alopecia	ED70	Skin from scalp	1.03E-02	-6.27E-02	-3.79E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.36E-02	-2.80E-02	-1.35E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	3.80E-01	1.08E-01	1.96E-01
Aortic stenosis	BB70	Calcified aortic valve	4.53E-01	2.10E-02	3.08E-02
Apnea	7A40	Hyperplastic tonsil	1.31E-02	-2.43E-01	-1.71E+00
Arthropathy	FA00-FA5Z	Peripheral blood	3.13E-01	8.22E-02	4.05E-01
Asthma	CA23	Nasal and bronchial airway	3.88E-01	-1.43E-01	-3.82E-01
Atopic dermatitis	EA80	Skin	1.54E-06	-2.04E-01	-1.49E+00
Autism	6A02	Whole blood	5.82E-01	8.98E-02	3.27E-01
Autoimmune uveitis	9A96	Peripheral monocyte	2.52E-02	-1.84E-01	-8.03E-01
Autosomal dominant monocytopenia	4B04	Whole blood	6.27E-01	0.00E+00	0.00E+00
Bacterial infection of gingival	1C1H	Gingival tissue	3.55E-05	1.19E-01	6.19E-01
Batten disease	5C56.1	Whole blood	5.55E-01	7.46E-02	7.70E-01
Behcet's disease	4A62	Peripheral blood	9.00E-01	1.54E-02	8.09E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.95E-01	-4.53E-02	-1.91E-01
Bladder cancer	2C94	Bladder tissue	2.11E-02	-2.35E-01	-1.83E+00
Breast cancer	2C60-2C6Z	Breast tissue	7.47E-14	-1.56E-01	-3.31E-01
Cardioembolic stroke	8B11.20	Whole blood	7.97E-01	-2.99E-02	-1.59E-01
Cervical cancer	2C77	Cervical tissue	9.16E-01	-1.94E-02	-8.90E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	5.20E-01	-2.27E-02	-9.76E-02
Chronic hepatitis C	1E51.1	Whole blood	2.95E-01	4.81E-02	2.63E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	8.71E-01	3.07E-02	1.16E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.10E-03	1.23E-01	4.31E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	3.20E-02	-3.25E-01	-1.14E+00
Colon cancer	2B90	Colon tissue	7.94E-12	-1.92E-01	-6.20E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.79E-01	-2.96E-01	-1.00E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	6.68E-01	4.32E-02	2.32E-01
Endometriosis	GA10	Endometrium tissue	1.19E-01	-6.26E-01	-5.19E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.39E-01	2.07E-02	1.29E-01
Familial hypercholesterolemia	5C80.00	Whole blood	9.42E-03	2.07E-01	1.13E+00
Gastric cancer	2B72	Gastric tissue	1.95E-01	-1.64E-01	-1.43E+00
Glioblastopma	2A00.00	Nervous tissue	4.84E-99	-5.02E-01	-1.56E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	2.48E-01	-1.03E-01	-1.77E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.95E-01	-4.20E-01	-9.69E-01
Head and neck cancer	2D42	Head and neck tissue	1.90E-10	-1.82E-01	-8.50E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	9.20E-02	-7.92E-02	-3.74E-01
Huntington's disease	8A01.10	Whole blood	3.07E-02	2.58E-01	1.42E+00
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	8.19E-01	1.23E-01	4.50E-01
Immunodeficiency	4A00-4A20	Peripheral blood	2.37E-01	5.16E-02	3.28E-01
Influenza	1E30	Whole blood	1.26E-01	3.55E-01	1.25E+00
Interstitial cystitis	GC00.3	Bladder tissue	3.10E-02	-5.70E-01	-1.34E+00
Intracranial aneurysm	8B01.0	Intracranial artery	7.62E-01	-8.35E-02	-3.64E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	6.08E-01	6.29E-02	2.49E-01
Ischemic stroke	8B11	Peripheral blood	6.85E-01	5.38E-02	2.61E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.01E-02	7.65E-02	3.54E-01
Lateral sclerosis	8B60.4	Skin	6.35E-01	-5.77E-02	-8.86E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	6.22E-01	7.95E-02	2.01E-01
Liver cancer	2C12.0	Liver tissue	1.61E-01	-1.64E-01	-4.43E-01
Liver failure	DB99.7-DB99.8	Liver tissue	4.96E-01	3.52E-02	2.99E-01
Lung cancer	2C25	Lung tissue	2.57E-33	-4.16E-01	-1.27E+00
Lupus erythematosus	4A40	Whole blood	1.49E-02	-4.29E-02	-1.12E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	1.87E-01	-2.33E-02	-1.01E-01
Major depressive disorder	6A70-6A7Z	Whole blood	9.21E-02	7.67E-02	3.58E-01
Melanoma	2C30	Skin	6.19E-01	-2.18E-01	-4.34E-01
Multiple myeloma	2A83.1	Peripheral blood	1.33E-01	1.19E-01	5.72E-01
Multiple myeloma	2A83.1	Bone marrow	8.95E-01	1.43E-01	3.41E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.01E-01	-6.11E-03	-2.28E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	3.88E-03	1.35E-01	6.20E-01
Myelofibrosis	2A20.2	Whole blood	7.77E-01	-5.31E-02	-3.17E-01
Myocardial infarction	BA41-BA50	Peripheral blood	9.96E-01	2.36E-02	7.70E-02
Myopathy	8C70.6	Muscle tissue	5.75E-01	1.13E-01	4.05E-01
Neonatal sepsis	KA60	Whole blood	7.84E-02	9.36E-02	2.65E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	9.77E-05	-6.99E-01	-1.91E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.86E-01	4.01E-02	1.95E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	9.86E-02	-1.12E-01	-5.41E-01
Olive pollen allergy	CA08.00	Peripheral blood	4.15E-01	1.84E-01	6.10E-01
Oral cancer	2B6E	Oral tissue	1.15E-09	-4.65E-01	-1.57E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	6.08E-02	-1.66E-01	-8.51E-01
Osteoporosis	FB83.1	Bone marrow	2.04E-02	3.80E-01	1.94E+00
Ovarian cancer	2C73	Ovarian tissue	3.85E-02	-5.54E-01	-8.31E-01
Pancreatic cancer	2C10	Pancreas	4.34E-01	2.16E-02	7.83E-02
Parkinson's disease	8A00.0	Substantia nigra tissue	6.03E-01	-8.17E-02	-2.69E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	4.64E-01	5.82E-03	2.72E-02
Pituitary cancer	2D12	Pituitary tissue	1.78E-02	-7.89E-01	-1.62E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	8.82E-03	-9.22E-01	-2.00E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.52E-02	-7.89E-02	-5.37E-01
Polycythemia vera	2A20.4	Whole blood	3.45E-06	1.01E-01	5.58E-01
Pompe disease	5C51.3	Biceps muscle	2.24E-01	-1.47E-01	-6.77E-01
Preterm birth	KA21.4Z	Myometrium	7.41E-01	2.64E-01	4.80E-01
Prostate cancer	2C82	Prostate	7.25E-02	-2.14E-01	-3.49E-01
Psoriasis	EA90	Skin	6.39E-07	-1.54E-01	-4.54E-01
Rectal cancer	2B92	Rectal colon tissue	7.85E-01	-6.96E-02	-1.86E-01
Renal cancer	2C90-2C91	Kidney	5.12E-04	-7.37E-01	-1.52E+00
Retinoblastoma	2D02.2	Uvea	6.19E-05	-6.31E-01	-3.54E+00
Rheumatoid arthritis	FA20	Synovial tissue	6.98E-03	2.54E-01	9.13E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	8.33E-01	-1.33E-02	-1.05E-01
Schizophrenia	6A20	Prefrontal cortex	7.44E-01	-3.88E-02	-1.09E-01
Schizophrenia	6A20	Superior temporal cortex	7.11E-01	0.00E+00	0.00E+00
Scleroderma	4A42.Z	Whole blood	6.81E-02	-7.01E-02	-6.25E-01
Seizure	8A60-8A6Z	Whole blood	4.90E-01	-4.59E-02	-1.81E-01
Sensitive skin	EK0Z	Skin	2.33E-01	-1.09E-01	-5.74E-01
Sepsis with septic shock	1G41	Whole blood	9.87E-01	-3.41E-03	-9.65E-03
Shwachman-Diamond syndrome	3A70.0	Bone marrow	9.97E-01	-3.09E-02	-1.23E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.24E-01	4.24E-01	1.11E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	1.12E-01	1.14E-01	1.28E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	5.99E-01	-2.03E-01	-1.31E+00
Skin cancer	2C30-2C3Z	Skin	7.06E-18	-4.40E-01	-9.08E-01
Thrombocythemia	3B63	Whole blood	1.03E-02	1.05E-01	6.14E-01
Thrombocytopenia	3B64	Whole blood	7.27E-01	3.83E-02	1.49E-01
Thyroid cancer	2D10	Thyroid	1.39E-04	-9.51E-02	-3.43E-01
Tibial muscular dystrophy	8C75	Muscle tissue	3.45E-02	-2.90E-01	-6.38E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.97E-02	-1.78E-01	-1.56E+01
Type 2 diabetes	5A11	Liver tissue	2.73E-02	-1.02E-01	-6.85E-01
Ureter cancer	2C92	Urothelium	6.57E-01	-1.24E-01	-2.90E-01
Uterine cancer	2C78	Endometrium tissue	9.35E-19	-9.31E-01	-1.01E+00
Vitiligo	ED63.0	Skin	4.72E-01	-1.02E-01	-4.56E-01