Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEPE0RD)

• DME Name: Steroid 11-beta-hydroxylase (CYP11B1) DME Info
• Gene Name: CYP11B1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.40E-05	5.58E-02	4.46E-01
Alopecia	ED70	Skin from scalp	2.16E-01	1.74E-02	1.19E-01
Alzheimer's disease	8A20	Entorhinal cortex	9.12E-01	-8.48E-04	-7.66E-03
Ankylosing spondylitis	FA92.0	Pheripheral blood	6.78E-01	3.63E-02	6.33E-01
Aortic stenosis	BB70	Calcified aortic valve	6.80E-01	9.28E-02	3.40E-01
Apnea	7A40	Hyperplastic tonsil	6.45E-01	2.06E-03	1.35E-02
Arthropathy	FA00-FA5Z	Peripheral blood	3.15E-01	6.02E-02	6.30E-01
Asthma	CA23	Nasal and bronchial airway	3.74E-02	-5.60E-02	-2.08E-01
Atopic dermatitis	EA80	Skin	8.06E-07	1.01E-01	1.25E+00
Autism	6A02	Whole blood	2.07E-01	-2.33E-03	-1.53E-02
Autoimmune uveitis	9A96	Peripheral monocyte	9.60E-03	-1.90E-01	-2.37E+00
Autosomal dominant monocytopenia	4B04	Whole blood	4.59E-01	-6.23E-02	-4.51E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.25E-01	3.88E-02	2.39E-01
Batten disease	5C56.1	Whole blood	3.90E-01	1.40E-02	1.60E-01
Behcet's disease	4A62	Peripheral blood	2.69E-01	5.23E-02	6.33E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.76E-01	-2.95E-02	-2.59E-01
Bladder cancer	2C94	Bladder tissue	1.19E-08	4.43E-01	4.33E+00
Breast cancer	2C60-2C6Z	Breast tissue	4.31E-04	-2.65E-02	-1.28E-01
Cardioembolic stroke	8B11.20	Whole blood	1.63E-02	6.61E-02	5.06E-01
Cervical cancer	2C77	Cervical tissue	5.07E-01	-2.42E-02	-1.17E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	9.56E-01	-2.62E-02	-1.46E-01
Chronic hepatitis C	1E51.1	Whole blood	7.02E-01	1.13E-02	6.56E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.55E-02	7.20E-02	5.54E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	7.89E-01	-3.53E-03	-2.90E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	2.90E-01	4.99E-02	4.99E-01
Colon cancer	2B90	Colon tissue	5.95E-01	8.29E-03	5.20E-02
Coronary artery disease	BA80-BA8Z	Peripheral blood	2.16E-01	-6.62E-02	-6.01E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	6.59E-01	2.39E-02	2.58E-01
Endometriosis	GA10	Endometrium tissue	7.83E-01	1.92E-02	1.40E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.28E-01	7.50E-03	7.49E-02
Familial hypercholesterolemia	5C80.00	Whole blood	6.10E-01	-2.97E-02	-2.14E-01
Gastric cancer	2B72	Gastric tissue	7.49E-01	4.50E-02	2.56E-01
Glioblastopma	2A00.00	Nervous tissue	1.33E-05	7.19E-02	3.96E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	5.04E-01	-7.49E-02	-6.91E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	3.25E-07	-6.04E-01	-3.90E+00
Head and neck cancer	2D42	Head and neck tissue	1.86E-02	5.56E-02	4.01E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.11E-01	-9.34E-02	-5.99E-01
Huntington's disease	8A01.10	Whole blood	3.96E-01	3.95E-02	2.98E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.76E-01	-7.27E-02	-4.21E-01
Immunodeficiency	4A00-4A20	Peripheral blood	8.46E-01	1.94E-02	2.01E-01
Influenza	1E30	Whole blood	1.46E-01	1.02E-01	1.13E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.37E-01	6.61E-02	1.07E+00
Intracranial aneurysm	8B01.0	Intracranial artery	6.51E-01	-8.58E-03	-5.01E-02
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.62E-01	6.73E-02	3.22E-01
Ischemic stroke	8B11	Peripheral blood	6.80E-02	1.15E-01	1.33E+00
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.91E-04	7.60E-02	4.10E-01
Lateral sclerosis	8B60.4	Skin	9.15E-01	3.38E-02	2.23E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	7.95E-01	4.03E-02	2.04E-01
Liver cancer	2C12.0	Liver tissue	1.31E-01	-5.48E-02	-3.41E-01
Liver failure	DB99.7-DB99.8	Liver tissue	6.40E-02	6.03E-02	4.57E-01
Lung cancer	2C25	Lung tissue	2.69E-08	5.74E-02	4.68E-01
Lupus erythematosus	4A40	Whole blood	1.45E-03	-1.30E-01	-4.76E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	5.19E-01	5.57E-03	4.94E-02
Major depressive disorder	6A70-6A7Z	Whole blood	6.49E-01	-7.39E-03	-4.07E-02
Melanoma	2C30	Skin	6.02E-01	5.74E-02	1.73E-01
Multiple myeloma	2A83.1	Peripheral blood	3.10E-01	-1.23E-02	-1.01E-01
Multiple myeloma	2A83.1	Bone marrow	2.24E-06	-2.40E-01	-4.68E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	8.42E-01	2.46E-02	1.12E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.22E-01	-2.28E-02	-2.28E-01
Myelofibrosis	2A20.2	Whole blood	4.97E-03	8.04E-02	7.89E-01
Myocardial infarction	BA41-BA50	Peripheral blood	5.21E-02	1.91E-01	5.55E-01
Myopathy	8C70.6	Muscle tissue	1.26E-01	-1.40E-01	-6.84E-01
Neonatal sepsis	KA60	Whole blood	9.09E-04	-5.45E-02	-3.62E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.25E-02	-3.81E-01	-1.19E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	3.05E-01	-4.09E-02	-6.74E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.33E-01	4.19E-03	8.52E-02
Olive pollen allergy	CA08.00	Peripheral blood	5.22E-02	3.55E-02	6.73E-01
Oral cancer	2B6E	Oral tissue	3.02E-04	-1.65E-01	-9.32E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	9.12E-01	-4.23E-02	-2.15E-01
Osteoporosis	FB83.1	Bone marrow	3.62E-01	4.55E-02	1.26E+00
Ovarian cancer	2C73	Ovarian tissue	1.27E-01	-1.05E-01	-2.11E-01
Pancreatic cancer	2C10	Pancreas	2.04E-02	-1.26E-01	-7.75E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	5.01E-01	9.11E-03	1.80E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.97E-02	-8.33E-02	-1.16E+00
Pituitary cancer	2D12	Pituitary tissue	7.30E-01	1.32E-01	1.76E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.25E-01	8.15E-02	8.48E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.23E-01	1.69E-03	2.29E-02
Polycythemia vera	2A20.4	Whole blood	6.92E-05	8.36E-02	7.43E-01
Pompe disease	5C51.3	Biceps muscle	1.47E-01	-3.48E-02	-2.74E-01
Preterm birth	KA21.4Z	Myometrium	7.35E-01	8.18E-02	1.47E+00
Prostate cancer	2C82	Prostate	2.68E-02	-3.49E-01	-7.73E-01
Psoriasis	EA90	Skin	2.86E-03	-5.13E-02	-3.02E-01
Rectal cancer	2B92	Rectal colon tissue	9.21E-02	-1.66E-01	-1.00E+00
Renal cancer	2C90-2C91	Kidney	2.14E-01	-3.63E-02	-2.22E-01
Retinoblastoma	2D02.2	Uvea	1.55E-06	-2.52E-01	-3.89E+00
Rheumatoid arthritis	FA20	Synovial tissue	6.11E-01	-1.05E-03	-4.33E-03
Rhinovirus infection	CA42.1	Nasal epithelium tissue	7.38E-01	2.47E-02	2.61E-01
Schizophrenia	6A20	Prefrontal cortex	1.41E-01	2.95E-02	1.67E-01
Schizophrenia	6A20	Superior temporal cortex	1.35E-01	-7.29E-02	-9.24E-01
Scleroderma	4A42.Z	Whole blood	3.62E-01	9.37E-03	1.14E-01
Seizure	8A60-8A6Z	Whole blood	3.60E-01	-2.21E-02	-1.67E-01
Sensitive skin	EK0Z	Skin	2.20E-01	-9.58E-02	-1.23E+00
Sepsis with septic shock	1G41	Whole blood	7.96E-03	7.35E-02	4.23E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.64E-01	3.15E-01	1.03E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.66E-01	7.70E-02	6.58E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	7.87E-01	1.07E-01	1.40E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.36E-01	-1.80E-01	-8.77E-01
Skin cancer	2C30-2C3Z	Skin	2.83E-01	1.95E-02	8.03E-02
Thrombocythemia	3B63	Whole blood	3.76E-02	2.38E-02	2.54E-01
Thrombocytopenia	3B64	Whole blood	1.89E-01	1.15E-01	1.02E+00
Thyroid cancer	2D10	Thyroid	2.06E-03	4.64E-02	2.93E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.81E-01	-8.16E-02	-4.60E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	9.39E-02	1.86E-01	1.77E+00
Type 2 diabetes	5A11	Liver tissue	2.70E-01	9.19E-02	9.75E-01
Ureter cancer	2C92	Urothelium	7.30E-01	-1.55E-02	-1.07E-01
Uterine cancer	2C78	Endometrium tissue	4.27E-08	-1.03E-01	-5.72E-01
Vitiligo	ED63.0	Skin	5.48E-01	-3.51E-02	-3.11E-01