Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEPVE0M)

• DME Name: Tryptophanyl-tRNA synthetase cytoplasmic (WARS1) DME Info
• Gene Name: WARS1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	7.96E-03	-2.01E-01	-4.50E-01
Alopecia	ED70	Skin from scalp	9.78E-03	6.08E-02	2.50E-01
Alzheimer's disease	8A20	Entorhinal cortex	5.98E-07	-3.42E-01	-7.39E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.42E-01	-1.17E-01	-3.01E-01
Aortic stenosis	BB70	Calcified aortic valve	9.16E-01	-7.86E-02	-7.72E-02
Apnea	7A40	Hyperplastic tonsil	6.59E-03	4.80E-01	1.88E+00
Arthropathy	FA00-FA5Z	Peripheral blood	4.53E-01	1.31E-01	4.06E-01
Asthma	CA23	Nasal and bronchial airway	7.47E-03	1.51E-01	1.75E-01
Atopic dermatitis	EA80	Skin	2.23E-02	8.46E-02	5.43E-01
Autism	6A02	Whole blood	9.78E-01	8.01E-02	1.57E-01
Autoimmune uveitis	9A96	Peripheral monocyte	4.91E-01	1.34E-01	2.81E-01
Autosomal dominant monocytopenia	4B04	Whole blood	7.15E-02	7.34E-01	1.15E+00
Bacterial infection of gingival	1C1H	Gingival tissue	1.06E-11	6.59E-01	1.27E+00
Batten disease	5C56.1	Whole blood	6.61E-01	1.37E-03	2.38E-03
Behcet's disease	4A62	Peripheral blood	1.74E-01	3.54E-01	9.64E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	4.07E-02	-8.31E-02	-3.27E-01
Bladder cancer	2C94	Bladder tissue	2.72E-01	-7.70E-02	-4.02E-01
Breast cancer	2C60-2C6Z	Breast tissue	1.38E-22	2.70E-01	5.08E-01
Cardioembolic stroke	8B11.20	Whole blood	8.15E-02	1.66E-01	5.22E-01
Cervical cancer	2C77	Cervical tissue	2.61E-08	4.13E-01	1.24E+00
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	2.78E-01	-2.11E-02	-4.19E-02
Chronic hepatitis C	1E51.1	Whole blood	6.43E-01	-2.53E-01	-2.37E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.57E-01	1.16E-01	2.71E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	6.77E-02	1.86E-01	3.36E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	2.89E-01	6.96E-02	2.33E-01
Colon cancer	2B90	Colon tissue	3.05E-27	5.33E-01	1.10E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.66E-01	-3.89E-01	-3.86E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.61E-01	-4.70E-01	-7.13E-01
Endometriosis	GA10	Endometrium tissue	4.56E-03	-2.77E-01	-3.81E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.12E-02	-3.93E-01	-8.57E-01
Familial hypercholesterolemia	5C80.00	Whole blood	4.21E-07	1.17E+00	1.36E+00
Gastric cancer	2B72	Gastric tissue	5.06E-01	9.35E-01	7.09E-01
Glioblastopma	2A00.00	Nervous tissue	4.34E-01	-2.17E-01	-3.77E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	2.67E-01	-7.54E-01	-1.50E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.59E-03	1.42E+00	1.67E+00
Head and neck cancer	2D42	Head and neck tissue	8.24E-11	9.63E-01	8.89E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	5.59E-02	2.86E-01	5.86E-01
Huntington's disease	8A01.10	Whole blood	5.69E-01	-4.16E-02	-3.80E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	8.50E-01	1.37E-01	8.39E-01
Immunodeficiency	4A00-4A20	Peripheral blood	1.81E-04	5.31E-01	3.10E+00
Influenza	1E30	Whole blood	1.37E-01	1.52E+00	1.48E+00
Interstitial cystitis	GC00.3	Bladder tissue	4.22E-05	1.73E+00	7.64E+00
Intracranial aneurysm	8B01.0	Intracranial artery	3.51E-02	4.88E-01	1.13E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	7.94E-01	-1.03E-01	-1.88E-01
Ischemic stroke	8B11	Peripheral blood	1.36E-01	-1.55E-01	-4.32E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	8.77E-05	-3.92E-01	-5.07E-01
Lateral sclerosis	8B60.4	Skin	9.77E-01	-9.31E-02	-2.38E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	8.30E-01	4.79E-01	6.05E-01
Liver cancer	2C12.0	Liver tissue	9.12E-02	9.66E-02	1.91E-01
Liver failure	DB99.7-DB99.8	Liver tissue	8.25E-05	9.68E-01	3.18E+00
Lung cancer	2C25	Lung tissue	2.27E-52	-8.08E-01	-1.68E+00
Lupus erythematosus	4A40	Whole blood	6.78E-02	2.62E-01	3.07E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	3.18E-01	5.77E-02	2.97E-01
Major depressive disorder	6A70-6A7Z	Whole blood	5.80E-01	9.90E-03	1.74E-02
Melanoma	2C30	Skin	7.45E-06	1.09E+00	1.30E+00
Multiple myeloma	2A83.1	Peripheral blood	4.76E-01	-1.00E+00	-1.03E+00
Multiple myeloma	2A83.1	Bone marrow	1.30E-05	8.98E-01	2.72E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.42E-01	1.64E-01	6.40E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.13E-01	9.81E-02	2.35E-01
Myelofibrosis	2A20.2	Whole blood	2.24E-01	-9.75E-02	-2.30E-01
Myocardial infarction	BA41-BA50	Peripheral blood	2.36E-02	4.44E-01	4.90E-01
Myopathy	8C70.6	Muscle tissue	1.18E-04	8.85E-01	2.06E+00
Neonatal sepsis	KA60	Whole blood	6.81E-03	2.13E-01	3.77E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	6.38E-01	8.56E-02	1.50E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.11E-01	2.51E-01	9.78E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	7.95E-01	-4.05E-02	-6.34E-02
Olive pollen allergy	CA08.00	Peripheral blood	3.47E-01	-5.58E-01	-5.77E-01
Oral cancer	2B6E	Oral tissue	8.38E-28	1.79E+00	4.05E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	4.85E-01	9.77E-02	8.53E-02
Osteoporosis	FB83.1	Bone marrow	5.76E-01	-1.62E-01	-2.60E-01
Ovarian cancer	2C73	Ovarian tissue	1.65E-05	1.42E+00	3.11E+00
Pancreatic cancer	2C10	Pancreas	3.97E-02	3.51E-01	5.15E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	5.39E-01	-2.51E-01	-3.97E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.26E-02	8.48E-01	1.04E+00
Pituitary cancer	2D12	Pituitary tissue	5.30E-01	4.73E-02	5.42E-02
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.23E-01	-1.33E-01	-1.38E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.25E-01	3.80E-02	2.58E-01
Polycythemia vera	2A20.4	Whole blood	5.52E-01	1.47E-01	3.52E-01
Pompe disease	5C51.3	Biceps muscle	2.26E-01	2.87E-01	4.80E-01
Preterm birth	KA21.4Z	Myometrium	5.82E-02	-6.97E-01	-1.39E+00
Prostate cancer	2C82	Prostate	2.96E-01	-3.13E-01	-4.48E-01
Psoriasis	EA90	Skin	2.63E-19	4.61E-01	1.45E+00
Rectal cancer	2B92	Rectal colon tissue	7.83E-03	6.00E-01	1.59E+00
Renal cancer	2C90-2C91	Kidney	1.02E-01	4.70E-01	6.53E-01
Retinoblastoma	2D02.2	Uvea	5.41E-05	3.18E+00	1.14E+01
Rheumatoid arthritis	FA20	Synovial tissue	8.36E-09	1.26E+00	5.20E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	2.50E-01	-7.69E-02	-1.07E-01
Schizophrenia	6A20	Prefrontal cortex	3.08E-01	4.58E-02	5.35E-02
Schizophrenia	6A20	Superior temporal cortex	1.83E-01	3.21E-02	1.05E-01
Scleroderma	4A42.Z	Whole blood	8.54E-04	4.30E-01	1.53E+00
Seizure	8A60-8A6Z	Whole blood	8.85E-01	7.99E-02	8.64E-02
Sensitive skin	EK0Z	Skin	4.19E-01	5.64E-03	4.74E-02
Sepsis with septic shock	1G41	Whole blood	2.44E-02	2.40E-03	3.69E-03
Shwachman-Diamond syndrome	3A70.0	Bone marrow	6.70E-01	-1.91E-01	-9.84E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	9.40E-03	-2.69E-01	-6.35E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	4.09E-01	8.32E-02	3.92E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.72E-01	4.59E-01	1.03E+00
Skin cancer	2C30-2C3Z	Skin	1.66E-88	1.63E+00	4.23E+00
Thrombocythemia	3B63	Whole blood	3.04E-01	-1.26E-01	-2.97E-01
Thrombocytopenia	3B64	Whole blood	8.10E-01	1.48E-01	2.48E-01
Thyroid cancer	2D10	Thyroid	7.87E-07	7.00E-01	7.44E-01
Tibial muscular dystrophy	8C75	Muscle tissue	8.44E-01	-3.96E-02	-1.40E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.35E-02	-4.71E-01	-3.86E+00
Type 2 diabetes	5A11	Liver tissue	9.61E-02	2.55E-01	1.39E+00
Ureter cancer	2C92	Urothelium	4.21E-01	-7.31E-02	-9.23E-02
Uterine cancer	2C78	Endometrium tissue	4.01E-03	1.70E-01	2.59E-01
Vitiligo	ED63.0	Skin	7.68E-01	4.59E-03	2.65E-02