Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DER3H9C)

• DME Name: Lipocalin-type prostaglandin-D synthase (PTGDS) DME Info
• Gene Name: PTGDS

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.66E-02	-3.34E-01	-4.84E-01
Alopecia	ED70	Skin from scalp	7.55E-05	6.65E-01	1.15E+00
Alzheimer's disease	8A20	Entorhinal cortex	7.17E-02	4.48E-02	1.06E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.00E-01	-5.16E-02	-7.00E-02
Aortic stenosis	BB70	Calcified aortic valve	2.46E-03	-1.62E+00	-2.01E+00
Apnea	7A40	Hyperplastic tonsil	1.82E-01	9.26E-01	2.81E+00
Arthropathy	FA00-FA5Z	Peripheral blood	9.31E-01	1.88E-01	4.00E-01
Asthma	CA23	Nasal and bronchial airway	6.63E-01	2.88E-03	6.60E-03
Atopic dermatitis	EA80	Skin	2.23E-06	-6.74E-01	-1.60E+00
Autism	6A02	Whole blood	7.11E-01	7.10E-02	1.49E-01
Autoimmune uveitis	9A96	Peripheral monocyte	7.60E-02	-7.09E-02	-1.71E-01
Autosomal dominant monocytopenia	4B04	Whole blood	2.53E-01	-1.65E-01	-8.49E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.42E-16	1.11E+00	1.56E+00
Batten disease	5C56.1	Whole blood	9.27E-01	3.78E-01	6.22E-01
Behcet's disease	4A62	Peripheral blood	5.32E-01	3.92E-01	5.40E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.35E-01	4.31E-02	1.50E-01
Bladder cancer	2C94	Bladder tissue	3.14E-02	-1.58E+00	-1.27E+00
Breast cancer	2C60-2C6Z	Breast tissue	3.00E-36	-1.38E+00	-1.24E+00
Cardioembolic stroke	8B11.20	Whole blood	1.19E-01	-1.99E-01	-2.20E-01
Cervical cancer	2C77	Cervical tissue	3.46E-01	-4.98E-01	-5.39E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.12E-01	-1.60E-01	-3.51E-01
Chronic hepatitis C	1E51.1	Whole blood	6.46E-01	-9.69E-02	-1.84E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	7.54E-02	-2.70E-01	-3.43E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.05E-01	6.87E-03	2.64E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	2.93E-01	1.97E-01	1.12E+00
Colon cancer	2B90	Colon tissue	3.46E-03	-2.12E-01	-2.17E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	9.46E-03	4.85E-01	2.12E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.53E-01	-7.98E-02	-4.34E-01
Endometriosis	GA10	Endometrium tissue	9.95E-01	5.46E-01	3.10E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	1.10E-01	-4.36E-01	-7.71E-01
Familial hypercholesterolemia	5C80.00	Whole blood	4.81E-01	1.33E-01	2.51E-01
Gastric cancer	2B72	Gastric tissue	1.24E-01	-1.26E+00	-1.47E+00
Glioblastopma	2A00.00	Nervous tissue	1.56E-123	-2.04E+00	-2.06E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	1.29E-01	-1.21E+00	-2.33E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.15E-01	-8.89E-01	-1.05E+00
Head and neck cancer	2D42	Head and neck tissue	2.61E-01	4.84E-01	2.90E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.42E-01	5.65E-02	1.60E-01
Huntington's disease	8A01.10	Whole blood	2.33E-01	1.56E-01	2.21E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.44E-04	2.19E+00	3.95E+00
Immunodeficiency	4A00-4A20	Peripheral blood	1.73E-01	-3.34E-01	-8.86E-01
Influenza	1E30	Whole blood	2.88E-01	1.07E+00	1.05E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.49E-02	2.88E+00	1.97E+00
Intracranial aneurysm	8B01.0	Intracranial artery	6.82E-02	1.01E+00	8.46E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	6.65E-01	-2.42E-01	-3.04E-01
Ischemic stroke	8B11	Peripheral blood	8.17E-01	1.74E-01	2.26E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.77E-08	-8.10E-01	-1.03E+00
Lateral sclerosis	8B60.4	Skin	1.26E-01	3.66E-01	1.05E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	2.65E-01	-3.77E-01	-2.56E-01
Liver cancer	2C12.0	Liver tissue	3.19E-01	-7.93E-01	-1.37E+00
Liver failure	DB99.7-DB99.8	Liver tissue	8.43E-05	2.02E+00	5.48E+00
Lung cancer	2C25	Lung tissue	1.35E-88	-2.15E+00	-2.58E+00
Lupus erythematosus	4A40	Whole blood	6.68E-12	-5.90E-01	-7.91E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	1.33E-01	-7.21E-02	-2.58E-01
Major depressive disorder	6A70-6A7Z	Whole blood	8.22E-01	-2.78E-01	-3.36E-01
Melanoma	2C30	Skin	7.74E-03	-9.14E-01	-8.17E-01
Multiple myeloma	2A83.1	Peripheral blood	3.91E-01	7.85E-02	4.94E-02
Multiple myeloma	2A83.1	Bone marrow	1.50E-01	-7.52E-02	-2.64E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.11E-01	-2.52E-01	-3.70E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.32E-01	-1.14E-01	-4.12E-01
Myelofibrosis	2A20.2	Whole blood	5.85E-04	-8.50E-01	-2.21E+00
Myocardial infarction	BA41-BA50	Peripheral blood	1.81E-01	-2.40E-01	-3.42E-01
Myopathy	8C70.6	Muscle tissue	9.45E-02	6.19E-01	9.22E-01
Neonatal sepsis	KA60	Whole blood	2.02E-07	-4.04E-01	-8.41E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.73E-83	-4.69E+00	-5.16E+01
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.14E-01	3.14E-01	5.40E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	8.58E-01	-1.60E-01	-2.86E-01
Olive pollen allergy	CA08.00	Peripheral blood	6.56E-02	4.20E-01	1.38E+00
Oral cancer	2B6E	Oral tissue	2.29E-03	-9.35E-01	-8.99E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	7.40E-01	2.01E-01	1.59E-01
Osteoporosis	FB83.1	Bone marrow	9.64E-02	1.28E+00	1.22E+00
Ovarian cancer	2C73	Ovarian tissue	2.12E-01	3.35E-01	2.15E-01
Pancreatic cancer	2C10	Pancreas	3.03E-01	-6.08E-02	-4.64E-02
Parkinson's disease	8A00.0	Substantia nigra tissue	4.26E-01	-7.48E-02	-4.14E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	6.59E-01	-5.16E-02	-1.05E-01
Pituitary cancer	2D12	Pituitary tissue	2.53E-02	-8.33E-01	-4.09E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.88E-02	-1.14E+00	-5.34E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	3.80E-01	-1.44E-01	-3.47E-01
Polycythemia vera	2A20.4	Whole blood	8.99E-08	-4.50E-01	-1.15E+00
Pompe disease	5C51.3	Biceps muscle	1.89E-02	7.39E-01	1.72E+00
Preterm birth	KA21.4Z	Myometrium	9.20E-02	4.30E-01	1.12E+00
Prostate cancer	2C82	Prostate	5.10E-09	-9.25E-01	-1.24E+00
Psoriasis	EA90	Skin	2.53E-07	-5.81E-01	-8.34E-01
Rectal cancer	2B92	Rectal colon tissue	3.57E-02	-1.12E+00	-1.28E+00
Renal cancer	2C90-2C91	Kidney	4.79E-03	-2.17E+00	-1.71E+00
Retinoblastoma	2D02.2	Uvea	3.51E-06	-3.33E+00	-7.93E+00
Rheumatoid arthritis	FA20	Synovial tissue	4.62E-04	1.99E+00	2.54E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.16E-01	-7.93E-03	-5.08E-02
Schizophrenia	6A20	Prefrontal cortex	3.79E-02	2.36E-02	1.71E-02
Schizophrenia	6A20	Superior temporal cortex	1.45E-01	-6.68E-02	-2.06E-01
Scleroderma	4A42.Z	Whole blood	8.25E-05	-1.40E+00	-2.44E+00
Seizure	8A60-8A6Z	Whole blood	8.66E-01	1.80E-01	2.32E-01
Sensitive skin	EK0Z	Skin	3.89E-02	2.92E-01	1.14E+00
Sepsis with septic shock	1G41	Whole blood	1.26E-24	-4.76E-01	-1.09E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.42E-01	-4.70E-01	-1.27E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.50E-01	1.49E-01	4.84E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	6.98E-01	7.39E-02	2.04E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	6.39E-01	2.76E-02	4.37E-02
Skin cancer	2C30-2C3Z	Skin	4.45E-35	-1.62E+00	-1.71E+00
Thrombocythemia	3B63	Whole blood	1.98E-04	-4.23E-01	-1.08E+00
Thrombocytopenia	3B64	Whole blood	5.82E-01	3.79E-01	2.69E-01
Thyroid cancer	2D10	Thyroid	6.94E-11	-9.19E-01	-7.37E-01
Tibial muscular dystrophy	8C75	Muscle tissue	2.42E-05	1.81E+00	2.39E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.72E-01	7.70E-01	1.34E+00
Type 2 diabetes	5A11	Liver tissue	1.03E-01	3.81E-01	1.54E+00
Ureter cancer	2C92	Urothelium	8.13E-01	2.09E-02	8.98E-02
Uterine cancer	2C78	Endometrium tissue	2.40E-32	-2.45E+00	-1.50E+00
Vitiligo	ED63.0	Skin	9.30E-01	-2.42E-01	-2.31E-01