Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DERDQWN)

• DME Name: Dihydrotestosterone oxidoreductase (HSD3B1) DME Info
• Gene Name: HSD3B1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.96E-01	1.96E-03	1.58E-02
Alopecia	ED70	Skin from scalp	5.77E-02	3.26E-01	3.81E-01
Alzheimer's disease	8A20	Entorhinal cortex	5.19E-01	-3.04E-02	-2.43E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.50E-01	-1.85E-02	-1.69E-01
Aortic stenosis	BB70	Calcified aortic valve	8.27E-01	-9.50E-03	-2.46E-02
Apnea	7A40	Hyperplastic tonsil	3.00E-01	-6.01E-02	-6.05E-01
Arthropathy	FA00-FA5Z	Peripheral blood	1.10E-01	5.53E-02	6.89E-01
Asthma	CA23	Nasal and bronchial airway	7.48E-02	-6.14E-02	-4.02E-01
Atopic dermatitis	EA80	Skin	9.24E-01	-1.30E-01	-1.19E-01
Autism	6A02	Whole blood	4.82E-01	-1.61E-02	-1.16E-01
Autoimmune uveitis	9A96	Peripheral monocyte	7.42E-01	-2.41E-02	-1.66E-01
Autosomal dominant monocytopenia	4B04	Whole blood	4.99E-01	-2.40E-02	-1.52E-01
Bacterial infection of gingival	1C1H	Gingival tissue	7.16E-01	-3.52E-03	-1.53E-02
Batten disease	5C56.1	Whole blood	1.26E-01	-6.28E-03	-1.03E-01
Behcet's disease	4A62	Peripheral blood	6.29E-01	1.59E-02	1.28E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	3.17E-01	-5.00E-02	-5.42E-01
Bladder cancer	2C94	Bladder tissue	8.47E-09	4.84E-01	3.65E+00
Breast cancer	2C60-2C6Z	Breast tissue	2.82E-13	-1.63E-01	-4.26E-01
Cardioembolic stroke	8B11.20	Whole blood	4.74E-02	6.95E-02	4.71E-01
Cervical cancer	2C77	Cervical tissue	1.31E-01	-5.91E-02	-2.49E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	4.88E-01	5.54E-02	3.60E-01
Chronic hepatitis C	1E51.1	Whole blood	6.21E-02	1.53E-01	1.14E+00
Chronic obstructive pulmonary disease	CA22	Lung tissue	6.64E-03	8.78E-02	6.96E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	5.20E-01	1.07E-02	1.03E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	9.25E-01	4.08E-04	3.45E-03
Colon cancer	2B90	Colon tissue	4.07E-02	-8.92E-02	-2.45E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.56E-01	7.35E-02	4.57E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	1.69E-01	-6.31E-02	-6.04E-01
Endometriosis	GA10	Endometrium tissue	4.43E-02	1.13E-01	6.55E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.24E-01	2.00E-02	1.89E-01
Familial hypercholesterolemia	5C80.00	Whole blood	3.37E-04	-1.62E-01	-1.11E+00
Gastric cancer	2B72	Gastric tissue	8.59E-01	-2.54E-02	-1.44E-01
Glioblastopma	2A00.00	Nervous tissue	3.74E-01	6.21E-03	3.21E-02
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	2.76E-01	-3.55E-02	-1.63E+01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	3.30E-03	-2.35E-01	-1.69E+00
Head and neck cancer	2D42	Head and neck tissue	6.12E-01	2.10E-02	3.90E-02
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.65E-01	-3.76E-02	-1.33E-01
Huntington's disease	8A01.10	Whole blood	6.00E-02	1.15E-01	1.55E+00
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	8.99E-01	4.48E-02	3.04E-01
Immunodeficiency	4A00-4A20	Peripheral blood	2.33E-02	1.06E-01	1.21E+00
Influenza	1E30	Whole blood	1.01E-01	1.61E-01	1.51E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.16E-01	7.42E-02	1.65E+00
Intracranial aneurysm	8B01.0	Intracranial artery	2.12E-01	1.17E-01	6.83E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.56E-01	-8.52E-02	-3.77E-01
Ischemic stroke	8B11	Peripheral blood	9.10E-01	-2.73E-02	-2.09E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	2.56E-01	1.36E-02	7.20E-02
Lateral sclerosis	8B60.4	Skin	2.82E-01	4.24E-02	4.08E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	8.83E-01	-9.13E-02	-4.27E-01
Liver cancer	2C12.0	Liver tissue	5.15E-01	-7.33E-02	-2.40E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.30E-01	-1.36E-01	-3.15E-01
Lung cancer	2C25	Lung tissue	1.54E-03	2.68E-02	2.42E-01
Lupus erythematosus	4A40	Whole blood	1.47E-01	2.03E-02	9.20E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	8.14E-01	2.01E-02	2.55E-01
Major depressive disorder	6A70-6A7Z	Whole blood	3.19E-01	7.13E-03	3.56E-02
Melanoma	2C30	Skin	2.40E-05	-2.72E+00	-1.64E+00
Multiple myeloma	2A83.1	Peripheral blood	1.27E-02	1.35E-01	1.47E+00
Multiple myeloma	2A83.1	Bone marrow	6.87E-04	-2.97E-01	-1.62E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	6.74E-01	5.36E-02	4.46E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	7.37E-02	4.00E-02	3.18E-01
Myelofibrosis	2A20.2	Whole blood	4.31E-01	8.08E-03	9.91E-02
Myocardial infarction	BA41-BA50	Peripheral blood	4.25E-01	3.91E-02	1.30E-01
Myopathy	8C70.6	Muscle tissue	5.87E-01	-1.25E-02	-6.78E-02
Neonatal sepsis	KA60	Whole blood	2.82E-01	-3.84E-02	-2.74E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.43E-02	-2.19E-01	-1.03E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.38E-02	-4.16E-02	-5.13E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.47E-01	4.01E-02	3.75E-01
Olive pollen allergy	CA08.00	Peripheral blood	8.06E-02	1.02E-01	9.52E-01
Oral cancer	2B6E	Oral tissue	1.24E-02	-2.57E-01	-1.04E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.44E-01	-2.89E-03	-1.56E-02
Osteoporosis	FB83.1	Bone marrow	8.92E-01	6.12E-03	1.04E-01
Ovarian cancer	2C73	Ovarian tissue	8.24E-01	-1.46E-02	-5.85E-02
Pancreatic cancer	2C10	Pancreas	3.70E-02	-1.53E-01	-5.84E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	8.51E-01	-1.45E-03	-1.29E-02
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.17E-01	-3.10E-02	-3.38E-01
Pituitary cancer	2D12	Pituitary tissue	2.52E-01	-4.20E-02	-3.64E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.29E-01	-7.46E-02	-4.92E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.91E-01	6.49E-03	7.09E-02
Polycythemia vera	2A20.4	Whole blood	7.89E-02	2.83E-02	3.13E-01
Pompe disease	5C51.3	Biceps muscle	9.72E-02	6.02E-02	8.40E-01
Preterm birth	KA21.4Z	Myometrium	4.03E-01	-9.61E-02	-9.98E-02
Prostate cancer	2C82	Prostate	4.54E-02	-1.54E-01	-4.81E-01
Psoriasis	EA90	Skin	1.07E-15	-1.23E+00	-1.26E+00
Rectal cancer	2B92	Rectal colon tissue	7.75E-02	-2.30E-01	-1.36E+00
Renal cancer	2C90-2C91	Kidney	2.30E-01	-1.39E-01	-1.12E+00
Retinoblastoma	2D02.2	Uvea	8.64E-01	2.61E-02	2.88E-01
Rheumatoid arthritis	FA20	Synovial tissue	2.86E-01	-9.48E-02	-5.01E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.69E-01	4.77E-03	5.29E-02
Schizophrenia	6A20	Prefrontal cortex	2.84E-01	-8.57E-03	-6.45E-02
Schizophrenia	6A20	Superior temporal cortex	7.78E-01	4.16E-03	5.82E-02
Scleroderma	4A42.Z	Whole blood	4.05E-03	1.81E-01	1.87E+00
Seizure	8A60-8A6Z	Whole blood	5.00E-01	-4.88E-02	-3.60E-01
Sensitive skin	EK0Z	Skin	6.30E-01	-1.87E-01	-4.70E-01
Sepsis with septic shock	1G41	Whole blood	8.25E-02	1.54E-02	9.26E-02
Shwachman-Diamond syndrome	3A70.0	Bone marrow	9.28E-02	3.02E-01	1.57E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.49E-01	1.10E-02	7.03E-02
Simpson golabi behmel syndrome	LD2C	Adipose tissue	1.87E-01	-9.54E-02	-7.02E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.20E-01	-4.84E-02	-1.62E-01
Skin cancer	2C30-2C3Z	Skin	1.24E-36	-1.23E+00	-1.12E+00
Thrombocythemia	3B63	Whole blood	5.91E-01	2.72E-02	3.35E-01
Thrombocytopenia	3B64	Whole blood	8.45E-01	1.72E-02	1.11E-01
Thyroid cancer	2D10	Thyroid	1.09E-01	4.11E-02	2.52E-01
Tibial muscular dystrophy	8C75	Muscle tissue	5.08E-01	-9.14E-03	-6.31E-02
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	8.26E-02	2.09E-01	1.94E+00
Type 2 diabetes	5A11	Liver tissue	1.05E-01	9.62E-02	1.05E+00
Ureter cancer	2C92	Urothelium	7.21E-01	-1.21E-02	-8.92E-02
Uterine cancer	2C78	Endometrium tissue	5.41E-02	8.09E-02	3.63E-01
Vitiligo	ED63.0	Skin	5.97E-01	-4.31E-01	-3.85E-01