Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEU7MWJ)

• DME Name: Gamma-Glu-X carboxypeptidase (GGH) DME Info
• Gene Name: GGH

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	5.12E-01	5.13E-02	7.20E-02
Alopecia	ED70	Skin from scalp	1.13E-05	-2.19E-01	-6.78E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.52E-04	-2.37E-01	-5.07E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	4.66E-01	5.55E-02	2.40E-01
Aortic stenosis	BB70	Calcified aortic valve	6.28E-01	3.17E-01	2.68E-01
Apnea	7A40	Hyperplastic tonsil	8.31E-01	-3.17E-01	-2.76E-01
Arthropathy	FA00-FA5Z	Peripheral blood	2.06E-01	1.10E-01	4.16E-01
Asthma	CA23	Nasal and bronchial airway	2.27E-08	4.55E-01	3.63E-01
Atopic dermatitis	EA80	Skin	1.92E-01	-5.23E-01	-1.24E+00
Autism	6A02	Whole blood	1.01E-01	-2.78E-01	-4.39E-01
Autoimmune uveitis	9A96	Peripheral monocyte	2.74E-02	-2.19E-01	-6.02E-01
Autosomal dominant monocytopenia	4B04	Whole blood	4.10E-02	8.53E-01	1.60E+00
Bacterial infection of gingival	1C1H	Gingival tissue	7.16E-20	-8.95E-01	-1.67E+00
Batten disease	5C56.1	Whole blood	1.54E-01	-6.38E-01	-1.12E+00
Behcet's disease	4A62	Peripheral blood	1.62E-01	1.09E-01	2.71E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	2.78E-01	-1.50E-01	-3.51E-01
Bladder cancer	2C94	Bladder tissue	6.60E-05	2.20E+00	3.03E+00
Breast cancer	2C60-2C6Z	Breast tissue	3.52E-45	1.34E+00	1.43E+00
Cardioembolic stroke	8B11.20	Whole blood	1.13E-08	7.68E-01	2.06E+00
Cervical cancer	2C77	Cervical tissue	2.83E-04	6.74E-01	9.52E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.98E-01	-2.92E-01	-8.05E-01
Chronic hepatitis C	1E51.1	Whole blood	3.14E-01	1.57E-01	4.57E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	8.64E-01	-8.99E-02	-1.61E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.07E-02	-2.15E-01	-4.08E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.09E-01	1.79E-01	4.51E-01
Colon cancer	2B90	Colon tissue	2.84E-22	6.55E-01	1.18E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.01E-01	2.50E-01	4.17E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	6.06E-01	-3.33E-01	-4.75E-01
Endometriosis	GA10	Endometrium tissue	5.26E-03	-1.45E+00	-1.12E+00
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.44E-01	-1.81E-01	-2.84E-01
Familial hypercholesterolemia	5C80.00	Whole blood	4.97E-03	4.58E-01	1.33E+00
Gastric cancer	2B72	Gastric tissue	8.93E-02	2.58E+00	1.88E+00
Glioblastopma	2A00.00	Nervous tissue	8.97E-58	1.21E+00	1.26E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	5.17E-01	1.04E+00	8.40E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	5.34E-03	6.39E-01	7.50E-01
Head and neck cancer	2D42	Head and neck tissue	5.44E-26	1.27E+00	1.63E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.86E-01	-4.46E-01	-7.11E-01
Huntington's disease	8A01.10	Whole blood	3.78E-01	-1.02E-01	-1.05E+00
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	9.48E-05	8.71E-01	3.97E+00
Immunodeficiency	4A00-4A20	Peripheral blood	3.06E-03	8.68E-01	3.84E+00
Influenza	1E30	Whole blood	7.85E-03	-9.88E-01	-3.02E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.30E-02	9.87E-01	2.03E+00
Intracranial aneurysm	8B01.0	Intracranial artery	7.98E-03	7.86E-01	1.55E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.87E-01	-6.08E-02	-2.37E-01
Ischemic stroke	8B11	Peripheral blood	5.16E-01	2.13E-02	4.98E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.77E-02	1.11E-01	2.11E-01
Lateral sclerosis	8B60.4	Skin	1.88E-01	2.36E-01	1.02E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	3.48E-01	-8.78E-01	-6.23E-01
Liver cancer	2C12.0	Liver tissue	7.59E-03	6.06E-01	7.98E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.17E-04	-2.40E+00	-3.63E+00
Lung cancer	2C25	Lung tissue	9.32E-53	1.17E+00	1.87E+00
Lupus erythematosus	4A40	Whole blood	3.39E-11	4.89E-01	8.07E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	9.89E-01	-4.64E-02	-1.33E-01
Major depressive disorder	6A70-6A7Z	Whole blood	6.10E-01	-1.04E-02	-1.98E-02
Melanoma	2C30	Skin	1.67E-03	7.68E-01	1.01E+00
Multiple myeloma	2A83.1	Peripheral blood	5.55E-01	-1.99E-01	-9.11E-02
Multiple myeloma	2A83.1	Bone marrow	7.15E-20	2.51E+00	1.69E+01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.42E-01	-2.78E-01	-1.04E+00
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	3.11E-01	2.80E-02	1.07E-01
Myelofibrosis	2A20.2	Whole blood	1.29E-02	7.52E-01	4.28E+00
Myocardial infarction	BA41-BA50	Peripheral blood	6.97E-01	-8.36E-02	-9.27E-02
Myopathy	8C70.6	Muscle tissue	3.36E-03	9.08E-01	1.52E+00
Neonatal sepsis	KA60	Whole blood	6.04E-27	1.19E+00	2.12E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.27E-07	3.56E+00	4.27E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	7.34E-01	2.02E-01	5.37E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.21E-01	-5.73E-01	-2.11E+00
Olive pollen allergy	CA08.00	Peripheral blood	2.30E-01	-7.51E-01	-1.22E+00
Oral cancer	2B6E	Oral tissue	5.53E-07	1.71E+00	1.38E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	1.87E-01	1.21E+00	9.56E-01
Osteoporosis	FB83.1	Bone marrow	4.86E-03	-6.75E-01	-3.45E+00
Ovarian cancer	2C73	Ovarian tissue	1.75E-08	2.83E+00	6.16E+00
Pancreatic cancer	2C10	Pancreas	3.03E-04	6.56E-01	8.19E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	9.75E-01	-4.82E-01	-5.25E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	5.00E-05	5.75E-01	1.48E+00
Pituitary cancer	2D12	Pituitary tissue	1.39E-04	1.44E+00	2.66E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.12E-04	1.71E+00	2.77E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.42E-01	1.17E-01	5.27E-01
Polycythemia vera	2A20.4	Whole blood	2.07E-09	2.88E-01	1.35E+00
Pompe disease	5C51.3	Biceps muscle	7.35E-01	-1.20E-01	-3.28E-01
Preterm birth	KA21.4Z	Myometrium	1.78E-02	-5.14E-01	-1.22E+00
Prostate cancer	2C82	Prostate	1.82E-01	5.71E-01	4.78E-01
Psoriasis	EA90	Skin	1.09E-35	1.33E+00	2.36E+00
Rectal cancer	2B92	Rectal colon tissue	5.70E-02	4.52E-01	1.28E+00
Renal cancer	2C90-2C91	Kidney	5.99E-01	-3.05E-01	-2.66E-01
Retinoblastoma	2D02.2	Uvea	1.95E-03	9.04E-01	1.90E+00
Rheumatoid arthritis	FA20	Synovial tissue	3.38E-03	8.91E-01	1.72E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	9.20E-01	2.03E-02	4.12E-02
Schizophrenia	6A20	Prefrontal cortex	5.12E-03	-5.13E-01	-5.72E-01
Schizophrenia	6A20	Superior temporal cortex	7.45E-01	-1.07E-01	-2.30E-01
Scleroderma	4A42.Z	Whole blood	6.58E-01	-1.75E-01	-4.71E-01
Seizure	8A60-8A6Z	Whole blood	1.99E-01	3.46E-01	3.87E-01
Sensitive skin	EK0Z	Skin	2.04E-01	4.59E-01	1.49E+00
Sepsis with septic shock	1G41	Whole blood	2.32E-69	1.44E+00	2.32E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	6.10E-02	-4.86E-01	-1.18E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	6.87E-01	-1.19E-02	-1.97E-02
Simpson golabi behmel syndrome	LD2C	Adipose tissue	7.18E-01	-1.38E-01	-4.46E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.01E-01	-2.31E-01	-1.08E+00
Skin cancer	2C30-2C3Z	Skin	3.78E-17	6.49E-01	9.97E-01
Thrombocythemia	3B63	Whole blood	3.59E-03	1.32E-01	5.92E-01
Thrombocytopenia	3B64	Whole blood	7.40E-01	-2.78E-02	-3.58E-02
Thyroid cancer	2D10	Thyroid	2.81E-11	5.64E-01	8.65E-01
Tibial muscular dystrophy	8C75	Muscle tissue	4.93E-06	6.79E-01	1.60E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.60E-02	-6.09E-01	-3.54E+00
Type 2 diabetes	5A11	Liver tissue	4.12E-01	3.14E-01	1.58E+00
Ureter cancer	2C92	Urothelium	9.23E-01	-1.02E-01	-3.19E-01
Uterine cancer	2C78	Endometrium tissue	1.23E-22	1.70E+00	1.26E+00
Vitiligo	ED63.0	Skin	7.34E-01	2.40E-01	6.88E-01