Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEWJATF)

• DME Name: Adenosine 5'-monophosphoramidase (HINT1) DME Info
• Gene Name: HINT1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.64E-39	6.10E-01	2.62E+00
Alopecia	ED70	Skin from scalp	3.43E-01	6.05E-02	3.78E-01
Alzheimer's disease	8A20	Entorhinal cortex	3.97E-08	-3.71E-01	-1.10E+00
Ankylosing spondylitis	FA92.0	Pheripheral blood	3.54E-02	1.25E-01	6.85E-01
Aortic stenosis	BB70	Calcified aortic valve	9.05E-01	-6.15E-02	-5.80E-02
Apnea	7A40	Hyperplastic tonsil	4.27E-01	-2.36E-01	-3.16E-01
Arthropathy	FA00-FA5Z	Peripheral blood	7.18E-01	2.17E-02	3.07E-02
Asthma	CA23	Nasal and bronchial airway	2.01E-05	1.11E-01	2.99E-01
Atopic dermatitis	EA80	Skin	3.12E-02	-1.59E-01	-1.27E+00
Autism	6A02	Whole blood	2.71E-01	6.08E-01	6.85E-01
Autoimmune uveitis	9A96	Peripheral monocyte	3.21E-01	-3.92E-01	-1.20E+00
Autosomal dominant monocytopenia	4B04	Whole blood	2.50E-02	4.20E-01	6.59E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.28E-08	-1.96E-01	-9.33E-01
Batten disease	5C56.1	Whole blood	6.02E-01	-2.75E-02	-1.42E-01
Behcet's disease	4A62	Peripheral blood	2.22E-01	-1.24E-01	-6.88E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	7.05E-02	-8.84E-02	-3.17E-01
Bladder cancer	2C94	Bladder tissue	6.35E-01	3.49E-02	2.50E-01
Breast cancer	2C60-2C6Z	Breast tissue	5.02E-09	3.29E-01	9.74E-01
Cardioembolic stroke	8B11.20	Whole blood	1.49E-03	3.67E-01	1.01E+00
Cervical cancer	2C77	Cervical tissue	1.46E-01	1.15E-01	2.97E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.82E-01	-1.96E-01	-1.59E-01
Chronic hepatitis C	1E51.1	Whole blood	9.38E-01	-6.04E-02	-3.50E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.31E-01	-8.42E-02	-3.32E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	5.49E-01	7.25E-02	3.00E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	8.13E-01	-1.41E-01	-3.27E-01
Colon cancer	2B90	Colon tissue	1.25E-31	-1.66E-01	-1.06E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.49E-02	1.20E+00	2.91E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.64E-01	-1.30E-01	-5.02E-01
Endometriosis	GA10	Endometrium tissue	5.41E-03	-2.31E-01	-5.96E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.13E-01	-5.68E-03	-6.10E-02
Familial hypercholesterolemia	5C80.00	Whole blood	1.37E-14	1.13E+00	1.75E+00
Gastric cancer	2B72	Gastric tissue	7.54E-02	4.38E-01	1.92E+00
Glioblastopma	2A00.00	Nervous tissue	6.04E-48	-4.66E-01	-1.12E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	4.60E-02	-1.48E-01	-3.15E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.39E-06	9.70E-01	2.45E+00
Head and neck cancer	2D42	Head and neck tissue	9.22E-12	-2.25E-01	-8.80E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.77E-01	-2.24E-01	-4.45E-01
Huntington's disease	8A01.10	Whole blood	2.89E-01	-1.58E-01	-5.11E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	7.54E-02	1.70E-01	1.08E+00
Immunodeficiency	4A00-4A20	Peripheral blood	1.85E-01	-4.26E-03	-4.95E-02
Influenza	1E30	Whole blood	5.79E-01	1.16E-01	4.60E-01
Interstitial cystitis	GC00.3	Bladder tissue	3.88E-02	-2.28E-01	-1.39E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.80E-01	-1.50E-01	-7.07E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.18E-01	-1.62E-01	-7.34E-01
Ischemic stroke	8B11	Peripheral blood	2.51E-01	4.14E-02	2.03E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.98E-01	-7.34E-02	-1.20E-01
Lateral sclerosis	8B60.4	Skin	4.53E-02	1.40E-01	1.63E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	7.90E-01	3.62E-02	3.65E-02
Liver cancer	2C12.0	Liver tissue	7.67E-01	7.26E-02	2.68E-01
Liver failure	DB99.7-DB99.8	Liver tissue	8.18E-03	-7.03E-01	-5.15E+00
Lung cancer	2C25	Lung tissue	5.94E-02	6.47E-02	2.63E-01
Lupus erythematosus	4A40	Whole blood	4.57E-01	5.71E-01	5.72E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	7.90E-01	-1.09E-01	-4.68E-01
Major depressive disorder	6A70-6A7Z	Whole blood	6.47E-03	-1.27E-01	-2.54E-01
Melanoma	2C30	Skin	7.79E-03	-7.78E-02	-2.77E-01
Multiple myeloma	2A83.1	Peripheral blood	5.62E-01	2.80E-02	7.78E-02
Multiple myeloma	2A83.1	Bone marrow	6.07E-05	1.37E+00	3.42E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.32E-02	-2.82E-01	-1.61E+00
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.86E-01	-1.12E-02	-3.80E-02
Myelofibrosis	2A20.2	Whole blood	3.76E-01	1.67E-01	2.85E-01
Myocardial infarction	BA41-BA50	Peripheral blood	1.95E-02	-1.88E-01	-4.94E-01
Myopathy	8C70.6	Muscle tissue	2.80E-01	1.05E-01	9.73E-01
Neonatal sepsis	KA60	Whole blood	2.30E-01	-1.14E-01	-1.37E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	6.97E-05	7.15E-01	1.97E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	9.69E-01	-3.27E-02	-1.70E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	7.48E-05	-4.07E-01	-4.64E+00
Olive pollen allergy	CA08.00	Peripheral blood	8.59E-01	-3.98E-01	-4.35E-01
Oral cancer	2B6E	Oral tissue	5.14E-01	-7.62E-03	-1.93E-02
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.31E-01	2.60E-01	2.66E-01
Osteoporosis	FB83.1	Bone marrow	7.51E-02	-1.14E-01	-1.10E+00
Ovarian cancer	2C73	Ovarian tissue	3.32E-03	4.71E-01	1.46E+00
Pancreatic cancer	2C10	Pancreas	2.53E-01	2.36E-01	8.08E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	4.15E-01	-1.02E-01	-2.21E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.72E-04	-2.76E-01	-1.37E+00
Pituitary cancer	2D12	Pituitary tissue	1.83E-02	2.99E-01	1.36E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	5.99E-01	1.30E-01	6.06E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	3.77E-01	-9.73E-02	-5.84E-01
Polycythemia vera	2A20.4	Whole blood	2.95E-03	-3.36E-01	-5.74E-01
Pompe disease	5C51.3	Biceps muscle	1.49E-02	3.40E-01	4.08E+00
Preterm birth	KA21.4Z	Myometrium	3.04E-01	1.31E-01	1.12E+00
Prostate cancer	2C82	Prostate	1.51E-02	3.90E-02	1.64E-01
Psoriasis	EA90	Skin	8.71E-01	3.05E-02	1.61E-01
Rectal cancer	2B92	Rectal colon tissue	1.49E-03	-3.34E-01	-2.17E+00
Renal cancer	2C90-2C91	Kidney	7.66E-03	3.91E-01	1.50E+00
Retinoblastoma	2D02.2	Uvea	1.94E-02	4.03E-01	1.44E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.78E-02	2.61E-01	6.40E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.90E-01	2.25E-02	2.08E-01
Schizophrenia	6A20	Prefrontal cortex	3.28E-04	-1.37E-01	-4.44E-01
Schizophrenia	6A20	Superior temporal cortex	5.95E-01	-1.43E-01	-3.49E-01
Scleroderma	4A42.Z	Whole blood	8.93E-01	2.70E-01	5.25E-01
Seizure	8A60-8A6Z	Whole blood	4.06E-02	7.55E-01	8.73E-01
Sensitive skin	EK0Z	Skin	7.82E-01	3.22E-02	3.59E-01
Sepsis with septic shock	1G41	Whole blood	1.42E-04	-4.52E-01	-5.51E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.99E-03	-4.60E-01	-5.61E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	2.54E-02	-6.46E-01	-1.05E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.86E-01	3.84E-02	1.47E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.06E-01	-5.19E-01	-1.80E+00
Skin cancer	2C30-2C3Z	Skin	4.62E-18	-1.91E-01	-9.78E-01
Thrombocythemia	3B63	Whole blood	9.01E-03	-3.07E-01	-5.39E-01
Thrombocytopenia	3B64	Whole blood	3.62E-01	8.56E-02	2.74E-01
Thyroid cancer	2D10	Thyroid	4.33E-04	-9.68E-02	-3.81E-01
Tibial muscular dystrophy	8C75	Muscle tissue	8.31E-02	-4.89E-02	-2.26E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.32E-02	-5.83E-01	-2.56E+00
Type 2 diabetes	5A11	Liver tissue	6.58E-01	2.84E-02	2.87E-01
Ureter cancer	2C92	Urothelium	1.09E-01	3.22E-01	6.62E-01
Uterine cancer	2C78	Endometrium tissue	2.11E-04	-1.10E-01	-2.47E-01
Vitiligo	ED63.0	Skin	2.79E-01	2.47E-02	3.09E-01