Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEXHBCR)

• DME Name: S-methyl-5'-thioadenosine phosphorylase (MTAP) DME Info
• Gene Name: MTAP

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.10E-03	7.30E-02	3.48E-01
Alopecia	ED70	Skin from scalp	2.24E-01	-4.93E-02	-1.49E-01
Alzheimer's disease	8A20	Entorhinal cortex	7.11E-01	-3.06E-03	-2.36E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	6.27E-02	2.77E-01	1.30E+00
Aortic stenosis	BB70	Calcified aortic valve	5.18E-01	-5.63E-02	-4.97E-01
Apnea	7A40	Hyperplastic tonsil	6.57E-01	-2.01E-01	-1.09E+00
Arthropathy	FA00-FA5Z	Peripheral blood	6.11E-01	3.27E-02	1.84E-01
Asthma	CA23	Nasal and bronchial airway	2.89E-06	2.89E-01	7.17E-01
Atopic dermatitis	EA80	Skin	6.31E-01	-3.42E-02	-1.55E-01
Autism	6A02	Whole blood	3.78E-01	-1.50E-01	-8.29E-01
Autoimmune uveitis	9A96	Peripheral monocyte	5.45E-01	-4.83E-02	-2.74E-01
Autosomal dominant monocytopenia	4B04	Whole blood	6.86E-01	-4.74E-02	-3.55E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.44E-05	-1.08E-01	-4.52E-01
Batten disease	5C56.1	Whole blood	2.80E-01	-5.89E-02	-2.96E-01
Behcet's disease	4A62	Peripheral blood	6.15E-01	-6.25E-02	-2.78E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.02E-01	3.44E-02	2.52E-01
Bladder cancer	2C94	Bladder tissue	1.44E-02	-4.88E-01	-1.71E+00
Breast cancer	2C60-2C6Z	Breast tissue	5.58E-11	3.72E-02	1.78E-01
Cardioembolic stroke	8B11.20	Whole blood	7.14E-04	-2.63E-01	-9.10E-01
Cervical cancer	2C77	Cervical tissue	1.10E-02	2.30E-01	1.11E+00
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	2.55E-01	1.04E-01	3.19E-01
Chronic hepatitis C	1E51.1	Whole blood	5.76E-01	-5.73E-02	-3.83E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.83E-01	-1.54E-01	-5.66E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.40E-07	-1.61E-01	-7.46E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	7.91E-02	1.06E-01	1.35E+00
Colon cancer	2B90	Colon tissue	3.53E-78	4.74E-01	2.10E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	8.78E-01	3.74E-03	3.61E-02
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	2.59E-01	1.19E-01	7.41E-01
Endometriosis	GA10	Endometrium tissue	2.72E-01	-1.51E-01	-3.36E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	5.88E-01	-4.23E-02	-2.18E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.60E-01	-1.37E-02	-8.35E-02
Gastric cancer	2B72	Gastric tissue	1.35E-02	4.51E-01	3.33E+00
Glioblastopma	2A00.00	Nervous tissue	1.25E-46	2.54E-01	1.02E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	6.90E-01	7.52E-02	3.18E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	5.51E-03	1.69E-01	1.04E+00
Head and neck cancer	2D42	Head and neck tissue	1.52E-14	3.95E-01	1.91E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.44E-01	-1.12E-01	-8.55E-01
Huntington's disease	8A01.10	Whole blood	5.86E-01	3.71E-02	3.01E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	3.34E-01	-1.09E-01	-3.39E-01
Immunodeficiency	4A00-4A20	Peripheral blood	4.52E-01	1.26E-01	7.68E-01
Influenza	1E30	Whole blood	1.06E-02	-6.46E-01	-3.70E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.91E-02	-5.55E-01	-1.83E+00
Intracranial aneurysm	8B01.0	Intracranial artery	4.57E-01	1.27E-02	5.91E-02
Irritable bowel syndrome	DD91.0	Rectal colon tissue	3.23E-01	4.98E-02	2.83E-01
Ischemic stroke	8B11	Peripheral blood	9.58E-01	-6.62E-02	-2.61E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.15E-02	-9.61E-02	-3.16E-01
Lateral sclerosis	8B60.4	Skin	9.20E-02	2.52E-01	1.10E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	8.72E-01	1.85E-02	1.04E-01
Liver cancer	2C12.0	Liver tissue	2.09E-01	5.31E-02	1.79E-01
Liver failure	DB99.7-DB99.8	Liver tissue	8.11E-02	-1.63E-01	-1.13E+00
Lung cancer	2C25	Lung tissue	2.73E-28	2.29E-01	8.34E-01
Lupus erythematosus	4A40	Whole blood	9.31E-01	7.33E-02	1.72E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	4.68E-01	-1.12E-02	-7.93E-02
Major depressive disorder	6A70-6A7Z	Whole blood	9.78E-01	3.72E-02	1.25E-01
Melanoma	2C30	Skin	9.01E-02	1.82E-01	4.28E-01
Multiple myeloma	2A83.1	Peripheral blood	2.72E-01	-2.55E-01	-6.40E-01
Multiple myeloma	2A83.1	Bone marrow	5.96E-01	-3.65E-02	-2.32E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.81E-01	-6.84E-02	-2.78E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	1.79E-01	7.06E-02	1.60E-01
Myelofibrosis	2A20.2	Whole blood	4.14E-03	-1.96E-01	-1.27E+00
Myocardial infarction	BA41-BA50	Peripheral blood	3.38E-03	-2.57E-01	-6.04E-01
Myopathy	8C70.6	Muscle tissue	5.77E-01	1.01E-01	6.63E-01
Neonatal sepsis	KA60	Whole blood	1.55E-02	8.37E-02	3.72E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.61E-06	7.56E-01	2.99E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.77E-01	5.52E-02	5.51E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	6.79E-02	-1.15E-01	-1.01E+00
Olive pollen allergy	CA08.00	Peripheral blood	9.37E-01	-6.57E-03	-5.22E-02
Oral cancer	2B6E	Oral tissue	1.00E-05	2.67E-01	1.28E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.23E-01	5.84E-02	2.28E-01
Osteoporosis	FB83.1	Bone marrow	3.42E-01	-1.09E-01	-2.06E-01
Ovarian cancer	2C73	Ovarian tissue	2.55E-03	3.07E-01	1.34E+00
Pancreatic cancer	2C10	Pancreas	2.56E-01	-1.47E-01	-1.07E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	7.43E-01	1.20E-02	1.42E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	5.80E-01	-7.86E-03	-5.99E-02
Pituitary cancer	2D12	Pituitary tissue	9.66E-01	5.39E-03	2.73E-02
Pituitary gonadotrope tumour	2D12	Pituitary tissue	3.17E-01	-5.04E-03	-2.66E-02
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	5.83E-01	-1.39E-02	-1.95E-01
Polycythemia vera	2A20.4	Whole blood	4.71E-08	-1.48E-01	-1.42E+00
Pompe disease	5C51.3	Biceps muscle	7.90E-02	-8.41E-02	-4.75E-01
Preterm birth	KA21.4Z	Myometrium	7.77E-01	-5.49E-03	-1.56E-02
Prostate cancer	2C82	Prostate	3.44E-06	5.80E-01	1.47E+00
Psoriasis	EA90	Skin	3.40E-14	2.82E-01	9.41E-01
Rectal cancer	2B92	Rectal colon tissue	4.49E-04	3.11E-01	1.88E+00
Renal cancer	2C90-2C91	Kidney	3.17E-03	2.57E-01	1.25E+00
Retinoblastoma	2D02.2	Uvea	2.30E-05	1.12E+00	6.09E+00
Rheumatoid arthritis	FA20	Synovial tissue	3.69E-03	1.32E-01	7.13E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.31E-02	3.71E-02	2.41E-01
Schizophrenia	6A20	Prefrontal cortex	3.65E-01	-3.94E-02	-1.16E-01
Schizophrenia	6A20	Superior temporal cortex	9.79E-01	2.47E-02	2.08E-01
Scleroderma	4A42.Z	Whole blood	4.25E-02	7.64E-02	6.79E-01
Seizure	8A60-8A6Z	Whole blood	3.38E-01	-4.79E-02	-3.17E-01
Sensitive skin	EK0Z	Skin	7.22E-01	1.53E-01	6.59E-01
Sepsis with septic shock	1G41	Whole blood	1.23E-09	-1.37E-01	-5.86E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	4.79E-01	-1.33E-02	-6.07E-02
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	2.57E-01	8.75E-03	6.31E-02
Simpson golabi behmel syndrome	LD2C	Adipose tissue	1.49E-01	-1.23E-01	-5.52E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.33E-01	-6.47E-02	-6.54E-01
Skin cancer	2C30-2C3Z	Skin	1.57E-17	3.26E-01	1.05E+00
Thrombocythemia	3B63	Whole blood	9.32E-07	-1.37E-01	-1.27E+00
Thrombocytopenia	3B64	Whole blood	9.18E-01	5.24E-02	1.42E-01
Thyroid cancer	2D10	Thyroid	4.17E-05	8.58E-02	3.60E-01
Tibial muscular dystrophy	8C75	Muscle tissue	3.36E-02	-1.62E-01	-8.51E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	8.18E-01	2.69E-02	1.60E-01
Type 2 diabetes	5A11	Liver tissue	9.04E-01	-1.58E-01	-9.76E-01
Ureter cancer	2C92	Urothelium	5.64E-01	2.16E-02	1.72E-01
Uterine cancer	2C78	Endometrium tissue	2.02E-06	1.76E-01	5.87E-01
Vitiligo	ED63.0	Skin	7.23E-01	-1.72E-02	-6.78E-02